Consumer Demand for Online Dizziness Information: If You Build it, They may Come.

abstract：OBJECT:Aneurysmal subarachnoid hemorrhage (aSAH) is a common cause of death or long-term disability. Despite advances in neurocritical care, there is still only a very limited ability to monitor the development of secondary brain injury or to predict neurological outcome after aSAH. Soluble urokinase-type plasminogen a...

journal_title：Frontiers in neurology

authors： Kiiski H,Jalkanen V,Ala-Peijari M,Hämäläinen M,Moilanen E,Peltola J,Tenhunen J

更新日期：2017-04-18 00:00:00

abstract：:Resting state functional MRI (rs-fMRI) has provided important insights into functional reorganization in subjects with Multiple Sclerosis (MS) at different stage of disease. In this cross-sectional study we first assessed, by means of rs-fMRI, the impact of overall T2 lesion load (T2LL) and MS severity score (MSSS) on...

journal_title：Frontiers in neurology

authors： Castellazzi G,Debernard L,Melzer TR,Dalrymple-Alford JC,D'Angelo E,Miller DH,Gandini Wheeler-Kingshott CAM,Mason DF

更新日期：2018-08-20 00:00:00

abstract：:Anticoagulation is highly effective in preventing stroke due to atrial fibrillation, but numerous studies have demonstrated low utilization of anticoagulation for these patients. Assessment of clinicians' attitudes on this topic indicate that fear of intracerebral hemorrhage (ICH), rather than appreciation of anticoag...

journal_title：Frontiers in neurology

authors： Fisher M

更新日期：2013-10-04 00:00:00

abstract：OBJECTIVE:Tinnitus is a common symptom of hearing impairment. Patients who are bilaterally hard of hearing are often affected by tinnitus. However, they cannot undergo any of the standard tinnitus therapies, since they rely on hearing. Cochlear implantation (CI) used to treat severe hearing disabilities, such as bilate...

journal_title：Frontiers in neurology

authors： Knopke S,Szczepek AJ,Häussler SM,Gräbel S,Olze H

更新日期：2017-04-25 00:00:00

abstract：:Exposure of the brain to brief, non-harmful seizures can activate protective mechanisms that temporarily generate a damage-refractory state. This process, termed epileptic tolerance, is associated with large-scale down-regulation of gene expression. Polycomb group (PcG) proteins are master controllers of gene silencin...

journal_title：Frontiers in neurology

authors： Reynolds JP,Miller-Delaney SF,Jimenez-Mateos EM,Sano T,McKiernan RC,Simon RP,Henshall DC

更新日期：2015-03-10 00:00:00

abstract：:Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic transformation. While significant advances have been made over the past two decades with regard to emergent treatment of AIS, many of the therapeutic options are limited by an increased risk of hemorrhage. Here, we sought to review...

journal_title：Frontiers in neurology

authors： Sussman ES,Connolly ES Jr

更新日期：2013-06-10 00:00:00

abstract：:Lifestyle factors such as intellectual stimulation, cognitive and social engagement, nutrition, and various types of exercise appear to reduce the risk for common age-associated disorders such as Alzheimer's disease (AD) and vascular dementia. In fact, many studies have suggested that promoting physical activity can h...

journal_title：Frontiers in neurology

authors： Foster PP,Rosenblatt KP,Kuljiš RO

更新日期：2011-05-06 00:00:00

abstract：:A carotid-jugular fistula is a direct communication between the carotid artery and the jugular vein. Both congenital and spontaneous internal carotid-jugular fistulas are extremely rare. We describe the first case of successful endovascular treatment for a congenital internal carotid-jugular fistula. We report a 64-ye...

journal_title：Frontiers in neurology

authors： Wang M,Fan W,Mungur R,Gu J,Wan S

更新日期：2018-12-18 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked recessive neuromuscular disorders caused by mutations in DMD. A high-quality database of DMD/BMD is essential not only for clinical practice but also for fundamental research. Here, we aimed to build the largest Chinese national dystrop...

journal_title：Frontiers in neurology

authors： Tong YR,Geng C,Guan YZ,Zhao YH,Ren HT,Yao FX,Ling C,Wang DC,Chen L,Cui LY,Zhang SY,Dai Y

更新日期：2020-09-30 00:00:00

abstract：:Parkinson's disease (PD) is not a single entity but rather a heterogeneous neurodegenerative disorder. The present study aims to conduct a critical systematic review of the literature to describe the main pharmacological strategies to treat cognitive dysfunction and major depressive disorder in PD patients. We perform...

journal_title：Frontiers in neurology

authors： Sandoval-Rincón M,Sáenz-Farret M,Miguel-Puga A,Micheli F,Arias-Carrión O

更新日期：2015-03-31 00:00:00

abstract：:Autism Spectrum Disorders comprise conditions that may affect cognitive development, motor skills, social interaction, communication, and behavior. This set of functional deficits often results in lack of independence for the diagnosed individuals, and severe distress for patients, families, and caregivers. There is a...

journal_title：Frontiers in neurology

authors： Fleury-Teixeira P,Caixeta FV,Ramires da Silva LC,Brasil-Neto JP,Malcher-Lopes R

更新日期：2019-10-31 00:00:00

abstract：INTRODUCTION:We sought to determine whether compliance with scheduled nimodipine in subarachnoid hemorrhage patients impacted patient outcomes, with the intent of guiding future nimodipine management in patients who experience nimodipine-induced hypotension. METHODS:We performed a retrospective analysis of 118 consecu...

journal_title：Frontiers in neurology

authors： Wessell A,Kole MJ,Badjatia N,Parikh G,Albrecht JS,Schreibman DL,Simard JM

更新日期：2017-06-09 00:00:00

abstract：:Background: Neurofilament light chain (NFL) was believed to be a promising biomarker for the diagnosis of Amyotrophic lateral sclerosis (ALS) and disease burden evaluation. Objective: To determine the serum NFL level and its clinical relevance, including its association with disease severity [evaluated by the ALS Func...

journal_title：Frontiers in neurology

authors： Sugimoto K,Han Y,Song Y,Gao Y

更新日期：2020-12-03 00:00:00

abstract：:We previously identified a distinct mutation pattern in the antibody genes of B cells isolated from cerebrospinal fluid (CSF) that can identify patients who have relapsing-remitting multiple sclerosis (RRMS) and patients with clinically isolated syndromes who will convert to RRMS. This antibody gene signature (AGS) wa...

journal_title：Frontiers in neurology

authors： Rounds WH,Ligocki AJ,Levin MK,Greenberg BM,Bigwood DW,Eastman EM,Cowell LG,Monson NL

更新日期：2014-09-16 00:00:00

abstract：:Objective: To investigate the dynamic amplitude of low-frequency fluctuations (dALFFs) in patients with Parkinson's disease (PD) and healthy controls (HCs) and further explore whether dALFF can be used to test the feasibility of differentiating PD from HCs. Methods: Twenty-eight patients with PD and 28 demographically...

journal_title：Frontiers in neurology

authors： Zhang C,Dou B,Wang J,Xu K,Zhang H,Sami MU,Hu C,Rong Y,Xiao Q,Chen N,Li K

更新日期：2019-10-01 00:00:00

abstract：:Sleep disturbances such as excessive daytime sleepiness, central and obstructive sleep apneas, restless legs syndrome, and rapid eye movement sleep dysregulation are prominent in patients with myotonic dystrophy type 1 (DM1). Mild intellectual deficits presented in many patients with DM1. In addition, psychosocial iss...

journal_title：Frontiers in neurology

authors： Urata Y,Nakamura M,Shiokawa N,Yasuniwa A,Takamori N,Imamura K,Hayashi T,Ishizuka T,Kasugai M,Sano A

更新日期：2020-02-14 00:00:00

abstract：:Objective: Hemorrhagic transformation (HT) in ischemic moyamoya disease (MMD), reasonably defined as hemorrhage events in patients with ischemic onset manifestation, leads to a poor outcome. This study aims to reveal factors associated with HT in patients with ischemic onset manifestation and to assess the outcome of ...

journal_title：Frontiers in neurology

authors： Lu J,Li Z,Zhao Y,Chen X,Shi G,Zhao J

更新日期：2020-06-25 00:00:00

abstract：:Traumatic brain injury (TBI) can cause seizures and the development of epilepsy. The incidence of seizures varies from 21% in patients with severe brain injuries to 50% in patients with war-related penetrating TBI. In the acute and sub-acute periods following injury, seizures can lead to increased intracranial pressur...

journal_title：Frontiers in neurology

authors： Kirmani BF,Mungall D,Ling G

更新日期：2013-11-01 00:00:00

abstract：:Background: The causal relationship between serum lipid levels and the risk of Parkinson's disease (PD) remains largely uncertain. We summarized the existing controversial evidence on this topic. Methods: We searched the electronic databases for observational studies from January 1988 to March 2020. We applied random-...

journal_title：Frontiers in neurology

authors： Jiang Z,Xu X,Gu X,Ou R,Luo X,Shang H,Song W

更新日期：2020-06-26 00:00:00

abstract：:Hearing and balance impairment are the most frequently reported features of infratentorial (classical) superficial siderosis (iSS). There are few comprehensive descriptions of audiovestibular function in iSS and therefore limited understanding of the affected segment(s) of the audiovestibular pathway. In addition, mon...

journal_title：Frontiers in neurology

authors： Kharytaniuk N,Cowley P,Werring DJ,Bamiou DE

更新日期：2021-01-14 00:00:00

abstract：:Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central nervous system due to molecules released from brain-resident and/or blood-derived immune cells. Furt...

journal_title：Frontiers in neurology

authors： Troncoso-Escudero P,Parra A,Nassif M,Vidal RL

更新日期：2018-10-15 00:00:00

abstract：:Autoimmune inflammation of the limbic gray matter structures of the human brain has recently been identified as major cause of mesial temporal lobe epilepsy with interictal temporal epileptiform activity and slowing of the electroencephalogram, progressive memory disturbances, as well as a variety of other behavioral,...

journal_title：Frontiers in neurology

authors： Ehling P,Melzer N,Budde T,Meuth SG

更新日期：2015-07-15 00:00:00

abstract：:Migraine is a chronic disease characterized by unilateral, pulsating, and often moderate-to-severe recurrent episodes of headache with nausea and vomiting. It affects approximately 15% of the general population, yet the underlying pathophysiological mechanisms are not fully understood. Optical coherence tomography (OC...

journal_title：Frontiers in neurology

authors： Ascaso FJ,Marco S,Mateo J,Martínez M,Esteban O,Grzybowski A

更新日期：2017-12-13 00:00:00

abstract：:Objectives: Elevated neurofilament light chain (NFL) levels within the cerebrospinal fluid (CSF) are a biomarker representing axonal neurodegeneration in rapid progressive neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). It is unclear to what extent the levels of NFL increase in the CSF (CSF-NFL...

journal_title：Frontiers in neurology

authors： Pawlitzki M,Schreiber S,Bittner D,Kreipe J,Leypoldt F,Rupprecht K,Carare RO,Meuth SG,Vielhaber S,Körtvélyessy P

更新日期：2018-12-14 00:00:00

abstract：OBJECTIVES:Stroke can happen to people away from home. It is unknown whether non-resident and resident stroke patients have equal access to thrombolysis. MATERIALS AND METHODS:Consecutive patients cared for by the Stroke Emergency Mobile between 2011 and 2016 after prompting suspicion of acute stroke during the emerge...

journal_title：Frontiers in neurology

authors： Schlemm L,Turc G,Audebert HJ,Ebinger M

更新日期：2017-06-30 00:00:00

abstract：:This study reports the case of an acoustic shock injury (ASI), which did not result in a significant hearing loss, but was followed by manifold chronic symptoms both within (tinnitus, otalgia, tingling in the ear, tension in the ear, and red tympanum) and outside the ears (blocked nose, pain in the neck/temporal regio...

journal_title：Frontiers in neurology

authors： Londero A,Charpentier N,Ponsot D,Fournier P,Pezard L,Noreña AJ

更新日期：2017-08-16 00:00:00

abstract：:SARS-CoV-2 is a highly pathogenic coronavirus that has caused an ongoing worldwide pandemic. Emerging in Wuhan, China in December 2019, the virus has spread rapidly around the world. Corona virus disease 2019 (COVID-19), which is caused by SARS-CoV-2, has resulted in significant morbidity and mortality. The most promi...

journal_title：Frontiers in neurology

authors： Khateb M,Bosak N,Muqary M

更新日期：2020-06-23 00:00:00

abstract：:Background: Patients with traumatic brain injury (TBI) exhibit a variable and unpredictable outcome. The proteins interleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have shown predictive values for the presence of intracranial lesions. Aim: To evaluate the individual and combined outcome prediction a...

journal_title：Frontiers in neurology

authors： Lagerstedt L,Azurmendi L,Tenovuo O,Katila AJ,Takala RSK,Blennow K,Newcombe VFJ,Maanpää HR,Tallus J,Hossain I,van Gils M,Menon DK,Hutchinson PJ,Zetterberg H,Posti JP,Sanchez JC

更新日期：2020-06-02 00:00:00

abstract：OBJECTIVE:Morphological changes of recent small subcortical infarcts are not well defined. The purpose of the present study was to describe the MRI characteristics of the evolution for this stroke subtype. METHODS:We conducted a retrospective review of patients diagnosed with definite supratentorial recent small subco...

journal_title：Frontiers in neurology

authors： Okazaki S,Hornberger E,Griebe M,Gass A,Hennerici MG,Szabo K

更新日期：2015-05-26 00:00:00

abstract：:Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are major contributors to morbidity and mortality. Following the initial insult, patients may deteriorate due to secondary brain damage. The underlying molecular and cellular cascades incorporate components of the innate immune system. There are different ...

journal_title：Frontiers in neurology

authors： Thelin EP,Tajsic T,Zeiler FA,Menon DK,Hutchinson PJA,Carpenter KLH,Morganti-Kossmann MC,Helmy A

更新日期：2017-07-20 00:00:00