Decoding continuous variables from neuroimaging data: basic and clinical applications.

abstract：:Previous works exploring the challenges of ensuring information security for neuroprosthetic devices and their users have typically built on the traditional InfoSec concept of the "CIA Triad" of confidentiality, integrity, and availability. However, we argue that the CIA Triad provides an increasingly inadequate found...

journal_title：Frontiers in neuroscience

authors： Gladden ME

更新日期：2017-11-07 00:00:00

abstract：:The diterpenoid compound, Oridonin, extracted from the Chinese herb, Rabdosia rubescens, possesses multiple biological activities and properties. Oridonin exhibited efficient anti-inflammatory activity by inducing a switch in macrophage polarization to the anti-inflammatory phenotype through inhibition of the Notch pa...

journal_title：Frontiers in neuroscience

authors： Xu L,Li L,Zhang CY,Schluesener H,Zhang ZY

更新日期：2019-04-02 00:00:00

abstract：:Evidence is mounting that LRRK2 function, particularly its kinase activity, is elevated in multiple forms of Parkinson's disease, both idiopathic as well as familial forms linked to mutations in the LRRK2 gene. However, sensitive quantitative markers of LRRK2 activation in clinical samples remain at the early stages o...

journal_title：Frontiers in neuroscience

authors： Rideout HJ,Chartier-Harlin MC,Fell MJ,Hirst WD,Huntwork-Rodriguez S,Leyns CEG,Mabrouk OS,Taymans JM

更新日期：2020-08-18 00:00:00

abstract：:The GABAergic neurons in the lateral pontine tegmentum (LPT) play key roles in the regulation of sleep and locomotion. The dysfunction of the LPT is related to neurological disorders such as rapid eye movement sleep behavior disorder and ocular flutter. However, the whole-brain neural connectivity to LPT GABAergic neu...

journal_title：Frontiers in neuroscience

authors： Chen ZK,Yuan XS,Dong H,Wu YF,Chen GH,He M,Qu WM,Huang ZL

更新日期：2019-04-24 00:00:00

abstract：:The default mode network (DMN) has been used to study disruptions of functional connectivity in a wide variety of psychiatric and neurological conditions, including posttraumatic stress disorder (PTSD). Studies indicate that the serotonin system exerts a modulatory influence on DMN connectivity; however, no prior stud...

journal_title：Frontiers in neuroscience

authors： Miller MW,Sperbeck E,Robinson ME,Sadeh N,Wolf EJ,Hayes JP,Logue M,Schichman SA,Stone A,Milberg W,McGlinchey R

更新日期：2016-06-28 00:00:00

abstract：:In our complex acoustic environment, we are confronted with a mixture of sounds produced by several simultaneous sources. However, we rarely perceive these sounds as incomprehensible noise. Our brain uses perceptual organization processes to independently follow the emission of each sound source over time. If the acou...

journal_title：Frontiers in neuroscience

authors： Bidet-Caulet A,Bertrand O

更新日期：2009-09-15 00:00:00

abstract：:Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders entailing social and cognitive deficits, including marked problems with language. Numerous genes have been associated with ASD, but it is unclear how language deficits arise from gene mutation or dysregulation. It is also unclear why ASD shows ...

journal_title：Frontiers in neuroscience

authors： Benítez-Burraco A,Lattanzi W,Murphy E

更新日期：2016-08-29 00:00:00

abstract：:The resting activity of the brain can be described by so-called intrinsic connectivity networks (ICNs), which consist of spatially and temporally distributed, but functionally connected, nodes. The coordinated activity of the resting state can be explored via magnetoencephalography (MEG) by studying frequency-dependen...

journal_title：Frontiers in neuroscience

authors： Dimitriadis SI,Routley B,Linden DE,Singh KD

更新日期：2018-08-03 00:00:00

abstract：:In adult mammals, neural stem cells (NSCs) are found in two niches of the brain; the subventricular zone by the lateral ventricles and the subgranular zone of the dentate gyrus in the hippocampus. Neurogenesis is a complex process that is tightly controlled on a molecular level. Recently, microRNAs (miRNAs) have been ...

journal_title：Frontiers in neuroscience

authors： Akerblom M,Sachdeva R,Jakobsson J

更新日期：2012-02-07 00:00:00

abstract：:Background: Stroke is the second leading cause of death worldwide. Angiogenesis facilitates the formation of microvascular networks and promotes recovery after stroke. The Shh/Gli signaling pathway is implicated in angiogenesis and cerebral ischemia-reperfusion (I/R) injury. This study aimed at investigating the influ...

journal_title：Frontiers in neuroscience

authors： Peng L,Yin J,Ge M,Wang S,Xie L,Li Y,Si JQ,Ma K

更新日期：2019-04-09 00:00:00

abstract：:The combination of electromyography (EMG) and transcranial magnetic stimulation (TMS) offers a powerful non-invasive approach for investigating corticospinal excitability in both humans and animals. Acquiring and analyzing the data produced with this combination of tools requires overcoming multiple technical hurdles....

journal_title：Frontiers in neuroscience

authors： Jackson N,Greenhouse I

更新日期：2019-09-13 00:00:00

abstract：:The utility of premovement electroencephalography (EEG) for decoding movement intention during a reaching task has been demonstrated. However, the kind of information the brain represents regarding the intended target during movement preparation remains unknown. In the present study, we investigated which movement par...

journal_title：Frontiers in neuroscience

authors： Kim H,Yoshimura N,Koike Y

更新日期：2019-11-01 00:00:00

abstract：:The melanocortin receptors (MCRs) are a gene family in the rhodopsin class of G protein-coupled receptors. Based on the analysis of several metazoan genome databases it appears that the MCRs are only found in chordates. The presence of five genes in the family (i.e., mc1r, mc2r, mc3r, mc4r, mc5r) in representatives of...

journal_title：Frontiers in neuroscience

authors： Dores RM

更新日期：2013-04-10 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) has been shown to affect motor and cognitive task performance and learning when applied to brain areas involved in the task. Targeted stimulation has also been found to alter connectivity within the stimulated hemisphere during rest. However, the connectivity effect of th...

journal_title：Frontiers in neuroscience

authors： Baxter BS,Edelman BJ,Sohrabpour A,He B

更新日期：2017-12-07 00:00:00

abstract：:People generally prefer risky options, which have fully specified outcome probabilities, to ambiguous options, which have unspecified probabilities. This preference, formalized in economics, is strong enough that people will reliably prefer a risky option to an ambiguous option with a greater expected value. Explanati...

journal_title：Frontiers in neuroscience

authors： Hayden BY,Heilbronner SR,Platt ML

更新日期：2010-09-17 00:00:00

abstract：:Alzheimer's disease (AD), a chronic multifactorial and complex neurodegenerative disorder is a leading cause of dementia. Recently, neuroinflammation has been hypothesized as a contributing factor to AD pathogenesis. The role of adaptive immune responses against neuronal antigens, which can either confer protection or...

journal_title：Frontiers in neuroscience

authors： Dhanwani R,Pham J,Premlal ALR,Frazier A,Kumar A,Pero ME,Bartolini F,Dutra JR,Marder KS,Peters B,Sulzer D,Sette A,Lindestam Arlehamn CS

更新日期：2020-08-27 00:00:00

abstract：:Probability and risk are important factors for value-based decision making and optimal foraging. In order to survive in an unpredictable world, organisms must be able to assess the probability and risk attached to future events and use this information to generate adaptive behavior. Recent studies in non-human primate...

journal_title：Frontiers in neuroscience

authors： Burke CJ,Tobler PN

更新日期：2011-10-11 00:00:00

abstract：:The Embden-Meyerhof-Parnas (EMP) pathway comprises eleven cytosolic enzymes interacting to metabolize glucose to lactic acid [CH3CH(OH)COOH]. Glycolysis is largely considered as the conversion of glucose to pyruvate (CH3COCOO-). We consider glycolysis to be a cellular process and as such, transporters mediating glucos...

journal_title：Frontiers in neuroscience

authors： Roosterman D,Meyerhof W,Cottrell GS

更新日期：2018-06-15 00:00:00

abstract：:Although flight is regarded as a key behavior of birds this review argues that the perceptual demands for its control are met within constraints set by the perceptual demands of two other key tasks: the control of bill (or feet) position, and the detection of food items/predators. Control of bill position, or of the f...

journal_title：Frontiers in neuroscience

authors： Martin GR

更新日期：2017-11-07 00:00:00

abstract：:The detection of mild cognitive impairment (MCI), the transitional stage between normal cognitive changes of aging and the cognitive decline caused by AD, is of paramount clinical importance, since MCI patients are at increased risk of progressing into AD. Electroencephalographic (EEG) alterations in the spectral cont...

journal_title：Frontiers in neuroscience

authors： Dimitriadis SI,Laskaris NA,Bitzidou MP,Tarnanas I,Tsolaki MN

更新日期：2015-10-20 00:00:00

abstract：:Decoding laminar information across deep brain structures and cortical regions is necessary in order to understand the neuronal ensembles that represent cognition and memory. Large animal models are essential for translational research due to their gyrencephalic neuroanatomy and significant white matter composition. A...

journal_title：Frontiers in neuroscience

authors： Ulyanova AV,Cottone C,Adam CD,Gagnon KG,Cullen DK,Holtzman T,Jamieson BG,Koch PF,Chen HI,Johnson VE,Wolf JA

更新日期：2019-04-26 00:00:00

abstract：:Ischemic stroke places an increasing burden on individuals, families, and societies around the world. However, effective therapies or drugs for ischemic stroke are lacking. Therefore, animal models mimicking ischemic stroke in humans are of great value for preclinical experiments. middle cerebral artery occlusion (MCA...

journal_title：Frontiers in neuroscience

authors： Shi XF,Ai H,Lu W,Cai F

更新日期：2019-02-12 00:00:00

abstract：:Neuromorphic systems are gaining increasing importance in an era where CMOS digital computing techniques are reaching physical limits. These silicon systems mimic extremely energy efficient neural computing structures, potentially both for solving engineering applications as well as understanding neural computation. T...

journal_title：Frontiers in neuroscience

authors： Hasler J,Marr B

更新日期：2013-09-10 00:00:00

abstract：:Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic lateral sclerosis, are a prominent class of neurological diseases currently without a cure. They are characterized by an inexorable loss of a specific type of neurons. The selective vulnerability of specific neuronal clusters (typi...

journal_title：Frontiers in neuroscience

authors： Muddapu VR,Dharshini SAP,Chakravarthy VS,Gromiha MM

更新日期：2020-03-31 00:00:00

abstract：:Stroke patients often use trunk to compensate for impaired upper limb motor function during upper limb rehabilitation training, which results in a reduced rehabilitation training effect. Detecting trunk compensations can improve the effect of rehabilitation training. This study investigates the feasibility of a surfac...

journal_title：Frontiers in neuroscience

authors： Ma K,Chen Y,Zhang X,Zheng H,Yu S,Cai S,Xie L

更新日期：2019-11-21 00:00:00

abstract：:Uncovering brain activity from magnetoencephalography (MEG) data requires solving an ill-posed inverse problem, greatly confounded by noise, interference, and correlated sources. Sparse reconstruction algorithms, such as Champagne, show great promise in that they provide focal brain activations robust to these confoun...

journal_title：Frontiers in neuroscience

authors： Owen JP,Sekihara K,Nagarajan SS

更新日期：2012-12-26 00:00:00

abstract：:It is known that various endocrine modulators, including leptin and ghrelin, have neuroprotective roles in neurological diseases. Leptin is a hormone produced by adipocytes and was originally identified as a gene related to obesity in mice. The leptin receptors in the hypothalamus are the main target for the homeostat...

journal_title：Frontiers in neuroscience

authors： Fujita Y,Yamashita T

更新日期：2019-08-07 00:00:00

abstract：:We asked whether coordinated voluntary movement of the lower limbs could be regained in an individual having been completely paralyzed (>4 year) and completely absent of vision (>15 year) using two novel strategies-transcutaneous electrical spinal cord stimulation at selected sites over the spine as well as pharmacolo...

journal_title：Frontiers in neuroscience

authors： Gad P,Gerasimenko Y,Zdunowski S,Turner A,Sayenko D,Lu DC,Edgerton VR

更新日期：2017-06-08 00:00:00

abstract：:Chemical communication via sex pheromones is critical for successful reproduction but the underlying neural mechanisms are not well-understood. The goldfish is a tractable model because sex pheromones have been well-characterized in this species. We used male goldfish forebrain explants in vitro and performed whole-ce...

journal_title：Frontiers in neuroscience

authors： Lado WE,Spanswick DC,Lewis JE,Trudeau VL

更新日期：2014-06-30 00:00:00

abstract：:Auditory recognition memory in non-human primates differs from recognition memory in other sensory systems. Monkeys learn the rule for visual and tactile delayed matching-to-sample within a few sessions, and then show one-trial recognition memory lasting 10-20 min. In contrast, monkeys require hundreds of sessions to ...

journal_title：Frontiers in neuroscience

authors： Muñoz-López M,Insausti R,Mohedano-Moriano A,Mishkin M,Saunders RC

更新日期：2015-05-18 00:00:00