Daily Pomegranate Intake Has No Impact on PSA Levels in Patients with Advanced Prostate Cancer - Results of a Phase IIb Randomized Controlled Trial.

abstract：:Introduction: Preoperative risk stratification is crucial for clinical treatment of endometrial cancer (EC). This study aimed to establish a model based on magnetic resonance imaging (MRI) and clinical factors for risk classification of EC. Materials and Methods: A total of 102 patients with pathologically proven Stag...

journal_title：Journal of Cancer

authors： Chen J,Gu H,Fan W,Wang Y,Chen S,Chen X,Wang Z

更新日期：2021-01-01 00:00:00

abstract：:Objectives: Chordomas are slow-growing malignancies that commonly affect vital neurological structures. These neoplasms are highly resistant to current chemotherapeutic regimens and often recur after surgical intervention. Therefore, there is an urgent need to identify molecular targets and more robust drugs to improv...

journal_title：Journal of Cancer

authors： Shen S,Dean DC,Yu Z,Hornicek F,Kan Q,Duan Z

更新日期：2020-01-01 00:00:00

abstract：:Non epithelial ovarian tumors represent a small group of rare gynecological cancers but they have a high incidence in young childbearing women. The recent years fertility preservation surgeries have become a common practice in specific ovarian malignancies when the patients wish to maintain their fertility. Specific t...

journal_title：Journal of Cancer

authors： Thomakos N,Malakasis A,Machairiotis N,Zarogoulidis P,Rodolakis A

更新日期：2018-11-24 00:00:00

abstract：BACKGROUND:Mitochondria play crucial roles in cell signaling events, interorganellar communication, aging, cell proliferation and apoptosis, and mitochondrial impairment has been shown to accelerate or modulate cancer progression. Ubiquitous mitochondrial creatine kinase (uMtCK) is predominantly localized in the interm...

journal_title：Journal of Cancer

authors： Amamoto R,Uchiumi T,Yagi M,Monji K,Song Y,Oda Y,Shiota M,Yokomizo A,Naito S,Kang D

更新日期：2016-01-01 00:00:00

abstract：:Colorectal cancer is a commonly diagnosed malignancy and also the major cause of death worldwide. Chemotherapy is the primary therapy for advanced colorectal cancer. Although oxaliplatin has potential effect in colorectal cancer therapy, the molecular mechanisms involved in its cytotoxic effects are not well elucidate...

journal_title：Journal of Cancer

authors： Evert J,Pathak S,Sun XF,Zhang H

更新日期：2018-05-22 00:00:00

abstract：:Purpose: Several new treatment options for patients with metastatic castration resistant prostate cancer (mCRPC) have been approved within the last years - among them cabazitaxel (CAB), abiraterone acetate, enzalutamide, and radium-223. The aim of this study was to assess factors predictive for efficacy of CAB. Method...

journal_title：Journal of Cancer

authors： Zschäbitz S,Vallet S,Hadaschik B,Debatin D,Fuxius S,Karcher A,Pahernik S,Spath C,Duensing S,Jäger D,Hohenfellner M,Grüllich C

更新日期：2017-02-11 00:00:00

abstract：OBJECTIVE(S):To assess skeletal wide fracture location and time of fracture after cancer treatment Study Design: One hundred thirty-nine women diagnosed with breast or gynecologic cancer between 2003 and 2012 that subsequently had a radiologic diagnosis of fracture were identified retrospectively using electronic medic...

journal_title：Journal of Cancer

authors： Hui SK,Arentsen L,Wilcox A,Shanley R,Yee D,Ghebre R

更新日期：2015-01-01 00:00:00

abstract：:Background: Colorectal cancer (CRC) has been reconsidered as a heterogeneous disease. Among advances of genomic analysis in CRC, the sidedness of tumors (left-sided colon vs. right-sided colon) and microsatellite instability (MSI)-high (H) tumors have been highlighted. Methods: We analyzed 153 CRC patients who were av...

journal_title：Journal of Cancer

authors： Kim ST,Lee SJ,Lee J,Park SH,Park JO,Lim HY,Kang WK,Park YS

更新日期：2017-08-23 00:00:00

abstract：:Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies. The metabolomic approaches are developed to discover the novel biomarkers of PDAC. Methods: 550 preoperative, postoperative PDAC and normal controls (NCs) serums were employed to characterize metabolic alterations in ...

journal_title：Journal of Cancer

authors： Zhang X,Shi X,Lu X,Li Y,Zhan C,Akhtar ML,Yang L,Bai Y,Zhao J,Wang Y,Yao Y,Li Y,Nie H

更新日期：2020-05-19 00:00:00

abstract：:Many studies, using different chemical agents, have shown excellent cancer prevention efficacy in mice and rats. However, equivalent tests of cancer prevention in humans require decades of intake of the agents while the rodents' short lifespans cannot give us information of the long-term safety. Therefore, animals wit...

journal_title：Journal of Cancer

authors： Ma Y,Jia Y,Chen L,Ezeogu L,Yu B,Xu N,Liao DJ

更新日期：2015-09-01 00:00:00

abstract：:Metabolic syndrome has been previously identified as a risk factor for breast cancer and is increasingly a public health concern. This study aims to investigate the prevalence of metabolic syndrome and its components among primary breast cancer and control population. The clinical data of metabolic syndrome and its co...

journal_title：Journal of Cancer

authors： Wu YT,Luo QQ,Li X,Arshad B,Xu Z,Ran L,Zhao CX,Wu H,Shi YL,Chen HR,Li H,Li HY,Wu KN,Kong LQ

更新日期：2018-01-01 00:00:00

abstract：:Tumor growth depends on angiogenesis, the growth of new blood vessels. Complement factor H (CFH) is a plasma glycoprotein that functions as a regulator of the complement system. The aim of this study is to delineate the role of CFH in angiogenesis. A conditional null allele of the Cfh gene was generated in C57BL/6J mi...

journal_title：Journal of Cancer

authors： Liu J,Hoh J

更新日期：2017-07-15 00:00:00

abstract：:Background & Aims: Primary tumors of colorectal carcinoma (CRC) with liver metastasis might gain some liver-specific characteristics to adapt the liver micro-environment. This study aims to reveal potential liver-like transcriptional characteristics associated with the liver metastasis in primary colorectal carcinoma....

journal_title：Journal of Cancer

authors： Cheng J,Song X,Ao L,Chen R,Chi M,Guo Y,Zhang J,Li H,Zhao W,Guo Z,Wang X

更新日期：2018-04-06 00:00:00

abstract：:Purpose: MicroRNAs (miRNAs) are key regulators of the growth and development of a wide range of cancer types such as colorectal cancer (CRC). A number of previously studies have observed that the levels of miR-365a-3p expression are dysregulated in many cancers, but the specific role of this miRNA in CRC and its assoc...

journal_title：Journal of Cancer

authors： Hong YG,Xin C,Zheng H,Huang ZP,Yang Y,Zhou JD,Gao XH,Hao L,Liu QZ,Zhang W,Hao LQ

更新日期：2020-03-26 00:00:00

abstract：:Objective: Although previous studies suggest that previous pulmonary tuberculosis was associated with increased risk of lung cancer. It remains controversial whether pulmonary tuberculosis is a risk factor for lung cancer. Our study was aimed to examine the association between pulmonary tuberculosis and lung cancer ri...

journal_title：Journal of Cancer

authors： Oh CM,Roh YH,Lim D,Kong HJ,Cho H,Hwangbo B,Won YJ,Jung KW,Oh K

更新日期：2020-01-20 00:00:00

abstract：:For many years, the medical treatment of breast cancer was reliant solely on cytotoxic chemotherapy. However, over the past twenty years, treatment has evolved to a more target-directed approach. We now employ tailored therapy based on the presence or absence of receptors for estrogen, progesterone, and human epiderma...

journal_title：Journal of Cancer

authors： Tinoco G,Warsch S,Glück S,Avancha K,Montero AJ

更新日期：2013-01-01 00:00:00

abstract：:Esophageal cancer is an aggressive disease featured by early lymphatic and hematogenous dissemination, and is the sixth leading cause of cancer-related deaths worldwide. The proper formation of apicobasal polarity is essential for normal epithelium physiology and tissue homeostasis, while loss of polarity is a hallmar...

journal_title：Journal of Cancer

authors： Li XM,Wang H,Zhu LL,Zhao RZ,Ji HL

更新日期：2015-06-11 00:00:00

abstract：:Yes-associated protein (YAP) is a transcriptional coactivator that promotes cell proliferation, migration, and tissue homeostasis in colorectal cancer (CRC). Here, we established 5-Fu resistant CRC cell line (SW620R) and examined the role of YAP in chemotherapy resistance. We showed that YAP promoted cell proliferatio...

journal_title：Journal of Cancer

authors： Huang C,Chen Z,Yang C,Chen L,Lai C,Zhang Y,Yuan W,Jeong JH

更新日期：2020-07-11 00:00:00

abstract：:Lung cancer is the most common malignancy in China and is associated with a poor survival rate amongst Han Chinese. The high mortality is largely attributed to late-stage diagnosis, when treatment is largely ineffective. Identification of genetic variants could potentially assist with earlier diagnosis and thus more e...

journal_title：Journal of Cancer

authors： Hu W,Tang CH,Chen HT,Zhao J,Jin L,Kang L,Wu Y,Ying P,Wang CQ,Su CM

更新日期：2019-06-02 00:00:00

abstract：PURPOSE:To evaluate acute hypersensitivity reactions at the UCSD Moores Cancer Center in San Diego, compare our findings to those reported previously in the literature, and examine the effectiveness of the objective grading scale as represented by the Common Terminology Criteria for Adverse Events (CTCAE). PATIENTS AN...

journal_title：Journal of Cancer

authors： Demoor PA,Matusov Y,Kelly C,Kolan S,Barnachea L,Bazhenova LA

更新日期：2011-03-10 00:00:00

abstract：:Colorectal cancer (CRC) is an important health issue worldwide, accounting for the third place of cancer incidence. Chronic inflammation, as seen in Crohn's disease and ulcerative colitis, is the most important risk factor for developing CRC, as it favours neoplastic transformation by enhancing epithelial cell turnove...

journal_title：Journal of Cancer

authors： Figueroa-González G,García-Castillo V,Coronel-Hernández J,López-Urrutia E,León-Cabrera S,Arias-Romero LE,Terrazas LI,Rodríguez-Sosa M,Campos-Parra AD,Zúñiga-Calzada E,Lopez-Camarillo C,Morales-González F,Jacobo-Herrera NJ,Pérez

更新日期：2016-07-25 00:00:00

abstract：:Cancer-associated fibroblasts (CAFs), which are an important component of the tumor microenvironment, have been identified in the blood circulation of patients with cancer metastasis, and metastatic cancer cells can recruit circulating CAFs. However, primary carcinoma sites usually regulate the behavior of metastatic ...

journal_title：Journal of Cancer

authors： Zhang YF,Zhou YZ,Zhang B,Huang SF,Li PP,He XM,Cao GD,Kang MX,Dong X,Wu YL

更新日期：2019-07-23 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC), is one of the most common malignant tumor in southern China and southeast Asia. MYH10 is a coding gene of the NMMHC-IIB protein. Previous studies have shown that MYH10 expression was up-regulated in breast cancer, glioma and meningioma. Moreover, it was targeted by miR200 family. Howeve...

journal_title：Journal of Cancer

authors： Liu W,Cai T,Li L,Chen H,Chen R,Zhang M,Zhang W,Zhao L,Xiong H,Qin P,Gao X,Jiang Q

更新日期：2020-03-04 00:00:00

abstract：:Several studies have reported the association between MAPK signaling pathway gene polymorphisms and papillary thyroid carcinoma (PTC). KRAS gene, an oncogene from the mammalian RAS gene family plays an important role in the MAPK pathway. This study aimed to identify the potential association of KRAS gene polymorphisms...

journal_title：Journal of Cancer

authors： Ning L,Rao W,Yu Y,Liu X,Pan Y,Ma Y,Liu R,Zhang S,Sun H,Yu Q

更新日期：2016-12-09 00:00:00

abstract：:Multidrug resistance is a major obstacle to the effective treatment of esophageal carcinoma. It occurs more readily in hypoxia and acidosis microenvironment. TTLL6 is one of Tubulin tyrosine ligase-like family members. In this study, the effect of TTLL6 on the regulation of cisplatin (CDDP) sensitivity was evaluated i...

journal_title：Journal of Cancer

authors： Qiu Y,Wu C,Li J,Tang M,Zhang S,Jing T,Liao Y,Wang H

更新日期：2020-09-30 00:00:00

abstract：:Purpose: Aim of this study was to comprehensively analyze BRCA1-associated protein-1 (BAP1) somatic mutation in clear cell renal cell carcinoma (ccRCC) and explore potential therapeutic pathways and molecules. Patients and methods: In this study, we analyzed 445 ccRCC cases from The Cancer Genome Atlas (TCGA). Compreh...

journal_title：Journal of Cancer

authors： Jin S,Wu J,Zhu Y,Gu W,Wan F,Xiao W,Dai B,Zhang H,Shi G,Shen Y,Zhu Y,Ye D

更新日期：2018-10-18 00:00:00

abstract：:Endocrine resistance in hormone receptor positive breast cancer patients urges us to develop novel approaches such as inhibitors of the cyclin-dependent kinases (CDK) 4/6 to reverse its resistance. Nowadays, three selective CDK4/6 inhibitors (Palbociclib, Ribociclib and Abemaciclib) are approved by Federal Drug Admini...

journal_title：Journal of Cancer

authors： Chen X,Xu D,Li X,Zhang J,Xu W,Hou J,Zhang W,Tang J

更新日期：2019-10-21 00:00:00

abstract：:Background: Colorectal cancer (CRC) remains to be one of the most common malignancies worldwide. Various studies have demonstrated that microRNAs (miRs) play a critical role in regulating cancer progression and sensitivity to chemoradiotherapy. miR-1 was found to be aberrantly expressed in CRC. However, it has not bee...

journal_title：Journal of Cancer

authors： Wu Y,Pu N,Su W,Yang X,Xing C

更新日期：2020-06-07 00:00:00

abstract：:Objective: There are controversial indications for neoadjuvant chemotherapy (NAT) in the treatment of locally advanced gastric cancer (LAGC). Here, we aimed to identify indications for NAT based on pre-treatment clinicopathological and laboratory parameters. Methods: This study included a retrospective cohort of 1083 ...

journal_title：Journal of Cancer

authors： Wang Y,Zhang J,Guo S,Meng XY,Zheng ZC,Zhao Y

更新日期：2020-08-18 00:00:00

abstract：:In 2006, a remarkable collaboration between University of Texas MD Anderson Cancer Center clinicians and Texas and New Mexico State legislators led to the formation of a dedicated IBC Research Program and Clinic at MD Anderson. This initiative provided funding and infrastructure to foster coordination of an IBC World ...

journal_title：Journal of Cancer

authors： Woodward WA,Cristofanilli M,Merajver SD,Van Laere S,Pusztai L,Bertucci F,Berditchevski F,Polyak K,Overmoyer B,Devi GR,Sterneck E,Schneider R,Debeb BG,Wang X,van Golen KL,El-Zein R,Rahal OM,Alexander A,Reuben JM,Kris

更新日期：2017-10-09 00:00:00