Abstract:
:The full spectrum of activities of the tumor suppressor p53 (TP53) has not been completely elucidated yet. Recently, it was demonstrated that TP53 communicates with the metabolic regulator mechanistic target of rapamycin (MTOR) to determine whether stressed cells undergo cell death, reversible quiescence or irreversible senescence, thereby adding yet another level of complexity to the signaling network that emanate from TP53.
journal_name
Aging (Albany NY)journal_title
Agingauthors
Galluzzi L,Kepp O,Kroemer Gdoi
10.18632/aging.100202subject
Has Abstractpub_date
2010-09-01 00:00:00pages
535-7issue
9issn
1945-4589pii
100202journal_volume
2pub_type
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