Proof of concept trial of dronabinol in obstructive sleep apnea.

abstract：:Depression is one of the most prevalent and serious mental disorders with a worldwide significant health burden. Metabolic abnormalities and disorders in patients with depression have attracted great research attention. Thirty-six metabolic biomarkers of clinical plasma metabolomics were detected by platform technolog...

journal_title：Frontiers in psychiatry

authors： Gao Y,Xu T,Zhao YX,Ling-Hu T,Liu SB,Tian JS,Qin XM

更新日期：2020-07-15 00:00:00

abstract：Background:Studies have shown that patients with major depressive disorder (MDD) exhibit elevated dysfunctional attitudes (DAs). However, it remains controversial whether the DAs are state-dependent or trait-like features of MDD. Methods:This study recruited 172 patients and 159 healthy controls (HCs) at baseline. DAs...

journal_title：Frontiers in psychiatry

authors： Liu B,Sun J,Qin X,Wang M,Lu X,Dong Q,Zhang L,Liu J,Ju Y,Wan P,Guo H,Zhao F,Zhang Y,Li L

更新日期：2020-07-10 00:00:00

abstract：Background:Depression is pervasive in the military context and is likely to elicit lasting negative effects on health. Based on interpersonal models, social-interpersonal stressors are significantly associated with the development and maintenance of depression. However, little is known about the mechanisms by which the...

journal_title：Frontiers in psychiatry

authors： Wang J,Cheng X,Xu K,Xu H,Wang H,Feng Z

更新日期：2020-06-18 00:00:00

abstract：Objective:To explore the attitudes and factors in seeking professional psychological help among a Chinese community-dwelling population in order to promote positive help-seeking behaviors and better utilization of mental health services. Methods:Using system and simple random sampling with Kish selection table methods...

journal_title：Frontiers in psychiatry

authors： Chen P,Liu XJ,Wang XQ,Yang BX,Ruan J,Liu Z

更新日期：2020-05-14 00:00:00

abstract：:In a group of 1066 heroin addicts, who were seeking treatment for opioid agonist treatment, we looked for differences in historical, demographic, and clinical characteristics, between patients with different levels of awareness of illness (insight). The results showed that, in the cohort studied, a majority of subject...

journal_title：Frontiers in psychiatry

authors： Maremmani AG,Rovai L,Rugani F,Pacini M,Lamanna F,Bacciardi S,Perugi G,Deltito J,Dell'osso L,Maremmani I

更新日期：2012-07-09 00:00:00

abstract：Background:Previous studies suggested bipolar disorder caused an aberrant alteration in the insular, putamen, and left superior frontal gyrus, which are the main components of the hate circuit. However, the relationship between the hate circuit and the pathophysiologic substrate underlying different phases of bipolar d...

journal_title：Frontiers in psychiatry

authors： Fan Z,Yang J,Zeng C,Xi C,Wu G,Guo S,Xue Z,Liu Z,Tao H

更新日期：2020-10-27 00:00:00

abstract：:Recent evidence suggests that epigenetic mechanisms play a role in psychiatric diseases. In this study, we considered rats with neonatal ventral hippocampal lesions (NVHL) that are currently used for modeling neurodevelopmental aspects of schizophrenia. Contribution of epigenetic regulation to the effects of the lesio...

journal_title：Frontiers in psychiatry

authors： Sandner G,Host L,Angst MJ,Guiberteau T,Guignard B,Zwiller J

更新日期：2011-01-07 00:00:00

abstract：:Background: Job burnout has become an increasing prevailing phenomenon among nurses in both developed and developing countries. There is a paucity of research exploring the relationship between perceived stress (i.e., the level of one's perception or appraisal of stress rather than objective stressful events) and job ...

journal_title：Frontiers in psychiatry

authors： Song Y,Yang F,Sznajder K,Yang X

更新日期：2020-11-13 00:00:00

abstract：Objective:Employment was associated with recovery in individuals with schizophrenia. Our study aimed to delineate the vocational profile and investigate factors associated with likelihood of employment in individuals with schizophrenia. Materials and Methods:276 community dwelling outpatients with schizophrenia were r...

journal_title：Frontiers in psychiatry

authors： Ang MS,Rekhi G,Lee J

更新日期：2020-08-27 00:00:00

abstract：:Introduction: Antipsychotic treatment can improve the symptoms of schizophrenia; however, residual symptoms after antipsychotic treatment are frequent. The effects of exercise on the symptoms of schizophrenic patients under antipsychotic treatment are inconclusive. The aim of this randomized case-control study was to ...

journal_title：Frontiers in psychiatry

authors： Wang PW,Lin HC,Su CY,Chen MD,Lin KC,Ko CH,Yen CF

更新日期：2018-05-15 00:00:00

abstract：:Co-design, defined as collective creativity across the entire design process, can lead to the development of interventions that are more engaging, satisfying, and useful to potential users. However, using this methodology within the research arena requires a shift from traditional practice. Co-design of eHealth interv...

journal_title：Frontiers in psychiatry

authors： Thabrew H,Fleming T,Hetrick S,Merry S

更新日期：2018-10-18 00:00:00

abstract：:Despite being a commonly used protocol to treat major depressive disorder (MDD), the underlying mechanism of repetitive transcranial magnetic stimulation (rTMS) on dorsolateral prefrontal cortex (DLPFC) remains unclear. In the current study, we investigated the resting-state fMRI data of 100 healthy subjects by explor...

journal_title：Frontiers in psychiatry

authors： Ishida T,Dierks T,Strik W,Morishima Y

更新日期：2020-08-20 00:00:00

abstract：:Autism spectrum disorder (ASD) and schizophrenia (SZ) are heterogenous neurodevelopmental disorders that overlap in symptom presentation. The purpose of this study was to specify overlapping symptom domains and to identify symptoms that can reliably differentiate adults with ASD (n = 53), SZ (n = 39), and typical deve...

journal_title：Frontiers in psychiatry

authors： Trevisan DA,Foss-Feig JH,Naples AJ,Srihari V,Anticevic A,McPartland JC

更新日期：2020-06-11 00:00:00

abstract：:Background: Anorexia nervosa (AN) is a psychiatric illness that without early effective treatment becomes chronic with high physical, psychological and social morbidity and high mortality. Pilates exercises can improve quality of life and increase body awareness in different clinical and healthy populations. The aim o...

journal_title：Frontiers in psychiatry

authors： Martínez-Sánchez SM,Martínez-García C,Martínez-García TE,Munguía-Izquierdo D

更新日期：2020-10-30 00:00:00

abstract：:The human gut microbiome is emerging as a key modulator of homeostasis, with far-reaching implications for various multifactorial diseases, including anorexia nervosa (AN). Despite significant morbidity and mortality, the underlying mechanisms of this eating disorder are poorly understood, but the classical view defin...

journal_title：Frontiers in psychiatry

authors： Ghenciulescu A,Park RJ,Burnet PWJ

更新日期：2021-01-12 00:00:00

abstract：:Background: People with severe mental disorders (SMDs) have higher disease and death rates than the general population. Stigma (negative attitudes and perceptions) contributes to limited access to health services and a lower quality of medical assistance in this population, and it is manifested as negative attitudes, ...

journal_title：Frontiers in psychiatry

authors： Grandón P,Saldivia S,Vaccari P,Ramirez-Vielma R,Victoriano V,Zambrano C,Ortiz C,Cova F

更新日期：2019-03-07 00:00:00

abstract：:In the brain of female mammals, including humans, a number of physiological and behavioral changes occur as a result of sex hormone exposure. Estradiol and progesterone regulate several brain functions, including learning and memory. Sex hormones contribute to shape the central nervous system by modulating the formati...

journal_title：Frontiers in psychiatry

authors： Hansberg-Pastor V,González-Arenas A,Piña-Medina AG,Camacho-Arroyo I

更新日期：2015-11-20 00:00:00

abstract：:The impact of COVID-19 on the elderly is devastating, and nursing homes are struggling to provide the best care to the most fragile. The urgency and severity of the pandemic forces the use of segregation in restricted areas and confinement in individual rooms as desperate strategies to avoid the spread of disease and ...

journal_title：Frontiers in psychiatry

authors： Muntsant A,Giménez-Llort L

更新日期：2020-11-24 00:00:00

abstract：Objectives:The modified Yale Food Addiction Scale 2.0 (mYFAS 2.0) was designed to assess food addiction using a shorter version than the YFAS 2.0. We lack data about the psychometric properties of the mYFAS 2.0 in patients with obesity, as well as studies comparing the psychometric properties of the mYFAS 2.0 versus th...

journal_title：Frontiers in psychiatry

authors： Brunault P,Berthoz S,Gearhardt AN,Gierski F,Kaladjian A,Bertin E,Tchernof A,Biertho L,de Luca A,Hankard R,Courtois R,Ballon N,Benzerouk F,Bégin C

更新日期：2020-09-08 00:00:00

abstract：:Background: Mental disorders are highly prevalent among university students. Distance-learning students are particularly burdened and have limited access to conventional university health services. Interventions for stress are sought after in distance learners and may help increase treatment coverage. Internet-based i...

journal_title：Frontiers in psychiatry

authors： Harrer M,Apolinário-Hagen J,Fritsche L,Drüge M,Krings L,Beck K,Salewski C,Zarski AC,Lehr D,Baumeister H,Ebert DD

更新日期：2019-05-21 00:00:00

abstract：:According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated with the positive and negative symptoms of schizophrenia. However, the underlying mechanisms responsible for the changes in glutamate transmission ...

journal_title：Frontiers in psychiatry

authors： Mei YY,Wu DC,Zhou N

更新日期：2018-11-06 00:00:00

abstract：:Eating disorders (EDs) are serious psychopathologies characterized by a persistent disturbance in eating or eating-related behavior. Studies have shown EDs' detrimental consequences not only for patients, but also for their families. Nevertheless, a specific group that has so far been neglected, in both the research a...

journal_title：Frontiers in psychiatry

authors： Maon I,Horesh D,Gvion Y

更新日期：2020-06-30 00:00:00

abstract：:Background: There is a trade-off between drug-related impulsive process and cognitive reflective process among ex-drug abusers. The present study aimed to investigate the impulsive effects of methamphetamine-related stimuli on working memory (WM) performance by manipulating WM load in abstinent ex-methamphetamine user...

journal_title：Frontiers in psychiatry

authors： Deldar Z,Ekhtiari H,Pouretemad HR,Khatibi A

更新日期：2019-10-22 00:00:00

abstract：:Background: The Maslach Burnout Inventory-Human Services Survey (MBI-HSS) is the most commonly used instrument to assess burnout. Although various factors have been reported to influence its validity, the influence of major depressive disorder (MDD) has not been previously considered. We developed this study to invest...

journal_title：Frontiers in psychiatry

authors： Trigo TR,de Freitas CCS,Wang YP,Ribeiro FG,de Lucia MCS,Siqueira JO,Iosifescu DV,Hallak JEC,Fraguas R

更新日期：2018-12-18 00:00:00

abstract：Objectives:Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understandin...

journal_title：Frontiers in psychiatry

authors： Smirnova D,Cumming P,Sloeva E,Kuvshinova N,Romanov D,Nosachev G

更新日期：2018-04-10 00:00:00

abstract：:Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...

journal_title：Frontiers in psychiatry

authors： Corbit LH,Janak PH

更新日期：2016-10-10 00:00:00

abstract：:The present study aims to analyze the clinical and socio-demographic characteristics of patients with obsessive-compulsive disorder (OCD) in comorbidity with schizotypal personality disorder (SPD), as well as the response rate to pharmacological treatments. OCD+SPD patients had a younger age at onset, a higher probabi...

journal_title：Frontiers in psychiatry

authors： Perris F,Fabrazzo M,De Santis V,Luciano M,Sampogna G,Fiorillo A,Catapano F

更新日期：2019-06-17 00:00:00

abstract：:The extraordinary health emergency of the COVID-19 pandemic represents a new challenge for mental health researchers and clinical practitioners. The related containment measures may be a risk factor for psychological distress and mood disorders, especially in at-risk populations. This study aims to explore the impact ...

journal_title：Frontiers in psychiatry

authors： Spinola O,Liotti M,Speranza AM,Tambelli R

更新日期：2020-11-17 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance cognitive control functions including attention and top-down regulation over negative affect and substance craving in both healthy and clinical populations, including early abstinent (∼1.5 h) smokers. The aim of this study was to assess whether tDCS modulates ...

journal_title：Frontiers in psychiatry

authors： Xu J,Fregni F,Brody AL,Rahman AS

更新日期：2013-09-20 00:00:00

abstract：:Background: The outbreak of COVID-19 in China was a sudden bio-disaster, which may bring a negative impact on the job burnout of health care professionals (HCPs). Objective: We aim to find out the association factors, especially those closely related to this outbreak, of job burnout in Chinese HCPs. Method: The cross-...

journal_title：Frontiers in psychiatry

authors： Liu X,Chen J,Wang D,Li X,Wang E,Jin Y,Ma Y,Yu C,Luo C,Zhang L,Liu C,Zhou Y,Yang L,Song J,Bai T,Hou X

更新日期：2020-12-08 00:00:00