Cellular and molecular basis of cerebellar development.

abstract：:Adult born neurons in the hippocampus show species-specific differences in their numbers, the pace of their maturation and their spatial distribution. Here, we present quantitative data on adult hippocampal neurogenesis in a New World primate, the common marmoset (Callithrix jacchus) that demonstrate parts of the line...

journal_title：Frontiers in neuroanatomy

authors： Amrein I,Nosswitz M,Slomianka L,van Dijk RM,Engler S,Klaus F,Raineteau O,Azim K

更新日期：2015-06-29 00:00:00

abstract：:Brain tissue contains autofluorescing elements that potentially impede accurate identification of neurons when visualized with fluorescent microscopy. Age-related accumulation of molecules with autofluorescent properties, such as lipofuscin, can possess spectral profiles that invade the typical emission range of fluor...

journal_title：Frontiers in neuroanatomy

authors： Pyon WS,Gray DT,Barnes CA

更新日期：2019-07-18 00:00:00

abstract：:Introduction: Knowledge of the neuro-anatomical architecture of the inner ear contributes to the improvement and development of cochlear and vestibular implants. The present knowledge is mainly based on two-dimensional images (histology) or derived models that simplify the complexity of this architecture. This study i...

journal_title：Frontiers in neuroanatomy

authors： van den Boogert T,van Hoof M,Handschuh S,Glueckert R,Guinand N,Guyot JP,Kingma H,Perez-Fornos A,Seppen B,Johnson Chacko L,Schrott-Fischer A,van de Berg R

更新日期：2018-05-22 00:00:00

abstract：:Previous developmental studies of the thalamus (alar part of the diencephalic prosomere p2) have defined the molecular basis for the acquisition of the thalamic competence (preparttening), the subsequent formation of the secondary organizer in the zona limitans intrathalamica, and the early specification of two antero...

journal_title：Frontiers in neuroanatomy

authors： Bandín S,Morona R,González A

更新日期：2015-08-10 00:00:00

abstract：:Analyses of mice carrying a deletion of the pan-neurotrophin receptor p75NTR have allowed identifying p75NTR as an important structural regulator of the hippocampus. Most of the previous analyses were done using p75NTR (ExIII) knockout mice which still express the short isoform of p75NTR. To scrutinize the role of p75...

journal_title：Frontiers in neuroanatomy

authors： Poser R,Dokter M,von Bohlen Und Halbach V,Berger SM,Busch R,Baldus M,Unsicker K,von Bohlen Und Halbach O

更新日期：2015-05-27 00:00:00

abstract：:Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has been hypothesized to confine biochemical and electric signals within...

journal_title：Frontiers in neuroanatomy

authors： Adrian M,Kusters R,Wierenga CJ,Storm C,Hoogenraad CC,Kapitein LC

更新日期：2014-12-04 00:00:00

abstract：:Gestational exposure to valproic acid (VPA) is known to cause behavioral deficits of sociability, matching similar alterations in human autism spectrum disorder (ASD). Available data are scarce on the neuromorphological changes in VPA-exposed animals. Here, we focused on alterations of the dopaminergic system, which i...

journal_title：Frontiers in neuroanatomy

authors： Ádám Á,Kemecsei R,Company V,Murcia-Ramón R,Juarez I,Gerecsei LI,Zachar G,Echevarría D,Puelles E,Martínez S,Csillag A

更新日期：2020-06-05 00:00:00

abstract：:Blue tits (Cyanistes coeruleus) are songbirds, used as model animals in numerous studies covering a wide field of research. Nevertheless, the distribution of neuropeptides in the brain of this avian species remains largely unknown. Here we present some of the first results on distribution of Vasotocine (AVT) and Vasoa...

journal_title：Frontiers in neuroanatomy

authors： Montagnese CM,Székely T,Csillag A,Zachar G

更新日期：2015-07-14 00:00:00

abstract：:Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

journal_title：Frontiers in neuroanatomy

authors： Herculano-Houzel S,Manger PR,Kaas JH

更新日期：2014-08-11 00:00:00

abstract：:Most studies in mammals and birds have demonstrated common patterns of hypothalamic development highlighted by the combination of developmental regulatory genes (genoarchitecture), supporting the notion of the hypothalamus as a component of the secondary prosencephalon, topologically rostral to the diencephalon. In ou...

journal_title：Frontiers in neuroanatomy

authors： Domínguez L,González A,Moreno N

更新日期：2015-02-03 00:00:00

abstract：:Oxytocin, a neuropeptide and peptide hormone, is produced by neurons in the hypothalamus and released by the posterior pituitary to control breastfeeding and labor. Recent studies have revealed that oxytocin in the central nervous system is also involved in modulating social interaction. To understand the potential ro...

journal_title：Frontiers in neuroanatomy

authors： Liao PY,Chiu YM,Yu JH,Chen SK

更新日期：2020-10-19 00:00:00

abstract：:The last 140 years have seen considerable advances in knowledge of central nervous system tumors. However, the main tumor types had already been described during the early years of the twentieth century. The studies of Dr. Pío del Río Hortega have been ones of the most exhaustive histology and cytology-based studies o...

journal_title：Frontiers in neuroanatomy

authors： Ramon Y Cajal Agüeras S

更新日期：2016-03-01 00:00:00

abstract：:Experimentalallergic encephalomyelitis (EAE) is an animal model for inflammatory demyelinating autoimmune disease, i.e., multiple sclerosis (MS). In the present study, we investigated the antineuroinflammatory/neuroprotective effects of C16, an ανβ3 integrin-binding peptide, and recombinant rat ciliary neurotrophic fa...

journal_title：Frontiers in neuroanatomy

authors： Fang M,He D,Zhang F,Hu Z,Yang J,Jiang H,Han S

更新日期：2013-12-30 00:00:00

abstract：:In rodents, sexual behavior depends on the adequate detection of sexually relevant stimuli. The olfactory bulb (OB) is a region of the adult mammalian brain undergoing constant cell renewal by continuous integration of new granular and periglomerular neurons in the accessory (AOB) and main (MOB) olfactory bulbs. The p...

journal_title：Frontiers in neuroanatomy

authors： Portillo W,Unda N,Camacho FJ,Sánchez M,Corona R,Arzate DM,Díaz NF,Paredes RG

更新日期：2012-07-06 00:00:00

abstract：:Most terrestrial animals demonstrate an autonomic reflex that facilitates survival during prolonged submersion under water. This diving response is characterized by bradycardia, apnea and selective increases in peripheral vascular resistance. Stimulation of the nose and nasal passages is thought to be primarily respon...

journal_title：Frontiers in neuroanatomy

authors： McCulloch PF,Lahrman KA,DelPrete B,DiNovo KM

更新日期：2018-11-13 00:00:00

abstract：:Perinatal asphyxia (PA) is an obstetric complication that strongly affects the CNS. The endocannabinoid system (ECS) is a lipid transmitter system involved in several physiological processes including synaptic plasticity, neurogenesis, memory, and mood. Endocannabinoids, and other acylethanolamides (AEs) without endoc...

journal_title：Frontiers in neuroanatomy

authors： Blanco E,Galeano P,Holubiec MI,Romero JI,Logica T,Rivera P,Pavón FJ,Suarez J,Capani F,Rodríguez de Fonseca F

更新日期：2015-11-03 00:00:00

abstract：:Diffusion tensor imaging (DTI) and tractography offer the unique possibility to visualize the developing white matter macroanatomy of the human fetal brain in vivo and in utero and are currently under investigation for their potential use in the diagnosis of developmental pathologies of the human central nervous syste...

journal_title：Frontiers in neuroanatomy

authors： Mitter C,Jakab A,Brugger PC,Ricken G,Gruber GM,Bettelheim D,Scharrer A,Langs G,Hainfellner JA,Prayer D,Kasprian G

更新日期：2015-12-24 00:00:00

abstract：:Hibernating mammals undergo torpor periods characterized by a general decrease in body temperature, metabolic rate, and brain activity accompanied by complex adaptive brain changes that appear to protect the brain from extreme conditions of hypoxia and low temperatures. These processes are accompanied by morphological...

journal_title：Frontiers in neuroanatomy

authors： León-Espinosa G,DeFelipe J,Muñoz A

更新日期：2019-11-19 00:00:00

abstract：:Over the last 60 years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioral pathologies, the cerebellum is a natural home for studies of cell specifi...

journal_title：Frontiers in neuroanatomy

authors： Basson MA,Wingate RJ

更新日期：2013-09-03 00:00:00

abstract：:Really interesting new gene (RING) finger protein is a type of zinc-binding motif found in a large family of functionally distinct proteins. RING finger proteins are involved in diverse cellular processes including apoptosis, DNA repair, cell cycle, signal transduction, tumour suppressor, vesicular transport, and pero...

journal_title：Frontiers in neuroanatomy

authors： Cham KL,Soga T,Parhar IS

更新日期：2017-08-31 00:00:00

abstract：:Early telencephalic development involves the migration of diverse cell types that can be identified by specific molecular markers. Most prominent among them are Cajal-Retzius (CR) cells that emanate mainly from the cortical hem and to a lesser extent from rostrolateral, septal and caudo-medial regions. One additional ...

journal_title：Frontiers in neuroanatomy

authors： Frade-Pérez MD,Miquelajáuregui A,Varela-Echavarría A

更新日期：2017-11-01 00:00:00

abstract：:Birds use various vocalizations to communicate with one another, and some are acquired through learning. So far, three families of birds (songbirds, parrots, and hummingbirds) have been identified as having vocal learning ability. Previously, we found that cadherins, a large family of cell-adhesion molecules, show voc...

journal_title：Frontiers in neuroanatomy

authors： Matsunaga E,Okanoya K

更新日期：2011-04-20 00:00:00

abstract：:The mammalian oculomotor nucleus receives a strong γ-aminobutyric acid (GABA)ergic synaptic input, whereas such projections have rarely been reported in fish. In order to determine whether this synaptic organization is preserved across vertebrates, we investigated the GABAergic projections to the oculomotor nucleus in...

journal_title：Frontiers in neuroanatomy

authors： Luque MA,Torres-Torrelo J,Carrascal L,Torres B,Herrero L

更新日期：2011-02-04 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, the pathogenesis of PD re...

journal_title：Frontiers in neuroanatomy

authors： Blesa J,Przedborski S

更新日期：2014-12-15 00:00:00

abstract：:The artiodactyl brain has multiple levels of vascular pooling and the rostral epidural rete mirabile (RERM) at its base. The current study is the first of its kind to precisely demonstrate the arterial vasculature of the dromedary brain, utilizing a new casting method with colored latex and epoxy paint. In total, 35 f...

journal_title：Frontiers in neuroanatomy

authors： Al Aiyan A,Menon P,AlDarwich A,Almuhairi F,Alnuaimi S,Bulshawareb A,Qablan M,Shehab S

更新日期：2019-07-05 00:00:00

abstract：:Onuf's nucleus is a small group of neurons located in the ventral horns of the sacral spinal cord. The motor neurons (MNs) of Onuf's nucleus innervate striated voluntary muscles of the pelvic floor and are histologically and biochemically comparable to the other somatic spinal MNs. However, curiously, these neurons al...

journal_title：Frontiers in neuroanatomy

authors： Schellino R,Boido M,Vercelli A

更新日期：2020-09-04 00:00:00

abstract：:The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved ...

journal_title：Frontiers in neuroanatomy

authors： Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

更新日期：2018-11-26 00:00:00

abstract：:The auditory system contains a diverse array of interconnected anatomical structures that mediate the perception of sound. The cochlear nucleus of the hindbrain serves as the initial site of convergence for auditory stimuli, while the inferior colliculus of the midbrain serves as an integration and relay station for a...

journal_title：Frontiers in neuroanatomy

authors： Brown S,Zervas M

更新日期：2017-08-22 00:00:00

abstract：:Until recently it was widely believed that the ability of female mammals (with the likely exception of women) to identify and seek out a male breeding partner relied on the detection of non-volatile male pheromones by the female's vomeronasal organ (VNO) and their subsequent processing by a neural circuit that include...

journal_title：Frontiers in neuroanatomy

authors： Baum MJ

更新日期：2012-06-05 00:00:00

abstract：:Hippocampal sclerosis is the most frequent pathology encountered in resected mesial temporal structures from patients with intractable temporal lobe epilepsy (TLE). Here, we have used stereological methods to compare the overall density of synapses and neurons between non-sclerotic and sclerotic hippocampal tissue obt...

journal_title：Frontiers in neuroanatomy

authors： Alonso-Nanclares L,Kastanauskaite A,Rodriguez JR,Gonzalez-Soriano J,Defelipe J

更新日期：2011-02-24 00:00:00