Salsolinol modulation of dopamine neurons.

abstract：:Decision-making is an ethologically adaptive construct that is impaired in multiple psychiatric disorders. Activity within the mesocorticolimbic dopamine system has been traditionally associated with decision-making. The endocannabinoid system through its actions on inhibitory and excitatory synapses modulates dopamin...

journal_title：Frontiers in behavioral neuroscience

authors： Hernandez G,Cheer JF

更新日期：2015-12-17 00:00:00

abstract：:Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative SD exacerbates cognitive impairment induced by isoflurane. In th...

journal_title：Frontiers in behavioral neuroscience

authors： Zhang K,Lian N,Ding R,Guo C,Dong X,Li Y,Wei S,Jiao Q,Yu Y,Shen H

更新日期：2020-11-23 00:00:00

abstract：:Numerous studies show that sleep deprivation (SD) impacts negatively on cognitive processes, including learning and memory. Memory formation encompasses distinct phases of which acquisition, consolidation and retrieval are better known. Previous studies with pre-training SD induced by the platform method have shown im...

journal_title：Frontiers in behavioral neuroscience

authors： Rossi VC,Tiba PA,Moreira KD,Ferreira TL,Oliveira MG,Suchecki D

更新日期：2014-11-07 00:00:00

abstract：:Space and shape are distinct perceptual categories. In language, perceptual information can also be used to describe abstract semantic concepts like a "rising income" (space) or a "square personality" (shape). Despite being inherently concrete, co-speech gestures depicting space and shape can accompany concrete or abs...

journal_title：Frontiers in behavioral neuroscience

authors： Nagels A,Chatterjee A,Kircher T,Straube B

更新日期：2013-12-18 00:00:00

abstract：:Negative social experiences during adolescence increase the risk of psychiatric disorders in adulthood. Using "resident-intruder" stress, the present study aimed to investigate the effects of adolescent social defeat on emotional and cognitive symptoms associated with psychiatric disorders during adulthood and the eff...

journal_title：Frontiers in behavioral neuroscience

authors： Zhang F,Yuan S,Shao F,Wang W

更新日期：2016-07-20 00:00:00

abstract：:In male rats, copulation to satiety induces a long-lasting sexual inhibitory state, considered to rely on a decreased sexual motivation. Dopaminergic transmission at the mesolimbic system plays a central role in the regulation of male sexual motivation. Endocannabinoids (eCBs) modulate the activity of the mesolimbic s...

journal_title：Frontiers in behavioral neuroscience

authors： Canseco-Alba A,Rodríguez-Manzo G

更新日期：2019-08-14 00:00:00

abstract：:The ability to accurately integrate or bind stimuli from more than one sensory modality is highly dependent on the features of the stimuli, such as their intensity and relative timing. Previous studies have demonstrated that the ability to perceptually bind stimuli is impaired in various clinical conditions such as au...

journal_title：Frontiers in behavioral neuroscience

authors： Schormans AL,Allman BL

更新日期：2018-10-31 00:00:00

abstract：:Animals must make constant decisions whether to respond to external sensory stimuli or not to respond. The activation of positive and/or negative reinforcers might bias the behavioral response towards approach or aversion. To analyze whether the activation of the octopaminergic neurotransmitter system can shift the de...

journal_title：Frontiers in behavioral neuroscience

authors： Claßen G,Scholz H

更新日期：2018-07-03 00:00:00

abstract：:Damage involving the anterior thalamic and adjacent rostral thalamic nuclei may result in a severe anterograde amnesia, similar to the amnesia resulting from damage to the hippocampal formation. Little is known, however, about the information represented in these nuclei. To redress this deficit, we recorded units in t...

journal_title：Frontiers in behavioral neuroscience

authors： Jankowski MM,Passecker J,Islam MN,Vann S,Erichsen JT,Aggleton JP,O'Mara SM

更新日期：2015-10-13 00:00:00

abstract：:The physiological role of synaptic zinc has remained largely enigmatic since its initial detection in hippocampal mossy fibers over 50 years ago. The past few years have witnessed a number of studies highlighting the ability of zinc ions to regulate ion channels and intracellular signaling pathways implicated in neuro...

journal_title：Frontiers in behavioral neuroscience

authors： Sindreu C,Storm DR

更新日期：2011-11-09 00:00:00

abstract：:Background: Women are twice as likely as men to develop major depression. The brain mechanisms underlying this sex disparity are not clear. Disruption of the glutamate-glutamine cycle has been implicated in psychiatric disturbances. This study identifies sex-based impairments in the glutamate-glutamine cycle involving...

journal_title：Frontiers in behavioral neuroscience

authors： Rappeneau V,Blaker A,Petro JR,Yamamoto BK,Shimamoto A

更新日期：2016-12-06 00:00:00

abstract：:Background: Hypothesis-driven functional connectivity (FC) analyses have revealed abnormal functional interaction of regions or networks involved in pain processing in episodic migraine patients. We aimed to investigate the resting-state FC patterns in episodic migraine by combining data-driven voxel-wise degree centr...

journal_title：Frontiers in behavioral neuroscience

authors： Ke J,Yu Y,Zhang X,Su Y,Wang X,Hu S,Dai H,Hu C,Zhao H,Dai L

更新日期：2020-10-06 00:00:00

abstract：:Testosterone reduces anxiety-like behaviors in rodents and increases exploration of anxiogenic parts of the environment. Effects of testosterone on innate defensive behaviors remain understudied. Here, we demonstrate that exogenous testosterone reduces aversion to cat odor in male mice. This is reflected as increased ...

journal_title：Frontiers in behavioral neuroscience

authors： Tong WH,Abdulai-Saiku S,Vyas A

更新日期：2019-02-26 00:00:00

abstract：:Adolescent behavior is typified by increased risk-taking, reward- and novelty-seeking, as well as an augmented need for social and environmental stimulation. This behavioral phenotype may result from alterations in outcome valuation or reward learning. In the present set of experiments, we directly compared adult and ...

journal_title：Frontiers in behavioral neuroscience

authors： Stolyarova A,Izquierdo A

更新日期：2015-05-07 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a trophic factor regulating cell survival and synaptic plasticity. Recent findings indicate that BDNF could be a potential regulatory factor for cognitive functioning in normal and/or neuropathological conditions. With regard to neurological disorders, recent data suggest th...

journal_title：Frontiers in behavioral neuroscience

authors： Costa A,Peppe A,Carlesimo GA,Zabberoni S,Scalici F,Caltagirone C,Angelucci F

更新日期：2015-09-15 00:00:00

abstract：:There is conflicting evidence regarding whether calcium-permeable receptors are removed during group I mGluR-mediated synaptic depression. In support of this hypothesis, AMPAR rectification, a correlative index of the synaptic expression of GluA2-lacking calcium-permeable AMPARs (CP-AMPARs), is known to decrease after...

journal_title：Frontiers in behavioral neuroscience

authors： Park K,Song S,Hong I,Song B,Kim J,Park S,Lee J,Song S,An B,Kim J,Lee CJ,Shin KS,Choi S,Lee S

更新日期：2014-08-08 00:00:00

abstract：:DARPP-32 (PPP1R1B) was discovered as a substrate of cAMP-dependent protein kinase (PKA) enriched in dopamine-innervated brain areas. It is one of three related, PKA-regulated inhibitors of protein phosphatase-1 (PP1). These inhibitors seem to have appeared in early vertebrate ancestors, possibly Gnathostomes. DARPP-32...

journal_title：Frontiers in behavioral neuroscience

authors： Yger M,Girault JA

更新日期：2011-09-08 00:00:00

abstract：:Animals rely on sensory feedback from their environment to guide locomotion. For instance, visually guided animals use patterns of optic flow to control their velocity and to estimate their distance to objects (e.g., Srinivasan et al., 1991, 1996). In this study, we investigated how acoustic information guides locomot...

journal_title：Frontiers in behavioral neuroscience

authors： Warnecke M,Lee WJ,Krishnan A,Moss CF

更新日期：2016-04-25 00:00:00

abstract：:Problematic alcohol drinking and alcohol dependence are an increasing health problem worldwide. Alcohol abuse is responsible for approximately 5% of the total deaths in the world, but addictive consumption of it has a substantial impact on neurological and memory disabilities throughout the population. One of the bett...

journal_title：Frontiers in behavioral neuroscience

authors： Mira RG,Lira M,Tapia-Rojas C,Rebolledo DL,Quintanilla RA,Cerpa W

更新日期：2020-01-24 00:00:00

abstract：:To study visual learning in honey bees, we developed a virtual reality (VR) system in which the movements of a tethered bee walking stationary on a spherical treadmill update the visual panorama presented in front of it (closed-loop conditions), thus creating an experience of immersion within a virtual environment. In...

journal_title：Frontiers in behavioral neuroscience

authors： Buatois A,Flumian C,Schultheiss P,Avarguès-Weber A,Giurfa M

更新日期：2018-07-13 00:00:00

abstract：:The Supplementary Eye Field (SEF) and the Frontal Eye Field (FEF) have been described as participating in gaze shift control. Recent evidence suggests, however, that other areas of the dorsomedial prefrontal cortex also influence gaze shift. Herein, we have investigated electrically evoked ear- and eye movements from ...

journal_title：Frontiers in behavioral neuroscience

authors： Lanzilotto M,Perciavalle V,Lucchetti C

更新日期：2015-01-30 00:00:00

abstract：:Magnetoreception can play a substantial role in long distance navigation by animals. I hypothesize that locomotion guided by a magnetic compass sense could also play a role in short distance navigation. Animals identify mates, prey, or other short distance navigational goals using different sensory modalities (olfacti...

journal_title：Frontiers in behavioral neuroscience

authors： Wyeth RC

更新日期：2010-07-30 00:00:00

abstract：:In animals, emotional memory is classically assessed through pavlovian fear conditioning in which a neutral novel stimulus (conditioned stimulus) is paired with an aversive unconditioned stimulus. After conditioning, the conditioned stimulus elicits a fear response characterized by a wide range of behavioral and physi...

journal_title：Frontiers in behavioral neuroscience

authors： Hegoburu C,Shionoya K,Garcia S,Messaoudi B,Thévenet M,Mouly AM

更新日期：2011-05-19 00:00:00

abstract：:Differences in selection pressure in nature and labs have profound effects on zebrafish strains. The widely used AB strain of zebrafish has been domesticated over several decades. Recently, there has been an upsurge in the availability of genetically modified lines, e.g., the spiegeldanio (spd), which has a mutation i...

journal_title：Frontiers in behavioral neuroscience

authors： Mustafa A,Roman E,Winberg S

更新日期：2019-11-19 00:00:00

abstract：:The increased understanding that neuropathology begins decades before symptom onset, has led to the conceptualization and widespread utilization of Mild Cognitive Impairment (MCI) as an important transitional state between healthy aging and dementia. Further subcategorization to MCI subtype has led to more distinct pr...

journal_title：Frontiers in behavioral neuroscience

authors： Broadhouse KM,Mowszowski L,Duffy S,Leung I,Cross N,Valenzuela MJ,Naismith SL

更新日期：2019-11-21 00:00:00

abstract：:Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), as co-adjuvant to enhance the effects of environmental enrichment (EE) in Ts65Dn mice, a segmenta...

journal_title：Frontiers in behavioral neuroscience

authors： Catuara-Solarz S,Espinosa-Carrasco J,Erb I,Langohr K,Notredame C,Gonzalez JR,Dierssen M

更新日期：2015-12-11 00:00:00

abstract：:The endocannabinoid (eCB) system possesses neuromodulatory functions by influencing the release of various neurotransmitters, including γ-aminobutyric acid (GABA) and glutamate. A functional interaction between eCBs and the serotonergic system has already been suggested. Previously, we showed that cannabinoid type-1 (...

journal_title：Frontiers in behavioral neuroscience

authors： Häring M,Enk V,Aparisi Rey A,Loch S,Ruiz de Azua I,Weber T,Bartsch D,Monory K,Lutz B

更新日期：2015-09-03 00:00:00

abstract：:PAOPA, a potent analog of prolyl-leucyl-glycinamide, has shown therapeutic potential at the preclinical stage for dopaminergic related illnesses, including animal models of schizophrenia, Parkinson's disease and haloperidol-induced extrapyramidal movement disorders. PAOPA's unique allosteric mechanism and dopamine D2 ...

journal_title：Frontiers in behavioral neuroscience

authors： Daya RP,Bhandari J,Kooner SK,Ho J,Rowley CD,Bock NA,Farncombe T,Mishra RK

更新日期：2018-12-12 00:00:00

abstract：:Epilepsy is a chronic neurological disease which is usually associated with psychiatric comorbidities. Depsression and cognition impairment are considered to be the most common psychiatric comorbidities in epilepsy patients. However, the specific contribution of epilepsy made to these psychiatric comorbidities remains...

journal_title：Frontiers in behavioral neuroscience

authors： Zhu X,Dong J,Han B,Huang R,Zhang A,Xia Z,Chang H,Chao J,Yao H

更新日期：2017-10-18 00:00:00

abstract：:Identifying the biological substrates of complex neurobehavioral traits such as alcohol dependency pose a tremendous challenge given the diverse model systems and phenotypic assessments used. To address this problem we have developed a platform for integrated analysis of high-throughput or genome-wide functional genom...

journal_title：Frontiers in behavioral neuroscience

authors： Bubier JA,Wilcox TD,Jay JJ,Langston MA,Baker EJ,Chesler EJ

更新日期：2016-01-21 00:00:00