GluN2B-Containg NMDA Receptors on Adult-Born Granule Cells Contribute to the Antidepressant Action of Fluoxetine.

abstract：:Alzheimer's disease (AD) is associated with degeneration of cholinergic neurons in the basal forebrain. Administration of the immunotoxin 192IgG-saporin to rats, an animal model of AD, leads to degeneration of cholinergic neurons in the medial septal area. In the present study, cholinergic cell death was induced by in...

journal_title：Frontiers in neuroscience

authors： Dobryakova YV,Volobueva MN,Manolova AO,Medvedeva TM,Kvichansky AA,Gulyaeva NV,Markevich VA,Stepanichev MY,Bolshakov AP

更新日期：2019-03-12 00:00:00

abstract：:There is increasing interest in understanding how the phase and amplitude of distinct neural oscillations might interact to support dynamic communication within the brain. In particular, previous work has demonstrated a coupling between the phase of low frequency oscillations and the amplitude (or power) of high frequ...

journal_title：Frontiers in neuroscience

authors： Seymour RA,Rippon G,Kessler K

更新日期：2017-09-01 00:00:00

abstract：:Circadian rhythms of behavior and physiology are generated by central and peripheral circadian oscillators entrained by periodic environmental or physiological stimuli. A master circadian pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) is directly entrained by daily light-dark (LD) cycles, and coordinates ...

journal_title：Frontiers in neuroscience

authors： Patton DF,Mistlberger RE

更新日期：2013-10-14 00:00:00

abstract：:Event-driven neuromorphic spiking sensors such as the silicon retina and the silicon cochlea encode the external sensory stimuli as asynchronous streams of spikes across different channels or pixels. Combining state-of-art deep neural networks with the asynchronous outputs of these sensors has produced encouraging res...

journal_title：Frontiers in neuroscience

authors： Anumula J,Neil D,Delbruck T,Liu SC

更新日期：2018-02-09 00:00:00

abstract：:Experiments often challenge the null hypothesis that an intervention, for instance application of non-invasive brain stimulation (NIBS), has no effect on an outcome measure. In conventional statistics, a positive result rejects that hypothesis, but a null result is meaningless. Informally, however, researchers often d...

journal_title：Frontiers in neuroscience

authors： de Graaf TA,Sack AT

更新日期：2018-12-11 00:00:00

abstract：:Stroke patients with severe motor deficits of the upper extremity may practice rehabilitation exercises with the assistance of a multi-joint exoskeleton. Although this technology enables intensive task-oriented training, it may also lead to slacking when the assistance is too supportive. Preserving the engagement of t...

journal_title：Frontiers in neuroscience

authors： Grimm F,Naros G,Gharabaghi A

更新日期：2016-11-15 00:00:00

abstract：:SpiNNaker is a digital neuromorphic architecture, designed specifically for the low power simulation of large-scale spiking neural networks at speeds close to biological real-time. Unlike other neuromorphic systems, SpiNNaker allows users to develop their own neuron and synapse models as well as specify arbitrary conn...

journal_title：Frontiers in neuroscience

authors： Mikaitis M,Pineda García G,Knight JC,Furber SB

更新日期：2018-02-27 00:00:00

abstract：:Neurologic Music Therapy (NMT) is a novel impairment-focused behavioral intervention system whose techniques are based on the clinical neuroscience of music perception, cognition, and production. Auditory Stimulation (RAS) is one of the NMT techniques, which aims to develop and maintain a physiological rhythmic motor ...

journal_title：Frontiers in neuroscience

authors： Buard I,Dewispelaere WB,Thaut M,Kluger BM

更新日期：2019-02-19 00:00:00

abstract：:Recent studies have identified the Drosophila brain circuits involved in the sleep/wake switch and have pointed to the modulation of neuronal excitability as one of the underlying mechanisms triggering sleep need. In this study we aimed to explore the link between the homeostatic regulation of neuronal excitability an...

journal_title：Frontiers in neuroscience

authors： De Jesús-Olmo LA,Rodríguez N,Francia M,Alemán-Rios J,Pacheco-Agosto CJ,Ortega-Torres J,Nieves R,Fuenzalida-Uribe N,Ghezzi A,Agosto JL

更新日期：2020-04-17 00:00:00

abstract：:For brain-computer interfaces (BCIs) that utilize visual cues to direct the user, the neural signals extracted by the computer are representative of ongoing processes, visual evoked responses, and voluntary modulation. We proposed to use three brain signatures for predicting success on a single trial of a BCI task. Th...

journal_title：Frontiers in neuroscience

authors： Geronimo A,Kamrunnahar M,Schiff SJ

更新日期：2016-04-26 00:00:00

abstract：:Although flight is regarded as a key behavior of birds this review argues that the perceptual demands for its control are met within constraints set by the perceptual demands of two other key tasks: the control of bill (or feet) position, and the detection of food items/predators. Control of bill position, or of the f...

journal_title：Frontiers in neuroscience

authors： Martin GR

更新日期：2017-11-07 00:00:00

abstract：:While the adult human brain has approximately 8.8 × 10(10) neurons, this number is dwarfed by its 1 × 10(15) synapses. From the point of view of neuromorphic engineering and neural simulation in general this makes the simulation of these synapses a particularly complex problem. SpiNNaker is a digital, neuromorphic arc...

journal_title：Frontiers in neuroscience

authors： Knight JC,Furber SB

更新日期：2016-09-14 00:00:00

abstract：Background:Endovascular treatment of large or giant non-saccular vertebrobasilar aneurysms (VBAs) by conventional stents is difficult and has unsatisfactory outcomes. Object:This study was performed to retrospectively analyze the safety and efficacy of a flow diverter in treating large and giant non-saccular VBAs. Me...

journal_title：Frontiers in neuroscience

authors： Wang J,Jia L,Duan Z,Wang Z,Yang X,Zhang Y,Lv M

更新日期：2019-11-28 00:00:00

abstract：:The ability to delegate control over repetitive tasks from higher to lower neural centers may be a fundamental innovation in human cognition. Plausibly, the massive neurocomputational challenges associated with the mastery of balance during the evolution of bipedality in proto-humans provided a strong selective advant...

journal_title：Frontiers in neuroscience

authors： Shine JM,Shine R

更新日期：2014-04-29 00:00:00

abstract：Objective:Although many studies have attempted to improve the performance of the visual-based P300-speller system, its performance is still not satisfactory. The current system has limitations for patients with neurodegenerative diseases, in which muscular control of the eyes may be impaired or deteriorate over time. S...

journal_title：Frontiers in neuroscience

authors： Lu Z,Li Q,Gao N,Yang J,Bai O

更新日期：2019-09-27 00:00:00

abstract：:Attention and working memory (WM) are core components of executive functions, and they can be enhanced by training. One activity that has shown to improve executive functions is musical training, but the brain networks underlying these improvements are not well known. We aimed to identify, using functional MRI (fMRI),...

journal_title：Frontiers in neuroscience

authors： Kausel L,Zamorano F,Billeke P,Sutherland ME,Larrain-Valenzuela J,Stecher X,Schlaug G,Aboitiz F

更新日期：2020-10-08 00:00:00

abstract：:Aggressive behavior is associated with dysfunctional frontolimbic emotion regulation circuits. Recent findings suggest serotonin as a primary transmitter for prefrontal amygdala control. However, the association between serotonin levels, amygdala regulation, and aggression is still a matter of debate. Neurobehavioral ...

journal_title：Frontiers in neuroscience

authors： Klasen M,Wolf D,Eisner PD,Eggermann T,Zerres K,Zepf FD,Weber R,Mathiak K

更新日期：2019-02-22 00:00:00

abstract：:The cocaine- and amphetamine-regulated transcript (CART) has been the subject of significant interest for over a decade. Work to decipher the detailed mechanism of CART function has been hampered by the lack of specific pharmacological tools like antagonists and the absence of a specific CART receptor(s). However, ext...

journal_title：Frontiers in neuroscience

authors： Lau J,Herzog H

更新日期：2014-10-13 00:00:00

abstract：:Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great potential for combating bacterial resistance. AMPs can be both bacteriostatic and bactericidal, induce rapid killing and display a lower propensity to develop resistance than do conventional antibiotics. Despite significant progres...

journal_title：Frontiers in neuroscience

authors： Li J,Koh JJ,Liu S,Lakshminarayanan R,Verma CS,Beuerman RW

更新日期：2017-02-14 00:00:00

abstract：:This paper presents a digital implementation of the Cascade of Asymmetric Resonators with Fast-Acting Compression (CAR-FAC) cochlear model. The CAR part simulates the basilar membrane's (BM) response to sound. The FAC part models the outer hair cell (OHC), the inner hair cell (IHC), and the medial olivocochlear effere...

journal_title：Frontiers in neuroscience

authors： Xu Y,Thakur CS,Singh RK,Hamilton TJ,Wang RM,van Schaik A

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Cortical modulation is likely to be involved in the various therapeutic effects of deep brain stimulation (DBS). However, it is currently difficult to predict the changes of cortical modulation during clinical adjustment of DBS. Therefore, we present a novel quantitative approach to estimate anatomical regio...

journal_title：Frontiers in neuroscience

authors： Hartmann CJ,Chaturvedi A,Lujan JL

更新日期：2015-02-10 00:00:00

abstract：:Dynamic Field Theory (DFT) is an established framework for modeling embodied cognition. In DFT, elementary cognitive functions such as memory formation, formation of grounded representations, attentional processes, decision making, adaptation, and learning emerge from neuronal dynamics. The basic computational element...

journal_title：Frontiers in neuroscience

authors： Sandamirskaya Y

更新日期：2014-01-22 00:00:00

abstract：:Ongoing brain activity has been implicated in the modulation of cortical excitability. The combination of electroencephalography (EEG) and transcranial magnetic stimulation (TMS) in a real-time triggered setup is a novel method for testing hypotheses about the relationship between spontaneous neuronal oscillations, co...

journal_title：Frontiers in neuroscience

authors： Schaworonkow N,Caldana Gordon P,Belardinelli P,Ziemann U,Bergmann TO,Zrenner C

更新日期：2018-12-13 00:00:00

abstract：:Intracortical electrodes for brain-machine interfaces rely on intimate contact with tissues for recording signals and stimulating neurons. However, the long-term viability of intracortical electrodes in vivo is poor, with a major contributing factor being the development of a glial scar. In vivo approaches for evaluat...

journal_title：Frontiers in neuroscience

authors： Gilmour A,Poole-Warren L,Green RA

更新日期：2019-12-17 00:00:00

abstract：:Magnetic resonance imaging (MRI) studies have highlighted subcortical, cortical, and structural connectivity abnormalities associated with attention-deficit/hyperactivity disorder (ADHD). Gyrification investigations of the cortex have been inconsistent and largely negative, potentially due to a lack of sensitivity of ...

journal_title：Frontiers in neuroscience

authors： Forde NJ,Ronan L,Zwiers MP,Alexander-Bloch AF,Faraone SV,Oosterlaan J,Heslenfeld DJ,Hartman CA,Buitelaar JK,Hoekstra PJ

更新日期：2017-04-20 00:00:00

abstract：Purpose:The aim of this study was to explore experiences of upper limb somatosensory discrimination retraining in persons with stroke. Methods:A qualitative methodology was used within the context of a randomized control trial of somatosensory retraining: the CoNNECT trial. Participants in the CoNNECT trial completed ...

journal_title：Frontiers in neuroscience

authors： Turville ML,Walker J,Blennerhassett JM,Carey LM

更新日期：2019-07-24 00:00:00

abstract：:Auditory recognition memory in non-human primates differs from recognition memory in other sensory systems. Monkeys learn the rule for visual and tactile delayed matching-to-sample within a few sessions, and then show one-trial recognition memory lasting 10-20 min. In contrast, monkeys require hundreds of sessions to ...

journal_title：Frontiers in neuroscience

authors： Muñoz-López M,Insausti R,Mohedano-Moriano A,Mishkin M,Saunders RC

更新日期：2015-05-18 00:00:00

abstract：:Blood-oxygen-level dependent (BOLD) signals are widely used in functional magnetic resonance imaging (fMRI) as a proxy measure of brain activation. However, because these signals are blood-related, they are also influenced by other physiological processes. This is especially true in resting state fMRI, during which no...

journal_title：Frontiers in neuroscience

authors： Tong Y,Hocke LM,Lindsey KP,Erdoğan SB,Vitaliano G,Caine CE,Frederick Bd

更新日期：2016-06-30 00:00:00

abstract：:Hypothalamic neurohormones are released in a pulsatile manner. The mechanisms of this pulsatility remain poorly understood and several hypotheses are available, depending upon the neuroendocrine system considered. Among these systems, hypothalamo-neurohypophyseal magnocellular neurons have been early-considered models...

journal_title：Frontiers in neuroscience

authors： Israel JM,Oliet SH,Ciofi P

更新日期：2016-03-31 00:00:00

abstract：:Over the past decade there has been a renaissance in our understanding of spinal cord circuits; new technologies are beginning to provide key insights into descending circuits which project onto spinal cord central pattern generators. By integrating work from both the locomotor and animal behavioral fields, we can now...

journal_title：Frontiers in neuroscience

authors： Kim LH,Sharma S,Sharples SA,Mayr KA,Kwok CHT,Whelan PJ

更新日期：2017-10-18 00:00:00