Treatment of enterohemorrhagic Escherichia coli (EHEC) infection and hemolytic uremic syndrome (HUS).

abstract：BACKGROUND:During the past decades, life expectancy has continued to increase in most high-income countries. Previous research suggests that improvements in life expectancy have primarily been driven by advances at the upper end of the health distribution, while parts of the population have lagged behind. Using data fr...

journal_title：BMC medicine

authors： Meyer AC,Drefahl S,Ahlbom A,Lambe M,Modig K

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND:Network meta-analyses using individual participant data (IPD-NMAs) have been increasingly used to compare the effects of multiple interventions. Although there have been many studies on statistical methods for IPD-NMAs, it is unclear whether there are statistical defects in published IPD-NMAs and whether the...

journal_title：BMC medicine

authors： Gao Y,Shi S,Li M,Luo X,Liu M,Yang K,Zhang J,Song F,Tian J

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The rapidly increasing number of activity-induced musculoskeletal injuries among adolescents and young adults is currently a true public health burden. The objective of this study was to investigate whether a neuromuscular training programme with injury prevention counselling is effective in preventing acute...

journal_title：BMC medicine

authors： Parkkari J,Taanila H,Suni J,Mattila VM,Ohrankämmen O,Vuorinen P,Kannus P,Pihlajamäki H

更新日期：2011-04-11 00:00:00

abstract：BACKGROUND:Populations exposed to humanitarian emergencies are particularly vulnerable to mental health problems, including new onset, relapse and deterioration of psychotic disorders. Inadequate care for this group may lead to human rights abuses and even premature death. The WHO Mental Health Gap Action Programme Int...

journal_title：BMC medicine

authors： Ostuzzi G,Barbui C,Hanlon C,Chatterjee S,Eaton J,Jones L,Silove D,Ventevogel P

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:In July 2014, an outbreak of Ebola virus disease (EVD) started in Pujehun district, Sierra Leone. On January 10th, 2015, the district was the first to be declared Ebola-free by local authorities after 49 cases and a case fatality rate of 85.7%. The Pujehun outbreak represents a precious opportunity for impro...

journal_title：BMC medicine

authors： Ajelli M,Parlamento S,Bome D,Kebbi A,Atzori A,Frasson C,Putoto G,Carraro D,Merler S

更新日期：2015-11-26 00:00:00

abstract：BACKGROUND:Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic myelopathy characterized by motor dysfunction of the lower extremities and urinary disturbance. Immunomodulatory treatments are the main strategy for HAM/TSP, but several issues are associated...

journal_title：BMC medicine

authors： Nakamura T,Matsuo T,Fukuda T,Yamato S,Yamaguchi K,Kinoshita I,Matsuzaki T,Nishiura Y,Nagasato K,Narita-Masuda T,Nakamura H,Satoh K,Sasaki H,Sakai H,Kawakami A

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Predicting treatment benefit and/or outcome before any therapeutic intervention has taken place would be clinically very useful. Herein, we evaluate the ability of the intrinsic subtypes and the risk of relapse score at diagnosis to predict survival and response following neoadjuvant chemotherapy. In additio...

journal_title：BMC medicine

authors： Prat A,Fan C,Fernández A,Hoadley KA,Martinello R,Vidal M,Viladot M,Pineda E,Arance A,Muñoz M,Paré L,Cheang MC,Adamo B,Perou CM

更新日期：2015-12-18 00:00:00

abstract：BACKGROUND:Mathematical and computational models for infectious diseases are increasingly used to support public-health decisions; however, their reliability is currently under debate. Real-time forecasts of epidemic spread using data-driven models have been hindered by the technical challenges posed by parameter estim...

journal_title：BMC medicine

authors： Tizzoni M,Bajardi P,Poletto C,Ramasco JJ,Balcan D,Gonçalves B,Perra N,Colizza V,Vespignani A

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and incident depression using repeated measurements of alcohol intake. METHODS:We followed-up 5,505 h...

journal_title：BMC medicine

authors： Gea A,Beunza JJ,Estruch R,Sánchez-Villegas A,Salas-Salvadó J,Buil-Cosiales P,Gómez-Gracia E,Covas MI,Corella D,Fiol M,Arós F,Lapetra J,Lamuela-Raventós RM,Wärnberg J,Pintó X,Serra-Majem L,Martínez-González MA,PREDIMED G

更新日期：2013-08-30 00:00:00

abstract：BACKGROUND:Tumor necrosis factor (TNF)-α inhibitors are increasingly being used in inflammatory bowel disease (IBD). Because this chronic intestinal disorder often affects women of fertile age, it is essential to assess the effect of biologics on pregnancy outcome. METHODS:We performed a systematic review of the Engli...

journal_title：BMC medicine

authors： Nielsen OH,Loftus EV Jr,Jess T

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Vertical and horizontal trust, as dimensions of social capital, may be important determinants of health. As mass media campaigns have been used extensively to promote healthy lifestyles and convey health-related information, high levels of individual trust in the media may facilitate the success of such camp...

journal_title：BMC medicine

authors： Tokuda Y,Fujii S,Jimba M,Inoguchi T

更新日期：2009-01-22 00:00:00

abstract：:Although imatinib is firmly established as an effective therapy for newly diagnosed patients with chronic myeloid leukemia (CML), the field continues to advance on several fronts. In this minireview we cover recent results of second generation tyrosine kinase inhibitors in newly diagnosed patients, investigate the sta...

journal_title：BMC medicine

authors： Eiring AM,Khorashad JS,Morley K,Deininger MW

更新日期：2011-08-26 00:00:00

abstract：BACKGROUND:The United Nation's Sustainable Development Goals for 2030 include reducing premature mortality from non-communicable diseases (NCDs) by one third. To assess the feasibility of this goal in China, we projected premature mortality in 2030 of NCDs under different risk factor reduction scenarios. METHODS:We us...

journal_title：BMC medicine

authors： Li Y,Zeng X,Liu J,Liu Y,Liu S,Yin P,Qi J,Zhao Z,Yu S,Hu Y,He G,Lopez AD,Gao GF,Wang L,Zhou M

更新日期：2017-07-11 00:00:00

abstract：BACKGROUND:Although a number of risk factors are known to predict mortality within the first years after myocardial infarction, little is known about interactions between risk factors, whereas these could contribute to accurate differentiation of patients with higher and lower risk for mortality. This study explored th...

journal_title：BMC medicine

authors： van Loo HM,van den Heuvel ER,Schoevers RA,Anselmino M,Carney RM,Denollet J,Doyle F,Freedland KE,Grace SL,Hosseini SH,Parakh K,Pilote L,Rafanelli C,Roest AM,Sato H,Steeds RP,Kessler RC,de Jonge P

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:In recent years, medical practice has followed two different paradigms: evidence-based medicine (EBM) and values-based medicine (VBM). There is an urgent need to promote medical education that strengthens the relationship between these two paradigms. This work is designed to establish the foundations for a c...

journal_title：BMC medicine

authors： Altamirano-Bustamante MM,Altamirano-Bustamante NF,Lifshitz A,Mora-Magaña I,de Hoyos A,Avila-Osorio MT,Quintana-Vargas S,Aguirre JA,Méndez J,Murata C,Nava-Diosdado R,Martínez-González O,Calleja E,Vargas R,Mejía-Arangure JM,C

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Managing hearing communication for residents living with hearing loss and dementia in long-term care settings is challenging. This paper explores how care can be effective in optimising hearing communication for residents living with dementia. We argue that the underlying notion of permission or authorisatio...

journal_title：BMC medicine

authors： Crosbie B,Ferguson M,Wong G,Walker DM,Vanhegan S,Dening T

更新日期：2019-03-04 00:00:00

abstract：BACKGROUND:The consumption of free sugars in the UK is more than double the guideline intake for adults and close to triple for children, with soft drinks representing a significant proportion. The aim of this study was to assess how individual soft drink companies and consumers have responded to calls to reduce sugar ...

journal_title：BMC medicine

authors： Bandy LK,Scarborough P,Harrington RA,Rayner M,Jebb SA

更新日期：2020-01-13 00:00:00

abstract：:A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10 years, key milestones have moved celiac disease from obscurity into the popular spotlight worldwide. Now we are observing another interesting phenomenon that i...

journal_title：BMC medicine

authors： Sapone A,Bai JC,Ciacci C,Dolinsek J,Green PH,Hadjivassiliou M,Kaukinen K,Rostami K,Sanders DS,Schumann M,Ullrich R,Villalta D,Volta U,Catassi C,Fasano A

更新日期：2012-02-07 00:00:00

abstract：:This comment relates to articles published in archived content of the journal Head and Neck Oncology and is not related to the content of BMC Medicine in any way. ...

journal_title：BMC medicine

authors： BioMed Central.

更新日期：2014-02-05 00:00:00

abstract：BACKGROUND:Clinical decision support systems assist physicians in interpreting complex patient data. However, they typically operate on a per-patient basis and do not exploit the extensive latent medical knowledge in electronic health records (EHRs). The emergence of large EHR systems offers the opportunity to integrat...

journal_title：BMC medicine

authors： Gottlieb A,Stein GY,Ruppin E,Altman RB,Sharan R

更新日期：2013-09-02 00:00:00

abstract：BACKGROUND:Vaccination has reduced the global incidence of measles to the lowest rates in history. However, local interruption of measles virus transmission requires sustained high levels of population immunity that can be challenging to achieve and maintain. The herd immunity threshold for measles is typically stipula...

journal_title：BMC medicine

authors： Funk S,Knapp JK,Lebo E,Reef SE,Dabbagh AJ,Kretsinger K,Jit M,Edmunds WJ,Strebel PM

更新日期：2019-09-25 00:00:00

abstract：BACKGROUND:Alcohol consumption is a leading contributor to death and disability worldwide, but previous research has not examined the effects of different patterns of alcohol consumption. The study objective was to understand the relationship between different alcohol consumption patterns and adverse health outcomes ri...

journal_title：BMC medicine

authors： Jani BD,McQueenie R,Nicholl BI,Field R,Hanlon P,Gallacher KI,Mair FS,Lewsey J

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:In patients with stage II colorectal cancer (CRC) the number of surgically retrieved lymph nodes (LNs) is associated with prognosis, resulting in a minimum of 10-12 retrieved LNs being recommended for this stage. Current guidelines do not provide a recommendation regarding LN yield in T1 CRC. Studies evaluat...

journal_title：BMC medicine

authors： Backes Y,Elias SG,Bhoelan BS,Groen JN,van Bergeijk J,Seerden TCJ,Pullens HJM,Spanier BWM,Geesing JMJ,Kessels K,Kerkhof M,Siersema PD,de Vos Tot Nederveen Cappel WH,van Lelyveld N,Wolfhagen FHJ,Ter Borg F,Offerhaus GJA,L

更新日期：2017-07-14 00:00:00

abstract：:In the past decade, numerous studies have made connections between sequence variants in human genomes and predisposition to complex diseases. However, most of these variants lie outside of the charted regions of the human genome whose function we understand; that is, the sequences that encode proteins. Consequently, t...

journal_title：BMC medicine

authors： St Laurent G,Vyatkin Y,Kapranov P

更新日期：2014-06-12 00:00:00

abstract：BACKGROUND:The 'Older People's Exercise intervention in Residential and nursing Accommodation' (OPERA) cluster randomised trial evaluated the impact of training for care home staff together with twice-weekly, physiotherapist-led exercise classes on depressive symptoms in care home residents, but found no effect. We rep...

journal_title：BMC medicine

authors： Ellard DR,Thorogood M,Underwood M,Seale C,Taylor SJ

更新日期：2014-01-03 00:00:00

abstract：:Due to the easier access to information, the availability of low cost technologies and the involvement of well educated, passionate patients, a group of citizen 'Health Hackers', who are building their own medical systems to help them overcome the unmet needs of their conditions, is emerging. This has recently been th...

journal_title：BMC medicine

authors： Omer T

更新日期：2016-08-17 00:00:00

abstract：BACKGROUND:In an era when obesity prevalence is high throughout much of the world, there is a correspondingly pervasive and strong culture of weight stigma. For example, representative studies show that some forms of weight discrimination are more prevalent even than discrimination based on race or ethnicity. DISCUSSI...

journal_title：BMC medicine

authors： Tomiyama AJ,Carr D,Granberg EM,Major B,Robinson E,Sutin AR,Brewis A

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:Cognitive impairment is very common in late-life depression, principally affecting executive skills and information processing speed. The aim of the study was to examine the effect of antidepressant treatment on cognitive performances over a 10-year period. METHODS:The community-based cohort included 7381 p...

journal_title：BMC medicine

authors： Carrière I,Norton J,Farré A,Wyart M,Tzourio C,Noize P,Pérès K,Fourrier-Réglat A,Ritchie K,Ancelin ML

更新日期：2017-04-19 00:00:00

abstract：BACKGROUND:The placebo response in patients with diabetes mellitus is very common. A systematic evaluation needs to be updated with the current evidence about the placebo response in diabetes mellitus and the associated factors in clinical trials of anti-diabetic medicine. METHODS:Literature research was conducted in ...

journal_title：BMC medicine

authors： Lin C,Cai X,Yang W,Lv F,Nie L,Ji L

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Use of fenfluramines for weight loss has been associated with the development of characteristic plaques on cardiac valves causing regurgitation. However, previously published studies of exposure to fenfluramines have been limited by relatively small sample size, short duration of follow-up, and the lack of a...

journal_title：BMC medicine

authors： Dahl CF,Allen MR,Urie PM,Hopkins PN

更新日期：2008-11-06 00:00:00