Endothelial activation and repair during hantavirus infection: association with disease outcome.

abstract：BACKGROUND:The incidence of recurrent herpes zoster (HZ) and the relationship between initial and recurrent HZ are not clear. METHODS:The Miyazaki Dermatologist Society has surveyed ~5000 patients with HZ annually since 1997. A questionnaire regarding HZ and its recurrence was completed by the dermatologists. RESULTS...

journal_title：Open forum infectious diseases

authors： Shiraki K,Toyama N,Daikoku T,Yajima M,Miyazaki Dermatologist Society.

更新日期：2017-01-28 00:00:00

abstract：:Background.  First- and second-generation smallpox vaccines are contraindicated in individuals infected with human immunodeficiency virus (HIV). A new smallpox vaccine is needed to protect this population in the context of biodefense preparedness. The focus of this study was to compare the safety and immunogenicity of...

journal_title：Open forum infectious diseases

authors： Overton ET,Stapleton J,Frank I,Hassler S,Goepfert PA,Barker D,Wagner E,von Krempelhuber A,Virgin G,Meyer TP,Müller J,Bädeker N,Grünert R,Young P,Rösch S,Maclennan J,Arndtz-Wiedemann N,Chaplin P

更新日期：2015-05-05 00:00:00

abstract：:We report a family who acquired acute toxoplasmosis after a trip to Central America. One member developed severe clinical manifestations including bilateral chorioretinitis, hepatitis, and myocarditis requiring therapy. Symptomatic acute toxoplasmosis is unusual and possesses a diagnostic challenge. We discuss the cli...

journal_title：Open forum infectious diseases

authors： Henao-Martínez AF,Franco-Paredes C,Palestine AG,Montoya JG

更新日期：2018-03-09 00:00:00

abstract：Background:Patients heterozygous for mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more susceptible to respiratory infections than the general population. Methods :We conducted a retrospective case-control study using health insurance claims. We identified patients as either h...

journal_title：Open forum infectious diseases

authors： Polgreen PM,Brown GD,Hornick DB,Ahmad F,London B,Stoltz DA,Comellas AP

更新日期：2018-11-01 00:00:00

abstract：Background:Patients with chronic hepatitis C virus (HCV) infection and active or previous hepatitis B virus (HBV) are at risk of HBV reactivation (HBV-R) during direct-acting antiviral (DAA) therapy. Recent reports suggest that HBV-R may even occur several months after completion of DAA therapy. The aim of this study w...

journal_title：Open forum infectious diseases

authors： Mücke MM,Mücke VT,Peiffer KH,Sarrazin C,Zeuzem S,Berger A,Vermehren J

更新日期：2018-12-15 00:00:00

abstract：:Peritoneal dialysis (PD)-associated peritonitis constitutes a major complication associated with the procedure. PD-associated peritonitis caused by nontuberculous mycobacteria, usually as a result of an infection related to the PD catheter, has been reported in adults and is associated with significant complications a...

journal_title：Open forum infectious diseases

authors： Imam O,Al-Zubaidi K,Janahi M,Imam A,Leghrouz B,Dobson S,Sundararaju S,Tsui KM,Hasan MR,Perez-Lopez A

更新日期：2020-11-27 00:00:00

abstract：:Symptomatic acute HCV infection and interferon lambda 4 (IFNL4) genotypes are important predictors of spontaneous viral clearance. Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acute hepatitis C virus...

journal_title：Open forum infectious diseases

authors： Page K,Mirzazadeh A,Rice TM,Grebely J,Kim AY,Cox AL,Morris MD,Hellard M,Bruneau J,Shoukry NH,Dore GJ,Maher L,Lloyd AR,Lauer G,Prins M,McGovern BH

更新日期：2016-02-08 00:00:00

abstract：Background:Staphylococcus aureus (SA) bacteremia often requires a long treatment duration with antibiotics to prevent relapse due to the ability of SA to establish reservoirs of infection in sites such as heart and bone. These metastatic sites of infection cannot be serially sampled to monitor the clearance of SA infec...

journal_title：Open forum infectious diseases

authors： Gutierrez J,Guimaraes AO,Lewin-Koh N,Berhanu A,Xu M,Cao Y,Kim J,Yan D,Chang JK,Dinoso JB,Koss CA,Clemenzi-Allen A,Chambers HF,Peck MC,Baruch A,Rosenberger CM

更新日期：2019-02-26 00:00:00

abstract：:Because of concerns about possible emergence of artemisinin resistance strains of Plasmodium falciparum in mining areas of the interior of Guyana, a 7-day artesunate trial was conducted from March to December 2014. The day-3 parasite clearance rate, the efficacy of artesunate at day 28, and polymorphism of Kelch 13 (P...

journal_title：Open forum infectious diseases

authors： Rahman R,Martin MJ,Persaud S,Ceron N,Kellman D,Musset L,Carter KH,Ringwald P

更新日期：2016-08-30 00:00:00

abstract：:We developed an open-access, Excel-based model simulating currently recommended and alternative algorithms for adult HIV testing as a preliminary investigation of trade-offs between accuracy and costs. Despite higher costs, simpler HIV testing algorithms incorporating point of care nucleic acid testing may improve out...

journal_title：Open forum infectious diseases

authors： Neilan AM,Cohn JE,Lemaire JF,Sacks E,Alban R,Freedberg KA,Walensky RP,Ciaranello AL

更新日期：2018-08-29 00:00:00

abstract：Background:Washington, DC, has one of the highest rates of HIV infection in the United States. Sexual intercourse is the leading mode of HIV transmission, and sexually transmitted infections (STIs) are a risk factor for HIV acquisition and transmission. Methods:We evaluated the incidence and demographic factors associ...

journal_title：Open forum infectious diseases

authors： Lucar J,Hart R,Rayeed N,Terzian A,Weintrob A,Siegel M,Parenti DM,Squires LE,Williams R,Castel AD,Benator DA,DC Cohort Executive Committee .

更新日期：2018-01-24 00:00:00

abstract：:Interpretive criteria for in vitro susceptibility testing criteria, "susceptibility breakpoints," underpin the evaluation and selection of antimicrobial regimens. However, despite their strengths, susceptibility breakpoints are a relatively blunt instrument employed to address an extremely complex question-what is the...

journal_title：Open forum infectious diseases

authors： Bader JC,Lakota EA,Andes DR,Rubino CM,Ambrose PG,Bhavnani SM

更新日期：2018-10-31 00:00:00

abstract：:Burkholderia pseudomallei and Burkholderia cepacia complex are poorly studied in Mexico. The genotypic analysis of 38 strains isolated from children with pneumonia were identified and showed that both Burkholderia groups were present in patients. From our results, it is plausible to suggest that new species are among ...

journal_title：Open forum infectious diseases

authors： Meza-Radilla G,Mendez-Canarios A,Xicohtencatl-Cortes J,Escobedo-Guerra MR,Torres AG,Ibarra JA,Estrada-de Los Santos P

更新日期：2019-01-18 00:00:00

abstract：Background:Internal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents' ability to diagnose tuberculosis is important. Methods:Internal medicine resident knowledg...

journal_title：Open forum infectious diseases

authors： Chida N,Brown C,Mathad J,Carpenter K,Nelson G,Schechter MC,Giles N,Rebolledo PA,Ray S,Fabre V,Cantillo DS,Longworth S,Amorosa V,Petrauskis C,Boulanger C,Cain N,Gupta A,McKenzie-White J,Bollinger R,Melia MT

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:Intra-abdominal infections (IAI) constitute a common reason for hospitalization. However, there is lack of standardization in empiric management of (1) anaerobes, (2) enterococci, (3) fungi, and (4) multidrug-resistant organisms (MDRO). The recommendation is to institute empiric coverage for some of these or...

journal_title：Open forum infectious diseases

authors： Marcus G,Levy S,Salhab G,Mengesha B,Tzuman O,Shur S,Burke E,Mayeda RC,Cochavi L,Perluk I,Zaidenstein R,Lazarovitch T,Dadon M,Marchaim D

更新日期：2016-12-20 00:00:00

abstract：Background:In human immunodeficiency virus (HIV) treatment, tenofovir alafenamide (TAF) is associated with greater increases in all fasting cholesterol subgroups compared with tenofovir disoproxil fumarate (TDF). Because lipid abnormalities may contribute to cardiovascular morbidity and mortality, cardiovascular risk a...

journal_title：Open forum infectious diseases

authors： Huhn GD,Shamblaw DJ,Baril JG,Hsue PY,Mills BL,Nguyen-Cleary T,McCallister S,Das M

更新日期：2019-11-11 00:00:00

abstract：Background:Irritable bowel syndrome (IBS) is a chronic and debilitating functional gastrointestinal disorder affecting 9%-23% of the population across the world. The relative efficacy of fecal microbiota transplantation (FMT) on IBS symptoms was demonstrated in a double-blind, randomized study. Methods:We describe the...

journal_title：Open forum infectious diseases

authors： Hocquart M,Pham T,Kuete E,Tomei E,Lagier JC,Raoult D

更新日期：2019-10-14 00:00:00

abstract：Background:Identification of HIV infection at the early stage is valuable for patient management, for prevention, and for research purposes. In practice, identification of a recent HIV infection at diagnosis proves challenging after HIV antibody seroconversion but can be suspected using Western blots (WBs) or immunoblo...

journal_title：Open forum infectious diseases

authors： Stefic K,Mahjoub N,Desouche C,Néré ML,Thierry D,Delaugerre C,Barin F,Chaix ML

更新日期：2020-04-21 00:00:00

abstract：Background:Direct acting antiviral hepatitis C virus (HCV) therapies are highly effective but costly. Wider adoption of an 8-week ledipasvir/sofosbuvir treatment regimen could result in significant savings, but may be less efficacious compared with a 12-week regimen. We evaluated outcomes under a constrained budget and...

journal_title：Open forum infectious diseases

authors： Morgan JR,Kim AY,Naggie S,Linas BP

更新日期：2017-12-08 00:00:00

abstract：Background:The US Food and Drug Administration issued an Emergency Use Authorization for remdesivir use in patients with severe COVID-19. Methods:We utilized data from 2 quaternary acute care hospitals. The outcomes of interest were the impact of remdesivir on in-hospital death by day 28 and time to recovery, clinical...

journal_title：Open forum infectious diseases

authors： Kalligeros M,Tashima KT,Mylona EK,Rybak N,Flanigan TP,Farmakiotis D,Beckwith CG,Sanchez M,Neill M,Johnson JE,Garland JM,Aung S,Byrd KM,O'Brien T,Pandita A,Aridi J,Macias Gil R,Larkin J,Shehadeh F,Mylonakis E

更新日期：2020-08-06 00:00:00

abstract：Background:Coagulation activity among persons with HIV is associated with end-organ disease risk, but the pathogenesis is not well characterized. We tested a hypothesis that hypercoagulation contributes to disease risk, in part, via upregulation of inflammation. Methods:Treatment effects of edoxaban (30 mg), a direct ...

journal_title：Open forum infectious diseases

authors： Baker JV,Wolfson J,Peterson T,Mooberry M,Gissel M,Mystakelis H,Henderson MW,Garcia-Myers K,Rhame FS,Schacker TW,Brummel-Ziedins KE,Sereti I,Key NS,Tracy RP

更新日期：2020-02-01 00:00:00

abstract：Background:The Short Physical Performance Battery (SPPB) is a well regarded physical functioning assessment including balance, gait speed, and chair-stand tests. Its use has not been widely assessed in human immunodeficiency virus (HIV) care. We evaluated the feasibility of integrating the SPPB into care of aging peopl...

journal_title：Open forum infectious diseases

authors： Crane HM,Miller ME,Pierce J,Willig AL,Case ML,Wilkin AM,Brown S,Asirot MG,Fredericksen RJ,Saag MS,Landay AL,High KP

更新日期：2019-03-11 00:00:00

abstract：BACKGROUND:Human immunodeficiency virus controllers (HICs) form a heterogeneous group of patients with regard to formal definitions, immunologic characteristics, and changes over time in viral load. PATIENTS AND METHODS:The HICs with undetectable viral load ([uHICs] ie, for whom a viral load had never been detected wi...

journal_title：Open forum infectious diseases

authors： Canouï E,Lécuroux C,Avettand-Fenoël V,Gousset M,Rouzioux C,Saez-Cirion A,Meyer L,Boufassa F,Lambotte O,Noël N,and the ANRS CO21 CODEX Study Group.

更新日期：2017-04-03 00:00:00

abstract：Background:Clinical features of Lyme disease (LD) range from localized skin lesions to serious disseminated disease. Information on risk factors for Lyme arthritis, facial palsy, carditis, and meningitis is limited but could facilitate disease recognition and elucidate pathophysiology. Methods:Patients from high-incid...

journal_title：Open forum infectious diseases

authors： Kwit NA,Nelson CA,Max R,Mead PS

更新日期：2017-11-18 00:00:00

abstract：Background:Although existing literature supports durations of 5-7 days for skin and soft tissue infections (SSTIs), longer durations are commonly used. Obesity and heart failure (HF) have been associated with increased risk for treatment failure of SSTIs; however, whether prolonged antibiotic durations reduce the risk ...

journal_title：Open forum infectious diseases

authors： Ihm C,Sutton JD,Timbrook TT,Spivak ES

更新日期：2019-05-07 00:00:00

abstract：Background:Recent studies have favored the use of cefazolin over nafcillin for the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. The clinical influence of the cefazolin inoculum effect (CzIE) in the effectiveness of cephalosporins for severe MSSA infections has not been evaluated. Metho...

journal_title：Open forum infectious diseases

authors： Miller WR,Seas C,Carvajal LP,Diaz L,Echeverri AM,Ferro C,Rios R,Porras P,Luna C,Gotuzzo E,Munita JM,Nannini E,Carcamo C,Reyes J,Arias CA

更新日期：2018-05-23 00:00:00

abstract：Background:Few studies have compared the yield of reverse transcription polymerase chain reaction (RT-PCR) assays in nasopharyngeal swabs, oropharyngeal swabs, and sputum for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. Methods:We conducted an observational study in Beijing Ditan Hospital, C...

journal_title：Open forum infectious diseases

authors： Zhang H,Chen M,Zhang Y,Wen J,Wang Y,Wang L,Guo J,Liu C,Li D,Wang Y,Bai J,Gao G,Wang S,Yang D,Yu F,Yan L,Wan G,Zhang F

更新日期：2020-08-26 00:00:00

abstract：:Background.  Cryptococcal meningitis is a leading cause of death in people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome. The World Health Organizations recommends pre-antiretroviral treatment (ART) cryptococcal antigen (CRAG) screening in persons with CD4 below 100 cells/µL. We as...

journal_title：Open forum infectious diseases

authors： Letang E,Müller MC,Ntamatungiro AJ,Kimera N,Faini D,Furrer H,Battegay M,Tanner M,Hatz C,Boulware DR,Glass TR

更新日期：2015-04-02 00:00:00

abstract：:In this study, we report the case of a patient infected with human immunodeficiency virus (HIV)-1 who developed ataxia and neurocognitive impairment due to viral escape within the central nervous system (CNS) with a multidrug-resistant HIV-1 despite long-term viral suppression in plasma. Antiretroviral therapy optimiz...

journal_title：Open forum infectious diseases

authors： Béguelin C,Vázquez M,Bertschi M,Yerly S,de Jong D,Gutbrod K,Rauch A,Cusini A

更新日期：2015-12-28 00:00:00

abstract：Background:Hydatid disease is a severe health problem in endemic areas. In recent years, the incidence of this disease in China has been increasing. As the imaging characteristics of pancreatic echinococcosis (PE) are similar to those of cystic diseases, such as cysts, tuberculosis, and tumors, PE is often misdiagnosed...

journal_title：Open forum infectious diseases

authors： Gou L,Gao F,Tiheiran M,Guo H

更新日期：2020-04-03 00:00:00