Lobeline for smoking cessation.

Abstract:

BACKGROUND:Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES:The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH STRATEGY:We searched the Cochrane Tobacco Addiction Group trials register. SELECTION CRITERIA:Randomized trials comparing lobeline to placebo or an alternative therapeutic control, which reported smoking cessation with at least six months follow-up. DATA COLLECTION AND ANALYSIS:We extracted data in duplicate on the type of subjects, the dose and form of lobeline, the outcome measures, method of randomisation, and completeness of follow-up. MAIN RESULTS:We identified no trials meeting the full inclusion criteria including long term follow-up. REVIEWER'S CONCLUSIONS:There is no evidence available from long term trials that lobeline can aid smoking cessation.

authors

Stead LF,Hughes JR

doi

10.1002/14651858.CD000124

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

CD000124

issue

2

issn

1469-493X

pii

CD000124

pub_type

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