Integration of Descending Command Systems for the Generation of Context-Specific Locomotor Behaviors.

abstract：:Identifying the multiple contributors to the audiometric loss of a hearing impaired (HI) listener at a particular frequency is becoming gradually more useful as new treatments are developed. Here, we infer the contribution of inner (IHC) and outer hair cell (OHC) dysfunction to the total audiometric loss in a sample o...

journal_title：Frontiers in neuroscience

authors： Johannesen PT,Pérez-González P,Lopez-Poveda EA

更新日期：2014-07-23 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is a lethal X-linked muscular disease caused by defective expression of the cytoskeletal protein dystrophin (Dp427). Selected autonomic and central neurons, including retinal neurons, express Dp427 and/or dystrophin shorter isoforms. Because of this, DMD patients may also experience d...

journal_title：Frontiers in neuroscience

authors： Persiconi I,Cosmi F,Guadagno NA,Lupo G,De Stefano ME

更新日期：2020-08-31 00:00:00

abstract：:Central pattern generator (CPG) networks coordinate the generation of rhythmic activity such as locomotion and respiration. Their development is driven by various transcription factors, one of which is the Wilms tumor protein (Wt1). It is present in dI6 neurons of the mouse spinal cord, and involved in the coordinatio...

journal_title：Frontiers in neuroscience

authors： Schnerwitzki D,Hayn C,Perner B,Englert C

更新日期：2020-11-30 00:00:00

abstract：:Wireless electroencephalography (EEG) of small animal subjects typically utilizes miniaturized EEG devices which require a robust recording and electrode assembly that remains in place while also being well-tolerated by the animal so as not to impair the ability of the animal to perform normal living activities or exp...

journal_title：Frontiers in neuroscience

authors： Vogler EC,Flynn DT,Busciglio F,Bohannan RC,Tran A,Mahavongtrakul M,Busciglio JA

更新日期：2017-11-14 00:00:00

abstract：:Accumulation of misfolded proteins results in cellular stress, and is detected by specific sensors in the endoplasmic reticulum, collectively known as the unfolded protein response (UPR). It has been prominently proposed that the UPR is involved in the pathophysiology of Parkinson's disease (PD). In the present study,...

journal_title：Frontiers in neuroscience

authors： Baek JH,Mamula D,Tingstam B,Pereira M,He Y,Svenningsson P

更新日期：2019-07-05 00:00:00

abstract：:Recent increases in attention deficit hyperactivity disorder (ADHD) diagnoses, and the escalation of stimulant prescriptions, has raised concern about diversion and abuse of stimulants, as well as the ethics of using these drugs as "cognitive enhancers."Such concern appears misplaced in the face of substantial evidenc...

journal_title：Frontiers in neuroscience

authors： Advokat C,Scheithauer M

更新日期：2013-05-29 00:00:00

abstract：:Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominant form of HSP, and ...

journal_title：Frontiers in neuroscience

authors： Napoli B,Gumeni S,Forgiarini A,Fantin M,De Filippis C,Panzeri E,Vantaggiato C,Orso G

更新日期：2019-11-19 00:00:00

abstract：:Neural stem cells-based therapies have shown great potential for central nervous system regeneration, with three-dimensional (3D) culture systems representing a key technique for tissue engineering applications, as well as disease modeling and drug screenings. Self-assembling peptides (SAPs), providing biomimetic synt...

journal_title：Frontiers in neuroscience

authors： Marchini A,Favoino C,Gelain F

更新日期：2020-05-05 00:00:00

abstract：:Perinatal asphyxia (PA) is a clinical condition brought by a birth temporary oxygen deprivation associated with long-term damage in the corpus striatum, one of the most compromised brain areas. Palmitoylethanolamide (PEA) is a neuromodulator well known for its protective effects in brain injury models, including PA, a...

journal_title：Frontiers in neuroscience

authors： Udovin LD,Kobiec T,Herrera MI,Toro-Urrego N,Kusnier CF,Kölliker-Frers RA,Ramos-Hryb AB,Luaces JP,Otero-Losada M,Capani F

更新日期：2020-01-08 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development and synaptic plasticity that is fundamental to neural circuit formation and cognition. It is also involved in the control of appetite and body weight, with mutations in the genes for BDNF and its receptor, TrkB, resulting in remarka...

journal_title：Frontiers in neuroscience

authors： Vanevski F,Xu B

更新日期：2013-03-21 00:00:00

abstract：:The functional characterization of crustacean neuropeptides and their cognate receptors has not kept pace with the recent advances in sequence determination and, therefore, our understanding of the physiological roles of neuropeptides in this important arthropod sub-phylum is rather limited. We identified a candidate ...

journal_title：Frontiers in neuroscience

authors： Alexander J,Oliphant A,Wilcockson DC,Webster SG

更新日期：2018-07-04 00:00:00

abstract：:Background: Stress-induced cellular changes in limbic brain structures contribute to the development of various psychopathologies. In vivo detection of these microstructural changes may help us to develop objective biomarkers for psychiatric disorders. Diffusion tensor imaging (DTI) is an advanced neuroimaging techniq...

journal_title：Frontiers in neuroscience

authors： Nagy SA,Vranesics A,Varga Z,Csabai D,Bruszt N,Bali ZK,Perlaki G,Hernádi I,Berente Z,Miseta A,Dóczi T,Czéh B

更新日期：2020-06-03 00:00:00

abstract：:The cocaine- and amphetamine-regulated transcript (CART) has been the subject of significant interest for over a decade. Work to decipher the detailed mechanism of CART function has been hampered by the lack of specific pharmacological tools like antagonists and the absence of a specific CART receptor(s). However, ext...

journal_title：Frontiers in neuroscience

authors： Lau J,Herzog H

更新日期：2014-10-13 00:00:00

abstract：:Posterior parietal cortex is frequently activated during episodic memory retrieval but its role during retrieval and its interactions with the hippocampus are not yet clear. In this fMRI study, we investigated the neural bases of recognition memory when study repetitions and retrieval goals were manipulated. During en...

journal_title：Frontiers in neuroscience

authors： Ciaramelli E,Burianová H,Vallesi A,Cabeza R,Moscovitch M

更新日期：2020-11-03 00:00:00

abstract：:Previous studies suggested that both robot-assisted rehabilitation and non-invasive brain stimulation can produce a slight improvement in severe chronic stroke patients. It is still unknown whether their combination can produce synergistic and more consistent improvements. Safety and efficacy of this combination has b...

journal_title：Frontiers in neuroscience

authors： Di Lazzaro V,Capone F,Di Pino G,Pellegrino G,Florio L,Zollo L,Simonetti D,Ranieri F,Brunelli N,Corbetto M,Miccinilli S,Bravi M,Milighetti S,Guglielmelli E,Sterzi S

更新日期：2016-03-08 00:00:00

abstract：:It has long been suggested that sound plays a role in the postural control process. Few studies however have explored sound and posture interactions. The present paper focuses on the specific impact of audition on posture, seeking to determine the attributes of sound that may be useful for postural purposes. We invest...

journal_title：Frontiers in neuroscience

authors： Gandemer L,Parseihian G,Kronland-Martinet R,Bourdin C

更新日期：2017-06-26 00:00:00

abstract：:The brain is the most complex organ in the body, controlling our highest functions, as well as regulating myriad processes which incorporate the entire physiological system. The effects of prospective therapeutic entities on the brain and central nervous system (CNS) may potentially cause significant injury, hence, CN...

journal_title：Frontiers in neuroscience

authors： Grainger AI,King MC,Nagel DA,Parri HR,Coleman MD,Hill EJ

更新日期：2018-08-31 00:00:00

abstract：:Up to 50% of traumatic brain injury (TBI) survivors demonstrate persisting and late-onset anxiety disorders indicative of limbic system dysregulation, yet the pathophysiology underlying the symptoms is unclear. We hypothesize that the development of TBI-induced anxiety-like behavior in an experimental model of TBI is ...

journal_title：Frontiers in neuroscience

authors： Beitchman JA,Griffiths DR,Hur Y,Ogle SB,Bromberg CE,Morrison HW,Lifshitz J,Adelson PD,Thomas TC

更新日期：2020-01-21 00:00:00

abstract：:Gene editing is an attractive potential treatment of inherited retinopathies. However, it often relies on endogenous DNA repair. Retinal DNA repair is incompletely characterized in humans and animal models. We investigated recruitment of the double stranded break (DSB) repair complex of γH2AX and 53bp1 in both develop...

journal_title：Frontiers in neuroscience

authors： Müller B,Ellinwood NM,Lorenz B,Stieger K

更新日期：2018-05-01 00:00:00

abstract：:The present study interrogated a quantitative trait locus (QTL) on Chr 4 associated with the population sizes of two types of bipolar cell in the mouse retina. This locus was identified by quantifying the number of rod bipolar cells and Type 2 cone bipolar cells across a panel of recombinant inbred (RI) strains of mic...

journal_title：Frontiers in neuroscience

authors： Kautzman AG,Keeley PW,Ackley CR,Leong S,Whitney IE,Reese BE

更新日期：2018-12-03 00:00:00

abstract：:The enteric glia, a neural crest-derived cell type that composes the Enteric Nervous System, is involved in controlling gut functions, including motility, gut permeability, and neuronal communication. Moreover this glial cell could to give rise to new neurons. It is believed that enteric neurons are generated up to 21...

journal_title：Frontiers in neuroscience

authors： Veríssimo CP,Carvalho JDS,da Silva FJM,Campanati L,Moura-Neto V,Coelho-Aguiar JM

更新日期：2019-09-03 00:00:00

abstract：:Metabolic confusion has been linked to the pathogenesis of Parkinson's disease (PD), while the dynamic changes associated with the onset and progression of PD remain unclear. Herein, dynamic changes in metabolites were detected from the initiation to the development of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

journal_title：Frontiers in neuroscience

authors： Lu Y,Zhang X,Zhao L,Yang C,Pan L,Li C,Liu K,Bai G,Gao H,Yan Z

更新日期：2018-02-20 00:00:00

abstract：:State-of-the-art large-scale neuromorphic systems require sophisticated spike event communication between units of the neural network. We present a high-speed communication infrastructure for a waferscale neuromorphic system, based on application-specific neuromorphic communication ICs in an field programmable gate ar...

journal_title：Frontiers in neuroscience

authors： Scholze S,Schiefer S,Partzsch J,Hartmann S,Mayr CG,Höppner S,Eisenreich H,Henker S,Vogginger B,Schüffny R

更新日期：2011-10-12 00:00:00

abstract：:Increasingly, neuroimaging researchers are exploring the use of real-time functional magnetic resonance imaging (rt-fMRI) as a way to access a participant's ongoing brain function throughout a scan. This approach presents novel and exciting experimental applications ranging from monitoring data quality in real time, t...

journal_title：Frontiers in neuroscience

authors： MacInnes JJ,Adcock RA,Stocco A,Prat CS,Rao RPN,Dickerson KC

更新日期：2020-09-15 00:00:00

abstract：Purpose:The study is conducted to identify the best corpus callosum (CC) sub-region that corresponds to highest callosal tissue alteration occurred due to Parkinsonism. In this regard the efficacy of local binary pattern (LBP) based texture analysis (TA) of CC is performed to quantify the changes in topographical distr...

journal_title：Frontiers in neuroscience

authors： Bhattacharya D,Sinha N,Prasad S,Pal PK,Saini J,Mangalore S

更新日期：2020-05-28 00:00:00

abstract：:Recent non-invasive brain stimulation techniques in combination with motor training can enhance neuroplasticity and learning. It is reasonable to assume that such neuroplasticity-based interventions constitute a useful rehabilitative tool for patients with Parkinson's Disease (PD). Regarding motor skill training, many...

journal_title：Frontiers in neuroscience

authors： Horiba M,Ueki Y,Nojima I,Shimizu Y,Sahashi K,Itamoto S,Suzuki A,Yamada G,Matsukawa N,Wada I

更新日期：2019-06-19 00:00:00

abstract：:Introduction: Spasticity is a typical motor disorder in patients affected by stroke. Typically post-stroke rehabilitation consists of repetition of mobilization exercises on impaired limbs, aimed to reduce muscle hypertonia and mitigate spastic reflexes. It is currently strongly debated if the treatment's effectivenes...

journal_title：Frontiers in neuroscience

authors： Crea S,Cempini M,Mazzoleni S,Carrozza MC,Posteraro F,Vitiello N

更新日期：2017-05-12 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) allows studying human brain function non-invasively up to the spatial resolution of cortical columns and layers. Most fMRI acquisitions rely on the blood oxygenation level dependent (BOLD) contrast employing T(*) 2 weighted 2D multi-slice echo-planar imaging (EPI). At ultra...

journal_title：Frontiers in neuroscience

authors： Kemper VG,De Martino F,Vu AT,Poser BA,Feinberg DA,Goebel R,Yacoub E

更新日期：2015-05-05 00:00:00

abstract：:Transcutaneous vagus nerve stimulation (tVNS) is widely used for clinical applications, but its mechanism of action is poorly understood. One candidate pathway that might mediate the effects of tVNS is an increase in GABAergic neurotransmission. In this study, we investigated the effect of tVNS on visual bistable perc...

journal_title：Frontiers in neuroscience

authors： Keute M,Boehrer L,Ruhnau P,Heinze HJ,Zaehle T

更新日期：2019-03-08 00:00:00

abstract：:Background: Tourette Syndrome (TS) is a neurodevelopmental disorder with childhood-onset, with a typical decline in tic severity, as well as an increasing ability to suppress tics in late childhood and adolescence. These processes develop in parallel with general improvement of self-regulatory abilities, and performan...

journal_title：Frontiers in neuroscience

authors： Eichele H,Eichele T,Marquardt L,Adolfsdottir S,Hugdahl K,Sørensen L,Plessen KJ

更新日期：2017-06-12 00:00:00