Changes over Time in IgE Sensitization to Allergens of the Fish Parasite Anisakis spp.

abstract：BACKGROUND:Leptospirosis is a neglected zoonosis affecting animals and humans caused by infection with Leptospira. The bacteria can survive outside of hosts for long periods of time in soil and water. While identification of Leptospira species from human cases and animal reservoirs are increasingly reported, little is ...

journal_title：PLoS neglected tropical diseases

authors： Mason MR,Encina C,Sreevatsan S,Muñoz-Zanzi C

更新日期：2016-08-16 00:00:00

abstract：:Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious blinding disease worldwide. Chronic conjunctival inflammation develops in childhood and leads to eyelid scarring and blindness in adulthood. The immune response to Ct provides only partial protection against re-infection, which can be frequent. ...

journal_title：PLoS neglected tropical diseases

authors： Hu VH,Holland MJ,Burton MJ

更新日期：2013-01-01 00:00:00

abstract：:Strongyloidiasis is a much-neglected but sometimes fatal soil born helminthiasis. The causing agent, the small intestinal parasitic nematode Strongyloides stercoralis can reproduce sexually through the indirect/heterogonic life cycle, or asexually through the auto-infective or the direct/homogonic life cycles. Usually...

journal_title：PLoS neglected tropical diseases

authors： Zhou S,Fu X,Pei P,Kucka M,Liu J,Tang L,Zhan T,He S,Chan YF,Rödelsperger C,Liu D,Streit A

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Dog rabies annually causes 24,000-70,000 deaths globally. We built a spreadsheet tool, RabiesEcon, to aid public health officials to estimate the cost-effectiveness of dog rabies vaccination programs in East Africa. METHODS:RabiesEcon uses a mathematical model of dog-dog and dog-human rabies transmission to...

journal_title：PLoS neglected tropical diseases

authors： Borse RH,Atkins CY,Gambhir M,Undurraga EA,Blanton JD,Kahn EB,Dyer JL,Rupprecht CE,Meltzer MI

更新日期：2018-05-23 00:00:00

abstract：BACKGROUND:Vector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and vector control, however, much less is known about the burden of ...

journal_title：PLoS neglected tropical diseases

authors： Alroy KA,Huang C,Gilman RH,Quispe-Machaca VR,Marks MA,Ancca-Juarez J,Hillyard M,Verastegui M,Sanchez G,Cabrera L,Vidal E,Billig EM,Cama VA,Náquira C,Bern C,Levy MZ,Working Group on Chagas Disease in Peru.

更新日期：2015-05-22 00:00:00

abstract：BACKGROUND:Pathogenesis of severe fever with thrombocytopenia syndrome (SFTS) has not been well described yet. Recent studies indicate that SFTSV could replicate in endothelial cells. Here we performed a case-control study to determine whether endothelial activation/dysfunction occurred in SFTSV infection and to identi...

journal_title：PLoS neglected tropical diseases

authors： Li XK,Yang ZD,Du J,Xing B,Cui N,Zhang PH,Li H,Zhang XA,Lu QB,Liu W

更新日期：2017-08-14 00:00:00

abstract：BACKGROUND:China has the highest incidence of hemorrhagic fever with renal syndrome (HFRS) worldwide. Reported cases account for 90% of the total number of global cases. By 2010, approximately 1.4 million HFRS cases had been reported in China. This study aimed to explore the effect of the rodent reservoir, and natural ...

journal_title：PLoS neglected tropical diseases

authors： Xiao H,Tian HY,Gao LD,Liu HN,Duan LS,Basta N,Cazelles B,Li XJ,Lin XL,Wu HW,Chen BY,Yang HS,Xu B,Grenfell B

更新日期：2014-01-09 00:00:00

abstract：BACKGROUND:Increased vascular permeability is a hallmark feature in severe dengue virus (DV) infection, and dysfunction of endothelial cells has been speculated to contribute in the pathogenesis of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Rho-family GTPase Rac1 is a significant element of endothelial b...

journal_title：PLoS neglected tropical diseases

authors： Wang JL,Zhang JL,Chen W,Xu XF,Gao N,Fan DY,An J

更新日期：2010-08-31 00:00:00

abstract：BACKGROUND:Paracoccidioidomycosis, a primary fungal infection restricted to Latin America, is acquired by inhalation of fungal particles. The immunoregulatory mechanisms that control the severe and mild forms of paracoccidioidomycosis are still unclear. Indoleamine 2,3-dioxygenase (IDO), an IFN-γ induced enzyme that ca...

journal_title：PLoS neglected tropical diseases

authors： Araújo EF,Loures FV,Bazan SB,Feriotti C,Pina A,Schanoski AS,Costa TA,Calich VL

更新日期：2014-11-20 00:00:00

abstract：:We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse ...

journal_title：PLoS neglected tropical diseases

authors： Morizot G,Jouffroy R,Faye A,Chabert P,Belhouari K,Calin R,Charlier C,Miailhes P,Siriez JY,Mouri O,Yera H,Gilquin J,Tubiana R,Lanternier F,Mamzer MF,Legendre C,Peyramond D,Caumes E,Lortholary O,Buffet P

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Sensitive diagnostic tools are required for an accurate assessment of prevalence and intensity of helminth infections in areas undergoing regular deworming, and for monitoring anthelmintic drug efficacy. We compared the diagnostic accuracy of the Kato-Katz and FLOTAC techniques in the frame of a drug efficac...

journal_title：PLoS neglected tropical diseases

authors： Knopp S,Speich B,Hattendorf J,Rinaldi L,Mohammed KA,Khamis IS,Mohammed AS,Albonico M,Rollinson D,Marti H,Cringoli G,Utzinger J

更新日期：2011-04-12 00:00:00

abstract：BACKGROUND:Zika (ZIKV) and Chikungunya (CHIKV) viruses are emerging Aedes-borne viruses that are spreading outside their known geographic range and causing wide-scale epidemics. It has been reported that these viruses can be transmitted efficiently by Ae. aegypti. Recent studies have shown that Ae. aegypti when transin...

journal_title：PLoS neglected tropical diseases

authors： Tan CH,Wong PJ,Li MI,Yang H,Ng LC,O'Neill SL

更新日期：2017-05-19 00:00:00

abstract：:Kinetoplastids are a group of parasites that includes several medically-important species. These human-infective species are transmitted by insect vectors in which the parasites undergo specific developmental transformations. For each species, this includes a stage in which parasites adhere to insect tissue via a hemi...

journal_title：PLoS neglected tropical diseases

authors： Filosa JN,Berry CT,Ruthel G,Beverley SM,Warren WC,Tomlinson C,Myler PJ,Dudkin EA,Povelones ML,Povelones M

更新日期：2019-07-29 00:00:00

abstract：BACKGROUND:Lymphatic filariasis (LF), a global public health problem affecting approximately 120 million people worldwide, is a leading cause of disability in the developing world including the South Pacific. Despite decades of ongoing mass drug administration (MDA) in the region, some island nations have not yet achie...

journal_title：PLoS neglected tropical diseases

authors： Chambers EW,Hapairai L,Peel BA,Bossin H,Dobson SL

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Contacts of leprosy patients are at increased risk of developing leprosy and need to be targeted for early diagnosis. Seropositivity to the phenolic glycolipid I (PGL-I) antigen of Mycobacterium leprae has been used to identify contacts who have an increased risk of developing leprosy. In the present study, ...

journal_title：PLoS neglected tropical diseases

authors： Düppre NC,Camacho LA,Sales AM,Illarramendi X,Nery JA,Sampaio EP,Sarno EN,Bührer-Sékula S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Close to 800 million people in the world are at risk of schistosomiasis, 85 per cent of whom live in Africa. Recent studies have indicated that female genital schistosomiasis might increase the risk of human immunodeficiency virus (HIV) infection. The aim of this study is to quantify and analyse the characte...

journal_title：PLoS neglected tropical diseases

authors： Jourdan PM,Roald B,Poggensee G,Gundersen SG,Kjetland EF

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Loiasis, a filarial infection caused by Loa loa usually thought to cause relatively minor morbidity, can cause serious and often fatal reactions in patients carrying very high levels of circulating Loa loa microfilariae (mf) following administration of microfilaricidal drugs. An experimental model of this co...

journal_title：PLoS neglected tropical diseases

authors： Wanji S,Eyong EE,Tendongfor N,Ngwa C,Esuka E,Kengne-Ouafo A,Datchoua-Poutcheu F,Enyong P,Hopkins A,Mackenzie CD

更新日期：2015-11-10 00:00:00

abstract：:The massive flood in Malaysia's east coast in December 2014 has placed Kelantan in a possible dengue outbreak risk. At this point, community awareness is essential in preventing disease spread. However, no data on knowledge, attitude, and practice (KAP) of dengue in Kelantan have existed in relevance to flood disaster...

journal_title：PLoS neglected tropical diseases

authors： AhbiRami R,Zuharah WF

更新日期：2020-03-27 00:00:00

abstract：:[This corrects the article DOI: 10.1371/journal.pntd.0005006.]. ...

journal_title：PLoS neglected tropical diseases

authors： Tadesse G

更新日期：2016-12-20 00:00:00

abstract：INTRODUCTION:Plasmodium knowlesi is now recognised as a leading cause of malaria in Malaysia. As humans come into increasing contact with the reservoir host (long-tailed macaques) as a consequence of deforestation, assessing the potential for a shift from zoonotic to sustained P. knowlesi transmission between humans is...

journal_title：PLoS neglected tropical diseases

authors： Imai N,White MT,Ghani AC,Drakeley CJ

更新日期：2014-07-24 00:00:00

abstract：:Helminth parasites are an assemblage of two major phyla of nematodes (also known as roundworms) and platyhelminths (also called flatworms). These parasites are a major human health burden, and infections caused by helminths are considered under neglected tropical diseases (NTDs). These infections are typified by limit...

journal_title：PLoS neglected tropical diseases

authors： Sharma A,Sharma M,Yogavel M,Sharma A

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Group 2 Innate lymphoid cells (ILC2s) are innate cells that produce the TH2 cytokines IL-5 and IL-13. The importance of these cells has recently been demonstrated in experimental models of parasitic diseases but there is a paucity of data on ILC2s in the context of human parasitic infections and in particula...

journal_title：PLoS neglected tropical diseases

authors： Nausch N,Appleby LJ,Sparks AM,Midzi N,Mduluza T,Mutapi F

更新日期：2015-03-23 00:00:00

abstract：BACKGROUND:Rhinoentomophthoromycosis, or rhino-facial conidiobolomycosis, is a rare, grossly disfiguring disease due to an infection with entomophthoralean fungi. We report a case of rhinoentomophthoromycosis from Gabon and suggest a staging system, which provides information on the prognosis and duration of antifungal...

journal_title：PLoS neglected tropical diseases

authors： Blumentrath CG,Grobusch MP,Matsiégui PB,Pahlke F,Zoleko-Manego R,Nzenze-Aféne S,Mabicka B,Sanguinetti M,Kremsner PG,Schaumburg F

更新日期：2015-10-01 00:00:00

abstract：:Mycobacterium tuberculosis complex (MTBC) comprises closely related species responsible for human and animal tuberculosis (TB). Efficient species determination is useful for epidemiological purposes, especially for the elucidation of the zoonotic contribution. In Algeria, data on MTBC genotypes are largely unknown. In...

journal_title：PLoS neglected tropical diseases

authors： Damene H,Tahir D,Diels M,Berber A,Sahraoui N,Rigouts L

更新日期：2020-11-30 00:00:00

abstract：:Mycetoma, one of the badly neglected tropical diseases, it is a localised chronic granulomatous inflammatory disease characterised by painless subcutaneous mass and formation of multiple sinuses that produce purulent discharge and grains. If untreated early and appropriately, it usually spread to affect the deep struc...

journal_title：PLoS neglected tropical diseases

authors： Bakhiet SM,Fahal AH,Musa AM,Mohamed ESW,Omer RF,Ahmed ES,El Nour M,Mustafa ERM,Sheikh A Rahman ME,Suliman SH,El Mamoun MAG,El Amin HM

更新日期：2018-05-10 00:00:00

abstract：:Control of arbovirus transmission remains focused on vector control through application of insecticides directly to the environment. However, these insecticide applications are often reactive interventions that can be poorly-targeted, inadequate for localized control during outbreaks, and opposed due to environmental ...

journal_title：PLoS neglected tropical diseases

authors： Nguyen C,Gray M,Burton TA,Foy SL,Foster JR,Gendernalik AL,Rückert C,Alout H,Young MC,Boze B,Ebel GD,Clapsaddle B,Foy BD

更新日期：2019-03-07 00:00:00

abstract：:Dengue fever (DEN) is the most common arboviral disease in the world and dengue virus (DENV) causes 390 million annual infections around the world, of which 240 million are inapparent and 96 million are symptomatic. During the past decade a changing epidemiological pattern has been observed in Africa, with DEN outbrea...

journal_title：PLoS neglected tropical diseases

authors： Gaye A,Wang E,Vasilakis N,Guzman H,Diallo D,Talla C,Ba Y,Dia I,Weaver SC,Diallo M

更新日期：2019-02-13 00:00:00

abstract：BACKGROUND:The control of neglected tropical diseases (NTDs) has primarily focused on preventive chemotherapy and case management. Less attention has been placed on the role of ensuring access to adequate water, sanitation, and hygiene and personal preventive measures in reducing exposure to infection. Our aim was to a...

journal_title：PLoS neglected tropical diseases

authors： Tomczyk S,Deribe K,Brooker SJ,Clark H,Rafique K,Knopp S,Utzinger J,Davey G

更新日期：2014-11-13 00:00:00

abstract：INTRODUCTION:Neglected tropical diseases produce an enormous burden on many of the poorest and most disenfranchised populations in sub-Saharan Africa. Similar to other developing areas throughout the world, this region's dearth of skilled health providers renders Western-style primary care efforts to address such disea...

journal_title：PLoS neglected tropical diseases

authors： Corley AG,Thornton CP,Glass NE

更新日期：2016-09-15 00:00:00

abstract：:The East/Central/South African genotype of Chikungunya virus with the E1-A226V mutation emerged in 2011 in Cambodia and spread in 2012. An outbreak of 190 cases was documented in Trapeang Roka, a rural village. We surveyed 425 village residents within 3-4 weeks after the outbreak, and determined the sensitivity and sp...

journal_title：PLoS neglected tropical diseases

authors： Galatas B,Ly S,Duong V,Baisley K,Nguon K,Chan S,Huy R,Ly S,Sorn S,Som L,Buchy P,Tarantola A

更新日期：2016-01-11 00:00:00