Importance of maintaining body weight for prevention of distant metastasis of nasopharyngeal carcinoma: An alternative workflow for cancer-risk assessment.

abstract：:Purpose: We retrospectively collected consecutive survival data of lung adenosquamous cell carcinoma (ASC) patients with brain metastasis (BM) in our institute and discussed the factors related to prognosis of these patients. Patients and Methods: A total of 42 patients diagnosed as lung ASC with BM between July 1, 20...

journal_title：Journal of Cancer

authors： Pan F,Cui S,Wang W,Gu A,Jiang L

更新日期：2018-09-08 00:00:00

abstract：:Colorectal cancer (CRC) is the fifth leading cause of cancer-related death in China. The incidence of Chinese CRC has increased dramatically with the changes of dietary and lifestyle. However, the genetic landscape of Chinese colorectal cancer mutation is still poorly understood. In this study, we have performed whole...

journal_title：Journal of Cancer

authors： Ma R,Jing C,Zhang Y,Cao H,Liu S,Wang Z,Chen D,Zhang J,Wu Y,Wu J,Feng J

更新日期：2020-01-01 00:00:00

abstract：:Cancer-testis (CT) genes played important roles in the progression of malignant tumors and were recognized as promising therapeutic targets. However, the roles of genetic variants in CT genes in lung cancer susceptibility have not been well depicted. This study aimed to evaluate the associations between genetic varian...

journal_title：Journal of Cancer

authors： Li Z,Tang J,Wen W,Wu W,Wang J,Xu J,Yu Y,He Z,Pan X,Wei H,Zhu Y,Hu S,Cao J,Shen H,Que J,Wang W,Zhu Q,Chen L

更新日期：2020-02-03 00:00:00

abstract：:Purpose: The objective of this study was to develop and validate a nomogram for predicting the cancer-specific survival (CSS) in patients with Wilms' tumor (WT). Methods: Patients with WT diagnosed between 2002 and 2015 in the Surveillance, Epidemiology, and End Results (SEER) database were divided randomly into train...

journal_title：Journal of Cancer

authors： Pan Z,You H,Bu Q,Feng X,Zhao F,Li Y,Lyu J

更新日期：2019-08-28 00:00:00

abstract：:We use pulmonary interventional procedures for the diagnosis of pulmonary diseases either for benign or malignant lesions. Flexible bronchoscopy with or without radial endobronchial ultrasound, convex-probe endobronchial ultrasound and electromagnetic navigation are procedures performed in centers with experience in d...

journal_title：Journal of Cancer

authors： Hohenforst-Schmidt W,Zarogoulidis P,Huang H,Man YG,Laskou S,Koulouris C,Giannakidis D,Mantalobas S,Florou MC,Amaniti A,Steinheimer M,Sinha A,Freitag L,Turner JF,Browning R,Vogl T,Roman A,Benhassen N,Kesisoglou I,Sap

更新日期：2018-02-12 00:00:00

abstract：:Cancer is a genetic disease where genetic variations cause abnormally functioning genes that appear to alter expression. Proteins, the final products of gene expression, determine the phenotypes and biological processes. Therefore, detecting gene expression levels can be used for cancer diagnosis, prognosis, and treat...

journal_title：Journal of Cancer

authors： Narrandes S,Xu W

更新日期：2018-06-05 00:00:00

abstract：:Angiogenesis, a highly regulated process, is exploited by tumors like breast cancer to ensure a constant supply of oxygen and nutrients and is key for tumor survival and progression. Estrogen and alcohol independently have been observed to contribute to angiogenesis in breast cancer but their combinatorial effects hav...

journal_title：Journal of Cancer

authors： Maniyar R,Chakraborty S,Suriano R

更新日期：2018-10-06 00:00:00

abstract：PURPOSE:The current study examined quality of life, progression of disease, and survival rate during chemotherapy in newly diagnosed non-small cell lung cancer (NSCLC) patients with depression (n=48) and without depression (n=78). Further, the study explored the hypothesis that the survival benefit resulted from the ch...

journal_title：Journal of Cancer

authors： Chen J,Li W,Cui L,Qian Y,Zhu Y,Gu H,Chen G,Shen Y,Liu Y

更新日期：2015-09-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a major malignancy of cancer-related mortality worldwide. Metastasis-associated in colon cancer-1 (MACC1) was suggested as a marker for vascular invasive HCC. This study investigated the MACC1 single-nucleotide polymorphisms (SNPs) to evaluate HCC susceptibility and clinicopathologica...

journal_title：Journal of Cancer

authors： Lin CH,Hsieh MJ,Lee HL,Yang SF,Su SC,Lee WJ,Chou YE

更新日期：2020-01-14 00:00:00

abstract：:As a crucial event involved in the metastasis and relapse of esophageal cancer, c-Met overexpression has been considered as one of the culprits responsible for the failure in patients who received radiochemotherapy. Since c-Met has been confirmed to be pivotal for cell survival, proliferation and migration, little is ...

journal_title：Journal of Cancer

authors： Chen GZ,Dai WS,Zhu HC,Song HM,Yang X,Wang YD,Min H,Lu Q,Liu S,Sun XC,Zeng XN

更新日期：2017-03-12 00:00:00

abstract：:Background: Infiltration of immune cells and immune microenvironment determine the proliferative activity of the tumor and metastasis. The aim of this study was to analyze the influence of activation or suppression of the immune response mediators on the prognosis of biliary tract cancer (BTC). Methods: We searched Pu...

journal_title：Journal of Cancer

authors： Wang Y,Ding M,Zhang Q,Wang J,Yang X,Zhou F,Li L,Yuan Z,Jin H,Qian Q

更新日期：2017-01-01 00:00:00

abstract：:Pokemon, also known as leukemia/lymphoma-related factor (LRF) is a pro-oncogenic protein highly expressed in several cancers. There have been few in vitro and animal studies about its malignant biological behavior and function, however, its role especially in prostate cancer has not been completely elucidated. Therefo...

journal_title：Journal of Cancer

authors： Jiang F,Zheng Q,Chang L,Li X,Wang X,Gu X

更新日期：2019-04-21 00:00:00

abstract：:Objective: To investigate the development of bronchoscopy in China and compare it with its application in the early 21st century. Methods: The data collection was based on questionnaires. Three hundred and nineteen hospitals, which distributed across 30 provinces and 130 cities, were included in the study. Data about ...

journal_title：Journal of Cancer

authors： Shi D,Li F,Wang K,Kong C,Huang H,Li Q,Jin F,Hu C,Wang C,Shi H,Hu Z,Dong Y,Ning Y,Tsakiridis K,Sapalidis K,Kosmidis C,Vagionas A,Hohenforst-Schmidt W,Freitag L,Turner JF,Drevelegas K,Perdikouri EI,Kovacevic T,

更新日期：2020-07-20 00:00:00

abstract：:Objectives: To investigate the role of inflammation-related factors, lymphocyte-to-monocyte ratio (LMR) alone and combined detection with cancer antigen 125 (CA125), in the prognostic assessment of ovarian cancer (OC). Methods: A retrospective clinicopathologic review was performed. The receiver-operating characterist...

journal_title：Journal of Cancer

authors： Tang Y,Hu HQ,Tang FX,Lin D,Shen R,Deng L,Tang YL,Deng LH,Zhou M,Li J,Su B,Xu F

更新日期：2020-03-04 00:00:00

abstract：:Introduction: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are a standard first-line treatment for advanced EGFR-mutated NSCLC patients. Factors associated with symptoms and quality of life (QOL) improvements have not been investigated. Methods: We conducted a multicenter, prospective study ...

journal_title：Journal of Cancer

authors： Wei YF,Huang WT,Liu TC,Shieh JM,Chian CF,Wu MF,Chang CC,Lin CH,Ko JC,Lin CM,Hsia TC

更新日期：2019-07-10 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is one of the most common types of aggressive cancer. The tumor tissue, which shows an active angiogenesis, is composed of neoplastic and stromal cells, and an abundant inflammatory infiltrate. Angiogenesis is important to support tumor growth, while infiltrating cells contribute to ...

journal_title：Journal of Cancer

authors： Rivas-Fuentes S,Salgado-Aguayo A,Pertuz Belloso S,Gorocica Rosete P,Alvarado-Vásquez N,Aquino-Jarquin G

更新日期：2015-08-07 00:00:00

abstract：:Background: The genetic heterogeneity between primary and metastatic lesions has rarely studied. Purpose: This study aims to compare the mutation profiling of key cancer-related genes in primary lung cancers and their matched lymph nodes (LN) metastasis. Methods: The gene mutation profiling of both primary cancers and...

journal_title：Journal of Cancer

authors： Chen Y,Mao B,Peng X,Zhou Y,Xia K,Guo H,Jiang H,Wang G,Zhuang W

更新日期：2019-03-03 00:00:00

abstract：BACKGROUND:To identify predictors for development of mastoiditis after intensity-modulated radiation therapy (IMRT) in nasopharyngeal carcinoma (NPC). METHODS:Data for 146 NPC patients treated with IMRT was retrospectively reviewed under institutional ethics committee approval. Clinical factors associated with mastoid...

journal_title：Journal of Cancer

authors： Yao JJ,Zhou GQ,Jin YN,Zhang WJ,Lin L,Yu XL,Shao JY,Ma J,Sun Y

更新日期：2016-01-08 00:00:00

abstract：:For many years, the medical treatment of breast cancer was reliant solely on cytotoxic chemotherapy. However, over the past twenty years, treatment has evolved to a more target-directed approach. We now employ tailored therapy based on the presence or absence of receptors for estrogen, progesterone, and human epiderma...

journal_title：Journal of Cancer

authors： Tinoco G,Warsch S,Glück S,Avancha K,Montero AJ

更新日期：2013-01-01 00:00:00

abstract：:Purpose: Systemic therapy has often been used for patients with advanced hepatocellular carcinoma (HCC). However, due to drug resistance, the use of cytotoxic chemotherapy in the treatment of patients with advanced HCC has typically demonstrated low response rates. Secretory clusterin (sCLU) is expressed in aggressive...

journal_title：Journal of Cancer

authors： Wang X,Zou F,Zhong J,Yue L,Wang F,Wei H,Yang G,Jin T,Dong X,Li J,Xiu P

更新日期：2018-04-06 00:00:00

abstract：:Colorectal cancer (CRC) is considered to be closely associated with alteration of intestinal microorganisms. The purpose of present study was to investigate the distribution of gut microbiota in the distinction of microbiota dysbiosis between two disease syndromes called Zheng-Qi-Kui-Xu(ZQKX) and Xie-Du-Yong-Sheng (XD...

journal_title：Journal of Cancer

authors： Wang P,Ding S,Sun L,Feng Y,Guo K,Zhu Y,Huang D,Ruan S

更新日期：2020-10-23 00:00:00

abstract：:Establishing an applicable preclinical model is vital for translational cancer research. Patient-derived xenograft has been important preclinical model systems and widely used for cancer research. Patient-derived xenograft models that represent the tumors of the patients are necessary to better translate research disc...

journal_title：Journal of Cancer

authors： Chen C,Lin W,Huang Y,Chen X,Wang H,Teng L

更新日期：2021-01-01 00:00:00

abstract：:Levels of plasma cell-free DNA (cfDNA) of a large series of children with classical Hodgkin lymphoma (cHL) were evaluated and analyzed at diagnosis and during chemotherapy treatment in relation with clinical characteristics. CfDNA levels in cHL patients were significantly higher compared with controls (p=0.002). CfDNA...

journal_title：Journal of Cancer

authors： Primerano S,Burnelli R,Carraro E,Pillon M,Elia C,Farruggia P,Sala A,Vinti L,Buffardi S,Basso G,Mascarin M,Mussolin L

更新日期：2016-01-12 00:00:00

abstract：:Objective: First, to evaluate the sensitivity and positive predictive value (PPV) of intra-operative frozen section (FS) diagnosis in borderline ovarian tumors (BOTs), and to explore the factors affecting the diagnostic accuracy. Second, to assess the clinical outcomes of misdiagnosed BOT patients. Methods: We perform...

journal_title：Journal of Cancer

authors： Huang Z,Li L,Li C,Ngaujah S,Yao S,Chu R,Xie L,Yang X,Zhang X,Liu P,Jiang J,Zhang Y,Cui B,Song K,Kong B

更新日期：2018-07-16 00:00:00

abstract：OBJECTIVE:To elucidate the oncologic behavior of Micropapillary Urothelial Bladder Carcinoma (MPBC), a rare aggressive variant histology. METHODS:All MPBC patients in SEER 17 database were compared with those with traditional urothelial carcinoma (UC). Kaplan-Meier curves were used to determine OS and CSS. A Cox propo...

journal_title：Journal of Cancer

authors： Vourganti S,Harbin A,Singer EA,Shuch B,Metwalli AR,Agarwal PK

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND AND AIMS:We compared clinicopathologic data and long-term clinical outcomes among patients with non-B and non-C hepatocellular carcinoma (NBNC-HCC) who underwent curative resection (group A, n=129), those with hepatitis B virus-related HCC (group B, n=62) and those with hepatitis C virus-related HCC (group C...

journal_title：Journal of Cancer

authors： Nishikawa H,Arimoto A,Wakasa T,Kita R,Kimura T,Osaki Y

更新日期：2013-07-18 00:00:00

abstract：:Background: Immunotherapy including immune checkpoint blockade, cancer vaccines, and adoptive cell therapy. However, no immune therapies support ovarian cancer. It is not clear whether the neutrophils, the component of the immune system derived from umbilical cord blood play a role in inhibiting the progression of ova...

journal_title：Journal of Cancer

authors： Liu Q,Yang W,Luo N,Liu J,Wu Y,Ding J,Li C,Cheng Z

更新日期：2020-05-18 00:00:00

abstract：:In 2006, a remarkable collaboration between University of Texas MD Anderson Cancer Center clinicians and Texas and New Mexico State legislators led to the formation of a dedicated IBC Research Program and Clinic at MD Anderson. This initiative provided funding and infrastructure to foster coordination of an IBC World ...

journal_title：Journal of Cancer

authors： Woodward WA,Cristofanilli M,Merajver SD,Van Laere S,Pusztai L,Bertucci F,Berditchevski F,Polyak K,Overmoyer B,Devi GR,Sterneck E,Schneider R,Debeb BG,Wang X,van Golen KL,El-Zein R,Rahal OM,Alexander A,Reuben JM,Kris

更新日期：2017-10-09 00:00:00

abstract：:Ovarian cancer, cervical cancer and endometrial cancer are three relatively common malignant cancers of the female reproductive system. Despite improvements in female genital tract cancer detection and development of new therapeutic approaches, there are still poor prognoses and some do not respond to therapeutic patt...

journal_title：Journal of Cancer

authors： Zhu DL,Tuo XM,Rong Y,Zhang K,Guo Y

更新日期：2020-10-21 00:00:00

abstract：:Purpose: Eukaryotic initiation factor 4A-3 (EIF4A3) is an RNA-binding protein (RBP) that is a core component of the exon junction complex (EJC). It has been identified as an important player in post-transcriptional regulation processes. Recently, investigations have focused on EIF4A3 dysfunction in carcinogenesis. The...

journal_title：Journal of Cancer

authors： Lin Y,Zhang J,Cai J,Liang R,Chen G,Qin G,Han X,Yuan C,Liu Z,Li Y,Zou D,Mao Y

更新日期：2018-11-11 00:00:00