An In vivo Multi-Modal Structural Template for Neonatal Piglets Using High Angular Resolution and Population-Based Whole-Brain Tractography.

Abstract:

:An increasing number of applications use the postnatal piglet model in neuroimaging studies, however, these are based primarily on T1 weighted image templates. There is a growing need for a multimodal structural brain template for a comprehensive depiction of the piglet brain, particularly given the growing applications of diffusion weighted imaging for characterizing tissue microstructures and white matter organization. In this study, we present the first multimodal piglet structural brain template which includes a T1 weighted image with tissue segmentation probability maps, diffusion weighted metric templates with multiple diffusivity maps, and population-based whole-brain fiber tracts for postnatal piglets. These maps provide information about the integrity of white matter that is not available in T1 images alone. The availability of this diffusion weighted metric template will contribute to the structural imaging analysis of the postnatal piglet brain, especially models that are designed for the study of white matter diseases. Furthermore, the population-based whole-brain fiber tracts permit researchers to visualize the white matter connections in the piglet brain across subjects, guiding the delineation of a specific white matter region for structural analysis where current diffusion data is lacking. Researchers are able to augment the tracts by merging tracts from their own data to the population-based fiber tracts and thus improve the confidence of the population-wise fiber distribution.

journal_name

Front Neuroanat

authors

Zhong J,Chen DQ,Walker M,Waspe A,Looi T,Piorkowska K,Drake JM,Hodaie M

doi

10.3389/fnana.2016.00092

subject

Has Abstract

pub_date

2016-09-27 00:00:00

pages

92

issn

1662-5129

journal_volume

10

pub_type

杂志文章
  • Comparative Analysis of Nkx2.1 and Islet-1 Expression in Urodele Amphibians and Lungfishes Highlights the Pattern of Forebrain Organization in Early Tetrapods.

    abstract::Expression patterns of Nkx2.1 and Islet-1 (Isl1), which encode transcription factors that are key in the regionalization of the forebrain, were analyzed by combined immunohistochemical methods in young adult specimens of two lungfishes (Neoceratodus forsteri and Protopterus dolloi) and a urodele amphibian (Pleurodeles...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00042

    authors: Moreno N,López JM,Morona R,Lozano D,Jiménez S,González A

    更新日期:2018-05-18 00:00:00

  • Neocortical development as an evolutionary platform for intragenomic conflict.

    abstract::Embryonic development in mammals has evolved a platform for genomic conflict between mothers and embryos and, by extension, between maternal and paternal genomes. The evolutionary interests of the mother and embryo may be maximized through the promotion of sex-chromosome genes and imprinted alleles, resulting in the r...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00002

    authors: Lewitus E,Kalinka AT

    更新日期:2013-04-09 00:00:00

  • The Dual Nature of Onuf's Nucleus: Neuroanatomical Features and Peculiarities, in Health and Disease.

    abstract::Onuf's nucleus is a small group of neurons located in the ventral horns of the sacral spinal cord. The motor neurons (MNs) of Onuf's nucleus innervate striated voluntary muscles of the pelvic floor and are histologically and biochemically comparable to the other somatic spinal MNs. However, curiously, these neurons al...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2020.572013

    authors: Schellino R,Boido M,Vercelli A

    更新日期:2020-09-04 00:00:00

  • Some predictions of Rafael Lorente de Nó 80 years later.

    abstract::Rafael Lorente de Nó, the youngest of Santiago Ramón y Cajal disciples, was one of the last Century's more influential researches in neuroscience. This assay highlights two fundamental contributions of Rafael Lorente de Nó to neurobiology: the intrinsic organization of the mammalian cerebral cortex and the basic physi...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2014.00147

    authors: Larriva-Sahd JA

    更新日期:2014-12-03 00:00:00

  • Topographic Organization of Inferior Olive Projections to the Zebrin II Stripes in the Pigeon Cerebellar Uvula.

    abstract::This study was aimed at mapping the organization of the projections from the inferior olive (IO) to the ventral uvula in pigeons. The uvula is part of the vestibulocerebellum (VbC), which is involved in the processing of optic flow resulting from self-motion. As in other areas of the cerebellum, the uvula is organized...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00018

    authors: Craciun I,Gutiérrez-Ibáñez C,Corfield JR,Hurd PL,Wylie DR

    更新日期:2018-03-15 00:00:00

  • Neuronal Organization of Deep Brain Opsin Photoreceptors in Adult Teleosts.

    abstract::Biological impacts of light beyond vision, i.e., non-visual functions of light, signify the need to better understand light detection (or photoreception) systems in vertebrates. Photopigments, which comprise light-absorbing chromophores bound to a variety of G-protein coupled receptor opsins, are responsible for visua...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2016.00048

    authors: Hang CY,Kitahashi T,Parhar IS

    更新日期:2016-04-27 00:00:00

  • Histogenetic Radial Models as Aids to Understanding Complex Brain Structures: The Amygdalar Radial Model as a Recent Example.

    abstract::The radial dimension expands during central nervous system development after the proliferative neuroepithelium is molecularly patterned. The process is associated with neurogenesis, radial glia scaffolding, and migration of immature neurons into the developing mantle stratum. Radial histogenetic units, defined as a de...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.590011

    authors: Garcia-Calero E,Puelles L

    更新日期:2020-11-10 00:00:00

  • Morphological changes of glutamatergic synapses in animal models of Parkinson's disease.

    abstract::The striatum and the subthalamic nucleus (STN) are the main entry doors for extrinsic inputs to reach the basal ganglia (BG) circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is anatomical, functional and neurochemical evidence that glutamatergic ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2015.00117

    authors: Villalba RM,Mathai A,Smith Y

    更新日期:2015-09-25 00:00:00

  • Fast 3-D Imaging of Brain Organoids With a New Single-Objective Planar-Illumination Two-Photon Microscope.

    abstract::Human inducible pluripotent stem cells (hiPSCs) hold a large potential for disease modeling. hiPSC-derived human astrocyte and neuronal cultures permit investigations of neural signaling pathways with subcellular resolution. Combinatorial cultures, and three-dimensional (3-D) embryonic bodies (EBs) enlarge the scope o...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00077

    authors: Rakotoson I,Delhomme B,Djian P,Deeg A,Brunstein M,Seebacher C,Uhl R,Ricard C,Oheim M

    更新日期:2019-08-20 00:00:00

  • A stereological study of synapse number in the epileptic human hippocampus.

    abstract::Hippocampal sclerosis is the most frequent pathology encountered in resected mesial temporal structures from patients with intractable temporal lobe epilepsy (TLE). Here, we have used stereological methods to compare the overall density of synapses and neurons between non-sclerotic and sclerotic hippocampal tissue obt...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00008

    authors: Alonso-Nanclares L,Kastanauskaite A,Rodriguez JR,Gonzalez-Soriano J,Defelipe J

    更新日期:2011-02-24 00:00:00

  • Expansion Light Sheet Microscopy Resolves Subcellular Structures in Large Portions of the Songbird Brain.

    abstract::Expansion microscopy and light sheet imaging (ExLSM) provide a viable alternative to existing tissue clearing and large volume imaging approaches. The analysis of intact volumes of brain tissue presents a distinct challenge in neuroscience. Recent advances in tissue clearing and light sheet microscopy have re-addresse...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00002

    authors: Düring DN,Rocha MD,Dittrich F,Gahr M,Hahnloser RHR

    更新日期:2019-01-31 00:00:00

  • Origin and Migration of Olfactory Cajal-Retzius Cells.

    abstract::Early telencephalic development involves the migration of diverse cell types that can be identified by specific molecular markers. Most prominent among them are Cajal-Retzius (CR) cells that emanate mainly from the cortical hem and to a lesser extent from rostrolateral, septal and caudo-medial regions. One additional ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2017.00097

    authors: Frade-Pérez MD,Miquelajáuregui A,Varela-Echavarría A

    更新日期:2017-11-01 00:00:00

  • Comparative gene expression analysis among vocal learners (bengalese finch and budgerigar) and non-learners (quail and ring dove) reveals variable cadherin expressions in the vocal system.

    abstract::Birds use various vocalizations to communicate with one another, and some are acquired through learning. So far, three families of birds (songbirds, parrots, and hummingbirds) have been identified as having vocal learning ability. Previously, we found that cadherins, a large family of cell-adhesion molecules, show voc...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00028

    authors: Matsunaga E,Okanoya K

    更新日期:2011-04-20 00:00:00

  • Laminar Pattern of Projections Indicates the Hierarchical Organization of the Anterior Cingulate-Temporal Lobe Emotion System.

    abstract::The anterior cingulate cortex (ACC), surrounding the genu of the corpus callosum, plays important roles in emotional processing and is functionally divided into the dorsal, perigenual, and subgenual subregions (dACC, pgACC, and sgACC, respectively). Previous studies have suggested that the pgACC and sgACC have distinc...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00074

    authors: Sakata H,Kim Y,Nejime M,Konoike N,Miyachi S,Nakamura K

    更新日期:2019-07-31 00:00:00

  • Revisiting enigmatic cortical calretinin-expressing interneurons.

    abstract::Cortical calretinin (CR)-expressing interneurons represent a heterogeneous subpopulation of about 10-30% of GABAergic interneurons, which altogether total ca. 12-20% of all cortical neurons. In the rodent neocortex, CR cells display different somatodendritic morphologies ranging from bipolar to multipolar but the bipo...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2014.00052

    authors: Cauli B,Zhou X,Tricoire L,Toussay X,Staiger JF

    更新日期:2014-06-24 00:00:00

  • The Golgi Apparatus of Neocortical Glial Cells During Hibernation in the Syrian Hamster.

    abstract::Hibernating mammals undergo torpor periods characterized by a general decrease in body temperature, metabolic rate, and brain activity accompanied by complex adaptive brain changes that appear to protect the brain from extreme conditions of hypoxia and low temperatures. These processes are accompanied by morphological...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00092

    authors: León-Espinosa G,DeFelipe J,Muñoz A

    更新日期:2019-11-19 00:00:00

  • Striatal spine plasticity in Parkinson's disease.

    abstract::Striatal dopamine (DA) denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson's disease. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkeys, spines contacted either by cortical or thalamic glutamatergic terminals are severely affected on ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2010.00133

    authors: Villalba RM,Smith Y

    更新日期:2010-12-10 00:00:00

  • Huntington's Disease and Striatal Signaling.

    abstract::Huntington's Disease (HD) is the most frequent neurodegenerative disease caused by an expansion of polyglutamines (CAG). The main clinical manifestations of HD are chorea, cognitive impairment, and psychiatric disorders. The transmission of HD is autosomal dominant with a complete penetrance. HD has a single genetic c...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00055

    authors: Roze E,Cahill E,Martin E,Bonnet C,Vanhoutte P,Betuing S,Caboche J

    更新日期:2011-08-23 00:00:00

  • Structural Connectivity of the Anterior Cingulate Cortex, Claustrum, and the Anterior Insula of the Mouse.

    abstract::The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00100

    authors: Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

    更新日期:2018-11-26 00:00:00

  • Subcollicular projections to the auditory thalamus and collateral projections to the inferior colliculus.

    abstract::Experiments in several species have identified direct projections to the medial geniculate nucleus (MG) from cells in subcollicular auditory nuclei. Moreover, many cochlear nucleus cells that project to the MG send collateral projections to the inferior colliculus (IC) (Schofield et al., 2014). We conducted three expe...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2014.00070

    authors: Schofield BR,Mellott JG,Motts SD

    更新日期:2014-07-18 00:00:00

  • How the cortex gets its folds: an inside-out, connectivity-driven model for the scaling of Mammalian cortical folding.

    abstract::Larger mammalian cerebral cortices tend to have increasingly folded surfaces, often considered to result from the lateral expansion of the gray matter (GM), which, in a volume constrained by the cranium, causes mechanical compression that is relieved by inward folding of the white matter (WM), or to result from differ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2012.00003

    authors: Mota B,Herculano-Houzel S

    更新日期:2012-02-02 00:00:00

  • Structural Covariance Changes of Anterior and Posterior Hippocampus During Musical Training in Young Adults.

    abstract::Musical training can induce the functional and structural changes of the hippocampus. The hippocampus is not a homogeneous structure which can be divided into anterior and posterior parts along its longitudinal axis, and the whole-brain structural covariances of anterior (aHC) and posterior hippocampus (pHC) show dist...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.00020

    authors: Guo P,Li Q,Wang X,Li X,Wang S,Xie Y,Xie Y,Fu Z,Zhang X,Li S

    更新日期:2020-05-19 00:00:00

  • An Alternative to Dye-Based Approaches to Remove Background Autofluorescence From Primate Brain Tissue.

    abstract::Brain tissue contains autofluorescing elements that potentially impede accurate identification of neurons when visualized with fluorescent microscopy. Age-related accumulation of molecules with autofluorescent properties, such as lipofuscin, can possess spectral profiles that invade the typical emission range of fluor...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00073

    authors: Pyon WS,Gray DT,Barnes CA

    更新日期:2019-07-18 00:00:00

  • Automatic Mitochondria Segmentation for EM Data Using a 3D Supervised Convolutional Network.

    abstract::Recent studies have supported the relation between mitochondrial functions and degenerative disorders related to ageing, such as Alzheimer's and Parkinson's diseases. Since these studies have exposed the need for detailed and high-resolution analysis of physical alterations in mitochondria, it is necessary to be able ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00092

    authors: Xiao C,Chen X,Li W,Li L,Wang L,Xie Q,Han H

    更新日期:2018-11-02 00:00:00

  • Axonal Segregation and Role of the Vesicular Glutamate Transporter VGLUT3 in Serotonin Neurons.

    abstract::A subset of monoamine neurons releases glutamate as a cotransmitter due to presence of the vesicular glutamate transporters VGLUT2 or VGLUT3. In addition to mediating vesicular loading of glutamate, it has been proposed that VGLUT3 enhances serotonin (5-HT) vesicular loading by the vesicular monoamine transporter (VMA...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2016.00039

    authors: Voisin AN,Mnie-Filali O,Giguère N,Fortin GM,Vigneault E,El Mestikawy S,Descarries L,Trudeau LÉ

    更新日期:2016-04-12 00:00:00

  • Contribution of pheromones processed by the main olfactory system to mate recognition in female mammals.

    abstract::Until recently it was widely believed that the ability of female mammals (with the likely exception of women) to identify and seek out a male breeding partner relied on the detection of non-volatile male pheromones by the female's vomeronasal organ (VNO) and their subsequent processing by a neural circuit that include...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2012.00020

    authors: Baum MJ

    更新日期:2012-06-05 00:00:00

  • Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequences.

    abstract::Over the last 60 years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioral pathologies, the cerebellum is a natural home for studies of cell specifi...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2013.00029

    authors: Basson MA,Wingate RJ

    更新日期:2013-09-03 00:00:00

  • Brain damages in ketamine addicts as revealed by magnetic resonance imaging.

    abstract::Ketamine, a known antagonist of N-methyl-D-aspartic (NMDA) glutamate receptors, had been used as an anesthetic particularly for pediatric or for cardiac patients. Unfortunately, ketamine has become an abusive drug in many parts of the world while chronic and prolonged usage led to damages of many organs including the ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00023

    authors: Wang C,Zheng D,Xu J,Lam W,Yew DT

    更新日期:2013-07-17 00:00:00

  • Ontogenesis of NADPH-diaphorase positive neurons in guinea pig neocortex.

    abstract::In mammalian cerebrum there exist two distinct types of interneurons expressing nitric oxide synthase (NOS). Type I neurons are large in size and exhibit heavy nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) histochemical reaction, while type II cells are small with light NADPH-d reactivity. The time ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00011

    authors: Liu C,Yang Y,Hu X,Li JM,Zhang XM,Cai Y,Li Z,Yan XX

    更新日期:2015-02-16 00:00:00

  • The Representation of White Matter in the Central Nervous System.

    abstract::The white matter of the central nervous system (CNS) is difficult to represent in anatomy because it is located predominantly "between" other anatomical entities. In a classic presentation, like a cross section of a brain segment, white matter is present and can be labeled adequately. Several appearances of the same e...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00102

    authors: Baud R,Sprumont P,Ten Donkelaar HJ

    更新日期:2018-12-13 00:00:00