Smoking cessation in lung cancer-achievable and effective.

abstract：INTRODUCTION:Many psychotropic drugs can delay cardiac repolarization and thereby prolong the rate-corrected QT interval (QTc). A prolonged QTc often arouses concern in clinical practice, as it can be followed, in rare cases, by the life-threatening polymorphic ventricular tachyarrhythmia called torsade de pointes (TdP...

journal_title：Deutsches Arzteblatt international

authors： Wenzel-Seifert K,Wittmann M,Haen E

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The treatment options for bcr-abl positive chronic myelogenous leukemia (CML) include chemotherapy, immune therapy, allogeneic stem cell transplantation, and molecular therapy. The tyrosine kinase inhibitor imatinib was approved for the treatment of CML in 2002. Data from clinical trials allow a comparison o...

journal_title：Deutsches Arzteblatt international

authors： von Bubnoff N,Duyster J

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:A confusing variety of options are available for the treatment of depressive disorders. METHOD:Selective literature review under consideration of current guidelines. RESULTS:The treatment of depression can be divided into acute, maintenance and prophylactic phases. The basic forms of treatment are pharma...

journal_title：Deutsches Arzteblatt international

authors： Bschor T,Adli M

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Magnetic resonance tomography (MRT) is the investigation of choice for diagnosing cerebral glioma, but its capacity to differentiate tumor tissue from non-specific tissue changes is limited. Positron emission tomography (PET) and single photon emission computerized tomography (SPECT) using radiolabeled ami...

journal_title：Deutsches Arzteblatt international

authors： Langen KJ,Tatsch K,Grosu AL,Jacobs AH,Weckesser M,Sabri O

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Surgical site infections (SSI) are among the most common healthcare- associated infections. The aim of our explorative study was to determine how selected climatic factors are associated with SSI rates. METHODS:SSI rates were calculated for operative procedures included in the surgi- cal site infection surv...

journal_title：Deutsches Arzteblatt international

authors： Aghdassi SJS,Schwab F,Hoffmann P,Gastmeier P

更新日期：2019-08-05 00:00:00

abstract：BACKGROUND:Direct (non-vitamin-K-dependent) oral anticoagulants (DOAC) are given as an alternative to vitamin K antagonists (VKA) to prevent stroke and embolic disease in patients with atrial fibrillation that is not due to pathology of the heart valves. Fatal hemorrhage is rarer when DOACs are given (nonvalvular atria...

journal_title：Deutsches Arzteblatt international

authors： Maegele M,Grottke O,Schöchl H,Sakowitz OA,Spannagl M,Koscielny J

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Despite sparse documentation of their long-term therapeutic effects and side effects, antipsychotic drugs have come to be prescribed more frequently for children and adolescents in recent years, both in the USA and in Europe. No current data are available about antipsychotic prescriptions for this age group ...

journal_title：Deutsches Arzteblatt international

authors： Bachmann CJ,Lempp T,Glaeske G,Hoffmann F

更新日期：2014-01-17 00:00:00

abstract：BACKGROUND:High-altitude travel, for mountain climbing, trekking, or sightseeing, has become very popular. Therefore, the awareness of its dangers has increased, and many prospective travelers seek medical advice before setting forth on their trip. METHODS:We selectively searched the literature for relevant original a...

journal_title：Deutsches Arzteblatt international

authors： Schommer K,Bärtsch P

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Lung transplantation is the final treatment option in the end stage of certain lung diseases, once all possible conservative treatments have been exhausted. Depending on the indication for which lung transplantation is performed, it can improve the patient's quality of life (e.g., in emphysema) and/ or prolo...

journal_title：Deutsches Arzteblatt international

authors： Hartert M,Senbaklavacin O,Gohrbandt B,Fischer BM,Buhl R,Vahld CF

更新日期：2014-02-14 00:00:00

abstract：BACKGROUND:The treatment of Hodgkin's disease (HD; also called Hodgkin's lymphoma) in children and adolescents with radiotherapy and chemotherapy leads to high survival rates but has a number of late effects. The most serious one is the development of a secondary malignant tumor, usually in the field that was irradiate...

journal_title：Deutsches Arzteblatt international

authors： Schellong G,Riepenhausen M,Ehlert K,Brämswig J,Dörffel W,German Working Group on the Long-Term Sequelae of Hodgkin's Disease.,Schmutzler RK,Rhiem K,Bick U,German Consortium for Hereditary Breast and Ovarian Cancer.

更新日期：2014-01-06 00:00:00

abstract：BACKGROUND:Inflammatory bowel diseases are common in Europe, with prevalences as high as 1 in 198 persons (ulcerative colitis) and 1 in 310 persons (Crohn's disease). METHODS:This review is based on pertinent articles retrieved by a search in PubMed and in German and European guidelines and Cochrane reviews of control...

journal_title：Deutsches Arzteblatt international

authors： Wehkamp J,Götz M,Herrlinger K,Steurer W,Stange EF

更新日期：2016-02-05 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous system. There are at least 150 000 persons with MS in Germany. Recent years have seen the approval of new drugs against. METHODS:This article is based on pertinent literature retrieved by a selective search in PubMed as wel...

journal_title：Deutsches Arzteblatt international

authors： Havla J,Warnke C,Derfuss T,Kappos L,Hartung HP,Hohlfeld R

更新日期：2016-12-26 00:00:00

abstract：BACKGROUND:The conservative treatment of traumatic thoracolumbar vertebral fractures is often not clearly defined. METHODS:This review is based on articles retrieved by a systematic search in the PubMed and Web of Science databases for publications up to February 2018 dealing with the conservative treatment of traumat...

journal_title：Deutsches Arzteblatt international

authors： Spiegl UJ,Fischer K,Schmidt J,Schnoor J,Delank S,Josten C,Schulte T,Heyde CE

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Few reliable data are available on the epidemiology and treatment of spontaneous pneumothorax. We studied the sex and age distribution, frequency of hospitalization, mortality, and conservative versus surgical care of this condition in Germany in order to draw well-founded conclusions about its in-hospital d...

journal_title：Deutsches Arzteblatt international

authors： Schnell J,Koryllos A,Lopez-Pastorini A,Lefering R,Stoelben E

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:Atrial fibrillation is the most common type of cardiac arrhythmia and is associated with elevated rates of stroke, heart failure, hospital admission, and death. Its prevalence in the overall population is 1.5% to 2%. To convert atrial fibrillation to sinus rhythm, cardioversion is needed. METHODS:This revie...

journal_title：Deutsches Arzteblatt international

authors： Klein HH,Trappe HJ

更新日期：2015-12-11 00:00:00

abstract：BACKGROUND:Dermatologists, paediatricians, and general practitioners are often consulted by worried parents for the evaluation of a cutaneous tumor. METHODS:Selective literature review. RESULTS:Only 1-2% of skin tumors excised in children turn out to be malignant when examined histologically. Warning signs of maligna...

journal_title：Deutsches Arzteblatt international

authors： Hamm H,Höger PH

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The German Standing Committee on Vaccination (STIKO) recommends vaccination against human papillomaviruses (HPV) of the high-risk types 16 and 18. The duration of protection afforded by HPV vaccines has been reported in multiple studies to date but has not been systematically evaluated. METHOD:Systematic li...

journal_title：Deutsches Arzteblatt international

authors： Deleré Y,Wichmann O,Klug SJ,van der Sande M,Terhardt M,Zepp F,Harder T

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:In endocrine orbitopathy (EO), disfiguring proptosis and diplopia impair patients' quality of life both at home and at work. METHODS:From late 2006 to the beginning of 2008, 250 outpatients in an interdisciplinary thyroid and eye clinic filled out a questionnaire about their quality of life, occupational di...

journal_title：Deutsches Arzteblatt international

authors： Ponto KA,Pitz S,Pfeiffer N,Hommel G,Weber MM,Kahaly GJ

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:About 17% of all children suffer from a mental disorder in early childhood, defined as the period up to the age of 6 years. METHODS:This review is based on publications retrieved by a selective search in PubMed and the Web of Science, as well as on the authors' clinical and scientific experience. RESULTS:I...

journal_title：Deutsches Arzteblatt international

authors： von Klitzing K,Döhnert M,Kroll M,Grube M

更新日期：2015-05-25 00:00:00

abstract：BACKGROUND:Cluster-randomized trials (CRT) are needed to compare interventions that are allocated to entire groups of subjects, rather than to individuals. Publications about CRT have become steadily more common over the past decade. Readers of such publications should be able to categorize and interpret the findings o...

journal_title：Deutsches Arzteblatt international

authors： Lorenz E,Köpke S,Pfaff H,Blettner M

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:Infections with multidrug-resistant gram-negative bacteria are hard to treat and cause high morbidity and mortality. The direct transmission of such pathogens is well documented, and measures to protect other patients would seem indicated. Nonetheless, evidence-based recommendations are not yet available bec...

journal_title：Deutsches Arzteblatt international

authors： Mattner F,Bange FC,Meyer E,Seifert H,Wichelhaus TA,Chaberny IF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Age-related macular degeneration (AMD) is a common retinal disease in older people. In Europe, about 1.6% of persons over age 65 and more than 13% of persons over age 85 have late-stage AMD, which can severely impair vision. The development of AMD is influenced both by environmental factors and by a strong h...

journal_title：Deutsches Arzteblatt international

authors： Weber BH,Charbel Issa P,Pauly D,Herrmann P,Grassmann F,Holz FG

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:With improved cure rates of cancer in children and adolescents, the long-term effects of oncological treatment, including impaired fertility, have become an important clinical issue. METHODS:In 2008, we conducted a nationwide survey in Germany in which we asked 4689 female and male patients who had been tre...

journal_title：Deutsches Arzteblatt international

authors： Balcerek M,Reinmuth S,Hohmann C,Keil T,Borgmann-Staudt A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Overweight and obesity are generally thought to elevate morbidity and mortality. New data call this supposed association into question. METHODS:The Cochrane, Pubmed, and other databases were systematically searched for a combination of relevant terms and subject headings. Meta-analyses and cohort studies ba...

journal_title：Deutsches Arzteblatt international

authors： Lenz M,Richter T,Mühlhauser I

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:In Germany, rehabilitation is considered to be indicated after an acute hospital stay for the treatment of a severe cardiac condition. In comparative studies, at least 51% of German hospital patients with coronary heart disease (CHD) who were entitled to rehabilitative measures actually took part n rehabilit...

journal_title：Deutsches Arzteblatt international

authors： Schlitt A,Wischmann P,Wienke A,Hoepfner F,Noack F,Silber RE,Werdan K

更新日期：2015-08-03 00:00:00

abstract：BACKGROUND:Early gastro-esophageal cancer is staged as m1 to m3 depending on the infiltration of the anatomical layers of the mucosa or, analogously, as sm1 to sm3 depending on the depth of infiltration into the submucosa. The risk of lymph node metastases is low in mucosal carcinoma but increases with the depth of inf...

journal_title：Deutsches Arzteblatt international

authors： Gockel I,Hoffmeister A

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:Sunlight induces a wide variety of dermatoses. Their differential diagnosis is problematic not only because of similar phenotypes, but also because of confusing nomenclature and classification. METHODS:We selectively reviewed the literature of the past 20 years and describe the modern nosology of photoderma...

journal_title：Deutsches Arzteblatt international

authors： Lehmann P,Schwarz T

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Some hematological malignancies arise in persons with a hereditary predisposition. The hereditary nature of these diseases often goes unrecognized, particularly when symptoms begin in adulthood. METHODS:This review is based on pertinent publications retrieved by a selective search in PubMed. RESULTS:Many r...

journal_title：Deutsches Arzteblatt international

authors： Bochtler T,Haag GM,Schott S,Kloor M,Krämer A,Müller-Tidow C

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:Basically two types of sweating exist: thermoregulatory and emotional sweating. They are controlled by different centers: thermo regulatory sweating is regulated predominantly by the hypothalamus, emotional sweating predominantly by the limbic system. Enhanced sweating, called hyperhidrosis, can be generaliz...

journal_title：Deutsches Arzteblatt international

authors： Schlereth T,Dieterich M,Birklein F

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Isolated non-compaction cardiomyopathy (NCCM) was first described in 1984. This disorder, a primary genetic cardiomyopathy, is now attracting increased attention. METHOD:The current state of the epidemiology, pathogenesis, pathophysiology, clinical features, diagnosis, treatment, and prognosis of NCCM are d...

journal_title：Deutsches Arzteblatt international

authors： Engberding R,Stöllberger C,Ong P,Yelbuz TM,Gerecke BJ,Breithardt G

更新日期：2010-03-01 00:00:00