To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making.

Abstract:

:Decision-making is an ethologically adaptive construct that is impaired in multiple psychiatric disorders. Activity within the mesocorticolimbic dopamine system has been traditionally associated with decision-making. The endocannabinoid system through its actions on inhibitory and excitatory synapses modulates dopamine activity and decision-making. The aim of this brief review is to present a synopsis of available data obtained when the endocannabinoid system is manipulated and dopamine activity recorded. To this end, we review research using different behavioral paradigms to provide further insight into how this ubiquitous signaling system biases dopamine-related behaviors to regulate decision-making.

journal_name

Front Behav Neurosci

authors

Hernandez G,Cheer JF

doi

10.3389/fnbeh.2015.00336

subject

Has Abstract

pub_date

2015-12-17 00:00:00

pages

336

issn

1662-5153

journal_volume

9

pub_type

杂志文章,评审
  • Validating Rat Model of Empathy for Pain: Effects of Pain Expressions in Social Partners.

    abstract::Pain can be socially transferred between familiar rats due to empathic responses. To validate rat model of empathy for pain, effects of pain expressions in a cagemate demonstrator (CD) in pain on empathic pain responses in a naïve cagemate observer (CO) after 30 min priming dyadic social interactions (PDSI) were evalu...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2018.00242

    authors: Li CL,Yu Y,He T,Wang RR,Geng KW,Du R,Luo WJ,Wei N,Wang XL,Wang Y,Yang Y,Yu YQ,Chen J

    更新日期:2018-10-17 00:00:00

  • Differences in social interaction- vs. cocaine reward in mouse vs. rat.

    abstract::We previously developed rat experimental models based on the conditioned place preference (CPP) paradigm in which only four 15-min episodes of dyadic social interaction with a sex- and weight-matched male Sprague Dawley (SD) rat (1) reversed CPP from cocaine to social interaction despite continuing cocaine training, a...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2014.00363

    authors: Kummer KK,Hofhansel L,Barwitz CM,Schardl A,Prast JM,Salti A,El Rawas R,Zernig G

    更新日期:2014-10-17 00:00:00

  • Immune-Endocrine Links to Gregariousness in Wild House Mice.

    abstract::Social interactions are critically important for survival and impact overall-health, but also impose costs on animals, such as exposure to contagious agents. The immune system can play a critical role in modulating social behavior when animals are sick, as has been demonstrated within the context of "sickness behavior...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2020.00010

    authors: Lopes PC,Carlitz EHD,Kindel M,König B

    更新日期:2020-02-05 00:00:00

  • Behavioral and Immunohistochemical Study of the Effects of Subchronic and Chronic Exposure to Glyphosate in Mice.

    abstract::Many epidemiological studies have described an adolescent-related psychiatric illness and sensorimotor deficits after Glyphosate based herbicide (GBH) exposure. GBH exposure in animal models of various ages suggests that it may be neurotoxic and could impact brain development and subsequently, behavior in adulthood. H...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2017.00146

    authors: Ait Bali Y,Ba-Mhamed S,Bennis M

    更新日期:2017-08-08 00:00:00

  • Pupil Dynamics Reflect Behavioral Choice and Learning in a Go/NoGo Tactile Decision-Making Task in Mice.

    abstract::The eye's pupil undergoes dynamic changes in diameter associated with cognitive effort, motor activity and emotional state, and can be used to index brain state across mammalian species. Recent studies in head-fixed mice have linked arousal-related pupil dynamics with global neural activity as well as the activity of ...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2016.00200

    authors: Lee CR,Margolis DJ

    更新日期:2016-11-01 00:00:00

  • Social Support Modulates Stress-Related Gene Expression in Various Brain Regions of Piglets.

    abstract::The presence of an affiliative conspecific may alleviate an individual's stress response in threatening conditions. However, the mechanisms and neural circuitry underlying the process of social buffering have not yet been elucidated. Using the domestic pig as an animal model, we examined the effect of a 4-h maternal a...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2016.00227

    authors: Kanitz E,Hameister T,Tuchscherer A,Tuchscherer M,Puppe B

    更新日期:2016-11-29 00:00:00

  • Maladaptive Decision Making in Adults with a History of Adolescent Alcohol use, in a Preclinical Model, Is Attributable to the Compromised Assignment of Incentive Value during Stimulus-Reward Learning.

    abstract::According to recent WHO reports, alcohol remains the number one substance used and abused by adolescents, despite public health efforts to curb its use. Adolescence is a critical period of biological maturation where brain development, particularly the mesocorticolimbic dopamine system, undergoes substantial remodelin...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2017.00134

    authors: Kruse LC,Schindler AG,Williams RG,Weber SJ,Clark JJ

    更新日期:2017-07-25 00:00:00

  • Spatial Working Memory in Male Rats: Pre-Experience and Task Dependent Roles of Dopamine D1- and D2-Like Receptors.

    abstract::The dopaminergic system is known to be involved in working memory processed by several brain regions like prefrontal cortex (PFC), hippocampus, striatum. In an earlier study we could show that Levodopa but not Modafinil enhanced working memory in a T-maze only during the early phase of training (day 3), whereas the la...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2017.00196

    authors: Bezu M,Maliković J,Kristofova M,Engidawork E,Höger H,Lubec G,Korz V

    更新日期:2017-10-13 00:00:00

  • No Evidence for a Relationship Between Hair Testosterone Concentrations and 2D:4D Ratio or Risk Taking.

    abstract::Using a recently developed alternative assay procedure to measure hormone levels from hair samples, we examined the relationships between testosterone, cortisol, 2D:4D ratio, overconfidence and risk taking. A total of 162 (53 male) participants provided a 3 cm sample of hair, a scanned image of their right and left ha...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2018.00030

    authors: Ronay R,van der Meij L,Oostrom JK,Pollet TV

    更新日期:2018-03-05 00:00:00

  • Moral Violations and the Experience of Disgust and Anger.

    abstract::Disgust is a natural defensive emotion that has evolved to protect against potential sources of contamination and has been recently linked to moral judgements in many studies. However, that people often report feelings of disgust when thinking about feces or moral transgressions alike does not necessarily mean that th...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2018.00179

    authors: Oaten M,Stevenson RJ,Williams MA,Rich AN,Butko M,Case TI

    更新日期:2018-08-22 00:00:00

  • A Rat Drinking in the Dark Model for Studying Ethanol and Sucrose Consumption.

    abstract::Background: The intermittent access 2-bottle choice (IA2BC) and drinking in the dark (DID) models were developed for studying rodent binge-like consumption. Traditionally, IA2BC was used with rats and DID with mice. Recently, IA2BC was adapted to study mouse ethanol consumption. However, it is unknown whether DID is s...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2017.00029

    authors: Holgate JY,Shariff M,Mu EW,Bartlett S

    更新日期:2017-02-22 00:00:00

  • Effects of early psychosocial deprivation on the development of memory and executive function.

    abstract::This study investigated the effects of early institutional care on memory and executive functioning. Subjects were participants in the Bucharest Early Intervention Project (BEIP) and included institutionalized children, children with a history of institutionalization who were assigned to a foster care intervention, an...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.08.016.2009

    authors: Bos KJ,Fox N,Zeanah CH,Nelson Iii CA

    更新日期:2009-09-01 00:00:00

  • Genetically-Driven Enhancement of Dopaminergic Transmission Affects Moral Acceptability in Females but Not in Males: A Pilot Study.

    abstract::Moral behavior has been a key topic of debate for philosophy and psychology for a long time. In recent years, thanks to the development of novel methodologies in cognitive sciences, the question of how we make moral choices has expanded to the study of neurobiological correlates that subtend the mental processes invol...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2017.00156

    authors: Pellegrini S,Palumbo S,Iofrida C,Melissari E,Rota G,Mariotti V,Anastasio T,Manfrinati A,Rumiati R,Lotto L,Sarlo M,Pietrini P

    更新日期:2017-08-29 00:00:00

  • Peritraumatic startle response predicts the vulnerability to develop PTSD-like behaviors in rats: a model for peritraumatic dissociation.

    abstract::Peritraumatic dissociation, a state characterized by alteration in perception and reduced awareness of surroundings, is considered to be a risk factor for the development of post-traumatic stress disorder (PTSD). However, the predictive ability of peritraumatic dissociation is questioned for the inconsistent results i...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2014.00014

    authors: Dong X,Li Y

    更新日期:2014-01-28 00:00:00

  • Sleep Deprivation Aggravates Cognitive Impairment by the Alteration of Hippocampal Neuronal Activity and the Density of Dendritic Spine in Isoflurane-Exposed Mice.

    abstract::Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative SD exacerbates cognitive impairment induced by isoflurane. In th...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2020.589176

    authors: Zhang K,Lian N,Ding R,Guo C,Dong X,Li Y,Wei S,Jiao Q,Yu Y,Shen H

    更新日期:2020-11-23 00:00:00

  • Assessing the construct validity of aberrant salience.

    abstract::We sought to validate the psychometric properties of a recently developed paradigm that aims to measure salience attribution processes proposed to contribute to positive psychotic symptoms, the Salience Attribution Test (SAT). The "aberrant salience" measure from the SAT showed good face validity in previous results, ...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.08.058.2009

    authors: Schmidt K,Roiser JP

    更新日期:2009-12-23 00:00:00

  • Corrigendum: Pre-test metyrapone impairs memory recall in fear conditioning tasks: lack of interaction with β-adrenergic activity.

    abstract::[This corrects the article on p. 51 in vol. 9, PMID: 25784866.]. ...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 已发布勘误

    doi:10.3389/fnbeh.2015.00123

    authors: Careaga MB,Tiba PA,Ota SM,Suchecki D

    更新日期:2015-05-13 00:00:00

  • Long-Term Effects of Traumatic Brain Injury on Anxiety-Like Behaviors in Mice: Behavioral and Neural Correlates.

    abstract::Traumatic brain injury (TBI) has been frequently linked to affective disorders such as anxiety and depression. However, much remains to be understood about the underlying molecular and signaling mechanisms that mediate affective dysfunctions following injury. A lack of consensus in animal studies regarding what the af...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2019.00006

    authors: Popovitz J,Mysore SP,Adwanikar H

    更新日期:2019-01-23 00:00:00

  • Adult mouse basal forebrain harbors two distinct cholinergic populations defined by their electrophysiology.

    abstract::We performed whole-cell recordings from basal forebrain (BF) cholinergic neurons in transgenic mice expressing enhanced green fluorescent protein (eGFP) under the control of the choline acetyltransferase promoter. BF cholinergic neurons can be differentiated into two electrophysiologically identifiable subtypes: early...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2012.00021

    authors: Unal CT,Golowasch JP,Zaborszky L

    更新日期:2012-05-08 00:00:00

  • The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness.

    abstract::Cannabinoid compounds may influence both emotional and cognitive processes depending on the level of environmental aversiveness at the time of drug administration. However, the mechanisms responsible for these responses remain to be elucidated. The present experiments investigated the effects induced by the endocannab...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2012.00011

    authors: Campolongo P,Ratano P,Manduca A,Scattoni ML,Palmery M,Trezza V,Cuomo V

    更新日期:2012-03-20 00:00:00

  • Searching for learning-dependent changes in the antennal lobe: simultaneous recording of neural activity and aversive olfactory learning in honeybees.

    abstract::Plasticity in the honeybee brain has been studied using the appetitive olfactory conditioning of the proboscis extension reflex, in which a bee learns the association between an odor and a sucrose reward. In this framework, coupling behavioral measurements of proboscis extension and invasive recordings of neural activ...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2010.00155

    authors: Roussel E,Sandoz JC,Giurfa M

    更新日期:2010-09-01 00:00:00

  • Impairments of working memory in schizophrenia and bipolar disorder: the effect of history of psychotic symptoms and different aspects of cognitive task demands.

    abstract::Comparisons of cognitive impairments between schizophrenia (SZ) and bipolar disorder (BPD) have produced mixed results. We applied different working memory (WM) measures (Digit Span Forward and Backward, Short-delay and Long-delay CPT-AX, N-back) to patients with SZ (n = 23), psychotic BPD (n = 19) and non-psychotic B...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2014.00416

    authors: Frydecka D,Eissa AM,Hewedi DH,Ali M,Drapała J,Misiak B,Kłosińska E,Phillips JR,Moustafa AA

    更新日期:2014-11-28 00:00:00

  • Early life environmental and pharmacological stressors result in persistent dysregulations of the serotonergic system.

    abstract::Dysregulations in the brain serotonergic system and exposure to environmental stressors have been implicated in the development of major depressive disorder. Here, we investigate the interactions between the stress and serotonergic systems by characterizing the behavioral and biochemical effects of chronic stress appl...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2015.00094

    authors: Wong P,Sze Y,Gray LJ,Chang CC,Cai S,Zhang X

    更新日期:2015-04-27 00:00:00

  • Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome.

    abstract::Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), as co-adjuvant to enhance the effects of environmental enrichment (EE) in Ts65Dn mice, a segmenta...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2015.00330

    authors: Catuara-Solarz S,Espinosa-Carrasco J,Erb I,Langohr K,Notredame C,Gonzalez JR,Dierssen M

    更新日期:2015-12-11 00:00:00

  • Disruption of the Glutamate-Glutamine Cycle Involving Astrocytes in an Animal Model of Depression for Males and Females.

    abstract::Background: Women are twice as likely as men to develop major depression. The brain mechanisms underlying this sex disparity are not clear. Disruption of the glutamate-glutamine cycle has been implicated in psychiatric disturbances. This study identifies sex-based impairments in the glutamate-glutamine cycle involving...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2016.00231

    authors: Rappeneau V,Blaker A,Petro JR,Yamamoto BK,Shimamoto A

    更新日期:2016-12-06 00:00:00

  • Reinforcement and inference in cross-situational word learning.

    abstract::Cross-situational word learning is based on the notion that a learner can determine the referent of a word by finding something in common across many observed uses of that word. Here we propose an adaptive learning algorithm that contains a parameter that controls the strength of the reinforcement applied to associati...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2013.00163

    authors: Tilles PF,Fontanari JF

    更新日期:2013-11-19 00:00:00

  • An Additional Prior Retrieval Alters the Effects of a Retrieval-Extinction Procedure on Recent and Remote Fear Memory.

    abstract::Several studies have shown that the isolated retrieval of a consolidated fear memory can induce a labile phase, during which extinction training can prevent the reinstatement, a form of relapse in which fear response to a fear-provoking context returns when a mild shock is presented. However, fear memory retrieval may...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2017.00259

    authors: An X,Yang P,Chen S,Zhang F,Yu D

    更新日期:2018-01-08 00:00:00

  • Glucocorticoid-cholinergic interactions in the dorsal striatum in memory consolidation of inhibitory avoidance training.

    abstract::Extensive evidence indicates that glucocorticoid hormones act in a variety of brain regions to enhance the consolidation of memory of emotionally motivated training experiences. We previously reported that corticosterone, the major glucocorticoid in the rat, administered into the dorsal striatum immediately after inhi...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2012.00033

    authors: Sánchez-Resendis O,Medina AC,Serafín N,Prado-Alcalá RA,Roozendaal B,Quirarte GL

    更新日期:2012-06-22 00:00:00

  • Neonatal stress-induced affective changes in adolescent Wistar rats: early signs of schizophrenia-like behavior.

    abstract::Psychiatric disorders are multifactorial diseases with etiology that may involve genetic factors, early life environment and stressful life events. The neurodevelopmental hypothesis of schizophrenia is based on a wealth of data on increased vulnerability in individuals exposed to insults during the perinatal period. M...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnbeh.2014.00319

    authors: Girardi CE,Zanta NC,Suchecki D

    更新日期:2014-09-10 00:00:00

  • Zebrafish Shoaling, Its Behavioral and Neurobiological Mechanisms, and Its Alteration by Embryonic Alcohol Exposure: A Review.

    abstract::Social cognition and social behaviors are complex phenomena that involve numerous brain areas and underlying neurobiological mechanisms. Embryonic alcohol exposure may lead to the development of Fetal Alcohol Spectrum Disorder (FASD), a disorder that manifests with varying symptoms including abnormal social behavior a...

    journal_title:Frontiers in behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnbeh.2020.572175

    authors: Facciol A,Gerlai R

    更新日期:2020-09-25 00:00:00