Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies.

abstract：:Experiments often challenge the null hypothesis that an intervention, for instance application of non-invasive brain stimulation (NIBS), has no effect on an outcome measure. In conventional statistics, a positive result rejects that hypothesis, but a null result is meaningless. Informally, however, researchers often d...

journal_title：Frontiers in neuroscience

authors： de Graaf TA,Sack AT

更新日期：2018-12-11 00:00:00

abstract：:Extrapancreatic nerves project to pancreatic islets directly or converge onto intrapancreatic ganglia. Intrapancreatic ganglia constitute a complex information-processing center that contains various neurotransmitters and forms an endogenous neural network. Both intrapancreatic ganglia and extrapancreatic nerves have ...

journal_title：Frontiers in neuroscience

authors： Li W,Yu G,Liu Y,Sha L

更新日期：2019-02-20 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive brain disorder with gradual memory loss that correlates to cognitive deficits in the elderly population. Recent studies have shown the potentials of machine learning algorithms to identify biomarkers and functional brain activity patterns across various AD stages using electro...

journal_title：Frontiers in neuroscience

authors： Fan M,Yang AC,Fuh JL,Chou CA

更新日期：2018-10-04 00:00:00

abstract：:The GABAergic neurons in the lateral pontine tegmentum (LPT) play key roles in the regulation of sleep and locomotion. The dysfunction of the LPT is related to neurological disorders such as rapid eye movement sleep behavior disorder and ocular flutter. However, the whole-brain neural connectivity to LPT GABAergic neu...

journal_title：Frontiers in neuroscience

authors： Chen ZK,Yuan XS,Dong H,Wu YF,Chen GH,He M,Qu WM,Huang ZL

更新日期：2019-04-24 00:00:00

abstract：:In functional MRI (fMRI), population receptive field (pRF) models allow a quantitative description of the response as a function of the features of the stimuli that are relevant for each voxel. The most popular pRF model used in fMRI assumes a Gaussian shape in the features space (e.g., the visual field) reducing the ...

journal_title：Frontiers in neuroscience

authors： Lage-Castellanos A,Valente G,Senden M,De Martino F

更新日期：2020-07-30 00:00:00

abstract：:Highlights Simultaneous epileptiform LFPs and single-cell activity can be recorded in the membrane chamber.Interneuron firing can be linked to epileptiform high frequency activity.Fast ripples, unique to chronic epilepsy, can be modeled in ex vivo tissue from TeNT-treated rats. Traditionally, visually-guided patch cla...

journal_title：Frontiers in neuroscience

authors： Morris G,Jiruska P,Jefferys JG,Powell AD

更新日期：2016-11-09 00:00:00

abstract：Introduction:Our hands, with their exquisite sensors, work in concert with our sensing brain to extract sensory attributes of objects as we engage in daily activities. One in two people with stroke experience impaired body sensation, with negative impact on hand use and return to previous valued activities. Valid, quan...

journal_title：Frontiers in neuroscience

authors： Carey LM,Mak-Yuen YYK,Matyas TA

更新日期：2020-09-23 00:00:00

abstract：:High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments. However, test-retest reliability measurements are essential to asc...

journal_title：Frontiers in neuroscience

authors： Boukadi M,Marcotte K,Bedetti C,Houde JC,Desautels A,Deslauriers-Gauthier S,Chapleau M,Boré A,Descoteaux M,Brambati SM

更新日期：2019-01-14 00:00:00

abstract：:Changes in cerebral blood flow (CBF) during a hyperglycemic challenge were mapped, using perfusion-weighted MRI, in a group of non-human primates. Seven female baboons were fasted for 16 h prior to 1-h imaging experiment, performed under general anesthesia, that consisted of a 20-min baseline, followed by a bolus infu...

journal_title：Frontiers in neuroscience

authors： Kochunov P,Wey HY,Fox PT,Lancaster JL,Davis MD,Wang DJ,Lin AL,Bastarrachea RA,Andrade MC,Mattern V,Frost P,Higgins PB,Comuzzie AG,Voruganti VS

更新日期：2017-02-14 00:00:00

abstract：:This work presents the design, implementation, and evaluation of a P300-based brain-machine interface (BMI) developed to control a robotic hand-orthosis. The purpose of this system is to assist patients with amyotrophic lateral sclerosis (ALS) who cannot open and close their hands by themselves. The user of this inter...

journal_title：Frontiers in neuroscience

authors： Delijorge J,Mendoza-Montoya O,Gordillo JL,Caraza R,Martinez HR,Antelis JM

更新日期：2020-11-27 00:00:00

abstract：:Maternal overnutrition modulates body weight, development of metabolic failure and, potentially, neurodegenerative susceptibility in the offspring. Overnutrition sets a chronic pro-inflammatory profile that integrates peripheral and central immune activation nodes, damaging neuronal physiology and survival. Innate imm...

journal_title：Frontiers in neuroscience

authors： Cárdenas-Tueme M,Montalvo-Martínez L,Maldonado-Ruiz R,Camacho-Morales A,Reséndez-Pérez D

更新日期：2020-02-04 00:00:00

abstract：:Compared to standard laboratory protocols, the measurement of psychophysiological signals in real world experiments poses technical and methodological challenges due to external factors that cannot be directly controlled. To address this problem, we propose a hybrid approach based on an immersive and human accessible ...

journal_title：Frontiers in neuroscience

authors： Betella A,Zucca R,Cetnarski R,Greco A,Lanatà A,Mazzei D,Tognetti A,Arsiwalla XD,Omedas P,De Rossi D,Verschure PF

更新日期：2014-09-24 00:00:00

abstract：:Non-linguistic sounds (NLSs) are a core feature of our everyday life and many evoke powerful cognitive and emotional outcomes. The subjective perception of NLSs by humans has occasionally been defined for single percepts, e.g., their pleasantness, whereas many NLSs evoke multiple perceptions. There has also been very ...

journal_title：Frontiers in neuroscience

authors： Burns T,Rajan R

更新日期：2019-07-31 00:00:00

abstract：:Amyloid fibrils are physiologically insoluble biophysically specific β-sheet rich structures formed by the aggregation of misfolded proteins. In vivo tissue amyloid formation is responsible for more than 30 different disease states in humans and other mammals. One of these, Alzheimer's disease (AD), is the most common...

journal_title：Frontiers in neuroscience

authors： Buxbaum JN,Johansson J

更新日期：2017-03-15 00:00:00

abstract：:It is necessary to understand the morphology of the vagus nerve (VN) to design and deliver effective and selective vagus nerve stimulation (VNS) because nerve morphology influences fiber responses to electrical stimulation. Specifically, nerve diameter (and thus, electrode-fiber distance), fascicle diameter, fascicula...

journal_title：Frontiers in neuroscience

authors： Pelot NA,Goldhagen GB,Cariello JE,Musselman ED,Clissold KA,Ezzell JA,Grill WM

更新日期：2020-11-04 00:00:00

abstract：:How speech signals are analyzed and represented remains a foundational challenge both for cognitive science and neuroscience. A growing body of research, employing various behavioral and neurobiological experimental techniques, now points to the perceptual relevance of both phoneme-sized (10-40 Hz modulation frequency...

journal_title：Frontiers in neuroscience

authors： Chait M,Greenberg S,Arai T,Simon JZ,Poeppel D

更新日期：2015-06-16 00:00:00

abstract：:Nocturnal secretion of melatonin from the pineal gland may affect central and peripheral timing, in addition to its well-known involvement in the control of seasonal physiology. The Syrian hamster is a photoperiodic species, which displays gonadal atrophy and increased adiposity when adapted to short (winter-like) pho...

journal_title：Frontiers in neuroscience

authors： Chakir I,Dumont S,Pévet P,Ouarour A,Challet E,Vuillez P

更新日期：2015-05-27 00:00:00

abstract：:We present a spiking neural network model of the thalamic Lateral Geniculate Nucleus (LGN) developed on SpiNNaker, which is a state-of-the-art digital neuromorphic hardware built with very-low-power ARM processors. The parallel, event-based data processing in SpiNNaker makes it viable for building massively parallel n...

journal_title：Frontiers in neuroscience

authors： Sen-Bhattacharya B,Serrano-Gotarredona T,Balassa L,Bhattacharya A,Stokes AB,Rowley A,Sugiarto I,Furber S

更新日期：2017-08-09 00:00:00

abstract：:Acupuncture is a traditional Chinese medicine treatment that has widely been used to modulate gastrointestinal dysfunction caused by irritable bowel syndrome (IBS) and to alleviate the resulting pain. Recent studies have shown that gastrointestinal dysfunction caused by IBS is associated with dysregulation of the brai...

journal_title：Frontiers in neuroscience

authors： Ma K,Liu Y,Shao W,Sun J,Li J,Fang X,Li J,Wang Z,Zhang D

更新日期：2020-12-15 00:00:00

abstract：:The combination of electromyography (EMG) and transcranial magnetic stimulation (TMS) offers a powerful non-invasive approach for investigating corticospinal excitability in both humans and animals. Acquiring and analyzing the data produced with this combination of tools requires overcoming multiple technical hurdles....

journal_title：Frontiers in neuroscience

authors： Jackson N,Greenhouse I

更新日期：2019-09-13 00:00:00

abstract：:The melanin-concentrating hormone (MCH) system is a robust integrator of exogenous and endogenous information, modulating arousal and energy balance in mammals. Its predominant function in teleosts, however, is to concentrate melanin in the scales, contributing to the adaptive color change observed in several teleost ...

journal_title：Frontiers in neuroscience

authors： Diniz GB,Bittencourt JC

更新日期：2019-11-26 00:00:00

abstract：:The ability to delegate control over repetitive tasks from higher to lower neural centers may be a fundamental innovation in human cognition. Plausibly, the massive neurocomputational challenges associated with the mastery of balance during the evolution of bipedality in proto-humans provided a strong selective advant...

journal_title：Frontiers in neuroscience

authors： Shine JM,Shine R

更新日期：2014-04-29 00:00:00

abstract：:Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great potential for combating bacterial resistance. AMPs can be both bacteriostatic and bactericidal, induce rapid killing and display a lower propensity to develop resistance than do conventional antibiotics. Despite significant progres...

journal_title：Frontiers in neuroscience

authors： Li J,Koh JJ,Liu S,Lakshminarayanan R,Verma CS,Beuerman RW

更新日期：2017-02-14 00:00:00

abstract：:Intracortical electrodes for brain-machine interfaces rely on intimate contact with tissues for recording signals and stimulating neurons. However, the long-term viability of intracortical electrodes in vivo is poor, with a major contributing factor being the development of a glial scar. In vivo approaches for evaluat...

journal_title：Frontiers in neuroscience

authors： Gilmour A,Poole-Warren L,Green RA

更新日期：2019-12-17 00:00:00

abstract：:Mu/beta rhythms are well-studied brain activities that originate from sensorimotor cortices. These rhythms reveal spectral changes in alpha and beta bands induced by movements of different body parts, e.g., hands and limbs, in electroencephalography (EEG) signals. However, less can be revealed in them about movements ...

journal_title：Frontiers in neuroscience

authors： Xiao R,Ding L

更新日期：2015-09-01 00:00:00

abstract：:A vast literature implicates the ventral striatum in the processing of reward-related information and in mediating the impact of such information on behavior. It is characterized by heterogeneity at the local circuit, connectivity, and functional levels. A tool for dissecting this complex structure that has received r...

journal_title：Frontiers in neuroscience

authors： van der Meer MA,Kalenscher T,Lansink CS,Pennartz CM,Berke JD,Redish AD

更新日期：2010-09-15 00:00:00

abstract：:Peripheral nerves are composed of complex layered anatomical structures, including epineurium, perineurium, and endoneurium. Perineurium and endoneurium contain many physical barriers, including the blood-nerve barrier at endoneurial vessels and the perineurial barrier. These physical barriers help to eliminate flux p...

journal_title：Frontiers in neuroscience

authors： Liu Q,Wang X,Yi S

更新日期：2018-08-23 00:00:00

abstract：Background:Individuals are able to perform goal-directed behaviors thanks to executive functions. According to the neurovisceral integration model, executive functions are upregulated by brain areas such as the prefrontal and cingulate cortices, which are also crucially involved in controlling cardiac vagal activity. A...

journal_title：Frontiers in neuroscience

authors： Borges U,Knops L,Laborde S,Klatt S,Raab M

更新日期：2020-05-25 00:00:00

abstract：:Gene Expression Programming (GEP), a variant of Genetic Programming (GP), is a well established technique for automatic generation of computer programs. Due to the flexible representation, GEP has long been concerned as a classification algorithm for various applications. Whereas, GEP cannot be extended to multi-class...

journal_title：Frontiers in neuroscience

authors： Wei T,Zhong J

更新日期：2020-01-17 00:00:00

abstract：:While the transient receptor potential vanilloid 1 (TRPV1) ion channel, a non-selective calcium-permeable cation channel with high Ca2+ permeability, mainly integrates physical and chemical stimuli for nociception, recent studies suggest that it has a role beyond a noxious thermal sensor. In fact, TRPV1 is presently b...

journal_title：Frontiers in neuroscience

authors： Zhang M,Ruwe D,Saffari R,Kravchenko M,Zhang W

更新日期：2020-02-07 00:00:00