Interferon Lambda 4 Genotype Is Associated With Jaundice and Elevated Aminotransferase Levels During Acute Hepatitis C Virus Infection: Findings From the InC3 Collaborative.

abstract：:Background.  The efficacy of live, attenuated live attenuated influenza vaccine(LAIV) and inactivated influenza vaccine(IIV) is poorly explained by either single or composite immune responses to vaccination. Protective biomarkers were therefore studied in response to LAIV or IIV followed by LAIV challenge in children....

journal_title：Open forum infectious diseases

authors： Wright PF,Hoen AG,Ilyushina NA,Brown EP,Ackerman ME,Wieland-Alter W,Connor RI,Jegaskanda S,Rosenberg-Hasson Y,Haynes BC,Luke CJ,Subbarao K,Treanor JJ

更新日期：2016-05-23 00:00:00

abstract：Background:The United States is experiencing mumps outbreaks in settings with high 2-dose measles-mumps-rubella (MMR) vaccine coverage, mainly universities. The economic impact of mumps outbreaks on public health systems is largely unknown. During a 2015-2016 mumps outbreak at the University of Iowa, we estimated the c...

journal_title：Open forum infectious diseases

authors： Marin M,Kitzmann TL,James L,Quinlisk P,Aldous WK,Zhang J,Cardemil CV,Galeazzi C,Patel M,Ortega-Sanchez IR

更新日期：2018-10-04 00:00:00

abstract：Background:To determine the effectiveness of implementing a locally developed clinical practice guideline (CPG) for antibiotic treatment in adults with community-acquired cellulitis at Siriraj Hospital in Bangkok, Thailand. Methods:The CPG for antibiotic treatment of community-acquired cellulitis was developed based o...

journal_title：Open forum infectious diseases

authors： Sirijatuphat R,Nookeu P,Thamlikitkul V

更新日期：2020-09-07 00:00:00

abstract：:Despite the widespread outbreak, few cases of Zika virus associated with cardiac manifestations have been described. We present a case of pericarditis in the setting of an acute, symptomatic Zika virus infection in a traveler returning from St. Thomas. Clinicians should be alert for this potential complication of Zika...

journal_title：Open forum infectious diseases

authors： Waggoner JJ,Rouphael N,Xu Y,Natrajan M,Lai L,Patel SM,Levit RD,Edupuganti S,Mulligan MJ

更新日期：2017-05-18 00:00:00

abstract：Background:There are few longitudinal data on the risk factors and mediators of racial disparities in sepsis among community- dwelling US adults. Methods:This is a longitudinal study of adult participants in the 1999-2005 National Health Interview Survey with data linked to the 1999-2011 National Death Index. We utili...

journal_title：Open forum infectious diseases

authors： Kempker JA,Kramer MR,Waller LA,Martin GS

更新日期：2018-11-15 00:00:00

abstract：Background:New approaches are needed to provide care to persons with HIV who do not engage in conventionally organized HIV clinics. The Max Clinic in Seattle, Washington, is a walk-in, incentivized HIV care model located in a public health STD clinic that provides care in collaboration with a comprehensive HIV primary ...

journal_title：Open forum infectious diseases

authors： Dombrowski JC,Galagan SR,Ramchandani M,Dhanireddy S,Harrington RD,Moore A,Hara K,Eastment M,Golden MR

更新日期：2019-06-26 00:00:00

abstract：:Naegleria fowleri is a thermophilic free-living amoeba that is found in warm, fresh water and causes primary amebic meningoencephalitis (PAM). The following report demonstrates the rapid and destructive clinical features of PAM in an 8-year-old male who presented with severe headaches approximately 12 days after swimm...

journal_title：Open forum infectious diseases

authors： Vareechon C,Tarro T,Polanco C,Anand V,Pannaraj PS,Dien Bard J

更新日期：2019-07-29 00:00:00

abstract：Background:Post-kala-azar dermal leishmaniasis (PKDL) is a sequel to visceral leishmaniasis (VL), which is found in VL-endemic countries including Bangladesh. Because of these enigmatic cases, the success of the National Kala-azar Elimination Program is under threat. To date, diagnostic methods for PKDL cases in endemi...

journal_title：Open forum infectious diseases

authors： Ghosh P,Hasnain MG,Hossain F,Khan MAA,Chowdhury R,Faisal K,Mural MA,Baker J,Nath R,Ghosh D,Maruf S,Shomik MS,Haque R,Matlashewski G,Hamano S,Duthie MS,Mondal D

更新日期：2018-09-15 00:00:00

abstract：Background:Maintaining retention in preexposure prophylaxis (PrEP) care among diverse patient populations will be needed to support PrEP's efficacy. We characterized patterns of PrEP care retention in a US municipal primary care health network and examined whether missed visits, a metric of care retention that is easy ...

journal_title：Open forum infectious diseases

authors： Spinelli MA,Scott HM,Vittinghoff E,Liu AY,Gonzalez R,Morehead-Gee A,Gandhi M,Buchbinder SP

更新日期：2019-02-26 00:00:00

abstract：:We treated three pediatric cardiac transplant patients with chronic parvovirus viremia with high-dose intravenous immunoglobulin (HD-IVIG). One patient with severe T-cell lymphopenia suffered recurrent viremia and aseptic meningitis, which resolved remarkably when he was switched to high-dose hyaluronidase-facilitated...

journal_title：Open forum infectious diseases

authors： Cruz RJ,Dasso JF,Duff C,Krasnopero D,Long Z,Ellison M,Nieves D,Sriaroon P,Asante-Korang A,Walter JE

更新日期：2020-03-12 00:00:00

abstract：:Fusarium species are ubiquitous fungi causing a wide array of infections, including invasive disease in the immunosuppressed. We present a fusarium bone infection in a child with Pearson syndrome and review the literature. Ten cases of fusarium osteomyelitis were reported in the past 40 years, and we review the treatm...

journal_title：Open forum infectious diseases

authors： Hiebert RM,Welliver RC,Yu Z

更新日期：2016-10-07 00:00:00

abstract：:Immune suppression is a recognized risk factor for necrotizing fasciitis. In patients with hematological malignancies, a profoundly immunocompromised group, the predominant causative organisms are Gram negative. Clinical presentation and outcomes in these patients are similar to the immunocompetent. The Laboratory Ris...

journal_title：Open forum infectious diseases

authors： Foo RM,Tung ML,Poon LM,Chan D,Smitasin N,Koh LP,Chng WJ,Chai LY

更新日期：2015-06-12 00:00:00

abstract：Background:Coagulation activity among persons with HIV is associated with end-organ disease risk, but the pathogenesis is not well characterized. We tested a hypothesis that hypercoagulation contributes to disease risk, in part, via upregulation of inflammation. Methods:Treatment effects of edoxaban (30 mg), a direct ...

journal_title：Open forum infectious diseases

authors： Baker JV,Wolfson J,Peterson T,Mooberry M,Gissel M,Mystakelis H,Henderson MW,Garcia-Myers K,Rhame FS,Schacker TW,Brummel-Ziedins KE,Sereti I,Key NS,Tracy RP

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Clostridium difficile infection (CDI) is no longer restricted to hospital settings, and population-based incidence measures are needed. Understanding the determinants of CDI incidence will allow for more meaningful comparisons of rates and accurate national estimates. METHODS:Data from active population- an...

journal_title：Open forum infectious diseases

authors： Lessa FC,Mu Y,Winston LG,Dumyati GK,Farley MM,Beldavs ZG,Kast K,Holzbauer SM,Meek JI,Cohen J,McDonald LC,Fridkin SK

更新日期：2014-07-28 00:00:00

abstract：:A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii-specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of removed cardiac va...

journal_title：Open forum infectious diseases

authors： Melenotte C,Loukil A,Rico A,Lepidi H,Raoult D

更新日期：2019-10-04 00:00:00

abstract：Background:Hepatitis C remains a major cause of liver disease globally and is responsible for approximately 500 000 deaths annually. Newer direct-acting antivirals achieve cure rates at or above 90% with excellent tolerability for most patients. The literature focusing on identification of predictors of efficacy and sa...

journal_title：Open forum infectious diseases

authors： Jansen JW,Linneman TW,Powderly GM,Moenster RP,Nayak L

更新日期：2019-02-19 00:00:00

abstract：Background:Hydatid disease is a severe health problem in endemic areas. In recent years, the incidence of this disease in China has been increasing. As the imaging characteristics of pancreatic echinococcosis (PE) are similar to those of cystic diseases, such as cysts, tuberculosis, and tumors, PE is often misdiagnosed...

journal_title：Open forum infectious diseases

authors： Gou L,Gao F,Tiheiran M,Guo H

更新日期：2020-04-03 00:00:00

abstract：:Background.  The causes of varicella-zoster virus reactivation and herpes zoster (HZ) are largely unknown. We assessed potential risk factors for HZ, the data for which cannot be obtained from the medical sector. Methods.  We conducted a matched case-control study. We established active surveillance in Olmsted County,...

journal_title：Open forum infectious diseases

authors： Marin M,Harpaz R,Zhang J,Wollan PC,Bialek SR,Yawn BP

更新日期：2016-06-11 00:00:00

abstract：BACKGROUND:Among the 1.2 M persons living with HIV in the United States, 25% are co- infected with HCV. The availability of effective direct antiviral agents (DAAs) makes the goal of HCV elimination feasible, but implementation requires improvements to the HCV treatment cascade, especially linkage to and initiation of ...

journal_title：Open forum infectious diseases

authors： Rizk C,Miceli J,Shiferaw B,Malinis M,Barakat L,Ogbuagu O,Villanueva M

更新日期：2019-08-14 00:00:00

abstract：Background:Penicillin allergy frequently impacts antibiotic choice. As beta-lactams are superior to vancomycin in treating methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, we examined the effect of reported penicillin allergy on clinical outcomes in patients with MSSA bacteremia. Methods:In this retros...

journal_title：Open forum infectious diseases

authors： Turner NA,Moehring R,Sarubbi C,Wrenn RH,Drew RH,Cunningham CK,Fowler VG,Anderson DJ

更新日期：2018-02-19 00:00:00

abstract：:International guidelines recommend using local susceptibility data to direct empiric therapy for acute uncomplicated cystitis. We evaluated outpatient urinary isolate susceptibility trends in New York State. Nitrofurantoin had the lowest resistance prevalence whereas trimethoprim-sulfamethoxazole and fluoroquinolones ...

journal_title：Open forum infectious diseases

authors： Rank EL,Lodise T,Avery L,Bankert E,Dobson E,Dumyati G,Hassett S,Keller M,Pearsall M,Lubowski T,Carreno JJ

更新日期：2018-11-16 00:00:00

abstract：:Background.  During pregnancy, the placenta is inaccessible for diagnosis of placental malaria (PM), but soluble tumor necrosis factor-α receptors (sTNFR) are elevated in the plasma of women with PM. Methods.  In this study, sTNFR-1 and sTNFR-2 were quantified in urine of pregnant and nonpregnant Cameroonian women who...

journal_title：Open forum infectious diseases

authors： Tassi Yunga S,Thévenon AD,Leke RG,Taylor DW

更新日期：2016-04-26 00:00:00

abstract：:Background.  Practicing antimicrobial stewardship in the setting of widespread antimicrobial resistance among gram-negative bacilli, particularly in urban areas, is challenging. Methods.  We conducted a retrospective cross-sectional study at a tertiary care hospital with an established antimicrobial stewardship progra...

journal_title：Open forum infectious diseases

authors： Vora NM,Kubin CJ,Furuya EY

更新日期：2015-02-19 00:00:00

abstract：:We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered i...

journal_title：Open forum infectious diseases

authors： Springer SA,Masciotra S,Johnson JA,Campbell S

更新日期：2020-10-10 00:00:00

abstract：:Ebola virus (EBOV) is a highly pathogenic filovirus that causes outbreaks of a severe hemorrhagic fever known as EBOV disease (EVD). Ebola virus disease is characterized in part by a dysregulated immune response and massive production of both pro- and anti-inflammatory cytokines. To better understand the immune respon...

journal_title：Open forum infectious diseases

authors： Banadyga L,Siragam V,Zhu W,He S,Cheng K,Qiu X

更新日期：2019-02-06 00:00:00

abstract：Background:Little information is available on the relative tolerability of ceftaroline versus other cephalosporins in clinical practice. We sought to compare adverse drug reactions (ADRs) associated with ceftaroline with those associated with ceftriaxone in hospitalized patients. Materials and Methods:This was a retro...

journal_title：Open forum infectious diseases

authors： Jansen JW,Linneman TW,Tan X,Moenster RP

更新日期：2019-06-13 00:00:00

abstract：:During the current Zika virus (ZIKV) outbreak, acute symptomatic ZIKV infection in adults appears to be a mild-to-moderate, self-limited illness. We present a case of ZIKV rash illness that improved and then relapsed without repeat exposure to ZIKV. Clinicians should be alert for relapses in patients with ZIKV infecti...

journal_title：Open forum infectious diseases

authors： Edupuganti S,Natrajan MS,Rouphael N,Lai L,Xu Y,Feldhammer M,Hill C,Patel SM,Johnson SJ,Bower M,Gorchakov R,Berry R,Murray KO,Mulligan MJ

更新日期：2017-06-22 00:00:00

abstract：Background:Cytomegalovirus retinitis is a treatable cause of blindness in people with human immunodeficiency virus (HIV) typically with CD4 counts <50 cells/mm3. Diagnosis is with indirect fundoscopy, and treatment is with intravitreal ganciclovir injections or systemic therapy. However, diagnosis and treatment are not...

journal_title：Open forum infectious diseases

authors： Ocieczek P,Barnacle JR,Gumulira J,Phiri S,Heller T,Grabska-Liberek I

更新日期：2019-11-06 00:00:00

abstract：:Thrombocytopenia is a characteristic feature during the acute phase of dengue infection and has been found to associate with vascular leakage in severe dengue. Although dengue antigens have been observed in platelets, there is no strong evidence to suggest a direct infection of platelets by dengue virus as a contribut...

journal_title：Open forum infectious diseases

authors： Kar M,Singla M,Chandele A,Kabra SK,Lodha R,Medigeshi GR

更新日期：2017-03-23 00:00:00

abstract：Background:Cytomegalovirus (CMV) mononucleosis is a manifestation of primary CMV infection. This study aims to establish the link between long-term population CMV seroepidemiological trends and incidence of CMV mononucleosis requiring hospitalization. Furthermore, by analyzing serial laboratory data of patients hospita...

journal_title：Open forum infectious diseases

authors： Sridhar S,Chung TWH,Chan JFW,Cheng VCC,Lau SKP,Yuen KY,Woo PCY

更新日期：2018-10-20 00:00:00