Impact of a theoretically based sex education programme (SHARE) delivered by teachers on NHS registered conceptions and terminations: final results of cluster randomised trial.

abstract：OBJECTIVE:To determine whether failure to adequately adjust for a reported 40% misclassification of use of in vitro fertilisation (IVF) as reported in a Swedish study could have led to a false finding that folic acid increases dizygotic twinning. DESIGN:Modelling with population based data. SETTING:Swedish vital reco...

journal_title：BMJ (Clinical research ed.)

authors： Berry RJ,Kihlberg R,Devine O

更新日期：2005-04-09 00:00:00

abstract：:Fetomaternal haemorrhage was studied after 68 consecutive fetal intravascular transfusions performed in 20 patients with Rh isoimmunisation. alpha Fetoprotein concentration was assayed in maternal blood taken before, and immediately after each transfusion and three and 24 hours later. An increase of 50% or more in the...

journal_title：BMJ (Clinical research ed.)

authors： Nicolini U,Kochenour NK,Greco P,Letsky EA,Johnson RD,Contreras M,Rodeck CH

更新日期：1988-11-26 00:00:00

abstract：OBJECTIVE:To test the hypothesis that radiography of the lumbar spine in patients with low back pain is not associated with improved clinical outcomes or satisfaction with care. DESIGN:Randomised unblinded controlled trial. SETTING:73 general practices in Nottingham, north Nottinghamshire, southern Derbyshire, north ...

journal_title：BMJ (Clinical research ed.)

authors： Kendrick D,Fielding K,Bentley E,Kerslake R,Miller P,Pringle M

更新日期：2001-02-17 00:00:00

abstract：OBJECTIVE:To investigate clinical trialists' opinions and experiences of sharing of clinical trial data with investigators who are not directly collaborating with the research team. DESIGN AND SETTING:Cross sectional, web based survey. PARTICIPANTS:Clinical trialists who were corresponding authors of clinical trials ...

journal_title：BMJ (Clinical research ed.)

authors： Rathi V,Dzara K,Gross CP,Hrynaszkiewicz I,Joffe S,Krumholz HM,Strait KM,Ross JS

更新日期：2012-11-20 00:00:00

abstract：:The International AIDS Vaccine Initiative, based in New York, US, was established in 1996 to develop a safe and affordable AIDS vaccine. It is funded by a number of large foundations and charities, the British government, and the World Bank. The Initiative's first 2 large projects, 2 research programs into a vaccine...

journal_title：BMJ (Clinical research ed.)

authors： Matthews H

更新日期：1998-12-05 00:00:00

abstract：OBJECTIVE:To examine the role of peak bone mass and subsequent postmenopausal bone loss in the development of osteoporosis and the reliability of identifying women at risk from one bone mass measurement and one biochemical assessment of the future bone loss. DESIGN:Population based study. SETTING:Outpatient clinic fo...

journal_title：BMJ (Clinical research ed.)

authors： Hansen MA,Overgaard K,Riis BJ,Christiansen C

更新日期：1991-10-19 00:00:00

abstract：OBJECTIVES:To examine trends over time in the rates of admission to hospital for accidents of preschool children and to study patterns of repeated admissions for accidents in these children. DESIGN:Analysis of linked, routine abstracts of hospital inpatient records for accidents. SETTING:Six districts in the Oxford R...

journal_title：BMJ (Clinical research ed.)

authors： Sellar C,Ferguson JA,Goldacre MJ

更新日期：1991-01-05 00:00:00

abstract：OBJECTIVES:To determine whether fibrinogen and lipid concentrations are risk factors for ischaemic stroke. DESIGN:Case-control study with a population based comparison within the overall study. SETTING:Oxfordshire community stroke project and a neurology clinic. SUBJECTS:105 patients who had a transient ischaemic at...

journal_title：BMJ (Clinical research ed.)

authors： Qizilbash N,Jones L,Warlow C,Mann J

更新日期：1991-09-14 00:00:00

abstract：OBJECTIVES:To examine the association between income inequality and the risk of mortality and readmission within 30 days of hospitalization. DESIGN:Retrospective cohort study of Medicare beneficiaries in the United States. Hierarchical, logistic regression models were developed to estimate the association between inco...

journal_title：BMJ (Clinical research ed.)

authors： Lindenauer PK,Lagu T,Rothberg MB,Avrunin J,Pekow PS,Wang Y,Krumholz HM

更新日期：2013-02-14 00:00:00

abstract：OBJECTIVE:To observe the effects of stimulation of the sacral anterior roots on anorectal and low colonic pressures and to programme implanted stimulators to produce defecation. DESIGN:Prospective study of 12 consecutive patients. SETTING:Spinal injuries unit and university gastrointestinal physiology department. PA...

journal_title：BMJ (Clinical research ed.)

authors： MacDonagh RP,Sun WM,Smallwood R,Forster D,Read NW

更新日期：1990-06-09 00:00:00

abstract：OBJECTIVE:To identify the number of patients who were misdiagnosed as being in the vegetative state and their characteristics. DESIGN:Retrospective study of the clinical records of the medical, occupational therapy, and clinical psychology departments. SETTING:20 bed unit specialising in the rehabilitation of patient...

journal_title：BMJ (Clinical research ed.)

authors： Andrews K,Murphy L,Munday R,Littlewood C

更新日期：1996-07-06 00:00:00

abstract：:Molecular techniques have revolutionised our knowledge of cell and tissue function in both health and disease. We already have new and powerful treatments based on an understanding of communication between cells by messenger molecules called cytokines. Furthermore, there is great therapeutic promise in defining molecu...

journal_title：BMJ (Clinical research ed.)

authors： Savill J

更新日期：1997-01-18 00:00:00

abstract：OBJECTIVE:To evaluate the clinical benefit of lipid lowering drug treatment in patients with and without diabetes mellitus, for primary and secondary prevention. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Cochrane, Medline, Embase, and reference lists up to April 2004. STUDY SELECTION:Randomised, place...

journal_title：BMJ (Clinical research ed.)

authors： Costa J,Borges M,David C,Vaz Carneiro A

更新日期：2006-05-13 00:00:00

abstract：OBJECTIVE:To test whether a drug review and symptom self management and lifestyle advice intervention by community pharmacists could reduce hospital admissions or mortality in heart failure patients. DESIGN:Randomised controlled trial. SETTING:Home based intervention in heart failure patients. PARTICIPANTS:293 patie...

journal_title：BMJ (Clinical research ed.)

authors： Holland R,Brooksby I,Lenaghan E,Ashton K,Hay L,Smith R,Shepstone L,Lipp A,Daly C,Howe A,Hall R,Harvey I

更新日期：2007-05-26 00:00:00

abstract：:The issue of children on hunger strike (voluntary total fasting) has not been reported before. The World Medical Association Declaration of Tokyo 1975 and the Declaration of Malta 1991 (revised 1992) provide clinicians with guidelines for the management of adult patients on hunger strike but do not mention children. W...

journal_title：BMJ (Clinical research ed.)

authors： Mok A,Nelson EA,Murphy J,Hampson A,Hendriks JH

更新日期：1996-02-24 00:00:00

abstract：OBJECTIVE:To assess whether mini flow meters used to measure peak expiratory flow can track changes in lung function and indicate clinically important changes. DESIGN:Comparison of measurements with a spirometer and different brands of mini flow meter; the meters were allocated to subjects haphazardly. SUBJECTS:12 bo...

journal_title：BMJ (Clinical research ed.)

authors： Sly PD,Cahill P,Willet K,Burton P

更新日期：1994-02-26 00:00:00

abstract：OBJECTIVE:To test the hypothesis of an association between neonatal intramuscular vitamin K and childhood leukaemia and other cancers. DESIGN:Population based case-control study with data abstracted from hospital records. SETTING:Scotland. SUBJECTS:Children aged 0-14 years resident in Scotland from 1991-4 and diagno...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Juszczak E,Findlay E,Smith K

更新日期：1998-01-17 00:00:00

abstract：:Research in general practice is becoming increasingly popular, and most general practitioners will sooner or later have to decide whether to become involved with clinical trials sponsored by drug companies. This paper outlines the advantages and disadvantages of multicentre research--based on experience of running a r...

journal_title：BMJ (Clinical research ed.)

authors： Waldron HA,Cookson RF

更新日期：1993-11-20 00:00:00

abstract：OBJECTIVE:To investigate the contribution of neuroleptic drugs to cognitive decline in dementia. DESIGN:Two year prospective, longitudinal study consisting of interviews every four months, with necropsy follow up. SETTING:Community settings in Oxfordshire. SUBJECTS:71 subjects with dementia, initially living at home...

journal_title：BMJ (Clinical research ed.)

authors： McShane R,Keene J,Gedling K,Fairburn C,Jacoby R,Hope T

更新日期：1997-01-25 00:00:00

abstract：:Several forces have resulted in the creation in Tayside of the first formally integrated unit of undergraduate and postgraduate education in general practice in the United Kingdom. Forces that helped this integration included the desire for change, national developments in education, financial support through funds se...

journal_title：BMJ (Clinical research ed.)

authors： Bain J,Scott R,Snadden D

更新日期：1995-06-17 00:00:00

abstract：OBJECTIVE:To determine the relation between mothers' self reported drinking habits before, during, and after pregnancy and infants' mental and motor development at 18 months of age. DESIGN:Follow up study of all singleton live births born to primigravidas living in Dundee and booked into antenatal clinics from 1 May 1...

journal_title：BMJ (Clinical research ed.)

authors： Forrest F,Florey CD,Taylor D,McPherson F,Young JA

更新日期：1991-07-06 00:00:00

abstract：:Stroke is the leading cause of long term disability in developed countries and one of the top causes of mortality worldwide. The past decade has seen substantial advances in the diagnostic and treatment options available to minimize the impact of acute ischemic stroke. The key first step in stroke care is early identi...

journal_title：BMJ (Clinical research ed.)

authors： Phipps MS,Cronin CA

更新日期：2020-02-13 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intensive geriatric rehabilitation on demented patients with hip fracture. DESIGN:Preplanned subanalysis of randomised intervention study. Settting: Jyväskylä Central Hospital, Finland. PARTICIPANTS:243 independently living patients aged 65 years or older admitted to hospital with ...

journal_title：BMJ (Clinical research ed.)

authors： Huusko TM,Karppi P,Avikainen V,Kautiainen H,Sulkava R

更新日期：2000-11-04 00:00:00

abstract：:The identification of the gene for cystic fibrosis has led to the possibility of population based screening for carriers of cystic fibrosis to identify couples at risk of having an affected child. Pilot studies have shown that screening is feasible and does not cause untoward anxiety, though the uptake of testing vari...

journal_title：BMJ (Clinical research ed.)

authors： Modell M

更新日期：1993-10-02 00:00:00

abstract：OBJECTIVES:To investigate the consequences of longstanding obesity on left ventricular mass and structure and to examine the effects of weight loss on these variables. DESIGN:Cross sectional survey and controlled intervention study. SETTING:City of Gothenburg and surrounding areas. Sweden. SUBJECTS:41 obese patients...

journal_title：BMJ (Clinical research ed.)

authors： Karason K,Wallentin I,Larsson B,Sjöström L

更新日期：1997-10-11 00:00:00

abstract：OBJECTIVE:To assess the costs and health effects of a range of interventions for preventing the spread of HIV and for treating people with HIV/AIDS in the context of the millennium development goal for combating HIV/AIDS. DESIGN:Cost effectiveness analysis based on an epidemiological model. SETTING:Analyses undertake...

journal_title：BMJ (Clinical research ed.)

authors： Hogan DR,Baltussen R,Hayashi C,Lauer JA,Salomon JA

更新日期：2005-12-17 00:00:00

abstract：OBJECTIVE:To evaluate risk of late life coronary heart disease associated with being overweight in late middle or old age and to assess whether weight change modifies this risk. DESIGN:Longitudinal study of subjects in the epidemiological follow up study of the national health and nutrition examination survey I. SETT...

journal_title：BMJ (Clinical research ed.)

authors： Harris TB,Launer LJ,Madans J,Feldman JJ

更新日期：1997-06-21 00:00:00

abstract：OBJECTIVE:To examine the association between warfarin treatment and longitudinal outcomes after ischemic stroke in patients with atrial fibrillation in community practice. DESIGN:Observational study. SETTING:Hospitals (n = 1487) participating in the Get With The Guidelines (GWTG)-Stroke program in the United States, ...

journal_title：BMJ (Clinical research ed.)

authors： Xian Y,Wu J,O'Brien EC,Fonarow GC,Olson DM,Schwamm LH,Bhatt DL,Smith EE,Suter RE,Hannah D,Lindholm B,Maisch L,Greiner MA,Lytle BL,Pencina MJ,Peterson ED,Hernandez AF

更新日期：2015-07-31 00:00:00

abstract：OBJECTIVE:To examine the associations between neuraxial anaesthesia or general anaesthesia and clinical outcomes, length of hospital stay, and readmission in adults undergoing lower limb revascularisation surgery. DESIGN:Comparative effectiveness study using linked, validated, population based databases. SETTING:Onta...

journal_title：BMJ (Clinical research ed.)

authors： Roberts DJ,Nagpal SK,Kubelik D,Brandys T,Stelfox HT,Lalu MM,Forster AJ,McCartney CJ,McIsaac DI

更新日期：2020-11-25 00:00:00

abstract：OBJECTIVE:To examine the associations of a vegetarian diet and dietary fibre intake with risk of diverticular disease. DESIGN:Prospective cohort study. SETTING:The EPIC-Oxford study, a cohort of mainly health conscious participants recruited from around the United Kingdom. PARTICIPANTS:47,033 men and women living in...

journal_title：BMJ (Clinical research ed.)

authors： Crowe FL,Appleby PN,Allen NE,Key TJ

更新日期：2011-07-19 00:00:00