Exposure to Sevoflurane Affects the Development of Parvalbumin Interneurons in the Main Olfactory Bulb in Mice.

Abstract:

:Sevoflurane is widely used in adult and pediatric patients during clinical surgeries. Although studies have shown that exposure to sevoflurane impairs solfactory memory after an operation, the neuropathological changes underlying this effect are not clear. This study detected the effect of sevoflurane exposure on the development of calcium-binding proteins-expressing interneurons in the main olfactory bulb (MOB). We exposed neonatal mice to 2% sevoflurane at two different developmental time points and found that exposing mice to sevoflurane at postnatal day (PD) 7 significantly decreased the expression of GAD67 and parvalbumin (PV) in the olfactory bulb (OB) but did not alter the expression of calretinin (CR) or calbindin D28k (CB). The number and dendritic morphology of PV-expressing interneurons in the MOB were impaired by exposure to sevoflurane at PD7. However, exposure to sevoflurane at PD10 had no effect on calcium-binding protein expression or the number and dendritic morphology of PV-expressing interneurons in the MOB. These results suggest that exposing neonatal mice to sevoflurane during a critical period of olfactory development affects the development of PV-expressing interneurons in the MOB.

journal_name

Front Neuroanat

authors

Yang J,Chen J,Cai G,Lu R,Sun T,Luo T,Wu S,Ling S

doi

10.3389/fnana.2016.00072

subject

Has Abstract

pub_date

2016-06-24 00:00:00

pages

72

issn

1662-5129

journal_volume

10

pub_type

杂志文章
  • Optimization of 3D-Visualization of Micro-Anatomical Structures of the Human Inner Ear in Osmium Tetroxide Contrast Enhanced Micro-CT Scans.

    abstract::Introduction: Knowledge of the neuro-anatomical architecture of the inner ear contributes to the improvement and development of cochlear and vestibular implants. The present knowledge is mainly based on two-dimensional images (histology) or derived models that simplify the complexity of this architecture. This study i...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00041

    authors: van den Boogert T,van Hoof M,Handschuh S,Glueckert R,Guinand N,Guyot JP,Kingma H,Perez-Fornos A,Seppen B,Johnson Chacko L,Schrott-Fischer A,van de Berg R

    更新日期:2018-05-22 00:00:00

  • Distribution of vasotocin- and vasoactive intestinal peptide-like immunoreactivity in the brain of blue tit (Cyanistes coeruleus).

    abstract::Blue tits (Cyanistes coeruleus) are songbirds, used as model animals in numerous studies covering a wide field of research. Nevertheless, the distribution of neuropeptides in the brain of this avian species remains largely unknown. Here we present some of the first results on distribution of Vasotocine (AVT) and Vasoa...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00090

    authors: Montagnese CM,Székely T,Csillag A,Zachar G

    更新日期:2015-07-14 00:00:00

  • Functional connectivity estimation over large networks at cellular resolution based on electrophysiological recordings and structural prior.

    abstract::Despite many structural and functional aspects of the brain organization have been extensively studied in neuroscience, we are still far from a clear understanding of the intricate structure-function interactions occurring in the multi-layered brain architecture, where billions of different neurons are involved. Altho...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2014.00137

    authors: Ullo S,Nieus TR,Sona D,Maccione A,Berdondini L,Murino V

    更新日期:2014-11-20 00:00:00

  • Neocortical development as an evolutionary platform for intragenomic conflict.

    abstract::Embryonic development in mammals has evolved a platform for genomic conflict between mothers and embryos and, by extension, between maternal and paternal genomes. The evolutionary interests of the mother and embryo may be maximized through the promotion of sex-chromosome genes and imprinted alleles, resulting in the r...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00002

    authors: Lewitus E,Kalinka AT

    更新日期:2013-04-09 00:00:00

  • Structural Covariance Changes of Anterior and Posterior Hippocampus During Musical Training in Young Adults.

    abstract::Musical training can induce the functional and structural changes of the hippocampus. The hippocampus is not a homogeneous structure which can be divided into anterior and posterior parts along its longitudinal axis, and the whole-brain structural covariances of anterior (aHC) and posterior hippocampus (pHC) show dist...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2020.00020

    authors: Guo P,Li Q,Wang X,Li X,Wang S,Xie Y,Xie Y,Fu Z,Zhang X,Li S

    更新日期:2020-05-19 00:00:00

  • Whole Brain Imaging with Serial Two-Photon Tomography.

    abstract::Imaging entire mouse brains at submicron resolution has historically been a challenging undertaking and largely confined to the province of dedicated atlasing initiatives. This has limited systematic investigations into important areas of neuroscience, such as neural circuits, brain mapping and neurodegeneration. In t...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2016.00031

    authors: Amato SP,Pan F,Schwartz J,Ragan TM

    更新日期:2016-03-22 00:00:00

  • The Dual Nature of Onuf's Nucleus: Neuroanatomical Features and Peculiarities, in Health and Disease.

    abstract::Onuf's nucleus is a small group of neurons located in the ventral horns of the sacral spinal cord. The motor neurons (MNs) of Onuf's nucleus innervate striated voluntary muscles of the pelvic floor and are histologically and biochemically comparable to the other somatic spinal MNs. However, curiously, these neurons al...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2020.572013

    authors: Schellino R,Boido M,Vercelli A

    更新日期:2020-09-04 00:00:00

  • Sexual activity increases the number of newborn cells in the accessory olfactory bulb of male rats.

    abstract::In rodents, sexual behavior depends on the adequate detection of sexually relevant stimuli. The olfactory bulb (OB) is a region of the adult mammalian brain undergoing constant cell renewal by continuous integration of new granular and periglomerular neurons in the accessory (AOB) and main (MOB) olfactory bulbs. The p...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2012.00025

    authors: Portillo W,Unda N,Camacho FJ,Sánchez M,Corona R,Arzate DM,Díaz NF,Paredes RG

    更新日期:2012-07-06 00:00:00

  • Brain damages in ketamine addicts as revealed by magnetic resonance imaging.

    abstract::Ketamine, a known antagonist of N-methyl-D-aspartic (NMDA) glutamate receptors, had been used as an anesthetic particularly for pediatric or for cardiac patients. Unfortunately, ketamine has become an abusive drug in many parts of the world while chronic and prolonged usage led to damages of many organs including the ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00023

    authors: Wang C,Zheng D,Xu J,Lam W,Yew DT

    更新日期:2013-07-17 00:00:00

  • A comparison of manual neuronal reconstruction from biocytin histology or 2-photon imaging: morphometry and computer modeling.

    abstract::Accurate 3D reconstruction of neurons is vital for applications linking anatomy and physiology. Reconstructions are typically created using Neurolucida after biocytin histology (BH). An alternative inexpensive and fast method is to use freeware such as Neuromantic to reconstruct from fluorescence imaging (FI) stacks a...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2014.00065

    authors: Blackman AV,Grabuschnig S,Legenstein R,Sjöström PJ

    更新日期:2014-07-11 00:00:00

  • Axonal Segregation and Role of the Vesicular Glutamate Transporter VGLUT3 in Serotonin Neurons.

    abstract::A subset of monoamine neurons releases glutamate as a cotransmitter due to presence of the vesicular glutamate transporters VGLUT2 or VGLUT3. In addition to mediating vesicular loading of glutamate, it has been proposed that VGLUT3 enhances serotonin (5-HT) vesicular loading by the vesicular monoamine transporter (VMA...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2016.00039

    authors: Voisin AN,Mnie-Filali O,Giguère N,Fortin GM,Vigneault E,El Mestikawy S,Descarries L,Trudeau LÉ

    更新日期:2016-04-12 00:00:00

  • Comparative gene expression analysis among vocal learners (bengalese finch and budgerigar) and non-learners (quail and ring dove) reveals variable cadherin expressions in the vocal system.

    abstract::Birds use various vocalizations to communicate with one another, and some are acquired through learning. So far, three families of birds (songbirds, parrots, and hummingbirds) have been identified as having vocal learning ability. Previously, we found that cadherins, a large family of cell-adhesion molecules, show voc...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00028

    authors: Matsunaga E,Okanoya K

    更新日期:2011-04-20 00:00:00

  • Perinatal asphyxia results in altered expression of the hippocampal acylethanolamide/endocannabinoid signaling system associated to memory impairments in postweaned rats.

    abstract::Perinatal asphyxia (PA) is an obstetric complication that strongly affects the CNS. The endocannabinoid system (ECS) is a lipid transmitter system involved in several physiological processes including synaptic plasticity, neurogenesis, memory, and mood. Endocannabinoids, and other acylethanolamides (AEs) without endoc...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00141

    authors: Blanco E,Galeano P,Holubiec MI,Romero JI,Logica T,Rivera P,Pavón FJ,Suarez J,Capani F,Rodríguez de Fonseca F

    更新日期:2015-11-03 00:00:00

  • Laminar Distribution of Subsets of GABAergic Axon Terminals in Human Prefrontal Cortex.

    abstract::In human prefrontal cortex (PFC), ~85% of γ-aminobutyric acid (GABA)-expressing neurons can be subdivided into non-overlapping groups by the presence of calbindin (CB), calretinin (CR) or parvalbumin (PV). Substantial research has focused on the differences in the laminar locations of the cells bodies of these neurons...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2018.00009

    authors: Fish KN,Rocco BR,Lewis DA

    更新日期:2018-02-16 00:00:00

  • Barriers in the brain: resolving dendritic spine morphology and compartmentalization.

    abstract::Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has been hypothesized to confine biochemical and electric signals within...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2014.00142

    authors: Adrian M,Kusters R,Wierenga CJ,Storm C,Hoogenraad CC,Kapitein LC

    更新日期:2014-12-04 00:00:00

  • SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic Neurons.

    abstract::Subsets of GABAergic neurons are able to maintain high frequency discharge patterns, which requires efficient replenishment of the releasable pool of GABA. Although glutamine is considered a preferred precursor of GABA, the identity of transporters involved in glutamine uptake by GABAergic neurons remains elusive. Mol...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/neuro.05.001.2010

    authors: Solbu TT,Bjørkmo M,Berghuis P,Harkany T,Chaudhry FA

    更新日期:2010-02-08 00:00:00

  • Brain scaling in mammalian evolution as a consequence of concerted and mosaic changes in numbers of neurons and average neuronal cell size.

    abstract::Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2014.00077

    authors: Herculano-Houzel S,Manger PR,Kaas JH

    更新日期:2014-08-11 00:00:00

  • Cellular and molecular basis of cerebellar development.

    abstract::Historically, the molecular and cellular mechanisms of cerebellar development were investigated through structural descriptions and studying spontaneous mutations in animal models and humans. Advances in experimental embryology, genetic engineering, and neuroimaging techniques render today the possibility to approach ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00018

    authors: Martinez S,Andreu A,Mecklenburg N,Echevarria D

    更新日期:2013-06-26 00:00:00

  • A stereological study of synapse number in the epileptic human hippocampus.

    abstract::Hippocampal sclerosis is the most frequent pathology encountered in resected mesial temporal structures from patients with intractable temporal lobe epilepsy (TLE). Here, we have used stereological methods to compare the overall density of synapses and neurons between non-sclerotic and sclerotic hippocampal tissue obt...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00008

    authors: Alonso-Nanclares L,Kastanauskaite A,Rodriguez JR,Gonzalez-Soriano J,Defelipe J

    更新日期:2011-02-24 00:00:00

  • Distribution of 28 kDa Calbindin-Immunopositive Neurons in the Cat Spinal Cord.

    abstract::The distribution of vitamin D-dependent calcium-binding protein (28 kDa calbindin) was investigated in cat lumbar and sacral spinal cord segments (L1-S3). We observed specific multi-dimensional distributions over the spinal segments for small immunopositive cells in Rexed laminae II-III and medium-to-large cells of va...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00166

    authors: Merkulyeva N,Veshchitskii A,Makarov F,Gerasimenko Y,Musienko P

    更新日期:2016-01-28 00:00:00

  • Ontogenesis of NADPH-diaphorase positive neurons in guinea pig neocortex.

    abstract::In mammalian cerebrum there exist two distinct types of interneurons expressing nitric oxide synthase (NOS). Type I neurons are large in size and exhibit heavy nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) histochemical reaction, while type II cells are small with light NADPH-d reactivity. The time ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2015.00011

    authors: Liu C,Yang Y,Hu X,Li JM,Zhang XM,Cai Y,Li Z,Yan XX

    更新日期:2015-02-16 00:00:00

  • Hypothesis on the dual origin of the Mammalian subplate.

    abstract::The development of the mammalian neocortex relies heavily on subplate. The proportion of this cell population varies considerably in different mammalian species. Subplate is almost undetectable in marsupials, forms a thin, but distinct layer in mouse and rat, a larger layer in carnivores and big-brained mammals as pig...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2011.00025

    authors: Montiel JF,Wang WZ,Oeschger FM,Hoerder-Suabedissen A,Tung WL,García-Moreno F,Holm IE,Villalón A,Molnár Z

    更新日期:2011-04-07 00:00:00

  • Histochemical characterization, distribution and morphometric analysis of NADPH diaphorase neurons in the spinal cord of the agouti.

    abstract::We evaluated the neuropil distribution of the enzymes NADPH diaphorase (NADPH-d) and cytochrome oxidase (CO) in the spinal cord of the agouti, a medium-sized diurnal rodent, together with the distribution pattern and morphometrical characteristics of NADPH-d reactive neurons across different spinal segments. Neuropil ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/neuro.05.002.2008

    authors: Freire MA,Tourinho SC,Guimarães JS,Oliveira JL,Picanço-Diniz CW,Gomes-Leal W,Pereira A

    更新日期:2008-05-26 00:00:00

  • Dogs Have the Most Neurons, Though Not the Largest Brain: Trade-Off between Body Mass and Number of Neurons in the Cerebral Cortex of Large Carnivoran Species.

    abstract::Carnivorans are a diverse group of mammals that includes carnivorous, omnivorous and herbivorous, domesticated and wild species, with a large range of brain sizes. Carnivory is one of several factors expected to be cognitively demanding for carnivorans due to a requirement to outsmart larger prey. On the other hand, l...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2017.00118

    authors: Jardim-Messeder D,Lambert K,Noctor S,Pestana FM,de Castro Leal ME,Bertelsen MF,Alagaili AN,Mohammad OB,Manger PR,Herculano-Houzel S

    更新日期:2017-12-12 00:00:00

  • Comparative Distribution of Relaxin-3 Inputs and Calcium-Binding Protein-Positive Neurons in Rat Amygdala.

    abstract::The neural circuits involved in mediating complex behaviors are being rapidly elucidated using various newly developed and powerful anatomical and molecular techniques, providing insights into the neural basis for anxiety disorders, depression, addiction, and dysfunctional social behaviors. Many of these behaviors and...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2016.00036

    authors: Santos FN,Pereira CW,Sánchez-Pérez AM,Otero-García M,Ma S,Gundlach AL,Olucha-Bordonau FE

    更新日期:2016-04-07 00:00:00

  • Parkinson's disease: animal models and dopaminergic cell vulnerability.

    abstract::Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, the pathogenesis of PD re...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章,评审

    doi:10.3389/fnana.2014.00155

    authors: Blesa J,Przedborski S

    更新日期:2014-12-15 00:00:00

  • Neuronize: a tool for building realistic neuronal cell morphologies.

    abstract::This study presents a tool, Neuronize, for building realistic three-dimensional models of neuronal cells from the morphological information extracted through computer-aided tracing applications. Neuronize consists of a set of methods designed to build 3D neural meshes that approximate the cell membrane at different re...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2013.00015

    authors: Brito JP,Mata S,Bayona S,Pastor L,Defelipe J,Benavides-Piccione R

    更新日期:2013-06-03 00:00:00

  • Fast 3-D Imaging of Brain Organoids With a New Single-Objective Planar-Illumination Two-Photon Microscope.

    abstract::Human inducible pluripotent stem cells (hiPSCs) hold a large potential for disease modeling. hiPSC-derived human astrocyte and neuronal cultures permit investigations of neural signaling pathways with subcellular resolution. Combinatorial cultures, and three-dimensional (3-D) embryonic bodies (EBs) enlarge the scope o...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2019.00077

    authors: Rakotoson I,Delhomme B,Djian P,Deeg A,Brunstein M,Seebacher C,Uhl R,Ricard C,Oheim M

    更新日期:2019-08-20 00:00:00

  • An In vivo Multi-Modal Structural Template for Neonatal Piglets Using High Angular Resolution and Population-Based Whole-Brain Tractography.

    abstract::An increasing number of applications use the postnatal piglet model in neuroimaging studies, however, these are based primarily on T1 weighted image templates. There is a growing need for a multimodal structural brain template for a comprehensive depiction of the piglet brain, particularly given the growing applicatio...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2016.00092

    authors: Zhong J,Chen DQ,Walker M,Waspe A,Looi T,Piorkowska K,Drake JM,Hodaie M

    更新日期:2016-09-27 00:00:00

  • How the cortex gets its folds: an inside-out, connectivity-driven model for the scaling of Mammalian cortical folding.

    abstract::Larger mammalian cerebral cortices tend to have increasingly folded surfaces, often considered to result from the lateral expansion of the gray matter (GM), which, in a volume constrained by the cranium, causes mechanical compression that is relieved by inward folding of the white matter (WM), or to result from differ...

    journal_title:Frontiers in neuroanatomy

    pub_type: 杂志文章

    doi:10.3389/fnana.2012.00003

    authors: Mota B,Herculano-Houzel S

    更新日期:2012-02-02 00:00:00