Imported endemic mycoses in Spain: Evolution of hospitalized cases, clinical characteristics and correlation with migratory movements, 1997-2014.

abstract：:The major arboviral diseases in mainland China include Japanese encephalitis, dengue fever, Crimean-Congo hemorrhagic fever (also known as Xinjiang hemorrhagic fever), and tick-borne encephalitis. These and other newly found arbovirus infections due to Banna virus and Tahyna virus contribute to a large and relatively ...

journal_title：PLoS neglected tropical diseases

authors： Gao X,Nasci R,Liang G

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:Canine rabies causes many thousands of human deaths every year in Africa, and continues to increase throughout much of the continent. METHODOLOGY/PRINCIPAL FINDINGS:This paper identifies four common reasons given for the lack of effective canine rabies control in Africa: (a) a low priority given for disease...

journal_title：PLoS neglected tropical diseases

authors： Lembo T,Hampson K,Kaare MT,Ernest E,Knobel D,Kazwala RR,Haydon DT,Cleaveland S

更新日期：2010-02-23 00:00:00

abstract：BACKGROUND:Human alveolar echinococcosis (AE) is known to be common in certain rural communities in China whilst it is generally rare and sporadic elsewhere. The objective of this study was to provide a first estimate of the global incidence of this disease by country. The second objective was to estimate the global di...

journal_title：PLoS neglected tropical diseases

authors： Torgerson PR,Keller K,Magnotta M,Ragland N

更新日期：2010-06-22 00:00:00

abstract：:Person-to-person transmission is a key feature of human Nipah virus outbreaks in Bangladesh. In contrast, in an outbreak of Nipah virus in Malaysia, people acquired infections from pigs. It is not known whether this important epidemiological difference is driven primarily by differences between NiV Bangladesh (NiV-BD)...

journal_title：PLoS neglected tropical diseases

authors： Clayton BA,Middleton D,Arkinstall R,Frazer L,Wang LF,Marsh GA

更新日期：2016-06-24 00:00:00

abstract：:Schistosomes are parasitic platyhelminths that currently infect over 200 million people globally. The parasites can live for years in a putatively hostile environment - the blood of vertebrates. We have hypothesized that the unusual schistosome tegument (outer-covering) plays a role in protecting parasites in the bloo...

journal_title：PLoS neglected tropical diseases

authors： Bhardwaj R,Skelly PJ

更新日期：2011-04-05 00:00:00

abstract：:Ebolaviruses pose a substantial threat to wildlife populations and to public health in Africa. Evolutionary analyses of virus genome sequences can contribute significantly to elucidate the origin of new outbreaks, which can help guide surveillance efforts. The reconstructed between-outbreak evolutionary history of Zai...

journal_title：PLoS neglected tropical diseases

authors： Vrancken B,Wawina-Bokalanga T,Vanmechelen B,Martí-Carreras J,Carroll MW,Nsio J,Kapetshi J,Makiala-Mandanda S,Muyembe-Tamfum JJ,Baele G,Vermeire K,Vergote V,Ahuka-Mundeke S,Maes P

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:The neglected tropical disease Buruli ulcer (BU) caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic ulcerative skin lesions. Histopathological features are progressive tissue necrosis, extracellular clusters of acid fast bacilli (AFB) and poor inflammatory response...

journal_title：PLoS neglected tropical diseases

authors： Ruf MT,Chauty A,Adeye A,Ardant MF,Koussemou H,Johnson RC,Pluschke G

更新日期：2011-08-01 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC), defined by their elaboration of heat-labile (LT) and/or heat-stable (ST) enterotoxins, are a common cause of diarrheal illness in developing countries. Efficient delivery of these toxins requires ETEC to engage target host enterocytes. This engagement is accomplished using a va...

journal_title：PLoS neglected tropical diseases

authors： Sheikh A,Rashu R,Begum YA,Kuhlman FM,Ciorba MA,Hultgren SJ,Qadri F,Fleckenstein JM

更新日期：2017-05-22 00:00:00

abstract：:For scientists working on gonochoric organisms, determining sex can be crucial for many biological questions and experimental studies, such as crossbreeding, but it can also be a challenging task, particularly when no sexual dimorphism is visible or cannot be directly observed. In metazoan parasites of the genus Schis...

journal_title：PLoS neglected tropical diseases

authors： Kincaid-Smith J,Boissier J,Allienne JF,Oleaga A,Djuikwo-Teukeng F,Toulza E

更新日期：2016-11-18 00:00:00

abstract：BACKGROUND:Monitoring of insect vector populations with respect to their susceptibility to one or more insecticides is a crucial element of the strategies used for the control of arthropod-borne diseases. This management task can nowadays be achieved more efficiently when assisted by IT (Information Technology) tools, ...

journal_title：PLoS neglected tropical diseases

authors： Dialynas E,Topalis P,Vontas J,Louis C

更新日期：2009-06-23 00:00:00

abstract：:Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patients with late cutaneous leishmaniasis. Although parasite DNA was found ...

journal_title：PLoS neglected tropical diseases

authors： Christensen SM,Dillon LA,Carvalho LP,Passos S,Novais FO,Hughitt VK,Beiting DP,Carvalho EM,Scott P,El-Sayed NM,Mosser DM

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to th...

journal_title：PLoS neglected tropical diseases

authors： Pinlaor P,Kaewpitoon N,Laha T,Sripa B,Kaewkes S,Morales ME,Mann VH,Parriott SK,Suttiprapa S,Robinson MW,To J,Dalton JP,Loukas A,Brindley PJ

更新日期：2009-01-01 00:00:00

abstract：:In Côte d'Ivoire, rabies is endemic and remains largely uncontrolled. The numbers of human exposures and rabies cases are unknown and are probably much higher than reported. Data on human rabies cases are collected by the National Institute of Public Health (NIPH) Anti-rabies Center in Abidjan through a network of 28 ...

journal_title：PLoS neglected tropical diseases

authors： Tiembré I,Broban A,Bénié J,Tetchi M,Druelles S,L'Azou M

更新日期：2018-09-06 00:00:00

abstract：:The progression and variation of pathology during infections can be due to components from both host or pathogen, and/or the interaction between them. The influence of host genetic variation on disease pathology during infections with trypanosomes has been well studied in recent years, but the role of parasite genetic...

journal_title：PLoS neglected tropical diseases

authors： Morrison LJ,Tait A,McLellan S,Sweeney L,Turner CM,MacLeod A

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Syphilis is resurgent in many regions of the world. Molecular typing is a robust tool for investigating strain diversity and epidemiology. This study aimed to review original research on molecular typing of Treponema pallidum (T. pallidum) with three objectives: (1) to determine specimen types most suitable ...

journal_title：PLoS neglected tropical diseases

authors： Peng RR,Wang AL,Li J,Tucker JD,Yin YP,Chen XS

更新日期：2011-11-01 00:00:00

abstract：:The current outbreak of Ebola Virus Disease in Upper West Africa is the largest ever recorded. Molecular evidence suggests spread has been almost exclusively through human-to-human contact. Social factors are thus clearly important to understand the epidemic and ways in which it might be stopped, but these factors hav...

journal_title：PLoS neglected tropical diseases

authors： Richards P,Amara J,Ferme MC,Kamara P,Mokuwa E,Sheriff AI,Suluku R,Voors M

更新日期：2015-04-17 00:00:00

abstract：:The Leishmania genus comprises up to 35 species, some with status still under discussion. The multilocus sequence typing (MLST)--extensively used for bacteria--has been proposed for pathogenic trypanosomatids. For Leishmania, however, a detailed analysis and revision on the taxonomy is still required. We have partiall...

journal_title：PLoS neglected tropical diseases

authors： Boité MC,Mauricio IL,Miles MA,Cupolillo E

更新日期：2012-01-01 00:00:00

abstract：:Entamoeba histolytica infection may have various clinical manifestations. Nine out of ten E. histolytica infections remain asymptomatic, while the remainder become invasive and cause disease. The most common form of invasive infection is amebic diarrhea and colitis, whereas the most common extra-intestinal disease is ...

journal_title：PLoS neglected tropical diseases

authors： Ali IK,Solaymani-Mohammadi S,Akhter J,Roy S,Gorrini C,Calderaro A,Parker SK,Haque R,Petri WA Jr,Clark CG

更新日期：2008-04-09 00:00:00

abstract：BACKGROUND:Anti-leishmanial drug regimens that include a single dose AmBisome could be suitable for eastern African patients with symptomatic visceral leishmaniasis (VL) but the appropriate single dose is unknown. METHODOLOGY:A multi-centre, open-label, non-inferiority, randomized controlled trial with an adaptive des...

journal_title：PLoS neglected tropical diseases

authors： Khalil EA,Weldegebreal T,Younis BM,Omollo R,Musa AM,Hailu W,Abuzaid AA,Dorlo TP,Hurissa Z,Yifru S,Haleke W,Smith PG,Ellis S,Balasegaram M,EL-Hassan AM,Schoone GJ,Wasunna M,Kimutai R,Edwards T,Hailu A

更新日期：2014-01-16 00:00:00

abstract：:Infection with filarial parasites is associated with T cell hyporesponsiveness, which is thought to be partly mediated by their ability to induce regulatory T cells (Tregs) during human infections. This study investigates the functional capacity of Tregs from different groups of filarial patients to suppress filaria-s...

journal_title：PLoS neglected tropical diseases

authors： Wammes LJ,Hamid F,Wiria AE,Wibowo H,Sartono E,Maizels RM,Smits HH,Supali T,Yazdanbakhsh M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Rabies is a fatal encephalitis caused by viruses belonging to the genus Lyssavirus of the family Rhabdoviridae. It is a viral disease primarily affecting mammals, though all warm blooded animals are susceptible. Experimental rabies virus infection in birds has been reported, but naturally occurring infection...

journal_title：PLoS neglected tropical diseases

authors： Baby J,Mani RS,Abraham SS,Thankappan AT,Pillai PM,Anand AM,Madhusudana SN,Ramachandran J,Sreekumar S

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Trachoma prevalence surveys provide the evidence base for district and community-wide implementation of the SAFE strategy, and are used to evaluate the impact of trachoma control interventions. An economic analysis was performed to estimate the cost of trachoma prevalence surveys conducted between 2006 and 2...

journal_title：PLoS neglected tropical diseases

authors： Chen C,Cromwell EA,King JD,Mosher A,Harding-Esch EM,Ngondi JM,Emerson PM

更新日期：2011-03-08 00:00:00

abstract：BACKGROUND:The dengue virus is endemic in many low- and middle-income countries. In Burkina Faso, the proportion of fevers that could be due to dengue is growing. In 2013, a dengue epidemic spread there, followed by other seasonal outbreaks. Dengue is often confused with malaria, and health workers are not trained to d...

journal_title：PLoS neglected tropical diseases

authors： Hébert C,Dagenais C,Mc Sween-Cadieux E,Ridde V

更新日期：2020-06-10 00:00:00

abstract：:The World Health Organization (WHO) defines an effective round of mass drug administration (MDA) for lymphatic filariasis (LF) as one that reaches at least 65% of the target population. In its first round of MDA in 2011-2012, the National Program to Eliminate LF in Haiti achieved a 79% epidemiological coverage in urba...

journal_title：PLoS neglected tropical diseases

authors： Wodnik BK,Louis DH,Joseph M,Wilkers LT,Landskroener SD,Desir L,Lemoine JF,Lavery JV

更新日期：2020-05-29 00:00:00

abstract：:Parasites of the Leishmania genus can rapidly alter several macrophage (MØ) signalling pathways in order to tame down the innate immune response and inflammation, therefore favouring their survival and propagation within their mammalian host. Having recently reported that Leishmania and bacterial LPS generate a signif...

journal_title：PLoS neglected tropical diseases

authors： Abu-Dayyeh I,Shio MT,Sato S,Akira S,Cousineau B,Olivier M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Skin sores caused by Group A streptococcus (GAS) infection are a major public health problem in remote Aboriginal communities. Skin sores are often associated with scabies, which is evident in scabies intervention programs where a significant reduction of skin sores is seen after focusing solely on scabies c...

journal_title：PLoS neglected tropical diseases

authors： Aung PTZ,Cuningham W,Hwang K,Andrews RM,Carapetis JR,Kearns T,Clucas D,McVernon J,Simpson JA,Tong SYC,Campbell PT

更新日期：2018-07-25 00:00:00

abstract：BACKGROUND:Leishmania development in the sand fly gut leads to highly infective forms called metacyclic promastigotes. This process can be routinely mimicked in culture. Gene expression-profiling studies by transcriptome analysis have been performed with the aim of studying promastigote forms in the sand fly gut, as we...

journal_title：PLoS neglected tropical diseases

authors： Alcolea PJ,Alonso A,Molina R,Jiménez M,Myler PJ,Larraga V

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Mosquito-borne viral diseases cause significant burden in much of the developing world. Although host-virus interactions have been studied extensively in the vertebrate host, little is known about mosquito responses to viral infection. In contrast to mosquitoes of the Aedes and Culex genera, Anopheles gambia...

journal_title：PLoS neglected tropical diseases

authors： Waldock J,Olson KE,Christophides GK

更新日期：2012-01-01 00:00:00

abstract：:The causative agent of cholera, Vibrio cholerae, regulates its diverse virulence factors to thrive in the human small intestine and environmental reservoirs. Among this pathogen's arsenal of virulence factors is the tightly regulated type VI secretion system (T6SS). This system acts as an inverted bacteriophage to inj...

journal_title：PLoS neglected tropical diseases

authors： Bachmann V,Kostiuk B,Unterweger D,Diaz-Satizabal L,Ogg S,Pukatzki S

更新日期：2015-08-28 00:00:00

abstract：:To control and prevent rabies in Latin America, mass dog vaccination campaigns (MDVC) are implemented mainly through fixed-location vaccination points: owners have to bring their dogs to the vaccination points where they receive the vaccination free of charge. Dog rabies is still endemic in some Latin-American countri...

journal_title：PLoS neglected tropical diseases

authors： Castillo-Neyra R,Toledo AM,Arevalo-Nieto C,MacDonald H,De la Puente-León M,Naquira-Velarde C,Paz-Soldan VA,Buttenheim AM,Levy MZ

更新日期：2019-08-01 00:00:00