Abstract:
:Genetic studies using model organisms have shown that many long-lived mutants display impaired fitness, such as reduced fecundity and delayed development. However, in several wild animals, the association between longevity and fitness does not seem to be inevitable. Thus, the relationship between longevity and fitness in wild organisms remains inconclusive. Here, we determined the correlation between lifespan and fitness, developmental rate and brood size, by using 16 wild-derived C. elegans strains originated from various geographic areas. We found a negative correlation between lifespan and developmental rate. In contrast, we did not find such negative correlation between longevity and developmental rate among the individuals of C. elegans strains. These data imply that polymorphic genetic variants among wild isolates determine resource allocation to longevity and developmental rate.
journal_name
Aging (Albany NY)journal_title
Agingauthors
Lee Y,Hwang W,Jung J,Park S,Cabatbat JJ,Kim PJ,Lee SJdoi
10.18632/aging.100960subject
Has Abstractpub_date
2016-05-01 00:00:00pages
986-99issue
5issn
1945-4589pii
100960journal_volume
8pub_type
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