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Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits.

Abstract：

:Altered immune functioning has been demonstrated in individuals with autism spectrum disorder (ASD). The current study explores the relationship between perceived immune functioning and experiencing ASD traits in healthy young adults. N = 410 students from Utrecht University completed a survey on immune functioning and autistic traits. In addition to a 1-item perceived immune functioning rating, the Immune Function Questionnaire (IFQ) was completed to assess perceived immune functioning. The Dutch translation of the Autism-Spectrum Quotient (AQ) was completed to examine variation in autistic traits, including the domains "social insights and behavior", "difficulties with change", "communication", "phantasy and imagination", and "detail orientation". The 1-item perceived immune functioning score did not significantly correlate with the total AQ score. However, a significant negative correlation was found between perceived immune functioning and the AQ subscale "difficulties with change" (r = -0.119, p = 0.019). In women, 1-item perceived immune functioning correlated significantly with the AQ subscales "difficulties with change" (r = -0.149, p = 0.029) and "communication" (r = -0.145, p = 0.032). In men, none of the AQ subscales significantly correlated with 1-item perceived immune functioning. In conclusion, a modest relationship between perceived immune functioning and several autistic traits was found.

journal_name

Int J Environ Res Public Health

journal_title

International journal of environmental research and public health

authors

Mackus M,Kruijff D,Otten LS,Kraneveld AD,Garssen J,Verster JC

doi

10.3390/ijerph14040409

subject

Has Abstract

pub_date

2017-04-12 00:00:00

issue

4

eissn

1661-7827

issn

1660-4601

pii

ijerph14040409

journal_volume

14

pub_type

杂志文章

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