Keep an eye out for myasthenia gravis patients with an eye out.

Abstract:

:Eye trauma and blindness are common in the United States, with an incidence of over 2 million cases/year and 25 million blind adults, respectively. However, literature is surprisingly scarce on the potential confounding effect of eye trauma or blindness on the diagnosis of myasthenia gravis (MG), an autoimmune neuromuscular disease in which fluctuating ocular symptoms are the most distinguishing feature. We present the case of a 75-year-old man with eye enucleation referred for electrodiagnostic evaluation of the right upper limb after an accidental fall. Neurological examination showed proximal muscle weakness, but MG was not initially considered because the patient lacked the classic ocular symptoms of MG. The delay in diagnosis resulted in worsening of systemic MG symptoms, although in other patients it may have precipitated MG crisis or possibly death. Greater awareness that eye trauma or blindness can prevent expression of ocular symptoms in neuromuscular disorders is needed to avoid morbidity associated with an erroneous or delayed diagnosis.

journal_name

Front Neurol

journal_title

Frontiers in neurology

authors

Leis AA,Moore AR

doi

10.3389/fneur.2014.00112

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

112

issn

1664-2295

journal_volume

5

pub_type

杂志文章
  • Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection.

    abstract::Aims: To investigate the relationship between clinical and imaging features of stroke patients with patent foramen ovale (PFO) and those with spontaneous intracranial artery dissection (SIAD). Materials and methods: We retrospectively examined both clinical and imaging results of 40 stroke patients with PFO and 29 wit...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2019.00418

    authors: Huang Y,Cheng Y,Shao B,Zhou X,Liang H,Zhuang J,Bi Y

    更新日期:2019-04-24 00:00:00

  • A Case-Controlled Pilot Study on Rhythmic Auditory Stimulation-Assisted Gait Training and Conventional Physiotherapy in Patients With Parkinson's Disease Submitted to Deep Brain Stimulation.

    abstract::Deep brain stimulation (DBS) is indicated when motor disturbances in patients with idiopathic Parkinson's disease (PD) are refractory to current treatment options and significantly impair quality of life. However, post-DBS rehabilitation is essential, with particular regard to gait. Rhythmic auditory stimulation (RAS)...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2020.00794

    authors: Naro A,Pignolo L,Sorbera C,Latella D,Billeri L,Manuli A,Portaro S,Bruschetta D,Calabrò RS

    更新日期:2020-08-04 00:00:00

  • Atherosclerosis Might Be Responsible for Branch Artery Disease: Evidence From White Matter Hyperintensity Burden in Acute Isolated Pontine Infarction.

    abstract::Objective: To investigate an MRI-based etiological classification for acute isolated pontine infarcts and to assess differences in vascular risk factors, clinical characteristics and WMH burden among the etiological subtypes. Methods: All participants from SMART cohort with DWI-proven acute isolated pontine infarcts (...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2018.00840

    authors: Zhou L,Yao M,Peng B,Zhu Y,Ni J,Cui L

    更新日期:2018-10-09 00:00:00

  • A Novel TTC19 Mutation in a Patient With Neurological, Psychological, and Gastrointestinal Impairment.

    abstract::Mitochondrial complex III deficiency nuclear type 2 is an autosomal-recessive disorder caused by mutations in TTC19 gene. TTC19 is involved in the preservation of mitochondrial complex III, which is responsible for transfer of electrons from reduced coenzyme Q to cytochrome C and thus, contributes to the formation of ...

    journal_title:Frontiers in neurology

    pub_type:

    doi:10.3389/fneur.2019.00944

    authors: Habibzadeh P,Inaloo S,Silawi M,Dastsooz H,Farazi Fard MA,Sadeghipour F,Faghihi Z,Rezaeian M,Yavarian M,Böhm J,Faghihi MA

    更新日期:2019-09-04 00:00:00

  • CADASIL vs. Multiple Sclerosis: Is It Misdiagnosis or Concomitant? A Case Series.

    abstract::Introduction: Cerebral autosomal dominant arteriopathy and subcortical infarct leukoencephalopathy (CADASIL) is the most common form of hereditary stroke caused by a mutation in the NOTCH3 gene located on the short arm of chromosome 19. A small number of published reports describe CADASIL patients who were initially d...

    journal_title:Frontiers in neurology

    pub_type:

    doi:10.3389/fneur.2020.00860

    authors: Khan A,Abedi V,Li J,Malik MT,Esch M,Zand R

    更新日期:2020-09-04 00:00:00

  • Extracranial Trigger Site Surgery for Migraine: A Systematic Review With Meta-Analysis on Elimination of Headache Symptoms.

    abstract::Introduction: The headache phase of migraine could in selected cases potentially be treated by surgical decompression of one or more "trigger sites," located at frontal, temporal, nasal, and occipital sites. This systematic review with subsequent meta-analysis aims at critically evaluating the currently available evid...

    journal_title:Frontiers in neurology

    pub_type:

    doi:10.3389/fneur.2019.00089

    authors: Vincent AJPE,van Hoogstraten WS,Maassen Van Den Brink A,van Rosmalen J,Bouwen BLJ

    更新日期:2019-02-14 00:00:00

  • The Role of Decompressive Craniectomy in the Context of Severe Traumatic Brain Injury: Summary of Results and Analysis of the Confidence Level of Conclusions From Systematic Reviews and Meta-Analyses.

    abstract::Introduction: Traumatic brain injury (TBI) is a global epidemic. The incidence of TBI in low and middle-income countries (LMICs) is three times greater than in high-income countries (HICs). Decompressive craniectomy (DC) is a surgical procedure to reduce intracranial pressure (ICP) and prevent secondary injury. Multip...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审

    doi:10.3389/fneur.2019.01063

    authors: Rubiano AM,Carney N,Khan AA,Ammirati M

    更新日期:2019-10-10 00:00:00

  • A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation.

    abstract::Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities. ADPKD is caused by mutations in either PKD1 or PKD2 genes that encode for integral membrane proteins Polycystin-1 (PC1) and Polycystin-2 (PC2), respectively. Ex...

    journal_title:Frontiers in neurology

    pub_type:

    doi:10.3389/fneur.2018.00383

    authors: Thomas C,Zühlsdorf A,Hörtnagel K,Mulahasanovic L,Grauer OM,Kümpers P,Wiendl H,Meuth SG

    更新日期:2018-05-25 00:00:00

  • Cognitive gains from gist reasoning training in adolescents with chronic-stage traumatic brain injury.

    abstract::Adolescents with traumatic brain injury (TBI) typically demonstrate good recovery of previously acquired skills. However, higher-order and later emergent cognitive functions are often impaired and linked to poor outcomes in academic and social/behavioral domains. Few control trials exist that test cognitive treatment ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2014.00087

    authors: Cook LG,Chapman SB,Elliott AC,Evenson NN,Vinton K

    更新日期:2014-06-11 00:00:00

  • Excessive Daytime Sleepiness in Tension-Type Headache: A Population Study.

    abstract::Excessive daytime sleepiness (EDS) is a prevalent sleep-related complaint across the general population and has been reported to be associated with headache. Tension-type headache (TTH) is the most commonly encountered headache and accounts for a significant amount of disease burden. However, the association between E...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2019.01282

    authors: Kim KM,Kim J,Cho SJ,Kim WJ,Yang KI,Yun CH,Chu MK

    更新日期:2019-12-03 00:00:00

  • Prolonged Static Whole-Body Roll-Tilt and Optokinetic Stimulation Significantly Bias the Subjective Postural Vertical in Healthy Human Subjects.

    abstract::Background: Prolonged static whole-body roll-tilt has been shown to bias estimates of the direction of gravity when assessed by static paradigms such as the subjective visual vertical and the subjective haptic vertical. Objective: We hypothesized that these shifts are paradigm-independent and thus predicted a post-til...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2020.595975

    authors: Wedtgrube A,Bockisch CJ,Straumann D,Tarnutzer AA

    更新日期:2020-10-15 00:00:00

  • Erratum: Standards in Pupillography.

    abstract::[This corrects the article DOI: 10.3389/fneur.2019.00129.]. ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,已发布勘误

    doi:10.3389/fneur.2019.00371

    authors: Frontiers Production Office.

    更新日期:2019-03-27 00:00:00

  • Altered Insular and Occipital Responses to Simulated Vertical Self-Motion in Patients with Persistent Postural-Perceptual Dizziness.

    abstract:BACKGROUND:Persistent postural-perceptual dizziness (PPPD) is a common functional vestibular disorder characterized by persistent symptoms of non-vertiginous dizziness and unsteadiness that are exacerbated by upright posture, self-motion, and exposure to complex or moving visual stimuli. Recent physiologic and neuroima...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2017.00529

    authors: Riccelli R,Passamonti L,Toschi N,Nigro S,Chiarella G,Petrolo C,Lacquaniti F,Staab JP,Indovina I

    更新日期:2017-10-17 00:00:00

  • Aging Increases Compensatory Saccade Amplitude in the Video Head Impulse Test.

    abstract:OBJECTIVE:Rotational vestibular function declines with age resulting in saccades as a compensatory mechanism to improve impaired gaze stability. Small reductions in rotational vestibulo-ocular reflex (VOR) gain that would be considered clinically normal have been associated with compensatory saccades. We evaluated whet...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2016.00113

    authors: Anson ER,Bigelow RT,Carey JP,Xue QL,Studenski S,Schubert MC,Weber KP,Agrawal Y

    更新日期:2016-07-18 00:00:00

  • Comparison of visual evoked potentials and retinal nerve fiber layer thickness in Alzheimer's disease.

    abstract:INTRODUCTION:Alzheimer's disease (AD) is a long term progressive neurodegenerative disease and might affect the retinal nerve fiber layer thickness (RNFLT) of the eye. There is increasing evidence that visual evoked potentials (VEP), which are an objective way to indicate visual field loss, might be affected by the dis...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2013.00203

    authors: Kromer R,Serbecic N,Hausner L,Froelich L,Beutelspacher SC

    更新日期:2013-12-16 00:00:00

  • Impact of Incident Parkinson's Disease on Satisfaction With Life.

    abstract::Aim: The aim of the study was to investigate the effect of the onset of Parkinson's disease (PD) on life satisfaction. Method: Data from 2008, 2011, and 2014 were used from a population-based prospective cohort (German Ageing Survey; 8,982 observations in FE regression analysis) of community-residing individuals in th...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2018.00589

    authors: Buczak-Stec EW,König HH,Hajek A

    更新日期:2018-07-25 00:00:00

  • The Role of Palliative Care in Chronic Progressive Neurological Diseases-A Survey Amongst Neurologists in the Netherlands.

    abstract::Background: Chronic progressive neurological diseases like high grade glioma (HGG), Parkinson's disease (PD), and multiple sclerosis (MS) are incurable, and associated with increasing disability including cognitive impairment, and reduced life expectancy. Patients with these diseases have complex care needs. Therefore...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2018.01157

    authors: Walter HAW,Seeber AA,Willems DL,de Visser M

    更新日期:2019-01-14 00:00:00

  • Eye Movements in Parkinson's Disease and Inherited Parkinsonian Syndromes.

    abstract::Despite extensive research, the functions of the basal ganglia (BG) in movement control have not been fully understood. Eye movements, particularly saccades, are convenient indicators of BG function. Here, we review the main oculomotor findings reported in Parkinson's disease (PD) and genetic parkinsonian syndromes. P...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审

    doi:10.3389/fneur.2017.00592

    authors: Pretegiani E,Optican LM

    更新日期:2017-11-09 00:00:00

  • Poststroke Depression Biomarkers: A Narrative Review.

    abstract::Poststroke depression (PSD) is the most prevalent psychiatric disorder after stroke, which is independently correlated with negative clinical outcome. The identification of specific biomarkers could help to increase the sensitivity of PSD diagnosis and elucidate its pathophysiological mechanisms. The aim of current st...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审

    doi:10.3389/fneur.2018.00577

    authors: Levada OA,Troyan AS

    更新日期:2018-07-16 00:00:00

  • Novel Phenotypes and Cardiac Involvement Associated With DNA2 Genetic Variants.

    abstract::Objectives: To report two novel DNA2 gene mutations causing early onset myopathy with cardiac involvement and late onset mitochondriopathy with rhabdomyolysis. Methods: We performed detailed clinical, muscle histopathology and molecular studies including mitochondrial gene NGS analysis in two patients (Patient 1 and 2...

    journal_title:Frontiers in neurology

    pub_type:

    doi:10.3389/fneur.2019.01049

    authors: González-Del Angel A,Bisciglia M,Vargas-Cañas S,Fernandez-Valverde F,Kazakova E,Escobar RE,Romero NB,Jardel C,Rucheton B,Stojkovic T,Malfatti E

    更新日期:2019-10-04 00:00:00

  • A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report.

    abstract::We describe the case of one patient with pure sporadic hemiplegic migraine (SHM) with a novel ATP1A2 gene variant and a large patent foramen ovale (PFO) with atrial septal aneurysm. In hemiplegic migraine (HM), the relationship between incomplete penetrance, environmental triggers, and phenotypic expression is underde...

    journal_title:Frontiers in neurology

    pub_type:

    doi:10.3389/fneur.2018.00332

    authors: Perrotta A,Gambardella S,Ambrosini A,Anastasio MG,Albano V,Fornai F,Pierelli F

    更新日期:2018-05-17 00:00:00

  • Developmental dynamics of radial vulnerability in the cerebral compartments in preterm infants and neonates.

    abstract::The developmental vulnerability of different classes of axonal pathways in preterm white matter is not known. We propose that laminar compartments of the developing cerebral wall serve as spatial framework for axonal growth and evaluate potential of anatomical landmarks for understanding reorganization of the cerebral...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2014.00139

    authors: Kostović I,Kostović-Srzentić M,Benjak V,Jovanov-Milošević N,Radoš M

    更新日期:2014-07-29 00:00:00

  • Electroencephalography Network Effects of Corpus Callosotomy in Patients with Lennox-Gastaut Syndrome.

    abstract:OBJECTIVES:This study aimed to investigate the functional network effects of corpus callosotomy (CC), a well-recognized palliative surgical therapy for patients with Lennox-Gastaut syndrome (LGS). Specifically, we sought to gain insight into the effects of CC on LGS remission, based on brain networks in LGS by calculat...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2017.00456

    authors: Liang JG,Lee D,Youn SE,Kim HD,Kim NY

    更新日期:2017-09-04 00:00:00

  • Comparing Single vs. Combined Cerebrospinal Fluid Parameters for Diagnosing Full-Term Neonatal Bacterial Meningitis.

    abstract::Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2019.00012

    authors: Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

    更新日期:2019-01-23 00:00:00

  • Assessing the Safety of Craniotomy for Resection of Primary Central Nervous System Lymphoma: A Nationwide Inpatient Sample Analysis.

    abstract:BACKGROUND:Unlike many other central nervous system (CNS) tumors, the surgical management of primary central nervous system lymphomas (PCNSL) is traditionally limited by diagnostic biopsy. Studies that predate the use of modern neurosurgical techniques have reported a prohibitive operative morbidity for this surgery. T...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2017.00478

    authors: Yun J,Yang J,Cloney M,Mehta A,Singh S,Iwamoto FM,Neugut AI,Sonabend AM

    更新日期:2017-09-12 00:00:00

  • Epilepsy and Its Interaction With Sleep and Circadian Rhythm.

    abstract::Growing evidence shows the bidirectional interactions between sleep, circadian rhythm, and epilepsy. Comprehending how these interact with each other may help to advance our understanding of the pathophysiology of epilepsy and develop new treatment strategies to improve seizure control by reducing the medication side ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审

    doi:10.3389/fneur.2020.00327

    authors: Jin B,Aung T,Geng Y,Wang S

    更新日期:2020-05-08 00:00:00

  • Corrigendum: Sleep Disorders in Leucine-Rich Glioma-Inactivated Protein 1 and Contactin Protein-Like 2 Antibody-Associated Diseases.

    abstract::[This corrects the article DOI: 10.3389/fneur.2020.00696.]. ...

    journal_title:Frontiers in neurology

    pub_type: 已发布勘误

    doi:10.3389/fneur.2020.607331

    authors: Lin N,Hao H,Guan H,Sun H,Liu Q,Lu Q,Jin L,Ren H,Huang Y

    更新日期:2020-10-30 00:00:00

  • Perturbation-Based Balance Training to Improve Step Quality in the Chronic Phase After Stroke: A Proof-of-Concept Study.

    abstract::Introduction: People with stroke often have impaired stepping responses following balance perturbations, which increases their risk of falling. Computer-controlled movable platforms are promising tools for delivering perturbation-based balance training under safe and standardized circumstances. Purpose: This proof-of-...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2018.00980

    authors: van Duijnhoven HJR,Roelofs JMB,den Boer JJ,Lem FC,Hofman R,van Bon GEA,Geurts ACH,Weerdesteyn V

    更新日期:2018-11-22 00:00:00

  • Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's Disease.

    abstract::Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central nervous system due to molecules released from brain-resident and/or blood-derived immune cells. Furt...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审

    doi:10.3389/fneur.2018.00860

    authors: Troncoso-Escudero P,Parra A,Nassif M,Vidal RL

    更新日期:2018-10-15 00:00:00

  • Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers.

    abstract:INTRODUCTION:Core cerebrospinal fluid (CSF) biomarkers - Aβ42, Tau, and phosphorylated Tau (pTau) - have been recently incorporated in the revised criteria for Alzheimer's disease (AD). However, their widespread clinical application lacks standardization. Pre-analytical sample handling and storage play an important rol...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章

    doi:10.3389/fneur.2015.00153

    authors: Leitão MJ,Baldeiras I,Herukka SK,Pikkarainen M,Leinonen V,Simonsen AH,Perret-Liaudet A,Fourier A,Quadrio I,Veiga PM,de Oliveira CR

    更新日期:2015-07-08 00:00:00