Novel Psychoactive Substances-Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs.

abstract：:Cognitive impairment is an important aspect of schizophrenia, where cognitive remediation therapy (CRT) is a promising treatment for improving cognitive functioning. While neurobiological dysfunction in schizophrenia has been the target of much research, the neural substrate of cognitive remediation and recovery has n...

journal_title：Frontiers in psychiatry

authors： Thorsen AL,Johansson K,Løberg EM

更新日期：2014-08-15 00:00:00

abstract：:Objective: We previously found that chronic ketamine usages were associated with various psychotic and cognitive symptoms mimicking schizophrenia. The blockade of the NMDA receptor and subsequent nitric oxide synthase 1 (NOS1) dysfunction were found to be closely correlated with schizophrenia including NOS1 gene polym...

journal_title：Frontiers in psychiatry

authors： Chen J,Zhang M,Zhou C,Ding Y,Fan N,He H

更新日期：2020-12-23 00:00:00

abstract：:Despite many studies documenting the prevalence of various co-occurring psychiatric symptoms in children and adults with ASD, less is known about how these symptoms relate to subtypes defined by particular phenotypic features within the ASD population. We examined the severity and prevalence of comorbid symptoms of ps...

journal_title：Frontiers in psychiatry

authors： Plesa Skwerer D,Joseph RM,Eggleston B,Meyer SR,Tager-Flusberg H

更新日期：2019-02-18 00:00:00

abstract：:This paper presents the first systematic case-control study of correlates of mass psychogenic illness (MPI) in an adolescent school population. MPI is generally construed as a dissociative phenomenon spread by social contagion to individuals who are prone to dissociation. We sought to test if the correlates of dissoci...

journal_title：Frontiers in psychiatry

authors： Sapkota RP,Brunet A,Kirmayer LJ

更新日期：2020-11-17 00:00:00

abstract：:Introduction: Vitamin D inadequacy or deficiency (VDID) has been reported in a high percentage of otherwise healthy individuals. Factors that may contribute to the high prevalence of VDID in people with mental disorders include diet low in vitamin D, poor sunlight exposure, decrease in cutaneous vitamin D synthesis, i...

journal_title：Frontiers in psychiatry

authors： Cuomo A,Maina G,Bolognesi S,Rosso G,Beccarini Crescenzi B,Zanobini F,Goracci A,Facchi E,Favaretto E,Baldini I,Santucci A,Fagiolini A

更新日期：2019-03-29 00:00:00

abstract：:Anhedonia is a condition in which the capacity of experiencing pleasure is totally or partially lost, and it refers to both a state symptom in various psychiatric disorders and a personality trait. It has a putative neural substrate, originating in the dopaminergic mesolimbic and mesocortical reward circuit. Anhedonia...

journal_title：Frontiers in psychiatry

authors： Hatzigiakoumis DS,Martinotti G,Giannantonio MD,Janiri L

更新日期：2011-03-17 00:00:00

abstract：BACKGROUND:The project "Quality Assurance in Ambulatory Psychotherapy in Bavaria" (QS-PSY-BAY) focuses on the quality assurance of outpatient psychotherapy (OPT) in Germany in terms of symptom reduction and cost reduction under naturalistic conditions. In this study, we examined the effectiveness of psychotherapy in te...

journal_title：Frontiers in psychiatry

authors： Altmann U,Zimmermann A,Kirchmann HA,Kramer D,Fembacher A,Bruckmayer E,Pfaffinger I,von Heymann F,Auch E,Steyer R,Strauss BM

更新日期：2016-06-13 00:00:00

abstract：:Background: People with severe mental illness have difficulties finding and maintaining competitive employment. This is particularly so for those living in supported housing who, by definition, have significant day-to-day support needs: in the Netherlands only 3 to 5% of people with serious mental health problems who ...

journal_title：Frontiers in psychiatry

authors： Roeg D,de Winter L,Bergmans C,Couwenbergh C,McPherson P,Killaspy H,van Weeghel J

更新日期：2021-01-14 00:00:00

abstract：:The present study aims to analyze the clinical and socio-demographic characteristics of patients with obsessive-compulsive disorder (OCD) in comorbidity with schizotypal personality disorder (SPD), as well as the response rate to pharmacological treatments. OCD+SPD patients had a younger age at onset, a higher probabi...

journal_title：Frontiers in psychiatry

authors： Perris F,Fabrazzo M,De Santis V,Luciano M,Sampogna G,Fiorillo A,Catapano F

更新日期：2019-06-17 00:00:00

abstract：:Prenatal infections have been linked to the development of schizophrenia (SCZ) and other neurodevelopmental disorders in the offspring, and work in animal models indicates that this is to occur through the maternal inflammatory response triggered by infection. Several studies in animal models demonstrated that acute i...

journal_title：Frontiers in psychiatry

authors： Aguilar-Valles A,Rodrigue B,Matta-Camacho E

更新日期：2020-08-21 00:00:00

abstract：BACKGROUND:Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting children, adolescents, and adults. Its etiology is not well understood, but it is increasingly believed to result from diverse pathophysiologies that affect the structure and function of specific brain circui...

journal_title：Frontiers in psychiatry

authors： Khadka S,Pearlson GD,Calhoun VD,Liu J,Gelernter J,Bessette KL,Stevens MC

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Females are twice as likely as males to experience depression. Recent findings indicate a relationship linking inflammation with depression. Whether the higher prevalence of depression in women is sex-specific or if inflammation contributes to a higher prevalence of depression in females is unclear. Thus, th...

journal_title：Frontiers in psychiatry

authors： Birur B,Amrock EM,Shelton RC,Li L

更新日期：2017-06-16 00:00:00

abstract：:Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have exa...

journal_title：Frontiers in psychiatry

authors： Cheung SG,Goldenthal AR,Uhlemann AC,Mann JJ,Miller JM,Sublette ME

更新日期：2019-02-11 00:00:00

abstract：:Throughout the world, drug and alcohol use has a clear adolescent onset (Degenhardt et al., 2008). Alcohol continues to be the most popular drug among teens and emerging adults, with almost a third of 12th graders and 40% of college students reporting recent binge drinking (Johnston et al., 2009, 2010), and marijuana ...

journal_title：Frontiers in psychiatry

authors： Lisdahl KM,Gilbart ER,Wright NE,Shollenbarger S

更新日期：2013-07-01 00:00:00

abstract：:About 15% of mothers suffer from postpartum psychiatric disorders, such as depression, anxiety, or psychosis. Numerous studies have shown maternal caregiving behavior to be negatively affected under these circumstances. The current study sets out to shed light on specific caregiving behaviors of affected mothers in th...

journal_title：Frontiers in psychiatry

authors： Heinisch C,Galeris MG,Gabler S,Simen S,Junge-Hoffmeister J,Fößel J,Spangler G

更新日期：2019-07-22 00:00:00

abstract：Background:Brain-derived Neurotrophic Factor (BDNF) is considered the main cerebral neurotrophin and is produced in the central neural system and peripherals. Its levels are reduced in patients with several psychiatric disorders, but it is unclear if the response to psychotherapy can alter its concentration. Objective...

journal_title：Frontiers in psychiatry

authors： Claudino FCA,Gonçalves L,Schuch FB,Martins HRS,da Rocha NS

更新日期：2020-05-19 00:00:00

abstract：:The human gut microbiome is emerging as a key modulator of homeostasis, with far-reaching implications for various multifactorial diseases, including anorexia nervosa (AN). Despite significant morbidity and mortality, the underlying mechanisms of this eating disorder are poorly understood, but the classical view defin...

journal_title：Frontiers in psychiatry

authors： Ghenciulescu A,Park RJ,Burnet PWJ

更新日期：2021-01-12 00:00:00

abstract：:Pharmacogenomics represents a potentially powerful enhancement to the current standard of care for psychiatric patients. However, a variety of biological and technical challenges must be addressed in order to provide adequate clinical decision support for personalized prescribing and dosing based on genomic data. This...

journal_title：Frontiers in psychiatry

authors： Jarvis JP,Peter AP,Shaman JA

更新日期：2019-06-20 00:00:00

abstract：:Background: Job burnout has become an increasing prevailing phenomenon among nurses in both developed and developing countries. There is a paucity of research exploring the relationship between perceived stress (i.e., the level of one's perception or appraisal of stress rather than objective stressful events) and job ...

journal_title：Frontiers in psychiatry

authors： Song Y,Yang F,Sznajder K,Yang X

更新日期：2020-11-13 00:00:00

abstract：:Suicide is the most severe consequence of depression which has become a leading cause of disability and a global disease burden. Recent evidence indicates a central role of small molecules in the pathogenesis of depression and associated suicidal behaviors. However, there lacks a systemic exploration of small molecule...

journal_title：Frontiers in psychiatry

authors： Liu S

更新日期：2020-04-16 00:00:00

abstract：:This study investigated biases for negative-positive information in component processes of visual attention (initial shift vs. maintenance of gaze) among women in late pregnancy with or without depressive symptoms. Eye movements were recorded while participants viewed a series of picture pairs depicting negative, posi...

journal_title：Frontiers in psychiatry

authors： Tang W,Bao C,Xu L,Zhu J,Feng W,Zhang W,Lin C,Chen L,Cheng Q,Ding P,Zhou M,Bao Y,Yu X,Zhao K,He J

更新日期：2019-10-31 00:00:00

abstract：:Post-stroke depression (PSD) is one of the most frequent complications of stroke. The Yi-nao-jie-yu prescription (YNJYP) is an herbal prescription widely used as a therapeutic agent against PSD in traditional Chinese medicine. Disruption of adult neurogenesis has attracted attention as a potential cause of cognitive p...

journal_title：Frontiers in psychiatry

authors： Tian H,Li X,Tang Q,Zhang W,Li Q,Sun X,Zhao R,Ma C,Liu H,Gao Y,Han F

更新日期：2018-10-16 00:00:00

abstract：:Background: Developmental disabilities are defined by delays in learning, language, and behavior, yet growing evidence has revealed disturbances in metabolic systems that may also be present. Little is known about whether these metabolic issues contribute to the symptoms or severity of these disabilities, or whether s...

journal_title：Frontiers in psychiatry

authors： Sotelo-Orozco J,Abbeduto L,Hertz-Picciotto I,Slupsky CM

更新日期：2020-12-22 00:00:00

abstract：:Introduction: Chronic recreational methamphetamine use causes dopaminergic neurotoxicity, which has been linked to impairments in executive functioning. Within this functional domain, response selection and the resolution of associated conflicts have repeatedly been demonstrated to be strongly modulated by dopamine. Y...

journal_title：Frontiers in psychiatry

authors： Bensmann W,Ernst J,Rädle M,Opitz A,Beste C,Stock AK

更新日期：2019-11-19 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (∼1.5 h) smokers. The aim of this study was to assess whether tDCS modulates ...

journal_title：Frontiers in psychiatry

authors： Xu J,Fregni F,Brody AL,Rahman AS

更新日期：2013-09-20 00:00:00

abstract：:Research has demonstrated the short- and long-term impacts of maternal mental health and well-being on children's emotional and behavioral outcomes. It is thus important to better understand the antecedents of maternal depression and stress. The aim of this study was to determine whether the contribution of perceived ...

journal_title：Frontiers in psychiatry

authors： deMontigny F,Gervais C,Pierce T,Lavigne G

更新日期：2020-11-02 00:00:00

abstract：:Post-traumatic stress disorder (PTSD) is a heterogeneous disorder that affects individuals exposed to trauma (e.g., combat, interpersonal violence, and natural disasters). It is characterized by hyperarousal, intrusive reminders of the trauma, avoidance of trauma-related cues, and negative cognition and mood. This het...

journal_title：Frontiers in psychiatry

authors： Briscione MA,Jovanovic T,Norrholm SD

更新日期：2014-07-21 00:00:00

abstract：:Background: More information is needed about the efficacy and safety of long-term baclofen in the treatment of alcohol use disorders. The objective of this study was to assess the effect of treatment with tailored-dose baclofen on alcohol consumption in patients with alcohol use disorders followed for 3 years after fi...

journal_title：Frontiers in psychiatry

authors： Pinot J,Rigal L,Granger B,Sidorkiewicz S,Jaury P

更新日期：2018-10-08 00:00:00

abstract：:There is accruing evidence of cerebellar abnormalities in schizophrenia. The theory of cognitive dysmetria considers cerebellar dysfunction a key component of schizophrenia. Delay eyeblink conditioning (EBC), a cerebellar-dependent translational probe, is a behavioral index of cerebellar integrity. The circuitry under...

journal_title：Frontiers in psychiatry

authors： Kent JS,Bolbecker AR,O'Donnell BF,Hetrick WP

更新日期：2015-12-18 00:00:00

abstract：:Excessive glutamate release has been linked to stress and many neurodegenerative diseases. Evidence indicates abnormalities of glutamatergic neurotransmission or glutamatergic dysfunction as playing an important role in the development of many major psychiatric disorders (e.g., schizophrenia, bipolar disorder, and maj...

journal_title：Frontiers in psychiatry

authors： Li CT,Yang KC,Lin WC

更新日期：2019-01-24 00:00:00