Patterns of Co-Occurring Gray Matter Concentration Loss across the Huntington Disease Prodrome.

abstract：:In order to better understand how to identify and treat student-athletes who experience concussions, better insight into reporting behavior of athletes is needed. This study aims to identify information influencing athletes' attitudes toward reporting their concussions and the perceived trajectory of their recovery bo...

journal_title：Frontiers in neurology

authors： Oddo A,O'Conor E,Shore S,Piraino M,Gibney K,Tsao J,Stanfill AG

更新日期：2019-07-05 00:00:00

abstract：:With the demographic shift of the global population toward longer life expectancy, the number of people living with Alzheimer's disease (AD) has rapidly expanded and is projected to triple by the year 2050. Current treatments provide symptomatic relief but do not affect the underlying pathology of the disease. Therapi...

journal_title：Frontiers in neurology

authors： Ritter A,Cummings J

更新日期：2015-08-31 00:00:00

abstract：:Epilepsy may reflect a focal abnormality of cerebral tissue, but the generation of seizures typically involves propagation of abnormal activity through cerebral networks. We examined epileptiform discharges (spikes) with dense array electroencephalography (dEEG) in five patients to search for the possible engagement o...

journal_title：Frontiers in neurology

authors： Song J,Tucker DM,Gilbert T,Hou J,Mattson C,Luu P,Holmes MD

更新日期：2013-05-15 00:00:00

abstract：:Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initia...

journal_title：Frontiers in neurology

authors： Han J,Mao W,Ni J,Wu Y,Liu J,Bai L,Shi M,Tu J,Ning X,Wang J

更新日期：2020-01-23 00:00:00

abstract：:GLUT1 Deficiency Syndrome (GLUT1-DS) is a rare and potentially treatable neurometabolic condition, caused by a reduced glucose transport into the brain and clinically characterized by an epileptic encephalopathy with movement disorders. A wide inter-intrafamilial phenotypic variability has been reported. Very-long-cha...

journal_title：Frontiers in neurology

authors： Musumeci O,Ferlazzo E,Rodolico C,Gambardella A,Gagliardi M,Aguglia U,Toscano A

更新日期：2020-06-23 00:00:00

abstract：:Glaucoma damages retinal ganglion cells, including intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells modulate various non-visual physiological and psychological functions which are modulated by light. In patients with glaucoma, we assessed the effect of daily bright light exposure (LE) on sever...

journal_title：Frontiers in neurology

authors： Kawasaki A,Udry M,El Wardani M,Münch M

更新日期：2021-01-15 00:00:00

abstract：:Seizures are an infrequent and serious neurological complication of SARS-CoV-2 infection, with limited data describing the etiology and the clinical context in which these occur or the associated electrographic and imaging findings. This series details four cases of seizures occurring in patients with COVID-19 with di...

journal_title：Frontiers in neurology

authors： Hwang ST,Ballout AA,Mirza U,Sonti AN,Husain A,Kirsch C,Kuzniecky R,Najjar S

更新日期：2020-11-05 00:00:00

abstract：:Introduction: Symptoms following a mild traumatic brain injury (mTBI) usually resolve quickly but may persist past 3 months in up to 15% of children. Mechanisms of mTBI recovery are poorly understood, but may involve alterations in cortical neurophysiology. Transcranial Magnetic Stimulation (TMS) can non-invasively in...

journal_title：Frontiers in neurology

authors： King R,Kirton A,Zewdie E,Seeger TA,Ciechanski P,Barlow KM

更新日期：2019-05-17 00:00:00

abstract：:We describe three patients diagnosed with bilateral vestibular dysfunction associated with the jet propellant type-eight (JP-8) fuel exposure. Chronic exposure to aromatic and aliphatic hydrocarbons, which are the main constituents of JP-8 military aircraft jet fuel, occurred over 3-5 years' duration while working on ...

journal_title：Frontiers in neurology

authors： Fife TD,Robb MJA,Steenerson KK,Saha KC

更新日期：2018-05-16 00:00:00

abstract：:Objective: To investigate an MRI-based etiological classification for acute isolated pontine infarcts and to assess differences in vascular risk factors, clinical characteristics and WMH burden among the etiological subtypes. Methods: All participants from SMART cohort with DWI-proven acute isolated pontine infarcts (...

journal_title：Frontiers in neurology

authors： Zhou L,Yao M,Peng B,Zhu Y,Ni J,Cui L

更新日期：2018-10-09 00:00:00

abstract：:Background: Essential tremor (ET) is a common, progressive neurological syndrome with bilateral upper-limb dysfunction of at least 3-year duration, with or without tremor in other body locations. This disorder has a negative impact on daily function and quality of life. A single oral therapy has been approved by FDA f...

journal_title：Frontiers in neurology

authors： Papapetropoulos S,Lee MS,Boyer S,Newbold EJ

更新日期：2019-06-11 00:00:00

abstract：:Patients with epilepsy and treated with antiepileptic drugs (AEDs) may develop metabolic bone disease; however, the exact pathogenesis of bone loss with AEDs is still unclear. Included were 75 adults with epilepsy (mean age: 31.90 ± 5.62 years; duration of treatment with AEDs: 10.57 ± 3.55 years) and 40 matched health...

journal_title：Frontiers in neurology

authors： Hamed SA,Moussa EM,Youssef AH,Abd ElHameed MA,NasrEldin E

更新日期：2014-08-04 00:00:00

abstract：:Background: Studies have investigated the lipid profile in amyotrophic lateral sclerosis (ALS), including the levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and higher low-density lipoprotein (LDL), and the associations with mortality of ALS, but the results were inconsistent. The...

journal_title：Frontiers in neurology

authors： Liu J,Luo X,Chen X,Shang H

更新日期：2020-10-15 00:00:00

abstract：:Objective: Simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) were applied to investigate the abnormalities in the topological characteristics of functional brain networks during non-rapid eye movement(NREM)sleep. And we investigated its relationship with cognitive abnormalities...

journal_title：Frontiers in neurology

authors： Zhu X,Ni K,Tan H,Liu Y,Zeng Y,Yu B,Guo Q,Xiao L

更新日期：2021-01-11 00:00:00

abstract：:Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language su...

journal_title：Frontiers in neurology

authors： Liu X,He F,Chen Z,Liu P,Peng G

更新日期：2018-02-16 00:00:00

abstract：:Disorders of the central nervous system sometimes cause severe sensory motor paralysis accompanied by gait impairment. Recently, there are several reports on the effectiveness of robot-assisted gait training for patients experiencing these issues. The purpose of this case report was to assess the neuromechanical effec...

journal_title：Frontiers in neurology

authors： Kadone H,Kubota S,Abe T,Noguchi H,Miura K,Koda M,Shimizu Y,Hada Y,Sankai Y,Suzuki K,Yamazaki M

更新日期：2020-03-31 00:00:00

abstract：:Functional connectivity maps using resting-state functional magnetic resonance imaging (rs-fMRI) can closely resemble task fMRI activation patterns, suggesting that resting-state brain activity may predict task-evoked activation or behavioral performance. However, this conclusion was mostly drawn upon a healthy popula...

journal_title：Frontiers in neurology

authors： Hu J,Du J,Xu Q,Yang F,Zeng F,Dai XJ,Liu X,Lu G,Zhang Z

更新日期：2017-07-19 00:00:00

abstract：:The endothelium is a thin monolayer of specialized cells that lines the luminal wall of blood vessels and constitutes the critical innermost portion of the physical barrier between the blood and the brain termed the blood-brain barrier (BBB). Aberrant changes in the endothelium occur in many neuropathological states, ...

journal_title：Frontiers in neurology

authors： Lutton EM,Farney SK,Andrews AM,Shuvaev VV,Chuang GY,Muzykantov VR,Ramirez SH

更新日期：2019-06-06 00:00:00

abstract：:Introduction: Persons with MS (PwMS) have markedly reduced push-off and toe-clearance during gait compared to healthy subjects (HS). These deficits may result from alterations in neuromotor control at the ankle. To optimize rehabilitation interventions for PwMS, a crucial step is to evaluate if and how altered neuromo...

journal_title：Frontiers in neurology

authors： Jonsdottir J,Lencioni T,Gervasoni E,Crippa A,Anastasi D,Carpinella I,Rovaris M,Cattaneo D,Ferrarin M

更新日期：2020-07-24 00:00:00

abstract：:The pattern of epileptic seizures is often considered unpredictable and the interval between events without correlation. A number of studies have examined the possibility that seizure activity respects a power-law relationship, both in terms of event magnitude and inter-event intervals. Such relationships are found in...

journal_title：Frontiers in neurology

authors： Cook MJ,Varsavsky A,Himes D,Leyde K,Berkovic SF,O'Brien T,Mareels I

更新日期：2014-10-24 00:00:00

abstract：OBJECT:Aneurysmal subarachnoid hemorrhage (aSAH) is a common cause of death or long-term disability. Despite advances in neurocritical care, there is still only a very limited ability to monitor the development of secondary brain injury or to predict neurological outcome after aSAH. Soluble urokinase-type plasminogen a...

journal_title：Frontiers in neurology

authors： Kiiski H,Jalkanen V,Ala-Peijari M,Hämäläinen M,Moilanen E,Peltola J,Tenhunen J

更新日期：2017-04-18 00:00:00

abstract：:Poststroke depression (PSD) is the most prevalent psychiatric disorder after stroke, which is independently correlated with negative clinical outcome. The identification of specific biomarkers could help to increase the sensitivity of PSD diagnosis and elucidate its pathophysiological mechanisms. The aim of current st...

journal_title：Frontiers in neurology

authors： Levada OA,Troyan AS

更新日期：2018-07-16 00:00:00

abstract：:Semicircular canal afferents sense angular acceleration and output angular velocity with a short time constant of ≈4.5 s. This output is prolonged by a central integrative network, velocity storage that lengthens the time constants of eye velocity. This mechanism utilizes canal, otolith, and visual (optokinetic) infor...

journal_title：Frontiers in neurology

authors： Yakushin SB,Raphan T,Cohen B

更新日期：2017-08-16 00:00:00

abstract：:Study Objectives: To clarify the effects of sleep duration on stroke and stroke subtypes, we adopted a Mendelian randomization (MR) approach to evaluate their causal relationship. Methods: A genome-wide association study including 446,118 participants from UK biobank was used to identify instruments for short sleep, l...

journal_title：Frontiers in neurology

authors： Lu H,Wu PF,Li RZ,Zhang W,Huang GX

更新日期：2020-10-07 00:00:00

abstract：:Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation. Connexin 43 (Cx43...

journal_title：Frontiers in neurology

authors： Liang Z,Wang X,Hao Y,Qiu L,Lou Y,Zhang Y,Ma D,Feng J

更新日期：2020-07-31 00:00:00

abstract：:Background:Candida dubliniensis is closely related to Candida albicans and rarely isolated in clinical specimens. C. dubliniensis is increasingly recognized as a pathogen in immunocompromised hosts. We present the third known case of Candida dubliniensis meningitis in a young immunocompetent host. Case Presentation: A...

journal_title：Frontiers in neurology

authors： Tahir M,Peseski AM,Jordan SJ

更新日期：2020-12-08 00:00:00

abstract：:Motion perception following rotational vestibular stimulation is described either as a self-motion or as an environmental-motion. The purpose of the present study was to establish frequency of occurrence of both sensations in healthy humans; what other sensations they experience and how factors insinuation and visual ...

journal_title：Frontiers in neurology

authors： Kolev OI

更新日期：2019-02-27 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities. ADPKD is caused by mutations in either PKD1 or PKD2 genes that encode for integral membrane proteins Polycystin-1 (PC1) and Polycystin-2 (PC2), respectively. Ex...

journal_title：Frontiers in neurology

authors： Thomas C,Zühlsdorf A,Hörtnagel K,Mulahasanovic L,Grauer OM,Kümpers P,Wiendl H,Meuth SG

更新日期：2018-05-25 00:00:00

abstract：:Introduction: Although patients with Parkinson's disease (PD) often suffer from oropharyngeal dysphagia, knowledge about the underlying pathophysiological mechanisms is limited. Substance P (SP) is a localization-independent neurotransmitter of the entire nervous system. Reduced levels of SP were found in saliva of pa...

journal_title：Frontiers in neurology

authors： Schröder JB,Marian T,Claus I,Muhle P,Pawlowski M,Wiendl H,Suntrup-Krueger S,Meuth SG,Dziewas R,Ruck T,Warnecke T

更新日期：2019-04-16 00:00:00

abstract：:Background and Objective: Parkinson disease (PD) with rapid eye movement (REM) sleep behavior disorder (PD-RBD) tend to be a distinct phenotype with more severe clinical characteristics and pathological lesion when compared with PD without RBD (PD-nRBD). However, the pathological mechanism underlying PD-RBD remains un...

journal_title：Frontiers in neurology

authors： Li J,Zeng Q,Zhou W,Zhai X,Lai C,Zhu J,Dong S,Lin Z,Cheng G

更新日期：2020-10-27 00:00:00