Fractional Stability of Trunk Acceleration Dynamics of Daily-Life Walking: Toward a Unified Concept of Gait Stability.

abstract：:Human pluripotent stem cells (hPSCs) represent a new and exciting field in modern medicine, now the focus of many researchers and media outlets. The hype is well-earned because of the potential of stem cells to contribute to disease modeling, drug screening, and even therapeutic approaches. In this review, we focus fi...

journal_title：Frontiers in physiology

authors： Martinez Y,Dubois-Dauphin M,Krause KH

更新日期：2012-03-19 00:00:00

abstract：Background:The underlying mechanisms by which diabetes and dyslipidemia contribute to diabetic nephropathy (DN) are not fully understood. In this study, we aimed to investigate the role of high glucose (HG) on intracellular cholesterol accumulation in glomerular endothelial cells (GEnCs) and its potential mechanism. M...

journal_title：Frontiers in physiology

authors： Wang Y,Xiao S,Zhou S,Zhang R,Liu H,Lin Y,Yu P

更新日期：2020-10-19 00:00:00

abstract：:Submaximal vertical hopping capitalizes on the strain energy storage-recovery mechanism associated with the stretch-shortening cycle and is emerging as an important component of progressive rehabilitation protocols in Achilles tendon injury and a determinant of readiness to return to sport. This study explored the rel...

journal_title：Frontiers in physiology

authors： Wearing SC,Kuhn L,Pohl T,Horstmann T,Brauner T

更新日期：2020-12-03 00:00:00

abstract：:This work investigates the effect of arterial bifurcation angulation on atherosclerosis development through in-silico simulations of coupled cell dynamics. The computational model presented here combines cellular pathways, fluid dynamics, and physiologically-realistic vessel geometries as observed in the human vascula...

journal_title：Frontiers in physiology

authors： Dowding S,Zakkaroff C,Moore S,David T

更新日期：2018-10-31 00:00:00

abstract：:This study was designed to investigate the effects of a newly synthesized carboxymethyl-glucan (CM-G) on blood pressure (BP), baroreflex sensitivity (BRS) and sympathetic vascular modulation in renovascular hypertensive rats. Male Wistar rats were divided into four groups: Sham (n = 10); 2K1C (subjected to renal arter...

journal_title：Frontiers in physiology

authors： Carvalho-Galvão A,Gadelha DDA,de Brito Alves JL,Khan BA,Castro-Gomez RJH,Cruz JC,Magnani M,Braga VA

更新日期：2018-05-23 00:00:00

abstract：:The earliest humans relied on large quantities of metabolic energy from the oxidation of fatty acids to develop larger brains and bodies, prevent and reduce disease risk, extend longevity, in addition to other benefits. This was enabled through the consumption of a high fat and low-carbohydrate diet (LCD). Increased f...

journal_title：Frontiers in physiology

authors： Maffetone P,Laursen PB

更新日期：2020-04-02 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2020.00302.]. ...

journal_title：Frontiers in physiology

authors： Semple C,Riveros D,Nagy JA,Rutkove SB,Mortreux M

更新日期：2020-07-03 00:00:00

abstract：:Aim: Combined use of herbal medicines in patients underwent dual antiplatelet therapy (DAPT) might cause bleeding or thrombosis because herbal medicines with anti-platelet activities may exhibit interactions with DAPT. In this study, we tried to use a feedback system control (FSC) optimization technique to optimize do...

journal_title：Frontiers in physiology

authors： Liu W,Li YL,Feng MT,Zhao YW,Ding X,He B,Liu X

更新日期：2018-05-04 00:00:00

abstract：:Microvesicles (MVs) are released by most cell types in physiological conditions, but their number is often increased upon cellular activation or neoplastic transformation. This suggests that their detection may be helpful in pathological conditions to have information on activated cell types and, possibly, on the natu...

journal_title：Frontiers in physiology

authors： Colombo E,Borgiani B,Verderio C,Furlan R

更新日期：2012-03-29 00:00:00

abstract：:The epidemics of obesity and diabetes mellitus are associated with an increased incidence of both atrial fibrillation (AF), the most common sustained arrhythmia in adults, and sudden cardiac death (SCD). Obesity and DM are known to have adverse effects on cardiac structure and function. The pathologic mechanisms are t...

journal_title：Frontiers in physiology

authors： Homan EA,Reyes MV,Hickey KT,Morrow JP

更新日期：2019-01-07 00:00:00

abstract：:Recent concerns over the impact of antidepressant medications, including the selective serotonin reuptake inhibitors (SSRIs), on cardiovascular function highlight the importance of research on the moderating effects of specific lifestyle factors such as physical activity. Studies in affective neuroscience have demonst...

journal_title：Frontiers in physiology

authors： Hanson CS,Outhred T,Brunoni AR,Malhi GS,Kemp AH

更新日期：2013-09-24 00:00:00

abstract：:Mild normobaric hypoxia (NH) and modest exercise have multiple beneficial effects on health, but the changes in physiological function induced by NH and/or exercise remain unclear. The purpose of this investigation was to examine the specific effects of NH and/or exercise on cardiac function and myocardial structure a...

journal_title：Frontiers in physiology

authors： Li QF,Wang H,Zheng L,Yang F,Li HZ,Li JX,Cheng D,Lu K,Liu Y

更新日期：2020-01-21 00:00:00

abstract：:Highly aerobically trained individuals are unable to achieve maximal oxygen uptake ([Formula: see text]) during exhaustive running lasting ~2 min, instead [Formula: see text] plateaus below [Formula: see text] after ~1 min. Hypoxia offers the opportunity to study the ([Formula: see text]) response to an exhaustive run...

journal_title：Frontiers in physiology

authors： Black MI,Potter CR,Corbett J,Clark CC,Draper SB

更新日期：2017-02-21 00:00:00

abstract：:The mouse is one of the most important model organisms for understanding human genetic function and disease. This includes characterization of the factors that influence energy expenditure and dysregulation of energy balance leading to obesity and its sequelae. Measuring energy metabolism in the mouse presents a chall...

journal_title：Frontiers in physiology

authors： Speakman JR

更新日期：2013-03-14 00:00:00

abstract：:Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, play an important role in cellular communication during skeletal growth and homeostasis. Bioactive molecules carried by EVs are transported to neighboring and distant cells to trigger a series of signaling cascades influencing bone ...

journal_title：Frontiers in physiology

authors： Yuan FL,Wu QY,Miao ZN,Xu MH,Xu RS,Jiang DL,Ye JX,Chen FH,Zhao MD,Wang HJ,Li X

更新日期：2018-05-30 00:00:00

abstract：:Hemoglobin (Hb) continuously undergoes autoxidation producing superoxide which dismutates into hydrogen peroxide (H2O2) and is a potential source for subsequent oxidative reactions. Autoxidation is most pronounced under hypoxic conditions in the microcirculation and for unstable dimers formed at reduced Hb concentrati...

journal_title：Frontiers in physiology

authors： Rifkind JM,Mohanty JG,Nagababu E

更新日期：2015-01-14 00:00:00

abstract：:Patients undergoing the complex treatment for hematological malignancies are exposed to a high physiological and psychological distress inducing fatigue and physical inactivity. In line with cancer-related metabolic changes patients are predisposed for skeletal muscle mass loss that leads to a functional decline, affe...

journal_title：Frontiers in physiology

authors： Schink K,Reljic D,Herrmann HJ,Meyer J,Mackensen A,Neurath MF,Zopf Y

更新日期：2018-12-18 00:00:00

abstract：:Pulpitis in primary teeth, a condition caused by presence of bacteria, is highly prevalent worldwide. The use of biocompatibility materials with anti-inflammatory, anti-bacterial, and regenerative properties is critical for prognosis of this endodontic disease. This study aimed to identify expression of human β defens...

journal_title：Frontiers in physiology

authors： Zhai Y,Wang Y,Rao N,Li J,Li X,Fang T,Zhao Y,Ge L

更新日期：2019-10-22 00:00:00

abstract：:Extracellular vesicles (EVs) - including exosomes, microvesicles and apoptotic bodies - have received much scientific attention last decade as mediators of a newly discovered cell-to-cell communication system, acting at short and long distances. EVs carry biologically active molecules, thus providing signals that infl...

journal_title：Frontiers in physiology

authors： Rackov G,Garcia-Romero N,Esteban-Rubio S,Carrión-Navarro J,Belda-Iniesta C,Ayuso-Sacido A

更新日期：2018-06-05 00:00:00

abstract：:Survivors of cerebral aneurysm rupture are at risk for significant morbidity and neurological deficits. Much of this is related to the effects of blood in the subarachnoid space which induces an inflammatory cascade with numerous downstream consequences. Recent clinical trials have not been able to reduce the toxic ef...

journal_title：Frontiers in physiology

authors： Blackburn SL,Kumar PT,McBride D,Zeineddine HA,Leclerc J,Choi HA,Dash PK,Grotta J,Aronowski J,Cardenas JC,Doré S

更新日期：2018-05-31 00:00:00

abstract：:[This corrects the article on p. 354 in vol. 10, PMID: 30984032.]. ...

journal_title：Frontiers in physiology

authors： Clos P,Laroche D,Stapley PJ,Lepers R

更新日期：2020-08-12 00:00:00

abstract：:Circadian rhythms are essential for health and regulate various physiological functions. These rhythms are regulated by a negative-feedback loop involving clock genes in the suprachiasmatic nucleus (SCN) and peripheral tissues. The rate of secretion of salivary substances, ions, and water follows a circadian rhythm, h...

journal_title：Frontiers in physiology

authors： Satou R,Sato M,Kimura M,Ishizuka Y,Tazaki M,Sugihara N,Shibukawa Y

更新日期：2017-05-23 00:00:00

abstract：:The main objective of this study was to investigate the effects of the order of physical exercises on body composition, physical fitness, and cardiometabolic risk in adolescents participating in an interdisciplinary program focusing on the treatment of obesity. The final 12-week analyses involved 33 female adolescents...

journal_title：Frontiers in physiology

authors： Branco BHM,Valladares D,de Oliveira FM,Carvalho IZ,Marques DC,Coelho AA,de Oliveira LP,Bertolini SMMG

更新日期：2019-08-06 00:00:00

abstract：:Skeletal muscles are large cells with multiple nuclei that are precisely positioned. The importance of the correct nuclear position is highlighted by the correlation between mispositioned nuclei and muscle disease (Spiro et al., 1966; Gueneau et al., 2009). Myonuclei are generally considered to be equivalent and there...

journal_title：Frontiers in physiology

authors： Perillo M,Folker ES

更新日期：2018-11-01 00:00:00

abstract：:The mealworm beetle, Tenebrio molitor, is currently considered as a pest when infesting stored grains or grain products. However, mealworms are now being promoted as a beneficial insect because their high nutrient content makes them a viable food source and because they are capable of degrading polystyrene and plastic...

journal_title：Frontiers in physiology

authors： Vigneron A,Jehan C,Rigaud T,Moret Y

更新日期：2019-03-12 00:00:00

abstract：:Recently, two alternative targets in insect periphery nerve system have been explored for environmentally-friendly approaches in insect pest management, namely odorant-binding proteins (OBPs) and odorant receptors (ORs). Located in insect antennae, OBPs are thought to be involved in the transport of odorants to ORs fo...

journal_title：Frontiers in physiology

authors： Venthur H,Zhou JJ

更新日期：2018-08-24 00:00:00

abstract：:Previous studies reported enhanced cerebrovascular CO2 reactivity upon ascent to high altitude using linear models. However, there is evidence that this response may be sigmoidal in nature. Moreover, it was speculated that these changes at high altitude are mediated by alterations in acid-base buffering. Accordingly, ...

journal_title：Frontiers in physiology

authors： Fan JL,Subudhi AW,Duffin J,Lovering AT,Roach RC,Kayser B

更新日期：2016-01-08 00:00:00

abstract：:The vascular endothelium supplying the brain exhibits very low paracellular and transcellular permeability and is a major constituent of the blood-brain barrier. High-density lipoprotein (HDL) crosses the blood-brain barrier by transcytosis, but technical limitations have made it difficult to elucidate its regulation....

journal_title：Frontiers in physiology

authors： Fung KY,Wang C,Nyegaard S,Heit B,Fairn GD,Lee WL

更新日期：2017-10-30 00:00:00

abstract：:Fatigue is one of the most debilitating symptoms of multiple sclerosis (MS), and the underlying mechanisms are poorly understood. When exposed to a physical or cognitive challenge, individuals with MS tend to exhibit greater declines in task performance (performance fatigability) and increased levels of self-reported ...

journal_title：Frontiers in physiology

authors： Gould JR,Reineberg AE,Cleland BT,Knoblauch KE,Clinton GK,Banich MT,Corboy JR,Enoka RM

更新日期：2018-10-17 00:00:00

abstract：:Trehalases (treh) have been found in different organisms, such as bacteria, fungi, yeast, nematodes, insects, vertebrates, and plants. Their biochemical properties are extremely variable and not yet fully understood. Gene expression patterns have shown differences among insect species suggesting a potential functional...

journal_title：Frontiers in physiology

authors： Nardelli A,Vecchi M,Mandrioli M,Manicardi GC

更新日期：2019-02-15 00:00:00