Abstract：
:Human exposure to mercury is still a major public health concern. In this context, children have a higher susceptibility to adverse neurological mercury effects, compared to adults with similar exposures. Moreover, there exists a marked variability of personal response to detrimental mercury action, in particular among population groups with significant mercury exposure. New scientific evidence on genetic backgrounds has raised the issue of whether candidate susceptibility genes can make certain individuals more or less vulnerable to mercury toxicity. In this review, the aim is to evaluate a new genetic dimension and its involvement in mercury risk assessment, focusing on the important role played by relevant polymorphisms, located in attractive gene targets for mercury toxicity. Existing original articles on epidemiologic research which report a direct link between the genetic basis of personal vulnerability and different mercury repercussions on human health will be reviewed. Based on this evidence, a careful evaluation of the significant markers of susceptibility will be suggested, in order to obtain a powerful positive "feedback" to improve the quality of life. Large consortia of studies with clear phenotypic assessments will help clarify the "window of susceptibility" in the human health risks due to mercury exposure.
journal_name
Int J Environ Res Public Healthauthors
Andreoli V,Sprovieri Fdoi
10.3390/ijerph14010093subject
Has Abstractpub_date
2017-01-18 00:00:00issue
1eissn
1661-7827issn
1660-4601pii
ijerph14010093journal_volume
14pub_type
杂志文章,评审abstract：:Hypertension has been the leading risk factor contributing to cardiovascular morbidity and mortality, which needs comprehensive measures to manage and can be controlled effectively in primary care. In the health care context of South Korea, where specialists can see patients directly at their own community clinics and...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph15020272
更新日期：2018-02-05 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17155462
更新日期：2020-07-29 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章,随机对照试验
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更新日期：2019-07-16 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2019-06-21 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2016-05-05 00:00:00
abstract：:Due to an error during production, Section 3 [...]. ...
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pub_type： 已发布勘误
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更新日期：2020-12-11 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
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更新日期：2014-03-07 00:00:00
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pub_type： 杂志文章
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更新日期：2020-02-08 00:00:00
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更新日期：2015-11-12 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
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更新日期：2018-01-30 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16183486
更新日期：2019-09-19 00:00:00
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pub_type： 杂志文章
doi：10.3390/ijerph7030927
更新日期：2010-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-04-16 00:00:00
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pub_type： 杂志文章
doi：10.3390/ijerph15112474
更新日期：2018-11-06 00:00:00
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pub_type： 杂志文章
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更新日期：2021-01-04 00:00:00
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pub_type： 杂志文章
doi：10.3390/ijerph17093174
更新日期：2020-05-02 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph15040787
更新日期：2018-04-18 00:00:00
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doi：10.3390/ijerph17207483
更新日期：2020-10-14 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
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更新日期：2020-07-06 00:00:00
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更新日期：2020-12-08 00:00:00
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pub_type： 杂志文章
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更新日期：2020-08-17 00:00:00
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doi：10.3390/ijerph13050503
更新日期：2016-05-14 00:00:00
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更新日期：2020-12-04 00:00:00
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journal_title：International journal of environmental research and public health
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更新日期：2020-06-19 00:00:00
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journal_title：International journal of environmental research and public health
pub_type： 杂志文章
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更新日期：2020-08-28 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章,meta分析,评审
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更新日期：2013-10-31 00:00:00
abstract：:The prevention of suicide and suicide-related behaviour are key policy priorities in Australia and internationally. The World Health Organization has recommended that member states develop self-harm surveillance systems as part of their suicide prevention efforts. This is also a priority under Australia's Fifth Nation...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17249385
更新日期：2020-12-15 00:00:00
