Abstract：
BACKGROUND:There is a controversy about self-monitoring of blood glucose (SMBG) in patients with type 2 diabetes who are not using insulin. Randomized trials are limited in duration, size, and validity. METHODS:Systematic search for randomized trials and observational studies published since 1990. For inclusion studies had to report on SMBG in type 2 diabetes managed with oral hypoglycaemic agents and/or diet alone, HbA(1c) or clinical outcome, have at least 50 patients and be of at least 6 months' duration. RESULTS:Three randomized trials with 1000 patients were included, though all had interventions differing in the amount of education on SMBG, and in the population studied. The two larger studies had statistically significantly lower HbA(1c) levels with SMBG. Thirteen observational studies had information on over 60,000 patients. Smaller studies had lower initial HbA(1c) and showed no association between SMBG and laboratory or clinical improvement. Larger studies tended to have higher initial HbA(1c) and did show an association between SMBG and laboratory or clinical improvement. Overall, improvement in glycaemic control with SMBG tended to be seen in studies with initial HbA(1c) above 8%. CONCLUSIONS:It is likely that SMBG is beneficial in some circumstances, for example as an educational tool, for patients with type 2 diabetes not using insulin who have poor glycaemic control. More information is needed at the level of the individual patient, rather than group means, and about timing and frequency of monitoring, response to those results, what constitutes effective patient education, and long-term clinical outcomes.
journal_name
Diabetes Metab Res Revjournal_title
Diabetes/metabolism research and reviewsauthors
McGeoch G,Derry S,Moore RAdoi
10.1002/dmrr.749subject
Has Abstractpub_date
2007-09-01 00:00:00pages
423-40issue
6eissn
1520-7552issn
1520-7560journal_volume
23pub_type
杂志文章,评审abstract：:During the last decades, the central nervous system (CNS) was intensively tested as a site for islet transplantation in different animal models of diabetes. Immunoprivilege properties of intracranial and intrathecal sites were found to delay and reduce rejection of transplanted allo-islets and xeno-islets, especially ...
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pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
abstract：:Diabetes mellitus is one of the most challenging health concerns of the 21st century. With at least 30% of the diabetic population remaining undiagnosed, effective and early diagnosis is of critical concern. Development of a diagnostic test, more convenient and reliable than those currently used, would therefore be hi...
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更新日期：2008-07-01 00:00:00
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journal_title：Diabetes/metabolism research and reviews
pub_type： 杂志文章,随机对照试验
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更新日期：2007-05-01 00:00:00
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journal_title：Diabetes/metabolism research and reviews
pub_type： 杂志文章
doi：10.1002/dmrr.2325
更新日期：2012-11-01 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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更新日期：2012-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2015-03-01 00:00:00
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更新日期：2007-09-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2016-01-01 00:00:00
abstract：:The increasing global prevalence of type 2 diabetes mellitus (T2DM) requires the implementation of preventive strategies to halt this trend, tailored to the specific needs of individual regions. Risk factors for T2DM are among the main targets for improving health outcomes and curbing the development of diabetes; exce...
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pub_type： 杂志文章
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更新日期：2007-07-01 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2016-05-01 00:00:00
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更新日期：2005-05-01 00:00:00
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更新日期：2019-09-01 00:00:00
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更新日期：2019-11-01 00:00:00
