Anhedonia and substance dependence: clinical correlates and treatment options.

Abstract:

:Anhedonia is a condition in which the capacity of experiencing pleasure is totally or partially lost, and it refers to both a state symptom in various psychiatric disorders and a personality trait. It has a putative neural substrate, originating in the dopaminergic mesolimbic and mesocortical reward circuit. Anhedonia frequently occurs in mood disorders, as a negative symptom in schizophrenia, and in substance use disorders. In particular, we focus our attention on the relationships occurring between anhedonia and substance use disorders, as highlighted by many studies. Several authors suggested that anhedonia is an important factor involved in relapse as well as in the transition from recreational use to excessive drug intake. In particular, anhedonia has been found to be a frequent feature in alcoholics and addicted patients during acute and chronic withdrawal as well as in cocaine, stimulant, and cannabis abusers. Furthermore, in subjects with a substance dependence disorder, there is a significant correlation between anhedonia, craving, intensity of withdrawal symptoms, and psychosocial and personality characteristics. Therefore treating anhedonia in detoxified alcohol-dependent subjects could be critical in terms of relapse prevention strategies, given its strong relationship with craving.

journal_name

Front Psychiatry

journal_title

Frontiers in psychiatry

authors

Hatzigiakoumis DS,Martinotti G,Giannantonio MD,Janiri L

doi

10.3389/fpsyt.2011.00010

subject

Has Abstract

pub_date

2011-03-17 00:00:00

pages

10

issn

1664-0640

journal_volume

2

pub_type

杂志文章
  • Impaired Facial Emotion Recognition in Individuals at Ultra-High Risk for Psychosis and Associations With Schizotypy and Paranoia Level.

    abstract:Background:Patients with schizophrenia and individuals at ultra-high risk for psychosis (UHR) have been reported to exhibit impaired recognition of facial emotion expressions. This impairment has involved both inaccuracy and negative bias of facial emotion recognition. The present study aimed to investigate whether UHR...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00577

    authors: Seo E,Park HY,Park K,Koo SJ,Lee SY,Min JE,Lee E,An SK

    更新日期:2020-06-26 00:00:00

  • Resilience as a Mediator Between Interpersonal Risk Factors and Hopelessness in Depression.

    abstract::Several studies investigated the role of resilience as a mediating factor for psychopathological phenotypes. The aim of the current study is to explore the putative role of resilience as a mediator between different vulnerability factors and depressive symptoms. One hundred and fifty patients with a major depressive d...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00010

    authors: Collazzoni A,Stratta P,Pacitti F,Rossi A,Santarelli V,Bustini M,Talevi D,Socci V,Rossi R

    更新日期:2020-02-28 00:00:00

  • Enhanced dopamine D1 and BDNF signaling in the adult dorsal striatum but not nucleus accumbens of prenatal cocaine treated mice.

    abstract::Previous work from our group and others utilizing animal models have demonstrated long-lasting structural and functional alterations in the meso-cortico-striatal dopamine pathway following prenatal cocaine (PCOC) treatment. We have shown that PCOC treatment results in augmented D1-induced cyclic AMP (cAMP) and cocaine...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2011.00067

    authors: Tropea TF,Kabir ZD,Kaur G,Rajadhyaksha AM,Kosofsky BE

    更新日期:2011-12-07 00:00:00

  • An Intervention to Increase Situational Awareness and the Culture of Mutual Care (Foco) and Its Effects During COVID-19 Pandemic: A Randomized Controlled Trial and Qualitative Analysis.

    abstract::Situational awareness is especially important to decision-making in health care. Comprehending the situation is crucial for anticipating any change in the environment and delivering optimal care. The objective of this study was to evaluate the effects of a training to increase situational awareness and mutual care des...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.570786

    authors: Kozasa EH,Lacerda SS,Polissici MA,Coelho RDS,Farias GDS,Chaves P,Leão ER

    更新日期:2020-11-26 00:00:00

  • Criminal Responsibility Scale: Development and Validation of a Psychometric Tool Structured in Clinical Vignettes for Criminal Responsibility Assessments in Brazil.

    abstract::Criminal responsibility assessment is undertaken by psychologists or psychiatrists to assess offenders' legal capacities, which vary among countries or regional legislations. There are two psychometric tools (i.e., checklists) validated for criminal responsibility assessment: the Roger Criminal Responsibility Scale, a...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.579243

    authors: Meyer LF,Leal CCS,Omena AAS,Mecler K,Valença AM

    更新日期:2020-11-27 00:00:00

  • Changes in the Influence of Alcohol-Paired Stimuli on Alcohol Seeking across Extended Training.

    abstract::Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2016.00169

    authors: Corbit LH,Janak PH

    更新日期:2016-10-10 00:00:00

  • The Therapeutic Community: A Unique Social Psychological Approach to the Treatment of Addictions and Related Disorders.

    abstract::The evolution of the contemporary Therapeutic Community (TC) for addictions over the past 50 years may be characterized as a movement from the marginal to the mainstream of substance abuse treatment and human services. TCs currently serve a wide array of clients and their diverse problems; through advances in research...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00786

    authors: De Leon G,Unterrainer HF

    更新日期:2020-08-06 00:00:00

  • Preliminary Indications That First Semester Students From Academic Households Exhibit Higher Hair Cortisol Concentrations Than Their Peers From Nonacademic Households.

    abstract::Previous research has extensively addressed social disparity in education using certain aspects, including the stress differences between students from nonacademic families and those from academic families during the transition from secondary school to a university. However, this issue has not yet been fully understoo...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00580

    authors: Bertrams A,Minkley N

    更新日期:2020-06-24 00:00:00

  • Use of Technology to Promote Child Behavioral Health in the Context of Pediatric Care: A Scoping Review and Applications to Low- and Middle-Income Countries.

    abstract::Background: The burden of mental, neurological, and substance (MNS) disorders is greater in low- and middle-income countries (LMICs). The rapid growth of digital health (i.e., eHealth) approaches offer new solutions for transforming pediatric mental health services and have the potential to address multiple resource a...

    journal_title:Frontiers in psychiatry

    pub_type:

    doi:10.3389/fpsyt.2019.00806

    authors: Huang KY,Lee D,Nakigudde J,Cheng S,Gouley KK,Mann D,Schoenthaler A,Chokshi S,Kisakye EN,Tusiime C,Mendelsohn A

    更新日期:2019-11-13 00:00:00

  • Modulation of Social Cognition via Hallucinogens and "Entactogens".

    abstract::Social cognition is a fundamental ability in human everyday lives. Deficits in social functioning also represent a core aspect of many psychiatric disorders. Yet, despite its significance, deficits in social cognition skills are insufficiently targeted by current treatments. Hallucinogens and entactogens have been sho...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2019.00881

    authors: Preller KH,Vollenweider FX

    更新日期:2019-12-03 00:00:00

  • Neurophysiological Face Processing Deficits in Patients With Chronic Schizophrenia: An MEG Study.

    abstract:Background:Neuropsychological studies have revealed that patients with schizophrenia (SZ) have facial recognition difficulties and a reduced visual evoked N170 response to human faces. However, detailed neurophysiological evidence of this face processing deficit in SZ with a higher spatial resolution has yet to be acqu...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.554844

    authors: Ohara N,Hirano Y,Oribe N,Tamura S,Nakamura I,Hirano S,Tsuchimoto R,Ueno T,Togao O,Hiwatashi A,Nakao T,Onitsuka T

    更新日期:2020-09-03 00:00:00

  • Is the HPA Axis as Target for Depression Outdated, or Is There a New Hope?

    abstract::Major depressive disorder (MDD) is a very common stress-related mental disorder that carries a huge burden for affected patients and the society. It is associated with a high mortality that derives from suicidality and the development of serious medical conditions such as heart diseases, diabetes, and stroke. Although...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2019.00101

    authors: Menke A

    更新日期:2019-02-28 00:00:00

  • Vocational Profile and Correlates of Employment in People With Schizophrenia: The Role of Avolition.

    abstract:Objective:Employment was associated with recovery in individuals with schizophrenia. Our study aimed to delineate the vocational profile and investigate factors associated with likelihood of employment in individuals with schizophrenia. Materials and Methods:276 community dwelling outpatients with schizophrenia were r...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00856

    authors: Ang MS,Rekhi G,Lee J

    更新日期:2020-08-27 00:00:00

  • Resonance-Paced Breathing Alters Neural Response to Visual Cues: Proof-of-Concept for a Neuroscience-Informed Adjunct to Addiction Treatments.

    abstract::Conscious attempts to regulate alcohol and drug use are often undermined by automatic attention and arousal processes that are activated in the context of salient cues. Response to these cues involves body and brain signals that are linked via dynamic feedback loops, yet no studies have targeted the cardiovascular sys...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00624

    authors: Bates ME,Lesnewich LM,Uhouse SG,Gohel S,Buckman JF

    更新日期:2019-09-05 00:00:00

  • Association Between Plasma Metabolites and Psychometric Scores Among Children With Developmental Disabilities: Investigating Sex-Differences.

    abstract::Background: Developmental disabilities are defined by delays in learning, language, and behavior, yet growing evidence has revealed disturbances in metabolic systems that may also be present. Little is known about whether these metabolic issues contribute to the symptoms or severity of these disabilities, or whether s...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.579538

    authors: Sotelo-Orozco J,Abbeduto L,Hertz-Picciotto I,Slupsky CM

    更新日期:2020-12-22 00:00:00

  • A Randomized Controlled Trial on Mutual Support Group Intervention for Families of People With Recent-Onset Psychosis: A Four-Year Follow-Up.

    abstract::Introduction: Recent research in Western countries has indicated that family interventions in schizophrenia and other psychotic disorders can reduce patient relapse and improve medication compliance. Few studies have addressed Chinese and Asian populations. This study tested the long-term effects of a 9-month family-l...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00710

    authors: Chien WT,Bressington D,Chan SWC

    更新日期:2018-12-18 00:00:00

  • Increased Amplitude of Low-Frequency Fluctuation in Right Angular Gyrus and Left Superior Occipital Gyrus Negatively Correlated With Heroin Use.

    abstract::Abnormal amplitude of low-frequency fluctuation has been implicated in heroin addiction. However, previous studies lacked consistency and didn't consider the impact of confounding factors such as methadone and alcohol. Fifty-one heroin-dependent (HD) individuals and 40 healthy controls underwent resting-state function...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00492

    authors: Luo J,Yang R,Yang W,Duan C,Deng Y,Zhang J,Chen J,Liu J

    更新日期:2020-07-03 00:00:00

  • Lifestyle Interventions and Prevention of Suicide.

    abstract::Over the past years, there has been a growing interest in the association between lifestyle psychosocial interventions, severe mental illness, and suicide risk. Patients with severe mental disorders have higher mortality rates, poor health states, and higher suicide risk compared to the general population. Lifestyle b...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00567

    authors: Berardelli I,Corigliano V,Hawkins M,Comparelli A,Erbuto D,Pompili M

    更新日期:2018-11-06 00:00:00

  • Death Associated With Coronavirus (COVID-19) Infection in Individuals With Severe Mental Disorders in Sweden During the Early Months of the Outbreak-An Exploratory Cross-Sectional Analysis of a Population-Based Register Study.

    abstract::Background: Individuals with severe mental disorder (SMD) have a higher risk of somatic comorbidity and mortality than the rest of the population. We set up a population-based study to assess whether individuals with SMD had a higher risk of death associated with a COVID-19 infection (COVID-19 associated death) than i...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.609579

    authors: Maripuu M,Bendix M,Öhlund L,Widerström M,Werneke U

    更新日期:2021-01-08 00:00:00

  • Semantic Memory Organization in Japanese Patients With Schizophrenia Examined With Category Fluency.

    abstract:Background:Disorganization of semantic memory in patients with schizophrenia has been studied by referring to their category fluency performance. Recently, data-mining techniques such as singular value decomposition (SVD) analysis have been reported to be effective in elucidating the latent semantic memory structure in...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00087

    authors: Sumiyoshi C,Fujino H,Sumiyoshi T,Yasuda Y,Yamamori H,Fujimoto M,Hashimoto R

    更新日期:2018-03-21 00:00:00

  • Imaging Genetics Towards a Refined Diagnosis of Schizophrenia.

    abstract::Current diagnoses of schizophrenia and related psychiatric disorders are classified by phenomenological principles and clinical descriptions while ruling out other symptoms and conditions. Specific biomarkers are needed to assist the current diagnostic system. However, complicated gene and environment interactions ind...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2019.00494

    authors: Jiang W,King TZ,Turner JA

    更新日期:2019-07-12 00:00:00

  • Decision-Making Dysfunctions of Counterfactuals in Depression: Who Might I have Been?

    abstract::Cognitive neuroscience enables us now to decompose major depressive disorder into dysfunctional component processes and relate these processes to specific neural substrates. This approach can be used to illuminate the biological basis of altered psychological processes in depression, including abnormal decision-making...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2013.00143

    authors: Howlett JR,Paulus MP

    更新日期:2013-11-08 00:00:00

  • Decision-Making in Suicidal Behavior: The Protective Role of Loss Aversion.

    abstract:Background:Loss aversion is a central and well operationalized trait behavior that describes the tendency for humans to strongly prefer avoiding losses to making equivalent gains. Human decision-making is thus biased toward safer choices. Aim:The aim of this study was to explore the relationship between loss aversion ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00116

    authors: Hadlaczky G,Hökby S,Mkrtchian A,Wasserman D,Balazs J,Machín N,Sarchiapone M,Sisask M,Carli V

    更新日期:2018-04-05 00:00:00

  • The Effect of Insomnia on Cortical Excitability in Patients With Generalized Anxiety Disorder.

    abstract::The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00755

    authors: Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

    更新日期:2019-01-10 00:00:00

  • No Laughing Matter: Presence, Consumption Trends, Drug Awareness, and Perceptions of "Hippy Crack" (Nitrous Oxide) among Young Adults in England.

    abstract::In clinical settings, nitrous oxide gas is a safe anesthetic used during childbirth, in dentistry, and to relieve anxiety in emergencies. Colloquially known as "hippy crack"' or "laughing gas," it is increasingly taken recreationally for its euphoric and relaxing effects and hallucinogenic properties. Using a self-rep...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00312

    authors: Ehirim EM,Naughton DP,Petróczi A

    更新日期:2018-01-22 00:00:00

  • Preliminary Reliability and Validity of the DMRS-SR-30, a Novel Self-Report Measure Based on the Defense Mechanisms Rating Scales.

    abstract::Defense mechanisms are psychological factors that influence emotional distress and quality of life. There are a number of measures assessing the construct of defense mechanisms, but only few available instruments reflect the gold-standard theoretical hierarchical organization of defenses. We report on the development ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00870

    authors: Di Giuseppe M,Perry JC,Lucchesi M,Michelini M,Vitiello S,Piantanida A,Fabiani M,Maffei S,Conversano C

    更新日期:2020-08-26 00:00:00

  • Novel Contribution of Secreted Amyloid-β Precursor Protein to White Matter Brain Enlargement in Autism Spectrum Disorder.

    abstract::The most replicated neuroanatomical finding in autism is the tendency toward brain overgrowth, especially in younger children. Research shows that both gray and white matter are enlarged. Proposed mechanisms underlying brain enlargement include abnormal inflammatory and neurotrophic signals that lead to excessive, abe...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2019.00165

    authors: Sokol DK,Maloney B,Westmark CJ,Lahiri DK

    更新日期:2019-04-10 00:00:00

  • Involuntary Autobiographical Memories in Schizophrenia: Characteristics and Conditions of Elicitation.

    abstract::Involuntary autobiographical memories are mental representations of personally experienced past events that come to mind spontaneously, with no preceding attempt to recall them. They have been showed to be more frequent and more emotional in the psychosis continuum. Although schizophrenia is strongly associated with t...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.567189

    authors: Allé MC,Berna F,Danion JM,Berntsen D

    更新日期:2020-10-09 00:00:00

  • Rejection Sensitivity Mediates the Relationship Between Social-Interpersonal Stressors and Depressive Symptoms in Military Context.

    abstract:Background:Depression is pervasive in the military context and is likely to elicit lasting negative effects on health. Based on interpersonal models, social-interpersonal stressors are significantly associated with the development and maintenance of depression. However, little is known about the mechanisms by which the...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00447

    authors: Wang J,Cheng X,Xu K,Xu H,Wang H,Feng Z

    更新日期:2020-06-18 00:00:00

  • Effects of Increasing the Negativity of Implicit Outcome Expectancies on Internet Gaming Impulsivity.

    abstract::Outcome expectancies have been found to play important roles in addictive behaviors. Research has shown that implicit outcome expectancies (OE) were significantly correlated with Internet gaming behaviors among players with Internet gaming disorder (IGD). However, few empirical studies have further examined the relati...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00336

    authors: Hou S,Fang X,Zhou N,Cai P

    更新日期:2020-04-29 00:00:00