Complex-value coherence mapping reveals novel abnormal resting-state functional connectivity networks in task-specific focal hand dystonia.

abstract：:Given the increasing use of regenerative free muscle flaps for various reconstructive procedures and neuroprosthetic applications, there is great interest and value in their enhanced regeneration, revascularization, and reinnervation for improved functional recovery. Here, we implant polyimide-based mircroelectrodes o...

journal_title：Frontiers in neurology

authors： Srinivasan S,Vyas K,McAvoy M,Calvaresi P,Khan OF,Langer R,Anderson DG,Herr H

更新日期：2019-03-22 00:00:00

abstract：:Mutations in both copies (homozygous or compound heterozygous) of the gene encoding the lysosomal enzyme glucocerebrosidase, which cleaves the glycolipid glucocerebroside into glucose and ceramide cause Gaucher disease. However, multiple independent studies have also reported an association between GBA mutations and P...

journal_title：Frontiers in neurology

authors： Almeida Mdo R

更新日期：2012-04-27 00:00:00

abstract：:Ictal fear-a relatively rare phenomenon-is a semiological characteristic of epilepsy. Most patients with epilepsy with ictal fear have an epileptic zone in the mesial temporal lobe, which is the classical brain area involved in emotion processing. Herein, we report a case of epilepsy with ictal fear as the first manif...

journal_title：Frontiers in neurology

authors： Wang J,Wang Q,Wang M,Luan G,Zhou J,Guan Y,Yan Z

更新日期：2018-08-07 00:00:00

abstract：:Periodontitis is an oral inflammatory disease and may contribute to low-grade systemic inflammation. Based on the contribution of periodontitis to systemic inflammation and the potential role of systemic inflammation in neuroinflammation, many epidemiological studies have investigated a possible association between pe...

journal_title：Frontiers in neurology

authors： Nascimento PC,Castro MML,Magno MB,Almeida APCPSC,Fagundes NCF,Maia LC,Lima RR

更新日期：2019-04-24 00:00:00

abstract：:Cognitive impairment is prevalent and disabling in multiple sclerosis (MS) and is severely impacting quality of life (QoL). Aside its routine assessment in clinical care, it should more often be implemented as endpoint/outcome measure in clinical trials. However, a fundamental aspect-often neglected in clinical practi...

journal_title：Frontiers in neurology

authors： Beste C,Ziemssen T

更新日期：2020-08-28 00:00:00

abstract：:Background: Phosphatidylinositol binding clathrin assembly protein (PICALM) rs541458 C allele has been identified and validated to be associated with a reduction of Alzheimer's disease (AD) risk. Nevertheless, the exact mechanisms through which the variant exert its disease-relevant association remain to be elucidated...

journal_title：Frontiers in neurology

authors： Zhuang L,Liu X,Shi Y,Liu X,Luo B

更新日期：2019-05-08 00:00:00

abstract：:Mutations of the voltage-gated sodium channel SCN8A have been identified in approximately 1% of nearly 1,500 children with early-infantile epileptic encephalopathies (EIEE) who have been tested by DNA sequencing. EIEE caused by mutation of SCN8A is designated EIEE13 (OMIM #614558). Affected children have seizure onset...

journal_title：Frontiers in neurology

authors： Wagnon JL,Meisler MH

更新日期：2015-05-15 00:00:00

abstract：OBJECTIVES:Stroke can happen to people away from home. It is unknown whether non-resident and resident stroke patients have equal access to thrombolysis. MATERIALS AND METHODS:Consecutive patients cared for by the Stroke Emergency Mobile between 2011 and 2016 after prompting suspicion of acute stroke during the emerge...

journal_title：Frontiers in neurology

authors： Schlemm L,Turc G,Audebert HJ,Ebinger M

更新日期：2017-06-30 00:00:00

abstract：:Immune checkpoint inhibitors (ICI) are a novel class of antineoplastic treatment that enhances immunity against tumors. They are associated with immune adverse events, and several neurological syndromes have been described, including multiple sclerosis and atypical demyelination. We performed a systematic literature r...

journal_title：Frontiers in neurology

authors： Oliveira MCB,de Brito MH,Simabukuro MM

更新日期：2020-12-11 00:00:00

abstract：:Objectives: To report two novel DNA2 gene mutations causing early onset myopathy with cardiac involvement and late onset mitochondriopathy with rhabdomyolysis. Methods: We performed detailed clinical, muscle histopathology and molecular studies including mitochondrial gene NGS analysis in two patients (Patient 1 and 2...

journal_title：Frontiers in neurology

authors： González-Del Angel A,Bisciglia M,Vargas-Cañas S,Fernandez-Valverde F,Kazakova E,Escobar RE,Romero NB,Jardel C,Rucheton B,Stojkovic T,Malfatti E

更新日期：2019-10-04 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a non-destructive technique that is capable of localizing pathologies and assessing other anatomical features (e.g., tissue volume, microstructure, and white matter connectivity) in postmortem, ex vivo human brains. However, when brains are removed from the skull and cerebrospinal f...

journal_title：Frontiers in neurology

authors： Shatil AS,Matsuda KM,Figley CR

更新日期：2016-11-29 00:00:00

abstract：:Background: Following aneurysmal subarachnoid hemorrhage, peripherally-drawn lactic acid has been associated with poor outcomes; however, its clinical significance is unknown. We investigated admission factors and patient outcomes associated with serum lactic acid in this population. Methods: This was a retrospective ...

journal_title：Frontiers in neurology

authors： Poblete RA,Cen SY,Zheng L,Emanuel BA

更新日期：2018-07-23 00:00:00

abstract：:Background: Distal posterior inferior cerebellar artery (PICA) aneurysms are uncommon intracranial vascular lesions. The coincidence of these aneurysms and Arteriovenous malformation (AVM) is even more rare. Since 1956, a total of 57 cases of distal PICA aneurysms associated with AVM have been reported with clear and ...

journal_title：Frontiers in neurology

authors： Khayat HA,Hawkes CM,Algird AR

更新日期：2020-12-18 00:00:00

abstract：:The vestibulo-ocular reflex (VOR) consists of two components, the rotational VOR (rVOR) elicited by semicircular canal signals and the translational VOR (tVOR) elicited by otolith signals. Given the relevant role of the vertical tVOR in human walking, this study aimed at measuring the time delay of eye movements in re...

journal_title：Frontiers in neurology

authors： Kutz DF,Kolb FP,Glasauer S,Straka H

更新日期：2020-05-14 00:00:00

abstract：:Background: Previous studies conflicted in the association between intracranial atherosclerotic stenosis (ICAS) and the severity of white matter changes (WMC). Aims: We aimed to investigate the relationships between the severity of luminal stenosis and the hemodynamic significance of middle cerebral artery (MCA) steno...

journal_title：Frontiers in neurology

authors： Fang H,Leng X,Pu Y,Zou X,Pan Y,Song B,Soo YOY,Leung TWH,Wang C,Zhao X,Wang Y,Wang Y,Wong KS,Liu L,Xu Y,CICAS Study Group.

更新日期：2020-04-15 00:00:00

abstract：:Background: Subthalamic nucleus deep brain stimulation (STN-DBS) has been an established method in improvement of motor disabilities in Parkinson's disease (PD) patients. It has been also claimed to have an impact on balance and gait disorders in PD patients, but the previous results are conflicting. Objective: The ai...

journal_title：Frontiers in neurology

authors： Szlufik S,Kloda M,Friedman A,Potrzebowska I,Gregier K,Mandat T,Przybyszewski A,Dutkiewicz J,Figura M,Habela P,Koziorowski D

更新日期：2018-10-31 00:00:00

abstract：BACKGROUND:The present review investigated which findings in vascular imaging techniques can be used to predict clinical outcome and the risk of symptomatic intracerebral hemorrhage (sICH) in patients who underwent intravenous thrombolytic treatment. METHODS:Publications were searched, and the inclusion criteria were ...

journal_title：Frontiers in neurology

authors： Nogueira RC,Bor-Seng-Shu E,Saeed NP,Teixeira MJ,Panerai RB,Robinson TG

更新日期：2016-05-18 00:00:00

abstract：:Background: Trigeminal neuralgia (TN) is a recognized pain condition the treatment of which can be very challenging. Various surgical interventions can be applied in cases of therapy-resistance to drug treatments. The central lateral thalamotomy (CLT) against neurogenic (or neuropathic) pain is based on multiarchitect...

journal_title：Frontiers in neurology

authors： Gallay MN,Moser D,Jeanmonod D

更新日期：2020-04-17 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2018.00184.]. ...

journal_title：Frontiers in neurology

authors： Janca R,Krsek P,Jezdik P,Cmejla R,Tomasek M,Komarek V,Marusic P,Jiruska P

更新日期：2019-06-14 00:00:00

abstract：:In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the tempor...

journal_title：Frontiers in neurology

authors： Hinkley LB,Dolberg R,Honma S,Findlay A,Byl NN,Nagarajan SS

更新日期：2012-11-28 00:00:00

abstract：OBJECTIVE:Dizziness is a common reason patients present to doctors, but effective diagnostic tests and treatments for dizziness are underused. The internet is a way to disseminate medical information and is emerging as an intervention platform. The objective of this study was to describe internet searches for dizziness...

journal_title：Frontiers in neurology

authors： Kerber KA,Skolarus LE,Callaghan BC,Zheng K,Zhang Y,An LC,Burke JF

更新日期：2014-04-16 00:00:00

abstract：:Accurate prediction of the early stage of Alzheimer's disease (AD) is important but very challenging. The goal of this study was to utilize predictors for diagnosis conversion to AD based on integrating resting-state functional MRI (rs-fMRI) connectivity analysis and structural MRI (sMRI). We included 177 subjects in ...

journal_title：Frontiers in neurology

authors： Hojjati SH,Ebrahimzadeh A,Babajani-Feremi A

更新日期：2019-08-30 00:00:00

abstract：PURPOSE:Traumatic brain injury involving loss of consciousness has focal effects in the human brainstem, suggesting that it may have particular consequences for eye movement control. This hypothesis was investigated by measurements of vergence eye movement parameters. METHODS:Disparity vergence eye movements were meas...

journal_title：Frontiers in neurology

authors： Tyler CW,Likova LT,Mineff KN,Elsaid AM,Nicholas SC

更新日期：2015-02-03 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities. ADPKD is caused by mutations in either PKD1 or PKD2 genes that encode for integral membrane proteins Polycystin-1 (PC1) and Polycystin-2 (PC2), respectively. Ex...

journal_title：Frontiers in neurology

authors： Thomas C,Zühlsdorf A,Hörtnagel K,Mulahasanovic L,Grauer OM,Kümpers P,Wiendl H,Meuth SG

更新日期：2018-05-25 00:00:00

abstract：:Huntington's Disease (HD) is a genetic neurodegenerative disease caused by a CAG expansion in the gene encoding Huntingtin (Htt). It is characterized by chorea, cognitive, and psychiatric disorders. The most affected brain region is the striatum, and the clinical symptoms are directly correlated to the rate of striata...

journal_title：Frontiers in neurology

authors： Moumné L,Betuing S,Caboche J

更新日期：2013-10-23 00:00:00

abstract：:Microglia are activated during pathological events in the brain and are capable of releasing various types of inflammatory cytokines. Here, we demonstrate that the addition of 5% microglia activated by 1 μg/ml lipopolysaccharides (LPS) to hippocampal cultures upregulates Na(+) current densities (INavD) of bipolar as w...

journal_title：Frontiers in neurology

authors： Klapal L,Igelhorst BA,Dietzel-Meyer ID

更新日期：2016-03-30 00:00:00

abstract：:Glaucoma is a multifactorial syndrome in which the development of pro-apoptotic signals are the causes for retinal ganglion cell (RGC) loss. Most of the research progress in the glaucoma field have been based on experimentally inducible glaucoma animal models, which provided results about RGC loss after either the cra...

journal_title：Frontiers in neurology

authors： Tirendi S,Saccà SC,Vernazza S,Traverso C,Bassi AM,Izzotti A

更新日期：2020-12-01 00:00:00

abstract：:Background: Early imaging-based treatment response assessment of brain metastases following stereotactic radiosurgery (SRS) remains challenging. The aim of this study is to determine whether early (within 12 weeks) intratumoral changes in interstitial fluid pressure (IFP) and velocity (IFV) estimated from computationa...

journal_title：Frontiers in neurology

authors： Swinburne N,LoCastro E,Paudyal R,Oh JH,Taunk NK,Shah A,Beal K,Vachha B,Young RJ,Holodny AI,Shukla-Dave A,Hatzoglou V

更新日期：2020-05-28 00:00:00

abstract：:We present a case of a 43-year-old woman with a history of headaches and blurry vision. Ophthalmologic examination identified papilledema. MR imaging demonstrated a right parietal region mass with patchy areas of contrast enhancement and focal calcifications. Intraoperative examination and exploration revealed an extr...

journal_title：Frontiers in neurology

authors： Ballester LY,Dunbar E,Guha-Thakurta N,Henson JW,Chandler H,Watkins J,Fuller GN

更新日期：2018-08-27 00:00:00

abstract：:Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25-50% of cases. Most studies found the occurrence of posttraumatic hypopituitarism (PTHP) to be unrelated to injury sever...

journal_title：Frontiers in neurology

authors： Wilkinson CW,Pagulayan KF,Petrie EC,Mayer CL,Colasurdo EA,Shofer JB,Hart KL,Hoff D,Tarabochia MA,Peskind ER

更新日期：2012-02-07 00:00:00