Caregivers' views on stigmatization and discrimination of people affected by leprosy in Ghana.

abstract：BACKGROUND:Urinary Schistosomiasis is a neglected tropical disease endemic in many sub Saharan -African countries. Collectin Kidney 1 (CL-K1, encoded by COLEC11 on chromosome 2p25.3), a member of the vertebrate C-type lectin super family, has recently been identified as pattern-recognition molecule (PRR) of the lectin ...

journal_title：PLoS neglected tropical diseases

authors： Antony JS,Ojurongbe O,Kremsner PG,Velavan TP

更新日期：2015-03-25 00:00:00

abstract：:Buruli ulcer (BU) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans. It is the third most common human mycobacterial disease after tuberculosis (TB) and leprosy. The available methods for detection of the bacilli in lesions are microscopic detection, isolation and cultivation of the bac...

journal_title：PLoS neglected tropical diseases

authors： Avumegah MS,Waidyatillake NT,Michalski WP,O'Brien DP,Nelson TM,Athan E

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:In mass vaccination campaigns, large volumes of data must be managed efficiently and accurately. In a reactive oral cholera vaccination (OCV) campaign in rural Haiti during an ongoing epidemic, we used a mobile health (mHealth) system to manage data on 50,000 participants in two isolated communities. METHOD...

journal_title：PLoS neglected tropical diseases

authors： Teng JE,Thomson DR,Lascher JS,Raymond M,Ivers LC

更新日期：2014-07-31 00:00:00

abstract：:Non-typhoidal Salmonella (NTS) is a major global health concern that often causes bloodstream infections in areas of the world affected by malnutrition and comorbidities such as HIV and malaria. Developing a strategy to control the emergence and spread of highly invasive and antimicrobial resistant NTS isolates requir...

journal_title：PLoS neglected tropical diseases

authors： Kubicek-Sutherland JZ,Xie G,Shakya M,Dighe PK,Jacobs LL,Daligault H,Davenport K,Stromberg LR,Stromberg ZR,Cheng Q,Kempaiah P,Ong'echa JM,Otieno V,Raballah E,Anyona S,Ouma C,Chain PSG,Perkins DJ,Mukundan H,McMahon BH

更新日期：2021-02-01 00:00:00

abstract：:[This corrects the article DOI: 10.1371/journal.pntd.0005125.]. ...

journal_title：PLoS neglected tropical diseases

authors： PLOS Neglected Tropical Diseases Staff.

更新日期：2017-01-31 00:00:00

abstract：BACKGROUND:Cryptosporidium is a protozoan parasite that causes mild to severe diarrhoeal disease in humans. To date, several commercial companies have developed rapid immunoassays for the detection of Cryptosporidium infection. However, the challenge is to identify an accurate, simple and rapid diagnostic tool for the ...

journal_title：PLoS neglected tropical diseases

authors： Manouana GP,Lorenz E,Mbong Ngwese M,Nguema Moure PA,Maiga Ascofaré O,Akenten CW,Amuasi J,Rakotozandrindrainy N,Rakotozandrindrainy R,Mbwana J,Lusingu J,Byrne N,Melhem S,Zinsou JF,Adegbite RB,Hogan B,Winter D,May J,Kre

更新日期：2020-07-13 00:00:00

abstract：:Dengue continues to be the most important vector-borne viral disease globally and in Brazil, where more than 1.4 million cases and over 500 deaths were reported in 2016. Mosquito control programmes and other interventions have not stopped the alarming trend of increasingly large epidemics in the past few years. Here, ...

journal_title：PLoS neglected tropical diseases

authors： Churakov M,Villabona-Arenas CJ,Kraemer MUG,Salje H,Cauchemez S

更新日期：2019-04-22 00:00:00

abstract：BACKGROUND:Miltefosine (MIL) is an oral antileishmanial drug used for treatment of visceral leishmaniasis (VL) in the Indian subcontinent. Recent reports indicate a significant decline in its efficacy with a high rate of relapse in VL as well as post kala-azar dermal leishmaniasis (PKDL). We investigated the parasitic ...

journal_title：PLoS neglected tropical diseases

authors： Deep DK,Singh R,Bhandari V,Verma A,Sharma V,Wajid S,Sundar S,Ramesh V,Dujardin JC,Salotra P

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Rift Valley fever virus (RVFV) causes outbreaks of severe disease in livestock and humans throughout Africa and the Arabian Peninsula. In people, RVFV generally causes a self-limiting febrile illness but in a subset of individuals, it progresses to more serious disease. One manifestation is a delayed-onset e...

journal_title：PLoS neglected tropical diseases

authors： Dodd KA,McElroy AK,Jones TL,Zaki SR,Nichol ST,Spiropoulou CF

更新日期：2014-06-12 00:00:00

abstract：:Chikungunya virus (CHIKV), an alphavirus that causes fever and severe polyarthralgia, swept through the Americas in 2014 with almost 2 million suspected or confirmed cases reported by April 2016. In this study, we estimate the direct medical costs, cost of lost wages due to absenteeism, and years lived with disability...

journal_title：PLoS neglected tropical diseases

authors： Feldstein LR,Ellis EM,Rowhani-Rahbar A,Hennessey MJ,Staples JE,Halloran ME,Weaver MR

更新日期：2019-07-19 00:00:00

abstract：:The human gut has been continuously exposed to a broad spectrum of intestinal organisms, including viruses, bacteria, fungi, and parasites (protozoa and worms), over millions of years of coevolution, and plays a central role in human health. The modern lifestyles of Western countries, such as the adoption of highly hy...

journal_title：PLoS neglected tropical diseases

authors： Marzano V,Mancinelli L,Bracaglia G,Del Chierico F,Vernocchi P,Di Girolamo F,Garrone S,Tchidjou Kuekou H,D'Argenio P,Dallapiccola B,Urbani A,Putignani L

更新日期：2017-11-02 00:00:00

abstract：BACKGROUND:Large-scale deworming programs have, to date, mostly targeted preschool- and school-age children. As community-based deworming programs become more common, deworming will be offered to women of reproductive age. The World Health Organization recommends preventive chemotherapy be administered to pregnant wome...

journal_title：PLoS neglected tropical diseases

authors： St-Denis K,Blouin B,Rahme E,Casapia M,Montresor A,Mupfasoni D,Mbabazi PS,Gyorkos TW

更新日期：2020-01-30 00:00:00

abstract：:Chikungunya virus (CHIKV) infection is characterized by rash, acute high fever, chills, headache, nausea, photophobia, vomiting, and severe polyarthralgia. There is evidence that arthralgia can persist for years and result in long-term discomfort. Neurologic disease with fatal outcome has been documented, although at ...

journal_title：PLoS neglected tropical diseases

authors： van den Doel P,Volz A,Roose JM,Sewbalaksing VD,Pijlman GP,van Middelkoop I,Duiverman V,van de Wetering E,Sutter G,Osterhaus AD,Martina BE

更新日期：2014-09-04 00:00:00

abstract：BACKGROUND:Dengue is a mosquito-borne viral disease caused by four closely related serotypes of Dengue viruses (DENVs). This disease whose symptoms range from mild fever to potentially fatal haemorrhagic fever and hypovolemic shock, threatens nearly half the global population. There is neither a preventive vaccine nor ...

journal_title：PLoS neglected tropical diseases

authors： Korrapati AB,Swaminathan G,Singh A,Khanna N,Swaminathan S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Treatment needs for Schistosoma haematobium are commonly evaluated using urine filtration with detection of parasite eggs under a microscope. A common symptom of S. haematobium is hematuria, the passing of blood in urine. Hence, the use of hematuria-based diagnostic techniques as a proxy for the assessment o...

journal_title：PLoS neglected tropical diseases

authors： Midzi N,Bärenbold O,Manangazira P,Phiri I,Mutsaka-Makuvaza MJ,Mhlanga G,Utzinger J,Vounatsou P

更新日期：2020-08-20 00:00:00

abstract：:Digestive and cardiodigestive forms of Chagas' disease are observed in 2% to 27% of the patients, depending on their geographic location, Trypanosoma cruzi strain and immunopathological responses. The aim of this work was to evaluate the role of NOD2 innate immune receptor in the pathogenesis of the digestive system i...

journal_title：PLoS neglected tropical diseases

authors： Pereira NS,Queiroga TBD,da Silva DD,Nascimento MSL,Andrade CM,Souto JT,Ricci MF,Arantes RME,Zamboni DS,Chiari E,Câmara ACJD,Galvão LMDC,Guedes PMM

更新日期：2020-09-28 00:00:00

abstract：:In French Guiana, from 1984 to 2011, 14 animal rabies cases and 1 human rabies case (2008) were diagnosed. In January 2011, vampire-bat attacks occurred in 2 isolated villages. In mid-January, a medical team from the Cayenne Centre for Anti-Rabies Treatment visited the sites to manage individuals potentially exposed t...

journal_title：PLoS neglected tropical diseases

authors： Berger F,Desplanches N,Baillargeaux S,Joubert M,Miller M,Ribadeau-Dumas F,Spiegel A,Bourhy H

更新日期：2013-06-27 00:00:00

abstract：:Mycetoma is considered a neglected tropical disease globally. However, data on its burden and the associated complications in Uganda are limited. Hence we aimed to estimate its burden in Uganda. Firstly, a systematic PubMed search for all studies of any design on mycetoma in Uganda without restriction to the year of p...

journal_title：PLoS neglected tropical diseases

authors： Kwizera R,Bongomin F,Meya DB,Denning DW,Fahal AH,Lukande R

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Between 20 and 30 bacteriologically confirmed cases of leprosy are diagnosed each year at the French National Reference Center for mycobacteria. Patients are mainly immigrants from various endemic countries or living in French overseas territories. We aimed at expanding data regarding the geographical distri...

journal_title：PLoS neglected tropical diseases

authors： Reibel F,Chauffour A,Brossier F,Jarlier V,Cambau E,Aubry A

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Our earlier genome-wide expression study revealed up-regulation of a tryptophan-catabolizing enzyme, indoleamine 2,3-dioxygenase (IDO1), in patients with scrub typhus. This gene has been previously reported to have anti-microbial activity in a variety of infectious diseases; therefore, we aimed to prove whet...

journal_title：PLoS neglected tropical diseases

authors： Prachason T,Konhan K,Pongnarin P,Chatsiricharoenkul S,Suputtamongkol Y,Limwongse C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Aedes aegypti, the "yellow fever mosquito", is the primary vector to humans of the four serotypes of dengue viruses (DENV1-4) and yellow fever virus (YFV) and is a known vector of Chikungunya virus. There are two recognized subspecies of Ae. aegypti sensu latu (s.l.): the presumed ancestral form, Ae. aegypti...

journal_title：PLoS neglected tropical diseases

authors： Sylla M,Bosio C,Urdaneta-Marquez L,Ndiaye M,Black WC 4th

更新日期：2009-01-01 00:00:00

abstract：:Aedes aegypti is the primary vector of several medically relevant arboviruses including dengue virus (DENV) types 1-4. Ae. aegypti transmits DENV by inoculating virus-infected saliva into host skin during probing and feeding. Ae. aegypti saliva contains over one hundred unique proteins and these proteins have diverse ...

journal_title：PLoS neglected tropical diseases

authors： Conway MJ,Londono-Renteria B,Troupin A,Watson AM,Klimstra WB,Fikrig E,Colpitts TM

更新日期：2016-09-15 00:00:00

abstract：:Rift Valley fever (RVF) is endemic in most parts of Africa and has also been reported to occur in the Arabian Peninsula. It is responsible for significant morbidity and mortality, particularly in livestock, but also in humans. During the last two decades several outbreaks of RVF have been reported in countries in Sout...

journal_title：PLoS neglected tropical diseases

authors： Fafetine J,Neves L,Thompson PN,Paweska JT,Rutten VP,Coetzer JA

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Pathogenesis of severe fever with thrombocytopenia syndrome (SFTS) has not been well described yet. Recent studies indicate that SFTSV could replicate in endothelial cells. Here we performed a case-control study to determine whether endothelial activation/dysfunction occurred in SFTSV infection and to identi...

journal_title：PLoS neglected tropical diseases

authors： Li XK,Yang ZD,Du J,Xing B,Cui N,Zhang PH,Li H,Zhang XA,Lu QB,Liu W

更新日期：2017-08-14 00:00:00

abstract：BACKGROUND:Trachoma programs rely on guidelines made in large part using expert opinion of what will happen with and without intervention. Large community-randomized trials offer an opportunity to actually compare forecasting methods in a masked fashion. METHODS:The Program for the Rapid Elimination of Trachoma trials...

journal_title：PLoS neglected tropical diseases

authors： Liu F,Porco TC,Amza A,Kadri B,Nassirou B,West SK,Bailey RL,Keenan JD,Solomon AW,Emerson PM,Gambhir M,Lietman TM

更新日期：2015-08-24 00:00:00

abstract：:In the current study, a comprehensive, data driven, mathematical model for cholera transmission in Haiti is presented. Along with the inclusion of short cycle human-to-human transmission and long cycle human-to-environment and environment-to-human transmission, this novel dynamic model incorporates both the reported c...

journal_title：PLoS neglected tropical diseases

authors： Kirpich A,Weppelmann TA,Yang Y,Ali A,Morris JG Jr,Longini IM

更新日期：2015-10-21 00:00:00

abstract：BACKGROUND:Human echinococcosis is a neglected zoonosis caused by parasites of the genus Echinococcus. The most frequent clinical forms of echinococcosis, cystic echinococcosis (CE) and alveolar echinococcosis (AE), are responsible for a substantial health and economic burden, particularly to low-income societies. Quan...

journal_title：PLoS neglected tropical diseases

authors： Otero-Abad B,Torgerson PR

更新日期：2013-06-06 00:00:00

abstract：INTRODUCTION:Individuals exposed to malaria infections for a long time develop immune responses capable of blocking Plasmodium transmission to mosquito vectors, potentially limiting parasite spreading in nature. Development of a malaria TB vaccine requires a better understanding of the mechanisms and main effectors res...

journal_title：PLoS neglected tropical diseases

authors： Vallejo AF,Rubiano K,Amado A,Krystosik AR,Herrera S,Arévalo-Herrera M

更新日期：2016-06-29 00:00:00

abstract：BACKGROUND:Zika (ZIKV) and Chikungunya (CHIKV) viruses are emerging Aedes-borne viruses that are spreading outside their known geographic range and causing wide-scale epidemics. It has been reported that these viruses can be transmitted efficiently by Ae. aegypti. Recent studies have shown that Ae. aegypti when transin...

journal_title：PLoS neglected tropical diseases

authors： Tan CH,Wong PJ,Li MI,Yang H,Ng LC,O'Neill SL

更新日期：2017-05-19 00:00:00

abstract：BACKGROUND:Trypanosomiasis induces a remarkable myenteric neuronal degeneration leading to megacolon. Very little is known about the risk for colon cancer in chagasic megacolon patients. To clarify whether chagasic megacolon impacts on colon carcinogenesis, we investigated the risk for colon cancer in Trypanosoma cruzi...

journal_title：PLoS neglected tropical diseases

authors： Kannen V,de Oliveira EC,Motta BZ,Chaguri AJ,Brunaldi MO,Garcia SB

更新日期：2015-04-17 00:00:00