Intracerebral hemorrhage after intravenous thrombolysis in patients with cerebral microbleeds and cardiac myxoma.

abstract：:Traumatic brain injury resulting from exposure to blast overpressure (BOP) is associated with neuropathology including impairment of the blood-brain barrier (BBB). This study examined the effects of repeated exposure to primary BOP and post-blast treatment with an antioxidant, N-acetylcysteine amide (NACA) on the inte...

journal_title：Frontiers in neurology

authors： Kawoos U,Abutarboush R,Zarriello S,Qadri A,Ahlers ST,McCarron RM,Chavko M

更新日期：2019-06-26 00:00:00

abstract：Objective:Vestibular signals are involved in higher cortical functions like spatial orientation and its disorders. Vestibular dysfunction contributes, for example, to spatial neglect which can be transiently improved by caloric stimulation. The exact roles and mechanisms of the vestibular and visual systems for the rec...

journal_title：Frontiers in neurology

authors： Conrad J,Boegle R,Ertl M,Brandt T,Dieterich M

更新日期：2018-03-02 00:00:00

abstract：:Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) are neurodegenerative diseases with characteristic inflammatory demyelination in the central nervous system, including the optic nerve. Neuronal and axonal damage is considered to be the main cause of long-term disability in p...

journal_title：Frontiers in neurology

authors： Quinn TA,Dutt M,Shindler KS

更新日期：2011-08-02 00:00:00

abstract：:Background: Non-invasive brain-computer interfaces (BCI) represent an emerging technology for enabling persons with impaired or lost grasping and reaching functions due to high spinal cord injury (SCI) to control assistive devices. A major drawback of BCIs is a high rate of false classifications. The robustness and pe...

journal_title：Frontiers in neurology

authors： Keyl P,Schneiders M,Schuld C,Franz S,Hommelsen M,Weidner N,Rupp R

更新日期：2019-01-31 00:00:00

abstract：:Background: Palliative care in Parkinson's Disease (PD) patients considerably differs from palliative care in oncology patients. Integrated care models are a concept to support patients and improve management of PD symptoms. However, it is not known if the access to PD patients at the end of life can be achieved throu...

journal_title：Frontiers in neurology

authors： Eggers C,Dano R,Schill J,Fink GR,Timmermann L,Voltz R,Golla H,Lorenzl S

更新日期：2018-07-30 00:00:00

abstract：:Therapeutic hypothermia (HT) is a currently accepted treatment for neonatal asphyxia and is a promising strategy in adult stroke therapy. We previously reported that acute administration of docosahexaenoic acid (DHA) triglyceride emulsion (tri-DHA) protects against hypoxic-ischemic (HI) injury in neonatal mice. We que...

journal_title：Frontiers in neurology

authors： Manual Kollareth DJ,Zirpoli H,Ten VS,Deckelbaum RJ

更新日期：2021-01-15 00:00:00

abstract：:Myasthenia gravis (MG) is the most common autoimmune disorder affecting the neuromuscular junction, characterized by skeletal muscle weakness and fatigability. It is caused by autoantibodies targeting proteins of the neuromuscular junction; ~85% of MG patients have autoantibodies against the muscle acetylcholine recep...

journal_title：Frontiers in neurology

authors： Lazaridis K,Tzartos SJ

更新日期：2020-11-30 00:00:00

abstract：:We report a case of spontaneous intracerebral hemorrhage (sICH) due to delta storage pool disease in a 60-year-old female on a serotonin-norepinephrine reuptake inhibitor (SNRI). Increased susceptibility to SNRI-effects on hemostasis was due to a genetic disposition mediated by a polymorphism of the SLC6A4 gene coding...

journal_title：Frontiers in neurology

authors： Leibetseder A,Wagner J,Tomasits J,Haring HP,Hutterer M,Trenkler J,von Oertzen TJ

更新日期：2019-11-26 00:00:00

abstract：:Functional magnetic resonance imaging studies suggest that different subcortico-cortical circuits control different aspects of Parkinsonian rest tremor. The basal ganglia were proposed to drive tremor onset, and the cerebellum was suggested to be responsible for tremor maintenance ("dimmer-switch" hypothesis). Althoug...

journal_title：Frontiers in neurology

authors： Hirschmann J,Abbasi O,Storzer L,Butz M,Hartmann CJ,Wojtecki L,Schnitzler A

更新日期：2019-03-07 00:00:00

abstract：:Qualitative clinical assessments of the recovery of awareness after severe brain injury require an assessor to differentiate purposeful behavior from spontaneous behavior. As many such behaviors are minimal and inconsistent, behavioral assessments are susceptible to diagnostic errors. Advanced neuroimaging tools can b...

journal_title：Frontiers in neurology

authors： Rupawala M,Dehghani H,Lucas SJE,Tino P,Cruse D

更新日期：2018-05-22 00:00:00

abstract：:Objective: The peak-to-peak amplitude of the p13-n23 wave in cervical vestibular evoked myogenic potential can increase after furosemide administration in patients with Meniere's disease [furosemide-loading VEMP (FVEMP) testing]. The examination is used to test for the presence of endolymphatic hydrops; we investigate...

journal_title：Frontiers in neurology

authors： Seo T,Shiraishi K,Kobayashi T,Fujita T,Saito K,Doi K

更新日期：2018-08-03 00:00:00

abstract：:Autism Spectrum Disorders comprise conditions that may affect cognitive development, motor skills, social interaction, communication, and behavior. This set of functional deficits often results in lack of independence for the diagnosed individuals, and severe distress for patients, families, and caregivers. There is a...

journal_title：Frontiers in neurology

authors： Fleury-Teixeira P,Caixeta FV,Ramires da Silva LC,Brasil-Neto JP,Malcher-Lopes R

更新日期：2019-10-31 00:00:00

abstract：:Importance: Coronavirus disease 2019 (COVID-19) is a newly emerging infectious disease that has caused a global pandemic. The presenting symptoms are mainly respiratory symptom, yet studies have reported nervous system involvement in the disease. A systematic review and meta-analysis of these studies are required to u...

journal_title：Frontiers in neurology

authors： Pinzon RT,Wijaya VO,Buana RB,Al Jody A,Nunsio PN

更新日期：2020-05-29 00:00:00

abstract：:Disrupted development of oropharyngeal structures as well as cranial nerve and brainstem circuits may lead to feeding and swallowing difficulties in children with 22q11. 2 deletion syndrome (22q11DS). We previously demonstrated aspiration-based dysphagia during early postnatal life in the LgDel mouse model of 22q11DS ...

journal_title：Frontiers in neurology

authors： Welby L,Caudill H,Yitsege G,Hamad A,Bunyak F,Zohn IE,Maynard T,LaMantia AS,Mendelowitz D,Lever TE

更新日期：2020-01-31 00:00:00

abstract：OBJECTIVE:Our aim was to identify the role of the investigators' knowledge of the patient's history of vestibular symptoms (PVH) in the clinical evaluation of the bedside head-impulse test (bHIT). We hypothesized that this knowledge will reduce uncertainty and improve bHIT accuracy when compared to quantitative analysi...

journal_title：Frontiers in neurology

authors： Helmchen C,Knauss J,Trillenberg P,Frendl A,Sprenger A

更新日期：2017-02-20 00:00:00

abstract：:Background and Purpose: Internal carotid artery stenosis (ICAS)≥70% is a leading cause of ischemic cerebrovascular events (ICVEs). However, a considerable percentage of stroke survivors with symptomatic ICAS (sICAS) have <70% stenosis with a vulnerable plaque. Whether the length of ICAS is associated with high risk of...

journal_title：Frontiers in neurology

authors： Elhfnawy AM,Heuschmann PU,Pham M,Volkmann J,Fluri F

更新日期：2019-04-09 00:00:00

abstract：:The vestibular system plays a crucial role in the multisensory control of balance. When vestibular function is lost, essential tasks such as postural control, gaze stabilization, and spatial orientation are limited and the quality of life of patients is significantly impaired. Currently, there is no effective treatmen...

journal_title：Frontiers in neurology

authors： Perez Fornos A,Guinand N,van de Berg R,Stokroos R,Micera S,Kingma H,Pelizzone M,Guyot JP

更新日期：2014-04-29 00:00:00

abstract：:Migraine is a chronic disease characterized by unilateral, pulsating, and often moderate-to-severe recurrent episodes of headache with nausea and vomiting. It affects approximately 15% of the general population, yet the underlying pathophysiological mechanisms are not fully understood. Optical coherence tomography (OC...

journal_title：Frontiers in neurology

authors： Ascaso FJ,Marco S,Mateo J,Martínez M,Esteban O,Grzybowski A

更新日期：2017-12-13 00:00:00

abstract：:Exposure of the brain to brief, non-harmful seizures can activate protective mechanisms that temporarily generate a damage-refractory state. This process, termed epileptic tolerance, is associated with large-scale down-regulation of gene expression. Polycomb group (PcG) proteins are master controllers of gene silencin...

journal_title：Frontiers in neurology

authors： Reynolds JP,Miller-Delaney SF,Jimenez-Mateos EM,Sano T,McKiernan RC,Simon RP,Henshall DC

更新日期：2015-03-10 00:00:00

abstract：:Increasing evidence suggests an association between gastrointestinal (GI) disorders and susceptibility and progress of Parkinson's disease (PD). Gut-brain axis has been proposed to play important roles in the pathogenesis of PD, though the exact pathophysiologic mechanism has yet to be elucidated. Here, we discuss the...

journal_title：Frontiers in neurology

authors： Chao YX,Gulam MY,Chia NSJ,Feng L,Rotzschke O,Tan EK

更新日期：2020-08-25 00:00:00

abstract：:This study reports the case of an acoustic shock injury (ASI), which did not result in a significant hearing loss, but was followed by manifold chronic symptoms both within (tinnitus, otalgia, tingling in the ear, tension in the ear, and red tympanum) and outside the ears (blocked nose, pain in the neck/temporal regio...

journal_title：Frontiers in neurology

authors： Londero A,Charpentier N,Ponsot D,Fournier P,Pezard L,Noreña AJ

更新日期：2017-08-16 00:00:00

abstract：:With the demographic shift of the global population toward longer life expectancy, the number of people living with Alzheimer's disease (AD) has rapidly expanded and is projected to triple by the year 2050. Current treatments provide symptomatic relief but do not affect the underlying pathology of the disease. Therapi...

journal_title：Frontiers in neurology

authors： Ritter A,Cummings J

更新日期：2015-08-31 00:00:00

abstract：:Objective: To evaluate ocular and cervical vestibular evoked myogenic potentials (oVEMPs and cVEMPs) in patients with solely intracochlear localization of an intralabyrinthine schwannoma (ILS). Study Design: Retrospective analysis of a series of cases. Setting: Monocentric study at a tertiary referral center. Patients...

journal_title：Frontiers in neurology

authors： Fröhlich L,Curthoys IS,Kösling S,Obrist D,Rahne T,Plontke SK

更新日期：2020-10-27 00:00:00

abstract：:Stroke is becoming one of the leading causes of adult disability and death in sub-Saharan African countries. The aim of the present study is to provide an up-to-date account of the clinical and demographic characteristics of patients with stroke admitted to the University of Gondar College of Medicine and Health Scien...

journal_title：Frontiers in neurology

authors： Baye M,Hintze A,Gordon-Murer C,Mariscal T,Belay GJ,Gebremariam AA,Hughes CML

更新日期：2020-05-19 00:00:00

abstract：:Takotsubo cardiomyopathy (TTC) is an acute and reversible cardiac wall motion abnormality of the left myocardium. Although many studies focused on etiology, diagnostic and treatment of TTC, precise clinical guidelines on TTC are not available. Research revealed emotional and physical triggering factors of TTC and emph...

journal_title：Frontiers in neurology

authors： Buchmann SJ,Lehmann D,Stevens CE

更新日期：2019-08-22 00:00:00

abstract：:Autoimmune encephalitis often causes acute psychiatric symptoms and epileptic seizures. However, it is becoming increasingly clear that depending on the target antigen both symptoms and disease severity may vary. Furthermore, the identification and characterization of antibody subtypes are highly relevant for personal...

journal_title：Frontiers in neurology

authors： Edwin Thanarajah S,Prüss H,Warnke C,Barbe MT,Schroeter M,Fink GR,Onur OA

更新日期：2019-03-05 00:00:00

abstract：:Background: Elderly patients account for 30% of acute ischemic stroke (AIS) but are under-represented in randomized controlled trials of endovascular thrombectomy (EVT). Meta-analysis of "real world" studies evaluating 90-day outcomes in elderly patients ≥80 years have been limited to small numbers undergoing EVT with...

journal_title：Frontiers in neurology

authors： Sharobeam A,Cordato DJ,Manning N,Cheung A,Wenderoth J,Cappelen-Smith C

更新日期：2019-03-20 00:00:00

abstract：:Cyclooxygenase (COX)-2 and matrix metalloproteinase (MMP)-9 are two crucial mediators contributing to blood-brain barrier (BBB) damage during cerebral ischemia. However, it is not known whether MMP-9 activation is involved in COX-2-mediated BBB disruption in ischemic stroke. In this study, we hypothesized that genetic...

journal_title：Frontiers in neurology

authors： Yang C,Yang Y,DeMars KM,Rosenberg GA,Candelario-Jalil E

更新日期：2020-08-20 00:00:00

abstract：:Background and Purpose: Patients with large vessel occlusion stroke (LVOS) need to be rapidly identified and transferred to comprehensive stroke centers (CSC). However, previous pre-hospital strategy remains challenging. We aimed to develop a modified scale to better predict LVOS. Methods: We retrospectively reviewed ...

journal_title：Frontiers in neurology

authors： Gong X,Chen Z,Shi F,Zhang M,Xu C,Zhang R,Lou M

更新日期：2019-04-17 00:00:00

abstract：:Background: Spontaneous use of the more-affected arm is a meaningful indicator of stroke recovery. The Bilateral Arm Reaching Test (BART) was previously developed to quantify arm use by measuring arm choice to targets projected over a horizontal hemi-workspace. In order to improve clinical validity, we constrained the...

journal_title：Frontiers in neurology

authors： Kim S,Park H,Han CE,Winstein CJ,Schweighofer N

更新日期：2018-10-22 00:00:00