The Expression of Ubiquitous Mitochondrial Creatine Kinase Is Downregulated as Prostate Cancer Progression.

abstract：:Purpose Neuroblastoma is an embryonic solid tumor derived from the progenitors of the sympathetic nervous system. More than half of the patients developed metastatic disease at the time of initial diagnosis and had poor outcome with current therapeutic approaches. In recent years, some obligate and facultative anaerob...

journal_title：Journal of Cancer

authors： Ning BT,Yu B,Chan S,Chan JL,Huang JD,Chan GC

更新日期：2017-06-03 00:00:00

abstract：:Tumor progression is often associated with chronic inflammation in the tumor microenvironment, which is mediated by numerous cytokines, chemokines and growth factors produced by cancer and stroma cells. All these mediators support tumor development and immunosuppression in autocrine and/or paracrine ways. Neutralizati...

journal_title：Journal of Cancer

authors： Sevko A,Umansky V

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:We conducted a meta-analysis to evaluate and compare the short- and long-term results of laparoscopic colorectal surgery (LCRS) and conventional open surgery (OCRS) for colorectal cancer (CRC). METHODS:We searched relevant papers published between January 1990 and May 2011. We analyzed the outcomes of each typ...

journal_title：Journal of Cancer

authors： Ohtani H,Tamamori Y,Arimoto Y,Nishiguchi Y,Maeda K,Hirakawa K

更新日期：2011-01-01 00:00:00

abstract：:We use pulmonary interventional procedures for the diagnosis of pulmonary diseases either for benign or malignant lesions. Flexible bronchoscopy with or without radial endobronchial ultrasound, convex-probe endobronchial ultrasound and electromagnetic navigation are procedures performed in centers with experience in d...

journal_title：Journal of Cancer

authors： Hohenforst-Schmidt W,Zarogoulidis P,Huang H,Man YG,Laskou S,Koulouris C,Giannakidis D,Mantalobas S,Florou MC,Amaniti A,Steinheimer M,Sinha A,Freitag L,Turner JF,Browning R,Vogl T,Roman A,Benhassen N,Kesisoglou I,Sap

更新日期：2018-02-12 00:00:00

abstract：:Lung cancer is the deadliest cancer in the world. Angiogenesis plays a crucial role of the incidence, progression, and metastasis in lung cancer. Angiogenesis inhibitors are used to treat non-small cell lung cancer (NSCLC) patients, and the molecular biomarkers are also being assessed to predict treatment response/the...

journal_title：Journal of Cancer

authors： Guo S,Martin MG,Tian C,Cui J,Wang L,Wu S,Gu W

更新日期：2018-03-22 00:00:00

abstract：:Minichromosome Maintenance (MCM) proteins play essential roles in various cancers. We previously reported that MCM7 could be a prognostic biomarker in non-small cell lung cancer (NSCLC). The purpose of current study is to explore roles of other MCM proteins in NSCLC and their correlation with clinico-pathologic parame...

journal_title：Journal of Cancer

authors： Liu YZ,Wang BS,Jiang YY,Cao J,Hao JJ,Zhang Y,Xu X,Cai Y,Wang MR

更新日期：2017-10-09 00:00:00

abstract：:Background: The incidence and mortality rate of gastric cancer has markedly declined over the past few decades, due to the progress and advances in the development of diagnostic and treatment regimens. However, there is still a large portion of patients who are first diagnosed during the advanced stage of gastric canc...

journal_title：Journal of Cancer

authors： Si W,Lyu J,Liu Z,Wang C,Huang J,Jiang L,Ma T

更新日期：2019-10-06 00:00:00

abstract：:Non epithelial ovarian tumors represent a small group of rare gynecological cancers but they have a high incidence in young childbearing women. The recent years fertility preservation surgeries have become a common practice in specific ovarian malignancies when the patients wish to maintain their fertility. Specific t...

journal_title：Journal of Cancer

authors： Thomakos N,Malakasis A,Machairiotis N,Zarogoulidis P,Rodolakis A

更新日期：2018-11-24 00:00:00

abstract：:Philadelphia chromosome-positive (Ph+) leukemia is characterized by reciprocal translocation between chromosomes 9 and 22. The resultant BCR/ABL fusion protein displays constitutive tyrosine kinase activity, leading to the induction of aberrant proliferation and neoplastic transformation. The bone marrow (BM) microenv...

journal_title：Journal of Cancer

authors： Kidan N,Khamaisie H,Ruimi N,Roitman S,Eshel E,Dally N,Ruthardt M,Mahajna J

更新日期：2017-10-23 00:00:00

abstract：:MicroRNA-519d (miR-519d) has been reported to play important roles in tumor development and progression in multiple cancers, either as tumor suppressor or tumor promotor. However, the expression level, biological function and molecular mechanisms of miR-519d in oral squamous cell carcinoma (OSCC) remain unclear. There...

journal_title：Journal of Cancer

authors： Jin Y,Li Y,Wang X,Yang Y

更新日期：2019-06-02 00:00:00

abstract：:Multidrug resistance is a major obstacle to the effective treatment of esophageal carcinoma. It occurs more readily in hypoxia and acidosis microenvironment. TTLL6 is one of Tubulin tyrosine ligase-like family members. In this study, the effect of TTLL6 on the regulation of cisplatin (CDDP) sensitivity was evaluated i...

journal_title：Journal of Cancer

authors： Qiu Y,Wu C,Li J,Tang M,Zhang S,Jing T,Liao Y,Wang H

更新日期：2020-09-30 00:00:00

abstract：:Background: Colorectal cancer (CRC) remains to be one of the most common malignancies worldwide. Various studies have demonstrated that microRNAs (miRs) play a critical role in regulating cancer progression and sensitivity to chemoradiotherapy. miR-1 was found to be aberrantly expressed in CRC. However, it has not bee...

journal_title：Journal of Cancer

authors： Wu Y,Pu N,Su W,Yang X,Xing C

更新日期：2020-06-07 00:00:00

abstract：:Background: The use of PCI in early operable patients with small cell lung cancer (SCLC) is still controversial. Therefore, we conducted a systematic review with meta-analysis to investigate the effects of PCI in resected SCLC patients. Methods: Relevant studies were identified from PubMed and EMBASE databases, the po...

journal_title：Journal of Cancer

authors： Yang Y,Zhang D,Zhou X,Bao W,Ji Y,Sheng L,Cheng L,Chen Y,Du X,Qiu G

更新日期：2018-01-01 00:00:00

abstract：:Background and Aim: Glioblastoma multiforme (GBM) is a highly aggressive brain malignancy that lacks reliable treatments. Resveratrol possesses anti-cancer effects, but its activity against glioblastoma cells is variable for unknown reasons. One mechanism through which anti-cancer drugs exert their effects is oxidativ...

journal_title：Journal of Cancer

authors： Jia B,Zheng X,Wu ML,Tian XT,Song X,Liu YN,Li PN,Liu J

更新日期：2021-01-01 00:00:00

abstract：:There is abundant evidence that long non-coding RNAs play important roles in the development of tumors. In the present study, our main aim was to explore the relationship between lncRNA SNHG7 and human bladder cancer cells, thus finding a novel target for bladder cancer therapy and diagnosis. Expression of lncRNA SNHG...

journal_title：Journal of Cancer

authors： Xu C,Zhou J,Wang Y,Wang A,Su L,Liu S,Kang X

更新日期：2019-01-01 00:00:00

abstract：:Despite advancement in the treatment of diffuse large B-cell lymphoma (DLBCL), many patients tend to relapse or become refractory after initial therapy. Therefore, it is essential to identify novel therapeutic targets and drugs, understand the molecular pathogenesis mechanism of DLBCL, and find ways to prevent and tre...

journal_title：Journal of Cancer

authors： Xu L,Gao X,Yang P,Sang W,Jiao J,Niu M,Liu M,Qin Y,Yan D,Song X,Sun C,Tian Y,Zhu F,Sun X,Zeng L,Li Z,Xu K

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Due to the lack of studies, it remains unclear whether the additional neoadjuvant chemotherapy (NACT) to concurrent chemoradiotherapy (CCRT) is superior to CCRT alone for locoregionally advanced nasopharyngeal carcinoma (NPC). The main objective of this Bayesian network meta-analysis was to determine the eff...

journal_title：Journal of Cancer

authors： Chen YP,Guo R,Liu N,Liu X,Mao YP,Tang LL,Zhou GQ,Lin AH,Sun Y,Ma J

更新日期：2015-07-17 00:00:00

abstract：:The highly conserved Hippo signaling pathway is an important pathway involved in tumorigenesis and development. In previous studies, YAP, the transcription coactivator of Hippo pathway, is found to be highly expressed in many clinical bladder cancer samples. To investigate the function of YAP and its cofactor Mask2 in...

journal_title：Journal of Cancer

authors： Dong L,Lin F,Wu W,Huang W,Cai Z

更新日期：2016-10-23 00:00:00

abstract：:As a crucial event involved in the metastasis and relapse of esophageal cancer, c-Met overexpression has been considered as one of the culprits responsible for the failure in patients who received radiochemotherapy. Since c-Met has been confirmed to be pivotal for cell survival, proliferation and migration, little is ...

journal_title：Journal of Cancer

authors： Chen GZ,Dai WS,Zhu HC,Song HM,Yang X,Wang YD,Min H,Lu Q,Liu S,Sun XC,Zeng XN

更新日期：2017-03-12 00:00:00

abstract：:Tissue-derived RNA, DNA and protein samples become more and more crucial for molecular detection in clinical research, personalized and targeted cancer therapy. This study evaluated how to biobanking colorectal tissues through examining the influences of cold ischemic time and freeze-thaw cycles on RNA, DNA and protei...

journal_title：Journal of Cancer

authors： Fan XJ,Huang Y,Wu PH,Yin XK,Yu XH,Fu XH,Feng LL,Wang YL,Yi HJ,Chen ZT,Yin JX,Zhang DL,Feng WX,Bai SM,Kim T,Mills GB,Lu YL,Wan XB,Wang L

更新日期：2019-08-27 00:00:00

abstract：:Endometrial carcinoma (EC) is the most common malignant tumors in female derived from the endometrial epithelium. Several previous studies have described estrogen receptors (ER), progesterone Receptor (PR) and phosphatase and tensin homolog (PTEN) are associated with clinicopathological factors and prognosis in EC pat...

journal_title：Journal of Cancer

authors： Liang Y,Lin B,Ye Z,Chen S,Yu H,Chen C,Zhang X,Zhou K,Zeng J

更新日期：2020-01-13 00:00:00

abstract：:In this article, the use of different types of thermotherapies to treat breast cancer is reviewed. While hyperthermia is most commonly used as an adjuvant in combination with radiotherapy, chemotherapy, targeted therapy or cryotherapy to enhance the therapeutic effect of these therapies, thermoablation is usually carr...

journal_title：Journal of Cancer

authors： Alphandéry E

更新日期：2014-05-29 00:00:00

abstract：:Background: Carbonic anhydrase 4 (CA4) maintains homeostasis of carbon dioxide and bicarbonate. It is suggested to be a potential prognostic biomarker, while the correlations between CA4 and different cancers are indistinct. Methods: Differential mRNA expression of CA4 among different cancers and corresponding normal ...

journal_title：Journal of Cancer

authors： Xu Y,Xu WH,Shi SN,Yang XL,Ren YR,Zhuang XY,Qu YY,Zhang HL,Zhang XF

更新日期：2020-08-25 00:00:00

abstract：:Background: Although biliary tract cancer (BTC) has a very aggressive nature, some patients maintain a relatively good performance status after failure with first-line treatment of gemcitabine plus cisplatin (GC). Thus, tolerable, feasible, and useful second-line treatments are needed for these patients. We investigat...

journal_title：Journal of Cancer

authors： Kim ST,Oh SY,Lee J,Kang JH,Lee HW,Lee MA,Sohn BS,Hong JH,Park YS,Park JO,Lim HY

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:MALAT-1 is significantly overexpressed in various cancers, suggesting that it might be a potential biomarker of cancer. METHODS:A meta-analysis was performed using microarray data obtained via the Affymetrix Human Genome U133 Plus 2.0 platform found in the Gene Expression Omnibus (GEO) database and data obt...

journal_title：Journal of Cancer

authors： Wang Y,Xue D,Li Y,Pan X,Zhang X,Kuang B,Zhou M,Li X,Xiong W,Li G,Zeng Z,Yang T

更新日期：2016-05-20 00:00:00

abstract：:Purpose: We retrospectively collected consecutive survival data of lung adenosquamous cell carcinoma (ASC) patients with brain metastasis (BM) in our institute and discussed the factors related to prognosis of these patients. Patients and Methods: A total of 42 patients diagnosed as lung ASC with BM between July 1, 20...

journal_title：Journal of Cancer

authors： Pan F,Cui S,Wang W,Gu A,Jiang L

更新日期：2018-09-08 00:00:00

abstract：:Background: Anti-EGFR therapies have been recommended for advanced colorectal cancer (CRC) with wild-type RAS and PIK3CA mutation. However, PIK3CA mutations are a poor prognostic marker and a negative predictor of response to anti-EGFR therapies in RAS wild-type CRC. Therefore, new and advanced treatment strategies ar...

journal_title：Journal of Cancer

authors： Kim JS,Kim JE,Kim K,Lee J,Park JO,Lim HY,Park YS,Kang WK,Kim ST

更新日期：2017-08-22 00:00:00

abstract：:Background & Aims: Primary tumors of colorectal carcinoma (CRC) with liver metastasis might gain some liver-specific characteristics to adapt the liver micro-environment. This study aims to reveal potential liver-like transcriptional characteristics associated with the liver metastasis in primary colorectal carcinoma....

journal_title：Journal of Cancer

authors： Cheng J,Song X,Ao L,Chen R,Chi M,Guo Y,Zhang J,Li H,Zhao W,Guo Z,Wang X

更新日期：2018-04-06 00:00:00

abstract：:Objective: To investigate the development of bronchoscopy in China and compare it with its application in the early 21st century. Methods: The data collection was based on questionnaires. Three hundred and nineteen hospitals, which distributed across 30 provinces and 130 cities, were included in the study. Data about ...

journal_title：Journal of Cancer

authors： Shi D,Li F,Wang K,Kong C,Huang H,Li Q,Jin F,Hu C,Wang C,Shi H,Hu Z,Dong Y,Ning Y,Tsakiridis K,Sapalidis K,Kosmidis C,Vagionas A,Hohenforst-Schmidt W,Freitag L,Turner JF,Drevelegas K,Perdikouri EI,Kovacevic T,

更新日期：2020-07-20 00:00:00

abstract：:Cisplatin-based chemotherapy is the foundation of treatment for major non-small cell lung cancer (NSCLC) patients. However, cisplatin resistance is still a challenging issue, and the molecular mechanisms underlying this resistance remain to be fully explored. CLEC4M, a Ca2+-dependent C-type lectin, has recently been f...

journal_title：Journal of Cancer

authors： Tan LM,Li X,Qiu CF,Zhu T,Hu CP,Yin JY,Zhang W,Zhou HH,Liu ZQ

更新日期：2019-10-19 00:00:00