Mixed Effects Models for Resampled Network Statistics Improves Statistical Power to Find Differences in Multi-Subject Functional Connectivity.

abstract：:Protein tyrosine phosphatases (PTPs) are important regulators of intracellular signaling pathways via the dephosphorylation of phosphotyrosyl residues on various receptor and non-receptor substrates. The phosphorylation state of central nervous system (CNS) signaling components underlies the molecular mechanisms of a ...

journal_title：Frontiers in neuroscience

authors： Tsou RC,Bence KK

更新日期：2013-01-07 00:00:00

abstract：:The sliding-window-based dynamic functional connectivity networks (D-FCNs) derived from resting-state functional magnetic resonance imaging (rs-fMRI) are effective methods for diagnosing various neurological diseases, including autism spectrum disorder (ASD). However, traditional D-FCNs are low-order networks based on...

journal_title：Frontiers in neuroscience

authors： Zhao F,Chen Z,Rekik I,Lee SW,Shen D

更新日期：2020-04-28 00:00:00

abstract：:Heterogeneity between late-onset Parkinson's disease (LOPD) and early-onset Parkinson's disease (EOPD) is mainly reflected in the following aspects including genetics, disease progression, drug response, clinical manifestation, and neuropathological change. Although many studies have investigated these differences in ...

journal_title：Frontiers in neuroscience

authors： Yue Y,Jiang Y,Shen T,Pu J,Lai HY,Zhang B

更新日期：2020-02-25 00:00:00

abstract：:Decades of research dedicated toward Alzheimer's disease (AD) has culminated in much of the current understanding of the neurodegeneration associated with disease. However, delineating the pathophysiology and finding a possible cure for the disease is still wanting. This is in part due to the lack of knowledge pertain...

journal_title：Frontiers in neuroscience

authors： Kumar A,Dhull DK,Mishra PS

更新日期：2015-06-09 00:00:00

abstract：:Cerebral ischemia is a complex pathology involving a cascade of cellular mechanisms, which deregulate proteostasis and lead to neuronal death. Proteostasis refers to the equilibrium between protein synthesis, folding, transport, and protein degradation. Within the brain proteostasis plays key roles in learning and mem...

journal_title：Frontiers in neuroscience

authors： Thiebaut AM,Hedou E,Marciniak SJ,Vivien D,Roussel BD

更新日期：2019-06-19 00:00:00

abstract：:This paper presents a unique approach for wavelet-based MRI brain image de-noising. Adaptive soft and hard threshold functions are first proposed to improve the results of standard soft and hard threshold functions for image de-noising in the wavelet domain. Then, we applied the newly emerged improved adaptive general...

journal_title：Frontiers in neuroscience

authors： Amiri Golilarz N,Gao H,Kumar R,Ali L,Fu Y,Li C

更新日期：2020-07-22 00:00:00

abstract：:Developing new standardized tools to characterize brain recording devices is critical to evaluate neural probes and for translation to clinical use. The signal-to-noise ratio (SNR) measurement is the gold standard for quantifying the performance of brain recording devices. Given the drawbacks with the SNR measure, our...

journal_title：Frontiers in neuroscience

authors： Suarez-Perez A,Gabriel G,Rebollo B,Illa X,Guimerà-Brunet A,Hernández-Ferrer J,Martínez MT,Villa R,Sanchez-Vives MV

更新日期：2018-11-29 00:00:00

abstract：:We investigated whether the C9orf72 repeat expansion is associated with specific clinical features, comorbidities, and prognosis in patients with amyotrophic lateral sclerosis (ALS). A cohort of 1417 ALS patients, diagnosed between January 1, 2009 and December 31, 2013 by 13 Italian ALS Referral Centers, was screened ...

journal_title：Frontiers in neuroscience

authors： Trojsi F,Siciliano M,Femiano C,Santangelo G,Lunetta C,Calvo A,Moglia C,Marinou K,Ticozzi N,Ferro C,Scialò C,Sorarù G,Conte A,Falzone YM,Tortelli R,Russo M,Sansone VA,Chiò A,Mora G,Silani V,Volanti P,Caponnetto C

更新日期：2019-05-17 00:00:00

abstract：:Social memory, including the ability to recognize faces and voices, is essential for social relationships. It has a large heritable component, but the knowledge about the contributing genes is sparse. The genetic variation underlying inter-individual differences in social memory was investigated in an exploratory samp...

journal_title：Frontiers in neuroscience

authors： Henningsson S,Zettergren A,Hovey D,Jonsson L,Svärd J,Cortes DS,Melke J,Ebner NC,Laukka P,Fischer H,Westberg L

更新日期：2015-10-21 00:00:00

abstract：:The auditory cortex integrates auditory information over time to obtain neural representations of sound events, the time scale of which critically affects perception. This work investigated the species differences in the time scale of integration by comparing humans and monkeys regarding how their scalp-recorded corti...

journal_title：Frontiers in neuroscience

authors： Itoh K,Nejime M,Konoike N,Nakamura K,Nakada T

更新日期：2019-06-24 00:00:00

abstract：Background:Cochlear implants (CIs) are auditory prostheses designed to support spoken communication in persons with severe to profound hearing loss. Many post-lingually deaf adult CI users achieve good speech recognition in quiet; unfortunately, CI technology conveys a degraded representation of pitch and timbre, essen...

journal_title：Frontiers in neuroscience

authors： Gfeller K,Mallalieu RM,Mansouri A,McCormick G,O'Connell RB,Spinowitz J,Gellinek Turner B

更新日期：2019-12-24 00:00:00

abstract：:Transcutaneous auricular vagus nerve stimulation (taVNS) has gained growing interest as a non-invasive and non-pharmacologic treatment option in various neurological and psychiatric disorders. Animal experiments and clinical trials confirm that taVNS at the auricular concha region has beneficial effects on depression....

journal_title：Frontiers in neuroscience

authors： Li S,Wang Y,Gao G,Guo X,Zhang Y,Zhang Z,Wang Y,Zhang J,Wang J,Li L,Yang Y,Rong P

更新日期：2020-07-15 00:00:00

abstract：:Lactate is a versatile metabolite with important roles in modulation of brain glucose utilization rate (CMRglc), diagnosis of brain-injured patients, redox- and receptor-mediated signaling, memory, and alteration of gene transcription. Neurons and astrocytes release and accumulate lactate using equilibrative monocarbo...

journal_title：Frontiers in neuroscience

authors： Hertz L,Gibbs ME,Dienel GA

更新日期：2014-09-09 00:00:00

abstract：:Motor performance varies substantially between individuals. This variance is rooted in individuals' innate motor abilities, and should thus have a neural signature underlying these differences in behavior. Could these individual differences be detectable with neural measurements acquired at rest? Here, we tested the h...

journal_title：Frontiers in neuroscience

authors： Herszage J,Dayan E,Sharon H,Censor N

更新日期：2020-02-05 00:00:00

abstract：:Although music has been utilized as a therapeutic tool for children with cognitive impairments, how it improves children's cognitive function remains poorly understood. As a first step toward understanding music's effectiveness and as a means of assessing cognitive function improvement, we focused on attention, which ...

journal_title：Frontiers in neuroscience

authors： Kasuya-Ueba Y,Zhao S,Toichi M

更新日期：2020-07-24 00:00:00

abstract：:We performed this study to investigate the possibility of a definitive pattern of Galectin-3 (Gal-3) expression in the cerebrospinal fluid (CSF) and serum of Alzheimer's disease (AD) and Amyotrophic Lateral Sclerosis (ALS) patients. In our study, we collected the CSF and serum samples of 31 AD patients, 19 ALS patient...

journal_title：Frontiers in neuroscience

authors： Ashraf GM,Baeesa SS

更新日期：2018-06-29 00:00:00

abstract：:Information processing in the cerebral cortex requires the activation of diverse neurons across layers and columns, which are established through the coordinated production of distinct neuronal subtypes and their placement along the three-dimensional axis. Over recent years, our knowledge of the regulatory mechanisms ...

journal_title：Frontiers in neuroscience

authors： Toma K,Hanashima C

更新日期：2015-08-11 00:00:00

abstract：:Decoding laminar information across deep brain structures and cortical regions is necessary in order to understand the neuronal ensembles that represent cognition and memory. Large animal models are essential for translational research due to their gyrencephalic neuroanatomy and significant white matter composition. A...

journal_title：Frontiers in neuroscience

authors： Ulyanova AV,Cottone C,Adam CD,Gagnon KG,Cullen DK,Holtzman T,Jamieson BG,Koch PF,Chen HI,Johnson VE,Wolf JA

更新日期：2019-04-26 00:00:00

abstract：:Persons diagnosed with disorders of consciousness (DOC) typically suffer from motor and cognitive disabilities. Recent research has shown that non-invasive brain-computer interface (BCI) technology could help assess these patients' cognitive functions and command following abilities. 20 DOC patients participated in th...

journal_title：Frontiers in neuroscience

authors： Murovec N,Heilinger A,Xu R,Ortner R,Spataro R,La Bella V,Miao Y,Jin J,Chatelle C,Laureys S,Allison BZ,Guger C

更新日期：2020-04-09 00:00:00

abstract：:Although flight is regarded as a key behavior of birds this review argues that the perceptual demands for its control are met within constraints set by the perceptual demands of two other key tasks: the control of bill (or feet) position, and the detection of food items/predators. Control of bill position, or of the f...

journal_title：Frontiers in neuroscience

authors： Martin GR

更新日期：2017-11-07 00:00:00

abstract：:Diabetes mellitus (DM) and Parkinson's disease (PD) have been and will continue to be two common chronic diseases globally that are difficult to diagnose during the prodromal phase. Current molecular genetics, cell biological, and epidemiological evidences have shown the correlation between PD and DM. PD shares the sa...

journal_title：Frontiers in neuroscience

authors： Kong Y,Zhou H,Feng H,Zhuang J,Wen T,Zhang C,Sun B,Wang J,Guan Y

更新日期：2020-07-14 00:00:00

abstract：:A large body of experimental and clinical evidence has strongly suggested that monoamines play an important role in regulating epileptogenesis, seizure susceptibility, convulsions, and comorbid psychiatric disorders commonly seen in people with epilepsy (PWE). However, neither the relative significance of individual m...

journal_title：Frontiers in neuroscience

authors： Svob Strac D,Pivac N,Smolders IJ,Fogel WA,De Deurwaerdere P,Di Giovanni G

更新日期：2016-11-10 00:00:00

abstract：:While the adult human brain has approximately 8.8 × 10(10) neurons, this number is dwarfed by its 1 × 10(15) synapses. From the point of view of neuromorphic engineering and neural simulation in general this makes the simulation of these synapses a particularly complex problem. SpiNNaker is a digital, neuromorphic arc...

journal_title：Frontiers in neuroscience

authors： Knight JC,Furber SB

更新日期：2016-09-14 00:00:00

abstract：:Interaural time differences (ITD) and interaural level differences (ILD) both signal horizontal sound source location. To achieve a unified percept of our acoustic environment, these two cues require integration. In the present study, we tested this integration of ITD and ILD with electroencephalography (EEG) by measu...

journal_title：Frontiers in neuroscience

authors： Altmann CF,Ueda R,Furukawa S,Kashino M,Mima T,Fukuyama H

更新日期：2017-07-06 00:00:00

abstract：:We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer's Disease Neuroimaging Initiative (ADNI). Sparse gro...

journal_title：Frontiers in neuroscience

authors： Kohannim O,Hibar DP,Stein JL,Jahanshad N,Hua X,Rajagopalan P,Toga AW,Jack CR Jr,Weiner MW,de Zubicaray GI,McMahon KL,Hansell NK,Martin NG,Wright MJ,Thompson PM,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2012-08-06 00:00:00

abstract：:Various studies performed in cultured cells and in in vivo models of neuronal damage showed that cannabinoids exert a neuroprotective effect. The increase in cannabinoids and cannabinoid like substances after stroke has been postulated to limit the content of neuronal injury. As well-accepted, inflammation, and neuron...

journal_title：Frontiers in neuroscience

authors： Hohmann U,Pelzer M,Kleine J,Hohmann T,Ghadban C,Dehghani F

更新日期：2019-11-07 00:00:00

abstract：:Adult neurogenesis is a tightly regulated process continuously taking place in the central nervous system of most mammalian species. In neuroscience research, transgenic animals bearing the tamoxifen-inducible CreERT2-Lox system are widely used. In this study, we made use of a Nestin-CreERT2/R26R-YFP transgenic mouse ...

journal_title：Frontiers in neuroscience

authors： Rotheneichner P,Romanelli P,Bieler L,Pagitsch S,Zaunmair P,Kreutzer C,König R,Marschallinger J,Aigner L,Couillard-Després S

更新日期：2017-02-01 00:00:00

abstract：Objectives:Many post-traumatic patients with minimally conscious state are complicated by psychomotor inhibition state (PIS), which impedes further rehabilitation. The treatment of PIS is not satisfactory. This pilot study aimed to investigate effects of anodal transcranial direct current stimulation (A-tDCS) on PIS in...

journal_title：Frontiers in neuroscience

authors： Zhang X,Liu B,Li N,Li Y,Hou J,Duan G,Wu D

更新日期：2020-05-20 00:00:00

abstract：:Sensory loss involves irreversible behavioral and neural changes. Paradigms of short-term limb immobilization mimic deprivation of proprioceptive inputs and motor commands, which occur after the loss of limb use. While several studies have shown that short-term immobilization induced motor control impairments, the ori...

journal_title：Frontiers in neuroscience

authors： Scotto CR,Meugnot A,Casiez G,Toussaint L

更新日期：2020-07-01 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00