Conditioned fear associated phenotypes as robust, translational indices of trauma-, stressor-, and anxiety-related behaviors.

abstract：:Anhedonia is a condition in which the capacity of experiencing pleasure is totally or partially lost, and it refers to both a state symptom in various psychiatric disorders and a personality trait. It has a putative neural substrate, originating in the dopaminergic mesolimbic and mesocortical reward circuit. Anhedonia...

journal_title：Frontiers in psychiatry

authors： Hatzigiakoumis DS,Martinotti G,Giannantonio MD,Janiri L

更新日期：2011-03-17 00:00:00

abstract：:Objective: We aimed to determine the prevalence of burnout among hospital healthcare workers in Libya during the coronavirus disease (COVID-19) pandemic and civil war. Methods: A cross-sectional study was conducted from April 18 to May 2, 2020 among Libyan healthcare workers. Data on participant characteristics were c...

journal_title：Frontiers in psychiatry

authors： Elhadi M,Msherghi A,Elgzairi M,Alhashimi A,Bouhuwaish A,Biala M,Abuelmeda S,Khel S,Khaled A,Alsoufi A,Elmabrouk A,Alshiteewi FB,Hamed TB,Alhadi B,Alhaddad S,Elhadi A,Zaid A

更新日期：2020-12-11 00:00:00

abstract：:According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated with the positive and negative symptoms of schizophrenia. However, the underlying mechanisms responsible for the changes in glutamate transmission ...

journal_title：Frontiers in psychiatry

authors： Mei YY,Wu DC,Zhou N

更新日期：2018-11-06 00:00:00

abstract：Background:The worldwide coronavirus outbreak has put hospital workers under extreme stress with possible mental health problems. In this context, we decided to rapidly design and implement a psychological support system for all hospital workers in Paris during the Covid-19 outbreak. Methods:We built a hotline in 3 da...

journal_title：Frontiers in psychiatry

authors： Geoffroy PA,Le Goanvic V,Sabbagh O,Richoux C,Weinstein A,Dufayet G,Lejoyeux M

更新日期：2020-05-28 00:00:00

abstract：:Objective: To analyze the predictive value of antepartum vulnerability factors, such as social support, coping, history of psychiatric disease, and fear of childbirth, and intrapartum events on the development of symptoms of postpartum posttraumatic stress disorder (PP-PTSD) in women with a traumatic childbirth experi...

journal_title：Frontiers in psychiatry

authors： van Heumen MA,Hollander MH,van Pampus MG,van Dillen J,Stramrood CAI

更新日期：2018-07-31 00:00:00

abstract：:Introduction: Chronic recreational methamphetamine use causes dopaminergic neurotoxicity, which has been linked to impairments in executive functioning. Within this functional domain, response selection and the resolution of associated conflicts have repeatedly been demonstrated to be strongly modulated by dopamine. Y...

journal_title：Frontiers in psychiatry

authors： Bensmann W,Ernst J,Rädle M,Opitz A,Beste C,Stock AK

更新日期：2019-11-19 00:00:00

abstract：:Increasing evidence suggests that binge eating-related disorders could be related to addiction-like eating patterns due to the addictive potential of hyperpalatable foods. Subsequently, important implications have been derived for treatment of those disorders and even political actions. However, studies on the prevale...

journal_title：Frontiers in psychiatry

authors： Meule A

更新日期：2011-11-03 00:00:00

abstract：:New models of care aimed at reinforcing the outpatient sector have been introduced in Germany over the last few years. Initially, a subscription-based model ("integrated care") was introduced in 2012 in the Immanuel Klinik Rüdersdorf, wherein patients had to actively subscribe to the integrated care program. This inte...

journal_title：Frontiers in psychiatry

authors： Wullschleger A,Wosniok W,Timm J,Heinze M

更新日期：2017-10-05 00:00:00

abstract：:Suicidality is highly prevalent in patients at clinical high risk (CHR) for psychosis. Childhood adversities and trauma are generally predictive of suicidality. However, the differential effects of adversity/trauma-domains and CHR-criteria, i.e., ultra-high risk and basic symptom criteria, on suicidality remain unclea...

journal_title：Frontiers in psychiatry

authors： Schmidt SJ,Schultze-Lutter F,Bendall S,Groth N,Michel C,Inderbitzin N,Schimmelmann BG,Hubl D,Nelson B

更新日期：2017-11-20 00:00:00

abstract：:Eating disorders (EDs) are serious psychopathologies characterized by a persistent disturbance in eating or eating-related behavior. Studies have shown EDs' detrimental consequences not only for patients, but also for their families. Nevertheless, a specific group that has so far been neglected, in both the research a...

journal_title：Frontiers in psychiatry

authors： Maon I,Horesh D,Gvion Y

更新日期：2020-06-30 00:00:00

abstract：:Depression has been associated with peripheral inflammatory processes and alterations in cellular immunity. Growing evidence suggests that immunological alterations may neither be necessary nor sufficient to induce depression in general, but seem to be associated with specific features. Using baseline data from the Ou...

journal_title：Frontiers in psychiatry

authors： Euteneuer F,Dannehl K,Del Rey A,Engler H,Schedlowski M,Rief W

更新日期：2017-11-23 00:00:00

abstract：:Major depression is a psychiatric disorder with high prevalence in the general population, with increasing expression in adolescence, about 14% in young people. Frequently, it presents as a chronic condition, showing no remission even after several pharmacological treatments and persisting in adult life. Therefore, di...

journal_title：Frontiers in psychiatry

authors： Galvão-Coelho NL,Galvão ACM,da Silva FS,de Sousa MBC

更新日期：2017-09-21 00:00:00

abstract：:About 15% of mothers suffer from postpartum psychiatric disorders, such as depression, anxiety, or psychosis. Numerous studies have shown maternal caregiving behavior to be negatively affected under these circumstances. The current study sets out to shed light on specific caregiving behaviors of affected mothers in th...

journal_title：Frontiers in psychiatry

authors： Heinisch C,Galeris MG,Gabler S,Simen S,Junge-Hoffmeister J,Fößel J,Spangler G

更新日期：2019-07-22 00:00:00

abstract：:Objective: Selective serotonin reuptake inhibitors like sertraline have been shown in observational studies and anecdotal reports to improve language development in young children with fragile X syndrome (FXS). A previous controlled trial of sertraline in young children with FXS found significant improvement in expres...

journal_title：Frontiers in psychiatry

authors： Potter LA,Scholze DA,Biag HMB,Schneider A,Chen Y,Nguyen DV,Rajaratnam A,Rivera SM,Dwyer PS,Tassone F,Al Olaby RR,Choudhary NS,Salcedo-Arellano MJ,Hagerman RJ

更新日期：2019-11-06 00:00:00

abstract：:There is accruing evidence of cerebellar abnormalities in schizophrenia. The theory of cognitive dysmetria considers cerebellar dysfunction a key component of schizophrenia. Delay eyeblink conditioning (EBC), a cerebellar-dependent translational probe, is a behavioral index of cerebellar integrity. The circuitry under...

journal_title：Frontiers in psychiatry

authors： Kent JS,Bolbecker AR,O'Donnell BF,Hetrick WP

更新日期：2015-12-18 00:00:00

abstract：BACKGROUND:The treatment of cocaine-dependent individuals (CDI) is substantially challenged by high drop-out rates, raising questions regarding contributing factors. Recently, a number of studies have highlighted the potential of greater focus on the clinical significance of neurocognitive impairments in treatment-seek...

journal_title：Frontiers in psychiatry

authors： Stevens L,Betanzos-Espinosa P,Crunelle CL,Vergara-Moragues E,Roeyers H,Lozano O,Dom G,Gonzalez-Saiz F,Vanderplasschen W,Verdejo-García A,Pérez-García M

更新日期：2013-11-15 00:00:00

abstract：:Virtual reality (VR) offers children with autism spectrum disorder (ASD) an inexpensive and motivating medium to learn and practice skills in a personalized, controlled, and safe setting; however, outcomes of VR interventions can vary widely. In particular, there is a need to understand the predictors of VR experience...

journal_title：Frontiers in psychiatry

authors： Malihi M,Nguyen J,Cardy RE,Eldon S,Petta C,Kushki A

更新日期：2020-08-04 00:00:00

abstract：:Mental imagery, seeing with the mind's eyes, can induce stronger positive as well as negative affect compared to verbal processing. Given this emotion-amplifying effect, it appears likely that mental images play an important role in affective disorders. According to the subcomponents model of depression, depressed moo...

journal_title：Frontiers in psychiatry

authors： Görgen SM,Joormann J,Hiller W,Witthöft M

更新日期：2015-07-07 00:00:00

abstract：Background:Depressive patients show less altruistic behavior. While, older adults present higher tendencies for altruism than younger adults. Depression and age are two of the influencing factors of altruism, kynurenine (KYN), and its metabolites. However, the characteristics of altruism in late-life depression (LLD) a...

journal_title：Frontiers in psychiatry

authors： Wu Y,Mai N,Weng X,Liang J,Ning Y

更新日期：2020-04-30 00:00:00

abstract：:Background: Treatment of borderline personality disorder (BPD) in publicly funded mental health services generally use approaches based on medical interventions and generic case management. Specific psychological therapies developed for BPD may be more effective but have rarely been evaluated in routine clinical pract...

journal_title：Frontiers in psychiatry

authors： Carlyle D,Green R,Inder M,Porter R,Crowe M,Mulder R,Frampton C

更新日期：2020-11-12 00:00:00

abstract：:Impaired manual dexterity is commonly observed in schizophrenia. However, a quantitative description of key sensorimotor components contributing to impaired dexterity is lacking. Whether the key components of dexterity are differentially affected and how they relate to clinical characteristics also remains unclear. We...

journal_title：Frontiers in psychiatry

authors： Térémetz M,Carment L,Brénugat-Herne L,Croca M,Bleton JP,Krebs MO,Maier MA,Amado I,Lindberg PG

更新日期：2017-07-10 00:00:00

abstract：:What is the role and value of pleasure in addiction? Foddy and Savulescu (1) have claimed that substance use is just pleasure-oriented behavior. They describe addiction as "strong appetites toward pleasure" and argue that addicts suffer in significant part because of strong social and moral disapproval of lives domina...

journal_title：Frontiers in psychiatry

authors： Kennett J,Matthews S,Snoek A

更新日期：2013-09-25 00:00:00

abstract：:There is an increasing awareness that autoimmune diseases can present with neuropsychiatric manifestations. We present the case of a 17-year-old female requiring psychiatric hospitalization for obsessive-compulsive disorder and major depressive disorder with mixed affective features, who was subsequently diagnosed wit...

journal_title：Frontiers in psychiatry

authors： Ong LTC,Galambos G,Brown DA

更新日期：2017-07-11 00:00:00

abstract：:Alcohol is one of the leading risk factors for global disease burden and overconsumption leads to a wide variety of negative consequences in everyday life. Digital interventions have shown small positive effects in contributing to reductions in problematic use. Specific research on smartphone apps is sparse and the fe...

journal_title：Frontiers in psychiatry

authors： Berman AH,Molander O,Tahir M,Törnblom P,Gajecki M,Sinadinovic K,Andersson C

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:A small number of previous studies have provided evidence that cocaine users (CU) exhibit impairments in complex social cognition tasks, while the more basic facial emotion recognition is widely unaffected. However, prosody and cross-modal emotion processing has not been systematically investigated in CU so ...

journal_title：Frontiers in psychiatry

authors： Hulka LM,Preller KH,Vonmoos M,Broicher SD,Quednow BB

更新日期：2013-09-05 00:00:00

abstract：:Sleep is a quiescent behavioral state during which complex homeostatic functions essential to health and well-being occur. Insomnia is a very common psychiatric disorder leading to a myriad of detrimental effects including loss of concentration, memory, and performance as well as disease. Current pharmaceutical treatm...

journal_title：Frontiers in psychiatry

authors： Jerath R,Beveridge C,Barnes VA

更新日期：2019-01-29 00:00:00

abstract：:Background: The impact of the ongoing COVID-19 pandemic on vulnerable groups like patients suffering from substance use disorders is expected to be tremendous, and corresponding concerns were raised early on by many experts around the world. Psychosocial distress, financial insecurities and physiological problems asso...

journal_title：Frontiers in psychiatry

authors： Yazdi K,Fuchs-Leitner I,Rosenleitner J,Gerstgrasser NW

更新日期：2020-12-16 00:00:00

abstract：:Background: Cognitive impairments in bipolar disorder (BD) such as memory deficits are associated with poor functional outcomes and it has been suggested that the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism contributes to individual variability in memory function in BD. The current study investigate...

journal_title：Frontiers in psychiatry

authors： Hørlyck LD,Macoveanu J,Vinberg M,Kessing LV,Siebner HR,Miskowiak KW

更新日期：2019-12-06 00:00:00

abstract：:The use of smartphone apps for research and clinical care in mental health has become increasingly popular, especially within youth mental health. In particular, digital phenotyping, the monitoring of data streams from a smartphone to identify proxies for functional outcomes like steps, sleep, and sociability, is of i...

journal_title：Frontiers in psychiatry

authors： Wisniewski H,Henson P,Torous J

更新日期：2019-09-23 00:00:00

abstract：:Background: The human striatum is a heterogeneous structure involved in diverse functional domains that related to distinct striatum subregions. Striatal dysfunction was thought to be a fundamental element in schizophrenia. However, the connectivity pattern of striatum solely based on functional or structural characte...

journal_title：Frontiers in psychiatry

authors： Zhang B,Lin P,Wang X,Öngür D,Ji X,Situ W,Yao S,Wang X

更新日期：2019-10-18 00:00:00