Abstract:
:Natural killer (NK) cells are lymphocytes of the innate immune system able to kill different targets such as cancer cells and virally infected cells without prior activation making then attractive candidates for cancer immunotherapy. Umbilical cord blood (UCB) has become a source of hematopoietic stem cells for transplantation but as we gain a better understanding of the characteristics of each immune cell that UCB contains, we will also be able to develop new cell therapies for cancer. In this review, we present what is currently known of the phenotype and functions of UCB NK cells and how these cells could be used in the future for cancer immunotherapy.
journal_name
Front Immunoljournal_title
Frontiers in immunologyauthors
Sarvaria A,Jawdat D,Madrigal JA,Saudemont Adoi
10.3389/fimmu.2017.00329subject
Has Abstractpub_date
2017-03-23 00:00:00pages
329issn
1664-3224journal_volume
8pub_type
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