Abstract:
:In this study, we report the case of a patient infected with human immunodeficiency virus (HIV)-1 who developed ataxia and neurocognitive impairment due to viral escape within the central nervous system (CNS) with a multidrug-resistant HIV-1 despite long-term viral suppression in plasma. Antiretroviral therapy optimization with drugs with high CNS penetration led to viral suppression in the CSF, regression of ataxia, and improvement of neurocognitive symptoms.
journal_name
Open Forum Infect Disjournal_title
Open forum infectious diseasesauthors
Béguelin C,Vázquez M,Bertschi M,Yerly S,de Jong D,Gutbrod K,Rauch A,Cusini Adoi
10.1093/ofid/ofv210subject
Has Abstractpub_date
2015-12-28 00:00:00pages
ofv210issue
1issn
2328-8957pii
ofv210journal_volume
3pub_type
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