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Anthropogenic Carbon Nanotubes Found in the Airways of Parisian Children.

Abstract：

:Compelling evidence shows that fine particulate matters (PMs) from air pollution penetrate lower airways and are associated with adverse health effects even within concentrations below those recommended by the WHO. A paper reported a dose-dependent link between carbon content in alveolar macrophages (assessed only by optical microscopy) and the decline in lung function. However, to the best of our knowledge, PM had never been accurately characterized inside human lung cells and the most responsible components of the particulate mix are still unknown. On another hand carbon nanotubes (CNTs) from natural and anthropogenic sources might be an important component of PM in both indoor and outdoor air. We used high-resolution transmission electron microscopy and energy dispersive X-ray spectroscopy to characterize PM present in broncho-alveolar lavage-fluids (n = 64) and inside lung cells (n = 5 patients) of asthmatic children. We show that inhaled PM mostly consist of CNTs. These CNTs are present in all examined samples and they are similar to those we found in dusts and vehicle exhausts collected in Paris, as well as to those previously characterized in ambient air in the USA, in spider webs in India, and in ice core. These results strongly suggest that humans are routinely exposed to CNTs.

journal_name

EBioMedicine

journal_title

EBioMedicine

authors

Kolosnjaj-Tabi J,Just J,Hartman KB,Laoudi Y,Boudjemaa S,Alloyeau D,Szwarc H,Wilson LJ,Moussa F

doi

10.1016/j.ebiom.2015.10.012

subject

Has Abstract

pub_date

2015-10-09 00:00:00

pages

1697-704

issue

11

issn

2352-3964

pii

S2352-3964(15)30175-4

journal_volume

2

pub_type

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