Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.

Abstract:

BACKGROUND:Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis. CASE REPORT:We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes. CONCLUSIONS:Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

journal_name

Med Sci Monit

authors

Brydak-Godowska J,Szczepanik S,Ciszek M,Bialas D,Grzeszczyk M,Strzeleck D,Kecik D

doi

10.12659/msm.881890

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

CS99-102

issue

8

eissn

1234-1010

issn

1643-3750

pii

881890

journal_volume

17

pub_type

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