Hepatitis E Virus Infection Among Solid Organ Transplant Recipients at a North American Transplant Center.

abstract：BACKGROUND:Intra-abdominal infections (IAI) constitute a common reason for hospitalization. However, there is lack of standardization in empiric management of (1) anaerobes, (2) enterococci, (3) fungi, and (4) multidrug-resistant organisms (MDRO). The recommendation is to institute empiric coverage for some of these or...

journal_title：Open forum infectious diseases

authors： Marcus G,Levy S,Salhab G,Mengesha B,Tzuman O,Shur S,Burke E,Mayeda RC,Cochavi L,Perluk I,Zaidenstein R,Lazarovitch T,Dadon M,Marchaim D

更新日期：2016-12-20 00:00:00

abstract：Background:Patients heterozygous for mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more susceptible to respiratory infections than the general population. Methods :We conducted a retrospective case-control study using health insurance claims. We identified patients as either h...

journal_title：Open forum infectious diseases

authors： Polgreen PM,Brown GD,Hornick DB,Ahmad F,London B,Stoltz DA,Comellas AP

更新日期：2018-11-01 00:00:00

abstract：Background:Antibiotic-resistant bacterial infections are a major threat to public health, yet improper use of antibiotics remains high. Infectious Diseases (ID) fellows play a major role in antibiotic stewardship efforts, but there is little research on how they view stewardship activities. We performed a qualitative s...

journal_title：Open forum infectious diseases

authors： Morgan JR,Barlam TF,Drainoni ML

更新日期：2018-05-03 00:00:00

abstract：BACKGROUND:The incidence of recurrent herpes zoster (HZ) and the relationship between initial and recurrent HZ are not clear. METHODS:The Miyazaki Dermatologist Society has surveyed ~5000 patients with HZ annually since 1997. A questionnaire regarding HZ and its recurrence was completed by the dermatologists. RESULTS...

journal_title：Open forum infectious diseases

authors： Shiraki K,Toyama N,Daikoku T,Yajima M,Miyazaki Dermatologist Society.

更新日期：2017-01-28 00:00:00

abstract：BACKGROUND:Monitoring of immune function, measured by CD4 cell count, is an essential service for people with Human Immunodeficiency Virus (HIV). Prescription of antiretroviral (ARV) medications is contingent on CD4 cell count; patients without regular CD4 monitoring are unlikely to receive ARVs when indicated. This st...

journal_title：Open forum infectious diseases

authors： Davis AC,Watson G,Pourat N,Kominski GF,Roby DH

更新日期：2014-06-05 00:00:00

abstract：BACKGROUND:Lack of human immunodeficiency virus (HIV) infection awareness may be a driver of racial disparities in HIV infection among men who have sex with men (MSM). Lack of awareness is typically measured by comparing HIV test result to self-reported HIV status. This measure may be subject to reporting bias and alte...

journal_title：Open forum infectious diseases

authors： Sanchez TH,Kelley CF,Rosenberg E,Luisi N,O'Hara B,Lambert R,Coleman R,Frew P,Salazar LF,Tao S,Clarke W,Del Rio C,Sullivan PS

更新日期：2014-09-13 00:00:00

abstract：:Background.  The causes of varicella-zoster virus reactivation and herpes zoster (HZ) are largely unknown. We assessed potential risk factors for HZ, the data for which cannot be obtained from the medical sector. Methods.  We conducted a matched case-control study. We established active surveillance in Olmsted County,...

journal_title：Open forum infectious diseases

authors： Marin M,Harpaz R,Zhang J,Wollan PC,Bialek SR,Yawn BP

更新日期：2016-06-11 00:00:00

abstract：Background:Health departments utilize HIV surveillance data to identify people with HIV (PWH) who need re-linkage to HIV care as part of an approach known as Data to Care (D2C.) The most accurate, effective, and efficient method of identifying PWH for re-linkage is unknown. Methods:We evaluated referral and care conti...

journal_title：Open forum infectious diseases

authors： Sachdev DD,Mara E,Hughes AJ,Antunez E,Kohn R,Cohen S,Scheer S

更新日期：2020-08-21 00:00:00

abstract：Background:From an isolated epidemic, coronavirus disease 2019 has now emerged as a global pandemic. The availability of genomes in the public domain after the epidemic provides a unique opportunity to understand the evolution and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus across the g...

journal_title：Open forum infectious diseases

authors： Banu S,Jolly B,Mukherjee P,Singh P,Khan S,Zaveri L,Shambhavi S,Gaur N,Reddy S,Kaveri K,Srinivasan S,Gopal DR,Siva AB,Thangaraj K,Tallapaka KB,Mishra RK,Scaria V,Sowpati DT

更新日期：2020-09-18 00:00:00

abstract：:In this study, we report the case of a patient infected with human immunodeficiency virus (HIV)-1 who developed ataxia and neurocognitive impairment due to viral escape within the central nervous system (CNS) with a multidrug-resistant HIV-1 despite long-term viral suppression in plasma. Antiretroviral therapy optimiz...

journal_title：Open forum infectious diseases

authors： Béguelin C,Vázquez M,Bertschi M,Yerly S,de Jong D,Gutbrod K,Rauch A,Cusini A

更新日期：2015-12-28 00:00:00

abstract：:A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii-specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of removed cardiac va...

journal_title：Open forum infectious diseases

authors： Melenotte C,Loukil A,Rico A,Lepidi H,Raoult D

更新日期：2019-10-04 00:00:00

abstract：:Methods.  In a cross-sectional substudy of the Multicenter AIDS Cohort Study, noncontrast cardiac computed tomography (CT) scanning for coronary artery calcium (CAC) scoring was performed on all men, and, for men with normal renal function, coronary CT angiography (CTA) was performed. Associations between fat depots (...

journal_title：Open forum infectious diseases

authors： Palella FJ Jr,McKibben R,Post WS,Li X,Budoff M,Kingsley L,Witt MD,Jacobson LP,Brown TT

更新日期：2016-06-16 00:00:00

abstract：:Fast microbiological diagnostics (MDx) are needed to ensure early targeted antimicrobial treatment in sepsis. This systematic review focuses on the impact on antimicrobial management and patient outcomes of MDx for pathogen and resistance gene identification compared with blood cultures. PubMed was searched for clinic...

journal_title：Open forum infectious diseases

authors： D'Onofrio V,Salimans L,Bedenić B,Cartuyvels R,Barišić I,Gyssens IC

更新日期：2020-08-13 00:00:00

abstract：Background:Antibiotic stewardship programs (ASPs) are required at every hospital regardless of size. We conducted a qualitative study across different hospital settings to examine perspectives of physician and pharmacist stewards about the dynamics within their team and contextual factors that facilitate the success of...

journal_title：Open forum infectious diseases

authors： Barlam TF,Childs E,Zieminski SA,Meshesha TM,Jones KE,Butler JM,Damschroder LJ,Goetz MB,Madaras-Kelly K,Reardon CM,Samore MH,Shen J,Stenehjem E,Zhang Y,Drainoni ML

更新日期：2020-06-15 00:00:00

abstract：Background:Concomitant dosing of ledipasvir (LDV) and tenofovir disoproxil fumarate (TDF) results in an increased tenofovir (TFV) area under the curve (AUC). The aim of this study was to examine whether there was a correlation between the renal biomarkers retinol binding protein-4 (RBP-4) and β2 microglobulin (β2M) and...

journal_title：Open forum infectious diseases

authors： Chan A,Park L,Collins LF,Cooper C,Saag M,Dieterich D,Sulkowski M,Naggie S

更新日期：2019-01-24 00:00:00

abstract：Background:Retention in care (RIC) and viral suppression (VS) are associated with reduced HIV transmission and mortality. Studies addressing postpartum engagement in HIV care have been limited by small sample size, short follow-up, and a lack of data from the Southeast United States. Methods:HIV-positive adult women w...

journal_title：Open forum infectious diseases

authors： Oliver C,Rebeiro PF,Hopkins MJ,Byram B,Carpenter L,Clouse K,Castilho JL,Rogers W,Turner M,Bebawy SS,Pettit AC

更新日期：2019-01-19 00:00:00

abstract：Background:There are few longitudinal data on the risk factors and mediators of racial disparities in sepsis among community- dwelling US adults. Methods:This is a longitudinal study of adult participants in the 1999-2005 National Health Interview Survey with data linked to the 1999-2011 National Death Index. We utili...

journal_title：Open forum infectious diseases

authors： Kempker JA,Kramer MR,Waller LA,Martin GS

更新日期：2018-11-15 00:00:00

abstract：: Background.  The mechanism of virologic failure (VF) of lopinavir/ritonavir (LPV/r) monotherapy is not well understood. We assessed sequence changes in human immunodeficiency virus-1 reverse-transcriptase (RT) and protease (PR) regions. Methods. ...

journal_title：Open forum infectious diseases

authors： Vardhanabhuti S,Katzenstein D,Bartlett J,Kumarasamy N,Wallis CL

更新日期：2016-08-24 00:00:00

abstract：:We report a rare case of acute human immunodeficiency virus (HIV) syndrome in a patient with chronic HIV infection with acute illness indistinguishable from acute retroviral syndrome. The patient presented with an acute febrile mononucleosis-like illness after increasing nonadherence to antiretroviral therapy. A marke...

journal_title：Open forum infectious diseases

authors： Choi SK,Graber CJ

更新日期：2014-12-23 00:00:00

abstract：:Invasive aspergillosis (IA) is the most serious mold infection encountered in patients with iatrogenic immunosuppression. IA is also a major cause of mortality and morbidity in individuals with primary immunodeficiency (PID). Although Aspergillus fumigatus is the most common etiologic agent of IA reported in PID patie...

journal_title：Open forum infectious diseases

authors： Seyedmousavi S,Lionakis MS,Parta M,Peterson SW,Kwon-Chung KJ

更新日期：2018-09-26 00:00:00

abstract：:During 12 recent months of periodic influenza virus surveillance at 9 live poultry markets in Wuxi City China, we identified multiple highly pathogenic H5N6, H5N8, H5N2, and H5N1 avian influenza viruses. The variety of potentially pandemic viruses in this low-risk area is disconcerting and portends an increased pandem...

journal_title：Open forum infectious diseases

authors： Ma MJ,Chen SH,Wang GL,Zhao T,Qian YH,Wu MN,Liu Y,Gray GC,Lu B,Cao WC

更新日期：2016-03-09 00:00:00

abstract：:Background.  First- and second-generation smallpox vaccines are contraindicated in individuals infected with human immunodeficiency virus (HIV). A new smallpox vaccine is needed to protect this population in the context of biodefense preparedness. The focus of this study was to compare the safety and immunogenicity of...

journal_title：Open forum infectious diseases

authors： Overton ET,Stapleton J,Frank I,Hassler S,Goepfert PA,Barker D,Wagner E,von Krempelhuber A,Virgin G,Meyer TP,Müller J,Bädeker N,Grünert R,Young P,Rösch S,Maclennan J,Arndtz-Wiedemann N,Chaplin P

更新日期：2015-05-05 00:00:00

abstract：Background:Recent studies have favored the use of cefazolin over nafcillin for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. The clinical influence of the cefazolin inoculum effect (CzIE) in the effectiveness of cephalosporins for severe MSSA infections has not been evaluated. Metho...

journal_title：Open forum infectious diseases

authors： Miller WR,Seas C,Carvajal LP,Diaz L,Echeverri AM,Ferro C,Rios R,Porras P,Luna C,Gotuzzo E,Munita JM,Nannini E,Carcamo C,Reyes J,Arias CA

更新日期：2018-05-23 00:00:00

abstract：Background:There is growing interest in the use of rapid blood culture identification (BCID) in antimicrobial stewardship programs (ASPs). Although many studies have looked at its clinical and economic utility, its comparative utility in gram-positive and gram-negative blood stream infections (BSIs) has not been as wel...

journal_title：Open forum infectious diseases

authors： Tseng AS,Kasule SN,Rice F,Mi L,Chan L,Seville MT,Grys TE

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:Endothelial activation and dysfunction play a central role in the pathogenesis of sepsis and viral hemorrhagic fevers. Hantaviral disease is a viral hemorrhagic fever and is characterized by capillary dysfunction, although the underlying mechanisms for hantaviral disease are not fully elucidated. METHODS:Th...

journal_title：Open forum infectious diseases

authors： Connolly-Andersen AM,Thunberg T,Ahlm C

更新日期：2014-05-29 00:00:00

abstract：Background:Internal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents' ability to diagnose tuberculosis is important. Methods:Internal medicine resident knowledg...

journal_title：Open forum infectious diseases

authors： Chida N,Brown C,Mathad J,Carpenter K,Nelson G,Schechter MC,Giles N,Rebolledo PA,Ray S,Fabre V,Cantillo DS,Longworth S,Amorosa V,Petrauskis C,Boulanger C,Cain N,Gupta A,McKenzie-White J,Bollinger R,Melia MT

更新日期：2018-06-27 00:00:00

abstract：Background:Cryptococcal meningitis is a major cause of death among people with human immunodeficiency virus (PWH). Cryptococcal antigen (CrAg) testing of asymptomatic patients is an important public health measure to reduce mortality in high-incidence areas. However, limited data exist on CrAg prevalence in Central Ame...

journal_title：Open forum infectious diseases

authors： Zuniga-Moya JC,Romero-Reyes LE,Saavedra EB,Montoya S,Varela D,Borjas M,Cerna A,Bejarano S,Martinez P,Lujan K,Erazo K,Lainez I,Pineda L,Yanes D,O'Halloran JA,Spec A

更新日期：2020-11-13 00:00:00

abstract：Background:Patients with suspected tuberculosis are often overtreated with antituberculosis drugs. We evaluated the diagnostic value of the focused assessment with sonography for HIV-associated tuberculosis (FASH) in rural Tanzania. Methods:In a prospective cohort study, the frequency of FASH signs was compared betwee...

journal_title：Open forum infectious diseases

authors： Ndege R,Weisser M,Elzi L,Diggelmann F,Bani F,Gingo W,Sikalengo G,Mapesi H,Mchomvu E,Kamwela L,Mnzava D,Battegay M,Reither K,Paris DH,Rohacek M

更新日期：2019-04-25 00:00:00

abstract：:Respiratory syncytial virus (RSV) is an increasingly recognized cause of acute respiratory infection (ARI) in adults. We compared the crude in-hospital mortality of patients with RSV infection alone with that of patients with RSV-bacterial coinfection. Overall, 12 144 hospitalized patients with ARI were screened for R...

journal_title：Open forum infectious diseases

authors： Godefroy R,Giraud-Gatineau A,Jimeno MT,Edouard S,Meddeb L,Zandotti C,Chaudet H,Colson P,Raoult D,Cassir N

更新日期：2020-11-12 00:00:00

abstract：:We report a family who acquired acute toxoplasmosis after a trip to Central America. One member developed severe clinical manifestations including bilateral chorioretinitis, hepatitis, and myocarditis requiring therapy. Symptomatic acute toxoplasmosis is unusual and possesses a diagnostic challenge. We discuss the cli...

journal_title：Open forum infectious diseases

authors： Henao-Martínez AF,Franco-Paredes C,Palestine AG,Montoya JG

更新日期：2018-03-09 00:00:00