Bereavement after sibling death: a population-based longitudinal case-control study.

Abstract:

:The objective of this study was to examine mental disorders and treatment use among bereaved siblings in the general population. Siblings (N=7243) of all deceased children in the population of Manitoba, Canada who died between 1984 and 2009 were matched 1:3 to control siblings (N=21,729) who did not have a sibling die in the study period. Generalized estimating equations were used to compare the two sibling groups in the two years before and after the index child's death on physician-diagnosed mental disorders and treatment utilization, with adjustment for confounding factors including pre-existing mental illness. Analyses were stratified by age of the bereaved (<13 vs. 13+). Results revealed that, in the two years after the death of the child, bereaved siblings had significantly higher rates of mental disorders than control siblings, even after adjusting for pre-existing mental illness. When comparing the effect of a child's death on younger versus older siblings, the rise in depression rates from pre-death to post-death was significantly higher for siblings aged under 13 (p<0.0001), increasing more than 7-fold (adjusted relative rate, ARR=7.25, 95% CI: 3.65-14.43). Bereaved siblings aged 13+ had substantial morbidity in the two years after the death: 25% were diagnosed with a mental disorder (vs. 17% of controls), and they had higher rates of almost all mental disorder outcomes compared to controls, including twice the rate of suicide attempts (ARR=2.01, 95% CI: 1.29-3.12). Siblings in the bereaved cohort had higher rates of alcohol and drug use disorders already before the death of their sibling. In conclusion, the death of a child is associated with considerable mental disorder burden among surviving siblings. Pre-existing health problems and social disadvantage do not fully account for the increase in mental disorder rates.

journal_name

World Psychiatry

authors

Bolton JM,Au W,Chateau D,Walld R,Leslie WD,Enns J,Martens PJ,Katz LY,Logsetty S,Sareen J

doi

10.1002/wps.20293

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

59-66

issue

1

eissn

1723-8617

issn

2051-5545

journal_volume

15

pub_type

杂志文章
  • Metabolic syndrome in people with schizophrenia: a review.

    abstract::Metabolic syndrome and other cardiovascular risk factors are highly prevalent in people with schizophrenia. Patients are at risk for premature mortality and overall have limited access to physical health care. In part these cardio-metabolic risk factors are attributable to unhealthy lifestyle, including poor diet and ...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2009.tb00199.x

    authors: DE Hert M,Schreurs V,Vancampfort D,VAN Winkel R

    更新日期:2009-02-01 00:00:00

  • Reform of mental health care in Serbia: ten steps plus one.

    abstract::Disastrous events in the country and the region caused a 13.5% increase in the prevalence of mental and behavioral disorders in Serbia in the last few years, thus making them the second largest public health problem. Due to prolonged adversities, the health system has deteriorated and is facing specific challenges. Ho...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Lecic Tosevski D,Pejovic Milovancevic M,Popovic Deusic S

    更新日期:2007-06-01 00:00:00

  • Mental health services in the Arab world.

    abstract::This paper summarizes the current situation of mental health services in the Arab world. Out of 20 countries for which information is available, six do not have a mental health legislation and two do not have a mental health policy. Three countries (Lebanon, Kuwait and Bahrain) had in 2007 more than 30 psychiatric bed...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1016/j.wpsyc.2012.01.008

    authors: Okasha A,Karam E,Okasha T

    更新日期:2012-02-01 00:00:00

  • The future of psychological therapies for psychosis.

    abstract::The need for psychological therapies for psychosis is increasingly recognised. In recent years, two psychological approaches, cognitive behavioural therapy (CBT) and family interventions (FI), have emerged from among a range of psychological approaches as effective therapies with the strongest evidence base. The theor...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Garety PA

    更新日期:2003-10-01 00:00:00

  • Randomized controlled trial of supported employment in England: 2 year follow-up of the Supported Work and Needs (SWAN) study.

    abstract::Studies from North America have concluded that supported employment using the Individual Placement and Support (IPS) model is effective in helping individuals with severe and persistent mental illness gain competitive employment. The aim of this study was to investigate the effectiveness and cost-effectiveness of IPS ...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2011.tb00035.x

    authors: Heslin M,Howard L,Leese M,McCrone P,Rice C,Jarrett M,Spokes T,Huxley P,Thornicroft G

    更新日期:2011-06-01 00:00:00

  • Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis.

    abstract::Metabolic syndrome (MetS) and its components are highly predictive of cardiovascular diseases. The primary aim of this systematic review and meta-analysis was to assess the prevalence of MetS and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20252

    authors: Vancampfort D,Stubbs B,Mitchell AJ,De Hert M,Wampers M,Ward PB,Rosenbaum S,Correll CU

    更新日期:2015-10-01 00:00:00

  • Problematic Internet use: an overview.

    abstract::There is wide agreement that the Internet can serve as a tool that enhances well-being. It is more difficult, however, to find consensus around the issue of problematic Internet use. That may be in part because scientific investigation has lagged far behind technological advances and media attention. The diagnostic sc...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2010.tb00278.x

    authors: Aboujaoude E

    更新日期:2010-06-01 00:00:00

  • Research for Change: the role of scientific journals publishing mental health research.

    abstract::There is an enormous gap between the burden of mental disorders and mental health resources in low- and middle-income countries. The Mental Health: Global Action Programme of the World Health Organization (WHO) envisions an active role for research in the multidimensional efforts required to change the current mental ...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Saxena S,Sharan P,Saraceno B

    更新日期:2004-06-01 00:00:00

  • Predictors of type 2 diabetes in a nationally representative sample of adults with psychosis.

    abstract::Antipsychotic drugs such as clozapine and olanzapine are associated with an increased risk for type 2 diabetes, but relatively little is known about the relationship between risk factors for type 2 diabetes established in the general population and type 2 diabetes in people with psychosis. We estimated the prevalence ...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20130

    authors: Foley DL,Mackinnon A,Morgan VA,Watts GF,McGrath JJ,Castle DJ,Waterreus A,Galletly CA

    更新日期:2014-06-01 00:00:00

  • Childhood adversities and psychosis: evidence, challenges, implications.

    abstract::There is a substantial body of research reporting evidence of associations between various forms of childhood adversity and psychosis, across the spectrum from experiences to disorder. This has been extended, more recently, to include studies of cumulative effects, of interactions with other factors, of specific effec...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20330

    authors: Morgan C,Gayer-Anderson C

    更新日期:2016-06-01 00:00:00

  • The unique challenges of managing depression in mid-life women.

    abstract::Throughout most of their lives, women are at a greater risk of becoming depressed than men. Some evidence suggests that this heightened risk is associated with increased sensitivity to the hormonal changes that occur across the female reproductive lifecycle. For some women, the peri-menopause and early post-menopausal...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2008.tb00180.x

    authors: Dennerstein L,Soares CN

    更新日期:2008-10-01 00:00:00

  • The clinical characterization of the adult patient with depression aimed at personalization of management.

    abstract::Depression is widely acknowledged to be a heterogeneous entity, and the need to further characterize the individual patient who has received this diagnosis in order to personalize the management plan has been repeatedly emphasized. However, the research evidence that should guide this personalization is at present fra...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20771

    authors: Maj M,Stein DJ,Parker G,Zimmerman M,Fava GA,De Hert M,Demyttenaere K,McIntyre RS,Widiger T,Wittchen HU

    更新日期:2020-10-01 00:00:00

  • Mental health policies on reporting child sexual abuse and physician-patient sexual relationships.

    abstract::The reporting of child sexual abuse (CSA) and physician-patient sexual relationships (PPSR) are currently the focus of professional, legal and media attention in several countries. This paper briefly reviews mental health policies on these issues and reports on a WPA survey of them. While the WPA Madrid Declaration pe...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2009.tb00210.x

    authors: Stewart DE,Venos E,Ashraf IJ

    更新日期:2009-02-01 00:00:00

  • Non-adherence to medication in patients with psychotic disorders: epidemiology, contributing factors and management strategies.

    abstract::Although non-adherence is common across all branches of medicine, psychotic disorders pose additional challenges that increase its risk. Despite the importance of non-adherence, clinicians generally spend too little time on assessing and addressing adherence attitudes and behaviors. Importantly, how adherence is measu...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20060

    authors: Kane JM,Kishimoto T,Correll CU

    更新日期:2013-10-01 00:00:00

  • Child murder by mothers: patterns and prevention.

    abstract::The tragedy of maternal filicide, or child murder by mothers, has occurred throughout history and throughout the world. This review of the research literature sought to identify common predictors in the general population as well as in correctional and psychiatric samples. Further research is needed to improve identif...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Hatters Friedman S,Resnick PJ

    更新日期:2007-10-01 00:00:00

  • Efficacy and safety of deep transcranial magnetic stimulation for major depression: a prospective multicenter randomized controlled trial.

    abstract::Major depressive disorder (MDD) is a prevalent and disabling condition, and many patients do not respond to available treatments. Deep transcranial magnetic stimulation (dTMS) is a new technology allowing non-surgical stimulation of relatively deep brain areas. This is the first double-blind randomized controlled mult...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20199

    authors: Levkovitz Y,Isserles M,Padberg F,Lisanby SH,Bystritsky A,Xia G,Tendler A,Daskalakis ZJ,Winston JL,Dannon P,Hafez HM,Reti IM,Morales OG,Schlaepfer TE,Hollander E,Berman JA,Husain MM,Sofer U,Stein A,Adler S,Deutsch

    更新日期:2015-02-01 00:00:00

  • Testing structural models of psychopathology at the genomic level.

    abstract::Genome-wide association studies (GWAS) have revealed hundreds of genetic loci associated with the vulnerability to major psychiatric disorders, and post-GWAS analyses have shown substantial genetic correlations among these disorders. This evidence supports the existence of a higher-order structure of psychopathology a...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20772

    authors: Waldman ID,Poore HE,Luningham JM,Yang J

    更新日期:2020-10-01 00:00:00

  • Quality of life in mental disorders: challenges for research and clinical practice.

    abstract::The term quality of life (Qol) has become a rallying cry for all those who strive to integrate patients' subjective experience of their life during illness into clinical care. With its intuitive appeal, Qol seems to be understood by everyone involved in managing health and disease. However, when examining the ever inc...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Katschnig H

    更新日期:2006-10-01 00:00:00

  • A meta-analysis of cardio-metabolic abnormalities in drug naïve, first-episode and multi-episode patients with schizophrenia versus general population controls.

    abstract::A meta-analysis was conducted to explore the risk for cardio-metabolic abnormalities in drug naïve, first-episode and multi-episode patients with schizophrenia and age- and gender- or cohort-matched general population controls. Our literature search generated 203 relevant studies, of which 136 were included. The final...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20069

    authors: Vancampfort D,Wampers M,Mitchell AJ,Correll CU,De Herdt A,Probst M,De Hert M

    更新日期:2013-10-01 00:00:00

  • Integrating mental health into primary health care: local initiatives from Uganda.

    abstract::Uganda has passed through political and bloody civil strife stretching over 40 years. Since 1987 the HIV/AIDS pandemic has compounded the problems of the country. The present paper describes some initiatives to develop mental health services in one district of the country. A bottom-up approach in the district resulted...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Ovuga E,Boardman J,Wasserman D

    更新日期:2007-02-01 00:00:00

  • Probing cortical dopamine function in schizophrenia: what can D1 receptors tell us?

    abstract::Schizophrenia is characterized by positive symptoms, negative symptoms and cognitive impairment. Positive symptoms may be related to excessive dopamine (DA) function, as suggested by the common antidopaminergic properties of antipsychotic medications, which are most effective at treating positive symptoms. Negative sy...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Abi-Dargham A

    更新日期:2003-10-01 00:00:00

  • Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.

    abstract::Poor insight in schizophrenia is prevalent across cultures and phases of illness. In this review, we examine the recent research on the relationship of insight with behavior, mood and perceived quality of life, on its complex roots, and on the effects of existing and emerging treatments. This research indicates that p...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20508

    authors: Lysaker PH,Pattison ML,Leonhardt BL,Phelps S,Vohs JL

    更新日期:2018-02-01 00:00:00

  • Hypomania: a transcultural perspective.

    abstract::This study examined the transcultural robustness of a screening instrument for hypomania, the Hypomania Checklist-32, first revised version (HCL-32 R1). It was carried out in 2606 patients from twelve countries in five geographic regions (Northern, Southern and Eastern Europe, South America and East Asia). In addition...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2010.tb00268.x

    authors: Angst J,Meyer TD,Adolfsson R,Skeppar P,Carta M,Benazzi F,Lu RB,Wu YH,Yang HC,Yuan CM,Morselli P,Brieger P,Katzmann J,Teixeira Leão IA,Del Porto JA,Hupfeld Moreno D,Moreno RA,Soares OT,Vieta E,Gamma A

    更新日期:2010-02-01 00:00:00

  • The promise of cognitive behavior therapy for treatment of severe mental disorders: a review of recent developments.

    abstract::Cognitive behavior therapy (CBT), as exemplified by the model of psychotherapy developed and refined over the past 40 years by A.T. Beck and colleagues, is one of the treatments of first choice for ambulatory depressive and anxiety disorders. Over the past several decades, there have been vigorous efforts to adapt CBT...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20149

    authors: Thase ME,Kingdon D,Turkington D

    更新日期:2014-10-01 00:00:00

  • Recent developments in the theory of dissociation.

    abstract::Although the construct of dissociation was introduced into psychiatry at the end of the 19th century by Pierre Janet, the term still lacks a coherent conceptualization, which is partially reflected by differences in the classification of dissociative and conversion disorders in ICD-10 and DSM-IV. Given the clinical si...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:

    authors: Spitzer C,Barnow S,Freyberger HJ,Grabe HJ

    更新日期:2006-06-01 00:00:00

  • How well can post-traumatic stress disorder be predicted from pre-trauma risk factors? An exploratory study in the WHO World Mental Health Surveys.

    abstract::Post-traumatic stress disorder (PTSD) should be one of the most preventable mental disorders, since many people exposed to traumatic experiences (TEs) could be targeted in first response settings in the immediate aftermath of exposure for preventive intervention. However, these interventions are costly and the proport...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20150

    authors: Kessler RC,Rose S,Koenen KC,Karam EG,Stang PE,Stein DJ,Heeringa SG,Hill ED,Liberzon I,McLaughlin KA,McLean SA,Pennell BE,Petukhova M,Rosellini AJ,Ruscio AM,Shahly V,Shalev AY,Silove D,Zaslavsky AM,Angermeyer MC,Br

    更新日期:2014-10-01 00:00:00

  • Estimating treatment coverage for people with substance use disorders: an analysis of data from the World Mental Health Surveys.

    abstract::Substance use is a major cause of disability globally. This has been recognized in the recent United Nations Sustainable Development Goals (SDGs), in which treatment coverage for substance use disorders is identified as one of the indicators. There have been no estimates of this treatment coverage cross-nationally, ma...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20457

    authors: Degenhardt L,Glantz M,Evans-Lacko S,Sadikova E,Sampson N,Thornicroft G,Aguilar-Gaxiola S,Al-Hamzawi A,Alonso J,Helena Andrade L,Bruffaerts R,Bunting B,Bromet EJ,Miguel Caldas de Almeida J,de Girolamo G,Florescu S,Gureje O

    更新日期:2017-10-01 00:00:00

  • The severity of psychiatric disorders.

    abstract::The issue of the severity of psychiatric disorders has great clinical importance. For example, severity influences decisions about level of care, and affects decisions to seek government assistance due to psychiatric disability. Controversy exists as to the efficacy of antidepressants across the spectrum of depression...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20569

    authors: Zimmerman M,Morgan TA,Stanton K

    更新日期:2018-10-01 00:00:00

  • Lessons learned in developing community mental health care in Latin American and Caribbean countries.

    abstract::This paper summarizes the findings for the Latin American and Caribbean countries of the WPA Task Force on Steps, Obstacles and Mistakes to Avoid in the Implementation of Community Mental Health Care. It presents an overview of the provision of mental health services in the region; describes key experiences in Argenti...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/j.2051-5545.2012.tb00130.x

    authors: Razzouk D,Gregório G,Antunes R,Mari JD

    更新日期:2012-10-01 00:00:00

  • Psychotherapies for depression in low- and middle-income countries: a meta-analysis.

    abstract::Most psychotherapies for depression have been developed in high-income Western countries of North America, Europe and Australia. A growing number of randomized trials have examined the effects of these treatments in non-Western countries. We conducted a meta-analysis of these studies to examine whether these psychothe...

    journal_title:World psychiatry : official journal of the World Psychiatric Association (WPA)

    pub_type: 杂志文章

    doi:10.1002/wps.20493

    authors: Cuijpers P,Karyotaki E,Reijnders M,Purgato M,Barbui C

    更新日期:2018-02-01 00:00:00