Occupational noise exposure and Raynaud's phenomenon: a nested case-control study.

Abstract:

:The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud's phenomenon. In northern Sweden, a nested case-control study was performed on subjects reporting Raynaud's phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud's phenomenon (OR 1.10; 95% CI 0.83-1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud's phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00-3.81), and hearing loss was associated with reporting Raynaud's phenomenon (OR 1.52; 95% CI 1.03-2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud's phenomenon, but there was a dose-effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud's phenomenon. These findings offer some support for a common pathophysiological background for Raynaud's phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction.

authors

Stjernbrandt A,Abu Mdaighem M,Pettersson H

doi

10.1080/22423982.2021.1969745

keywords:

["(Mesh): Raynaud disease","Sweden","hand-arm vibration syndrome","hearing loss","heredity","noise","occupational"]

subject

Has Abstract

pub_date

2021-12-01 00:00:00

pages

1969745

issue

1

eissn

1239-9736

issn

2242-3982

journal_volume

80

pub_type

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