The interdisciplinary treatment of unruptured intracranial aneurysms.

abstract：BACKGROUND:Age-related macular degeneration (AMD) is a common retinal disease in older people. In Europe, about 1.6% of persons over age 65 and more than 13% of persons over age 85 have late-stage AMD, which can severely impair vision. The development of AMD is influenced both by environmental factors and by a strong h...

journal_title：Deutsches Arzteblatt international

authors： Weber BH,Charbel Issa P,Pauly D,Herrmann P,Grassmann F,Holz FG

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:In endocrine orbitopathy (EO), disfiguring proptosis and diplopia impair patients' quality of life both at home and at work. METHODS:From late 2006 to the beginning of 2008, 250 outpatients in an interdisciplinary thyroid and eye clinic filled out a questionnaire about their quality of life, occupational di...

journal_title：Deutsches Arzteblatt international

authors： Ponto KA,Pitz S,Pfeiffer N,Hommel G,Weber MM,Kahaly GJ

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:With improved cure rates of cancer in children and adolescents, the long-term effects of oncological treatment, including impaired fertility, have become an important clinical issue. METHODS:In 2008, we conducted a nationwide survey in Germany in which we asked 4689 female and male patients who had been tre...

journal_title：Deutsches Arzteblatt international

authors： Balcerek M,Reinmuth S,Hohmann C,Keil T,Borgmann-Staudt A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:About 17% of all children suffer from a mental disorder in early childhood, defined as the period up to the age of 6 years. METHODS:This review is based on publications retrieved by a selective search in PubMed and the Web of Science, as well as on the authors' clinical and scientific experience. RESULTS:I...

journal_title：Deutsches Arzteblatt international

authors： von Klitzing K,Döhnert M,Kroll M,Grube M

更新日期：2015-05-25 00:00:00

abstract：BACKGROUND:In this study, we investigated the measures currently being taken in German hospitals to prevent infection with methicillin-resistant strains of Staphylococcus aureus (MRSA). To this end, we circulated a questionnaire among hospitals participating in the MRSA-KISS module. "KISS" in the name of this project s...

journal_title：Deutsches Arzteblatt international

authors： Chaberny IF,Wriggers A,Behnke M,Gastmeier P

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The percentage of organ donors among the German population is very low, and the supply of organs does not meet the demand. Relatively few organ explantations are performed in Germany, compared to other countries. The central element leading up to organ explantation is the donor's consent. This can be express...

journal_title：Deutsches Arzteblatt international

authors： Küpers M,Dudda M,Kauther MD,Schwarz B,Hausen SA,Jöckel KH

更新日期：2020-03-13 00:00:00

abstract：BACKGROUND:Monoclonal antibodies (mAb) and fusion proteins (FP) are increasingly being used in children and adolescents. In this review, we analyze the evidence for their safety and efficacy in the treatment of the most common chronic inflammatory diseases. METHODS:We systematically searched PubMed, AWMF.org, and othe...

journal_title：Deutsches Arzteblatt international

authors： Niehues T,Özgür TT

更新日期：2019-10-18 00:00:00

abstract：BACKGROUND:Pulsatile tinnitus, unlike idiopathic tinnitus, usually has a specific, identifiable cause. Nonetheless, uncertainty often arises in clinical practice about the findings to be sought and the strategy for work-up. METHODS:Selective literature review and evaluation of our own series of patients. RESULTS:Puls...

journal_title：Deutsches Arzteblatt international

authors： Hofmann E,Behr R,Neumann-Haefelin T,Schwager K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Many patients in German hospitals complain of inadequate treatment of their postoperative pain. Hospital-related structural and procedural variables may affect pain perception and patient satisfaction. We studied the association of individual variables with outcome quality. METHODS:Data from the years 2011 ...

journal_title：Deutsches Arzteblatt international

authors： Meißner W,Komann M,Erlenwein J,Stamer U,Scherag A

更新日期：2017-03-10 00:00:00

abstract：BACKGROUND:In view of the rise in antibiotic resistance and Clostridium difficile superinfection, close monitoring of antibiotic prescribing practices is essential so that targeted quality assurance measures can be taken. METHODS:We analyzed nationwide data from multiple statutory health insurance carriers on prescrip...

journal_title：Deutsches Arzteblatt international

authors： Bätzing-Feigenbaum J,Schulz M,Schulz M,Hering R,Kern WV

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Direct (non-vitamin-K-dependent) oral anticoagulants (DOAC) are given as an alternative to vitamin K antagonists (VKA) to prevent stroke and embolic disease in patients with atrial fibrillation that is not due to pathology of the heart valves. Fatal hemorrhage is rarer when DOACs are given (nonvalvular atria...

journal_title：Deutsches Arzteblatt international

authors： Maegele M,Grottke O,Schöchl H,Sakowitz OA,Spannagl M,Koscielny J

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Multi-center observational studies in surgery can yield important findings, as long as they are appropriately designed and monitored and employ modern methods of statistical analysis. METHODS:In a multi-center quality assurance study carried out in 346 German hospitals from 2000 to 2004, data were collected...

journal_title：Deutsches Arzteblatt international

authors： Kube R,Gastinger I,Mroczkowski P,Ptok H,Wolff S,Lippert H

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Prostatic cancer (PCa) is the most common cancer in men in Germany. The goal of this review is to define the indication for hormonal treatment in patients over age 70. METHODS:A selective search of the literature up to 2008 for the terms "prostate cancer", "androgen suppression and deprivation", "hormone th...

journal_title：Deutsches Arzteblatt international

authors： Pfitzenmaier J,Altwein JE

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The introduction of neurological stroke units and of thrombolysis with the intravenous (IV) administration of recombinant tissue-type plasminogen activator (tPA) have markedly improved the treatment of stroke. Five randomized trials of catheter-based interventional treatment of stroke with special stents wer...

journal_title：Deutsches Arzteblatt international

authors： Fiehler J,Gerloff C

更新日期：2015-12-04 00:00:00

abstract：BACKGROUND:Systematic reviews provide a structured summary of the results of trials that have been carried out on any particular subject. If the data from multiple trials are sufficiently homogenous, a meta-analysis can be performed to calculate pooled effect estimates. Traditional meta-analysis involves groups of tria...

journal_title：Deutsches Arzteblatt international

authors： Kiefer C,Sturtz S,Bender R

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:Eliminating measles in Europe by 2015 is a WHO health goal. In Germany, physicians are legally required to report measles cases, yet it seems likely that reporting is less than universal. The goal of this study is to compare the number of measles cases that are reflected by data from the statutory health ins...

journal_title：Deutsches Arzteblatt international

authors： Mette A,Reuss AM,Feig M,Kappelmayer L,Siedler A,Eckmanns T,Poggensee G

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Pre-hospital hypotension in trauma patients is associated with high mortality. Especially for patients with severe traumatic brain injury (TBI), arterial normotension or even hypertension (AHT) is considered an important mechanism for sustaining adequate cerebral perfusion pressure. The effect of pre-hospita...

journal_title：Deutsches Arzteblatt international

authors： Sellmann T,Miersch D,Kienbaum P,Flohé S,Schneppendahl J,Lefering R,DGU Trauma Registry.

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Although the number of elderly patients with fractures is increasing, there have been only a few studies to date of the efficacy of collaborative treatment by trauma surgeons and geriatricians. METHODS:Data on patients over age 75 with femoral neck, trochanteric, proximal humeral, and pelvic ring fractures ...

journal_title：Deutsches Arzteblatt international

authors： Grund S,Roos M,Duchene W,Schuler M

更新日期：2015-02-13 00:00:00

abstract：BACKGROUND:Stroke is the third most common cause of death in industrialized countries, accounting for more than 10% of deaths over age 65. Most strokes are due to arteriosclerosis. Regular physical activity lowers arterial blood pressure and body weight and improves glucose and lipid metabolism, thereby slowing the dev...

journal_title：Deutsches Arzteblatt international

authors： Reimers CD,Knapp G,Reimers AK

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Red eye can arise as a manifestation of many different systemic and ophthalmological diseases. The physician whom the patient first consults for this problem is often not an ophthalmologist. A correct assessment of the urgency of the situation is vitally important for the planning of further diagnostic evalu...

journal_title：Deutsches Arzteblatt international

authors： Frings A,Geerling G,Schargus M

更新日期：2017-04-28 00:00:00

abstract：BACKGROUND:Infections with multidrug-resistant gram-negative bacteria are hard to treat and cause high morbidity and mortality. The direct transmission of such pathogens is well documented, and measures to protect other patients would seem indicated. Nonetheless, evidence-based recommendations are not yet available bec...

journal_title：Deutsches Arzteblatt international

authors： Mattner F,Bange FC,Meyer E,Seifert H,Wichelhaus TA,Chaberny IF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The estimated prevalence of fetal alcohol syndrome (FAS) is 8 for every 1000 live births. FAS has serious, lifelong consequences for the affected children and their families. A variety of professionals deal with persons who have FAS, including pediatricians, general practitioners, neurologists, gynecologists...

journal_title：Deutsches Arzteblatt international

authors： Landgraf MN,Nothacker M,Kopp IB,Heinen F

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:The range of indications for vitreoretinal surgery has widened in recent years, and intraocular gas application is frequently performed as part of retinal surgery, with the aim of achieving long-acting tamponade. METHODS:Selective literature review. RESULTS:An intraocular gas bubble containing perfluorop...

journal_title：Deutsches Arzteblatt international

authors： Silvanus MT,Moldzio P,Bornfeld N,Peters J

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Delirium is a common complication in elderly hospitalized patients. It prolongs the length of hospital stay, raises costs, increases the workload of the nursing staff, and may necessitate transfer of the patient to a nursing home. The risk of postoperative delirium is particularly high in elderly patients wi...

journal_title：Deutsches Arzteblatt international

authors： Kratz T,Heinrich M,Schlauß E,Diefenbacher A

更新日期：2015-04-24 00:00:00

abstract：INTRODUCTION:Autopsy studies of persons who died of cancer have shown the lungs to be the sole site of metastasis in about 20% of cases. The resection of pulmonary metastases is indicated for palliative purposes if they contain a large volume of necrotic tumor, infiltrate the thoracic wall to produce pain, or cause hem...

journal_title：Deutsches Arzteblatt international

authors： Pfannschmidt J,Egerer G,Bischof M,Thomas M,Dienemann H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:For prospective parents at risk of transmitting a monogenic disease, polar body analysis is an option for pre-conception genetic diagnosis. In Germany, polar body analysis is currently performed in only two centers (Lübeck and Regensburg). METHODS:The authors present a clinical series of 9 couples at risk f...

journal_title：Deutsches Arzteblatt international

authors： Griesinger G,Bündgen N,Salmen D,Schwinger E,Gillessen-Kaesbach G,Diedrich K

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Isolated non-compaction cardiomyopathy (NCCM) was first described in 1984. This disorder, a primary genetic cardiomyopathy, is now attracting increased attention. METHOD:The current state of the epidemiology, pathogenesis, pathophysiology, clinical features, diagnosis, treatment, and prognosis of NCCM are d...

journal_title：Deutsches Arzteblatt international

authors： Engberding R,Stöllberger C,Ong P,Yelbuz TM,Gerecke BJ,Breithardt G

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Studies from multiple countries have shown that acute kidney injury (AKI) in hospitalized patients is associated with mortality and morbidity. There are no reliable data at present on the incidence and mortality of AKI episodes among hospitalized patients in Germany. The utility of administrative codings of ...

journal_title：Deutsches Arzteblatt international

authors： Khadzhynov D,Schmidt D,Hardt J,Rauch G,Gocke P,Eckardt KU,Schmidt-Ott KM

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:Pilonidal disease is an acute or chronic infection in the subcutaneous fatty tissue, mainly in the natal cleft. Its incidence in Germany in 2012 was 48 cases per 100 000 persons per year. METHODS:This review is based on pertinent publications retrieved by a selective literature search. RESULTS:The numerous...

journal_title：Deutsches Arzteblatt international

authors： Iesalnieks I,Ommer A

更新日期：2019-01-07 00:00:00

abstract：BACKGROUND:Because of the changing dietary habits of an aging population, hyperuricemia is frequently found in combination with other metabolic disorders. Longstanding elevation of the serum uric acid level can lead to the deposition of monosodium urate crystals, causing gout (arthritis, urate nephropathy, tophi). In G...

journal_title：Deutsches Arzteblatt international

authors： Tausche AK,Jansen TL,Schröder HE,Bornstein SR,Aringer M,Müller-Ladner U

更新日期：2009-08-01 00:00:00