Geometric morphometrics defines shape differences in the cortical area map of C57BL/6J and DBA/2J inbred mice.

abstract：BACKGROUND:Cholecystokinin octapeptide (CCK-8), the most potent endogenous anti-opioid peptide, has been shown to regulate the processes of morphine dependence. In our previous study, we found that exogenous CCK-8 attenuated naloxone induced withdrawal symptoms. To investigate the precise effect of exogenous CCK-8 and ...

journal_title：BMC neuroscience

authors： Wen D,Ma CL,Zhang YJ,Meng YX,Ni ZY,Li SJ,Cong B

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:Reuptake of synaptic norepinephrine (NE) via the antidepressant-sensitive NE transporter (NET) supports efficient noradrenergic signaling and presynaptic NE homeostasis. Limited, and somewhat contradictory, information currently describes the axonal transport and localization of NET in neurons. RESULTS:We e...

journal_title：BMC neuroscience

authors： Matthies HJ,Han Q,Shields A,Wright J,Moore JL,Winder DG,Galli A,Blakely RD

更新日期：2009-06-23 00:00:00

abstract：BACKGROUND:To date, functional imaging studies of treatment-induced recovery from chronic aphasia only assessed short-term treatment effects after intensive language training. In the present study, we show with functional magnetic resonance imaging (fMRI), that different brain regions may be involved in immediate versu...

journal_title：BMC neuroscience

authors： Menke R,Meinzer M,Kugel H,Deppe M,Baumgärtner A,Schiffbauer H,Thomas M,Kramer K,Lohmann H,Flöel A,Knecht S,Breitenstein C

更新日期：2009-09-22 00:00:00

abstract：BACKGROUND:The integration of EEG and fMRI is attractive because of their complementary precision regarding time and space. But the relationship between the indirect hemodynamic fMRI signal and the more direct EEG signal is uncertain. Event-related EEG responses can be analyzed in two different ways, reflecting two dif...

journal_title：BMC neuroscience

authors： Foucher JR,Otzenberger H,Gounot D

更新日期：2003-09-19 00:00:00

abstract：BACKGROUND:Gap junction proteins, connexins, are expressed in most endocrine and exocrine glands in the body and are at least in some glands crucial for the hormonal secretion. To what extent connexins are expressed in neurons releasing hormones or neuropeptides from or within the central nervous system is, however, un...

journal_title：BMC neuroscience

authors： Westberg L,Sawa E,Wang AY,Gunaydin LA,Ribeiro AC,Pfaff DW

更新日期：2009-04-30 00:00:00

abstract：BACKGROUND:The megencephaly mouse, mceph/mceph, is epileptic and displays a dramatically increased brain volume and neuronal count. The responsible mutation was recently revealed to be an eleven base pair deletion, leading to a frame shift, in the gene encoding the potassium channel Kv1.1. The predicted MCEPH protein i...

journal_title：BMC neuroscience

authors： Persson AS,Klement G,Almgren M,Sahlholm K,Nilsson J,Petersson S,Arhem P,Schalling M,Lavebratt C

更新日期：2005-11-23 00:00:00

abstract：BACKGROUND:Alzheimer's Disease (AD) and Fronto temporal lobar dementia (FTLD) are common causes of dementia in the aging population for which limited therapeutical options are available. These disorders are associated with Tau accumulation. We have previously shown that Cerebrolysin™ (CBL), a neuropeptide mixture with ...

journal_title：BMC neuroscience

authors： Rockenstein E,Ubhi K,Trejo M,Mante M,Patrick C,Adame A,Novak P,Jech M,Doppler E,Moessler H,Masliah E

更新日期：2014-07-21 00:00:00

abstract：BACKGROUND:The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments. In the present study we performed a systematic characterization of the spatio-temporal patterns of S- and...

journal_title：BMC neuroscience

authors： Narayan DS,Ao J,Wood JPM,Casson RJ,Chidlow G

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Recovery following stroke depends on cellular plasticity in the perilesional zone (PZ). Doublecortin (DCX), a protein mainly labeling immature neurons in neurogenic niches is also highly expressed in the vicinity of focal cortical infarcts. Notably, the number of DCX+ cells positively correlates with the rec...

journal_title：BMC neuroscience

authors： Kunze A,Achilles A,Keiner S,Witte OW,Redecker C

更新日期：2015-04-15 00:00:00

abstract：BACKGROUND:Neurogenesis continues to occur throughout life but dramatically decreases with increasing age. This decrease is mostly related to a decline in proliferative activity as a result of an impoverishment of the microenvironment of the aged brain, including a reduction in trophic factors and increased inflammatio...

journal_title：BMC neuroscience

authors： Bachstetter AD,Pabon MM,Cole MJ,Hudson CE,Sanberg PR,Willing AE,Bickford PC,Gemma C

更新日期：2008-02-14 00:00:00

abstract：BACKGROUND:Post-traumatic stress disorder (PTSD) is an anxious disorder associated with low levels of corticosterone and enhanced negative feedback of the hypothalamic-pituitary-adrenal (HPA) axis. Previous studies showed that the amygdala not only has an excitatory effect on the HPA axis but also plays a key role in f...

journal_title：BMC neuroscience

authors： Han F,Ding J,Shi Y

更新日期：2014-06-19 00:00:00

abstract：BACKGROUND:Evoked potentials have been proposed to result from phase-locking of electroencephalographic (EEG) activities within specific frequency bands. However, the respective contribution of phasic activity and phase resetting of ongoing EEG oscillation remains largely debated. We here applied the EEGlab procedure i...

journal_title：BMC neuroscience

authors： Cheron G,Cebolla AM,De Saedeleer C,Bengoetxea A,Leurs F,Leroy A,Dan B

更新日期：2007-09-18 00:00:00

abstract：BACKGROUND:Functional magnetic resonance imaging (fMRI) in white matter has long been considered controversial. Recently, this viewpoint has been challenged by an emerging body of evidence demonstrating white matter activation in the corpus callosum. The current study aimed to determine whether white matter activation ...

journal_title：BMC neuroscience

authors： Gawryluk JR,Mazerolle EL,Brewer KD,Beyea SD,D'Arcy RC

更新日期：2011-06-14 00:00:00

abstract：:Numerous molecular factors orchestrate the development of the peripheral taste system. The unique anatomy/function of the taste system makes this system ideal for understanding the mechanisms by which these factors function; yet the taste system is underutilized for this role. This review focuses on some of the many f...

journal_title：BMC neuroscience

authors： Krimm RF

更新日期：2007-09-18 00:00:00

abstract：BACKGROUND:Recent work has suggested that the ovarian steroid 17beta-estradiol, at physiological concentrations, may exert protective effects in neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and acute ischemic stroke. While physiological concentrations of estrogen have consistently been s...

journal_title：BMC neuroscience

authors： Dhandapani KM,Brann DW

更新日期：2002-06-07 00:00:00

abstract：BACKGROUND:Imprinting behavior is one form of learning and memory in precocial birds. With the aim of elucidating of the neural basis for visual imprinting, we focused on visual information processing. RESULTS:A lesion in the visual wulst, which is similar functionally to the mammalian visual cortex, caused anterograd...

journal_title：BMC neuroscience

authors： Maekawa F,Komine O,Sato K,Kanamatsu T,Uchimura M,Tanaka K,Ohki-Hamazaki H

更新日期：2006-11-14 00:00:00

abstract：BACKGROUND:Given the reported inverse association between light and depressive mood, ambient light may also be associated with some of the brain regions in healthy subjects. The present study aims to investigate the effects of ambient light on glucose metabolism in the brain. We used the data of 28 healthy participants...

journal_title：BMC neuroscience

authors： Hirakawa H,Terao T,Hatano K,Kohno K,Ishii N

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:After unilateral cervical cord lesion at the C7/C8 border interrupting the dorsolateral funiculus in adult monkeys, neutralization of Nogo-A using a specific monoclonal antibody promoted sprouting of corticospinal (CS) axons rostral and caudal to the lesion and, in parallel, improved functional recovery. In ...

journal_title：BMC neuroscience

authors： Beaud ML,Schmidlin E,Wannier T,Freund P,Bloch J,Mir A,Schwab ME,Rouiller EM

更新日期：2008-01-14 00:00:00

abstract：BACKGROUND:During development the switch from a depolarizing to a hyperpolarizing action of GABA is a consequence of a decrease of the Na+-K+-2Cl- co-transporter (NKCC1, Cl--uptake) and increase of the K+-Cl- co-transporter (KCC2, Cl--extrusion) expression. However albino visual cortex neurons don't show a correspondin...

journal_title：BMC neuroscience

authors： Diykov D,Turchinovich A,Zoidl G,Hoffmann KP

更新日期：2008-06-30 00:00:00

abstract：BACKGROUND:Histone deacetylases (HDACs) are enzymes that modulate gene expression and cellular processes by deacetylating histones and non-histone proteins. While small molecule inhibitors of HDAC activity (HDACi) are used clinically in the treatment of cancer, pre-clinical treatment models suggest they also exert neur...

journal_title：BMC neuroscience

authors： Zhou Q,Dalgard CL,Wynder C,Doughty ML

更新日期：2011-05-26 00:00:00

abstract：BACKGROUND:Receptor-interacting protein 3 (RIP3), a member of RIP family proteins, has been shown to participate in programmed necrosis or necroptosis in cell biology studies. Evidence suggests that necroptosis may be a mode of neuronal death in the retina. RESULTS:In the present study we determined the expression of ...

journal_title：BMC neuroscience

authors： Huang JF,Shang L,Zhang MQ,Wang H,Chen D,Tong JB,Huang H,Yan XX,Zeng LP,Xiong K

更新日期：2013-02-02 00:00:00

abstract：BACKGROUND:Traumatic brain injury (TBI) initiates a complex sequence of destructive and neuroprotective cellular responses. The initial mechanical injury is followed by an extended time period of secondary brain damage. Due to the complicated pathological picture a better understanding of the molecular events occurring...

journal_title：BMC neuroscience

authors： von Gertten C,Flores Morales A,Holmin S,Mathiesen T,Nordqvist AC

更新日期：2005-11-30 00:00:00

abstract：BACKGROUND:The human inferior frontal junction area (IFJ) is critically involved in three main component processes of cognitive control (working memory, task switching and inhibitory control). As it overlaps with several areas in established anatomical labeling schemes, it is considered to be underreported as a functio...

journal_title：BMC neuroscience

authors： Sundermann B,Pfleiderer B

更新日期：2012-10-03 00:00:00

abstract：BACKGROUND:Bone morphogenic proteins (BMPs) promote the survival of neurons, suggesting a therapeutic application of BMPs in the treatment of acute and chronic neurodegenerative disorders. However, the application of recombinant BMPs in vivo is limited by their short half-life. To provide a continuous supply for functi...

journal_title：BMC neuroscience

authors： Heinonen AM,Rahman M,Dogbevia G,Jakobi H,Wölfl S,Sprengel R,Schwaninger M

更新日期：2014-03-11 00:00:00

abstract：BACKGROUND:Earlier functional imaging studies on visually induced self-motion perception (vection) disclosed a bilateral network of activations within primary and secondary visual cortex areas which was combined with signal decreases, i.e., deactivations, in multisensory vestibular cortex areas. This finding led to the...

journal_title：BMC neuroscience

authors： Becker-Bense S,Buchholz HG,zu Eulenburg P,Best C,Bartenstein P,Schreckenberger M,Dieterich M

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Following partial injury to the central nervous system, cells beyond the initial injury site undergo secondary degeneration, exacerbating loss of neurons, compact myelin and function. Changes in Ca2+ flux are associated with metabolic and structural changes, but it is not yet clear how flux through specific ...

journal_title：BMC neuroscience

authors： O'Hare Doig RL,Chiha W,Giacci MK,Yates NJ,Bartlett CA,Smith NM,Hodgetts SI,Harvey AR,Fitzgerald M

更新日期：2017-08-14 00:00:00

abstract：BACKGROUND:White matter hyperintensities (WMH) can lead to dementia but the underlying physiological mechanisms are unclear. We compared relative oscillatory power from electroencephalographic studies (EEGs) of 17 patients with subcortical ischemic vascular dementia, based on extensive white matter hyperintensities (SI...

journal_title：BMC neuroscience

authors： van Straaten EC,de Haan W,de Waal H,Scheltens P,van der Flier WM,Barkhof F,Koene T,Stam CJ

更新日期：2012-07-24 00:00:00

abstract：BACKGROUND:The neurological complications of HIV infection remain poorly understood. Clinically, in vivo 1H magnetic resonance spectroscopy (MRS) demonstrates brain injury caused by HIV infection even when the MRI is normal. Our goal was to undertsand the dynamics of cerebral injury by performing a longitudinal in vivo...

journal_title：BMC neuroscience

authors： Fuller RA,Westmoreland SV,Ratai E,Greco JB,Kim JP,Lentz MR,He J,Sehgal PK,Masliah E,Halpern E,Lackner AA,González RG

更新日期：2004-03-05 00:00:00

abstract：BACKGROUND:Enhanced activity of trigeminal ganglion neurons is thought to underlie neuronal sensitization facilitating the onset of chronic pain attacks, including migraine. Recurrent headache attacks might establish a chronic neuroinflammatory ganglion profile contributing to the hypersensitive phenotype. Since it is ...

journal_title：BMC neuroscience

authors： Franceschini A,Nair A,Bele T,van den Maagdenberg AM,Nistri A,Fabbretti E

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:The processing of verbal fluency tasks relies on the coordinated activity of a number of brain areas, particularly in the frontal and temporal lobes of the left hemisphere. Recent studies using functional magnetic resonance imaging (fMRI) to study the neural networks subserving verbal fluency functions have ...

journal_title：BMC neuroscience

authors： Wagner S,Sebastian A,Lieb K,Tüscher O,Tadić A

更新日期：2014-01-24 00:00:00