Abstract:
BACKGROUND:Resonant microwave absorption has been proposed in the literature to excite the vibrational states of microorganisms in an attempt to destroy them. But it is extremely difficult to transfer microwave excitation energy to the vibrational energy of microorganisms due to severe absorption of water in this spectral range. We demonstrate for the first time that, by using a visible femtosecond laser, it is effective to inactivate viruses such as bacteriophage M13 through impulsive stimulated Raman scattering. RESULTS AND DISCUSSION:By using a very low power (as low as 0.5 nj/pulse) visible femtosecond laser having a wavelength of 425 nm and a pulse width of 100 fs, we show that M13 phages were inactivated when the laser power density was greater than or equal to 50 MW/cm2. The inactivation of M13 phages was determined by plaque counts and had been found to depend on the pulse width as well as power density of the excitation laser. CONCLUSION:Our experimental findings lay down the foundation for an innovative new strategy of using a very low power visible femtosecond laser to selectively inactivate viruses and other microorganisms while leaving sensitive materials unharmed by manipulating and controlling with the femtosecond laser system.
journal_name
Virol Jjournal_title
Virology journalauthors
Tsen KT,Tsen SW,Chang CL,Hung CF,Wu TC,Kiang JGdoi
10.1186/1743-422X-4-50subject
Has Abstractpub_date
2007-06-05 00:00:00pages
50issn
1743-422Xpii
1743-422X-4-50journal_volume
4pub_type
杂志文章相关文献
Virology Journal文献大全abstract:BACKGROUND:Chronic viral hepatitis B remains a global public health concern. Currently, several drugs, such as lamivudine and telbivudine, are recommended for treatment of patients with chronic hepatitis B. However, there are no conclusive results on the comparison of the efficacy of lamivudine (LAM) and telbivudine (L...
journal_title:Virology journal
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1743-422X-7-211
更新日期:2010-09-03 00:00:00
abstract:BACKGROUND:The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. METHODS:The safety of LSDV was tested at doses of 104 and 106 plaque forming units in two strains of i...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-8-265
更新日期:2011-05-30 00:00:00
abstract:BACKGROUND:The major structural protein of coronaviruses, the membrane (M) protein, can elicit the formation of protective antibodies, but little information is available about the M protein of porcine epidemic diarrhea virus (PEDV). Identification of epitopes on the PEDV M protein will be helpful in the elucidation of...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-9-225
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Few studies have used quantitative polymerase chain reaction (qPCR) as an approach to measure virus neutralization assay endpoints. Its lack of use may not be surprising considering that sample nucleic acid extraction and purification can be expensive, labor-intensive, and rate-limiting. METHODS:Virus/antib...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-10-195
更新日期:2013-06-15 00:00:00
abstract:BACKGROUND:Aleutian mink disease virus (AMDV) is the cause of a chronic immune complex disease, Aleutian disease (AD), which is common in mink-producing countries. In 2005, implementation of an AMDV eradication programme in Finland created a need for an automated high-throughput assay. The aim of this study was to vali...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-11-141
更新日期:2014-08-08 00:00:00
abstract:BACKGROUND:During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until recently, only a few prokaryotic viruses had been described for one of the lin...
journal_title:Virology journal
pub_type: 杂志文章,评审
doi:10.1186/s12985-018-1097-1
更新日期:2018-11-23 00:00:00
abstract::More than 20 years ago, hantaviral antigens were reported in tissues of the Eurasian common shrew (Sorex araneus), Eurasian water shrew (Neomys fodiens) and common mole (Talpa europea), suggesting that insectivores, or soricomorphs, might serve as reservoirs of unique hantaviruses. Using RT-PCR, sequences of a genetic...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-4-114
更新日期:2007-10-30 00:00:00
abstract:BACKGROUND:Hepatitis B virus (HBV) causes significant morbidity and mortality globally primarily due to its ability to cause hepatitis, liver cirrhosis and hepatocellular carcinoma. The Kenya National Blood Transfusion Services screens for Hepatitis B antibodies using the chemiluminescent microparticle immunoassay meth...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-020-01447-2
更新日期:2020-11-13 00:00:00
abstract:BACKGROUND:Production of cassava (Manihot esculenta Crantz), a food security crop in sub-Saharan Africa, is threatened by the spread of cassava brown streak disease (CBSD) which manifests in part as a corky necrosis in the storage root. It is caused by either of two virus species, Cassava brown streak virus (CBSV) and ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-014-0216-x
更新日期:2014-12-20 00:00:00
abstract:BACKGROUND:H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population. Vaccination is the best strategy to control H5N1 HPAIV infection in poultry and transmission to human population. The aim of this study is to identif...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-9-97
更新日期:2012-05-23 00:00:00
abstract::On 11 March 2020, the World Health Organization (WHO) announced Corona Virus Disease (COVID-19), a disease caused by a pathogen called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pandemic. This ongoing pandemic has now been reported in 215 countries with more than 23 million confirmed cases and mor...
journal_title:Virology journal
pub_type: 杂志文章,评审
doi:10.1186/s12985-020-01416-9
更新日期:2020-10-02 00:00:00
abstract:BACKGROUND:Pear ring rot, caused by Botryosphaeria species, is responsible for substantial economic losses by causing severe recession of pear tree growth in China. Mycovirus-mediated hypovirulence in plant pathogenic fungi is a crucial biological method to control fungal diseases. METHODS:We conducted a large-scale a...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-018-1033-4
更新日期:2018-08-13 00:00:00
abstract:BACKGROUND:In mammals, interleukin 2 (IL-2) has been shown to decrease replication or attenuate pathogenicity of numerous viral pathogens (herpes simplex virus, vaccinia virus, human respiratory syncytial virus, human immunodeficiency virus) by activating natural killer cells (NK), cytotoxic T lymphocytes and expanding...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-015-0353-x
更新日期:2015-08-08 00:00:00
abstract:BACKGROUND:Human herpes virus 8 (HHV-8) is the etiologic agent associated with development of classical, AIDS-related, iatrogenic, and endemic Kaposi's sarcoma (KS). Several studies provide strong evidence that HHV-8 can be transmitted by blood transfusion. We evaluated the seroprevalence and potential risk factors of ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-7-62
更新日期:2010-03-17 00:00:00
abstract:BACKGROUND:Chikungunya virus (CHIKV) is transmitted via mosquito bite and potentially by aerosol, causing chikungunya fever and arthritic disease in humans. There are currently no licensed vaccines or antiviral therapeutics to protect against CHIKV infection in humans. Animal models recapitulating human disease, especi...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-017-0804-7
更新日期:2017-07-20 00:00:00
abstract:BACKGROUND:Human papillomavirus (HPV) bivalent and quadrivalent vaccines have been widely implemented in worldwide organized immunization programs. A nonavalent HPV vaccine is now available in several countries. The objective was to describe the fraction of squamous non-invasive high-grade cervical intraepithelial lesi...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-017-0879-1
更新日期:2017-11-06 00:00:00
abstract::Phage vB_EcoM_CBA120 (CBA120), isolated against Escherichia coli O157:H7 from a cattle feedlot, is morphologically very similar to the classic phage ViI of Salmonella enterica serovar Typhi. Until recently, little was known genetically or physiologically about the ViI-like phages, and none targeting E. coli have been ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-8-430
更新日期:2011-09-07 00:00:00
abstract:BACKGROUND:Influenza virus infections are responsible for significant morbidity worldwide and therefore it remains a high priority to develop more broadly protective vaccines. Adjuvation of current seasonal influenza vaccines has the potential to achieve this goal. METHODS:To assess the immune potentiating properties ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-015-0435-9
更新日期:2015-12-08 00:00:00
abstract::Porcine circoviruses are circular single-stranded DNA viruses that infect swine and wild boars. Two species of porcine circoviruses exist. Porcine circovirus type 1 is non pathogenic contrary to porcine circovirus type 2 which is associated with the disease known as Post-weaning Multisystemic Wasting Syndrome. Porcine...
journal_title:Virology journal
pub_type: 杂志文章,评审
doi:10.1186/1743-422X-6-60
更新日期:2009-05-18 00:00:00
abstract:BACKGROUND:Xenotransplantation using pig cells, tissues and organs may help to overcome the shortage of human tissues and organs for the treatment of tissue and organ failure. Progress in the prevention of immunological rejection using genetically modified pigs and new, more effective, immunosuppression regimens will a...
journal_title:Virology journal
pub_type: 杂志文章,评审
doi:10.1186/s12985-018-1088-2
更新日期:2018-11-08 00:00:00
abstract::Virology Journal is an exclusively on-line, Open Access journal devoted to the presentation of high-quality original research concerning human, animal, plant, insect bacterial, and fungal viruses. Virology Journal will establish a strategic alternative to the traditional virology communication process. ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-1-1
更新日期:2004-08-26 00:00:00
abstract:BACKGROUND:The amino terminus of the tobacco etch virus (TEV) capsid protein is located on the external surface of infectious TEV particles, as proposed by previous studies and an in silico model. The epsilon amino groups on the exposed lysine residues are available for chemical conjugation to any given protein, and ca...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-9-75
更新日期:2012-03-27 00:00:00
abstract::Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial and complete structures of nine out of twenty tail structural p...
journal_title:Virology journal
pub_type: 杂志文章,评审
doi:10.1186/1743-422X-7-355
更新日期:2010-12-03 00:00:00
abstract:BACKGROUND:Rhabdoviridae is one of the most ecologically diverse families of RNA viruses which can infect a wide range of vertebrates and invertebrates. Bats, among mammals, are pointed to harbor a significantly higher proportion of unknown or emerging viruses with zoonotic potential. Herein, we report the isolation of...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/s12985-018-0949-z
更新日期:2018-02-17 00:00:00
abstract:BACKGROUND:Nonstructural glycoprotein 4 (NSP4) encoded by rotavirus is the only viral protein currently believed to function as an enterotoxin. NSP4 is synthesized as an intracellular transmembrane glycoprotein and as such is essential for virus assembly. Infection of polarized Caco-2 cells with rotavirus also results ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-8-551
更新日期:2011-12-20 00:00:00
abstract:BACKGROUND:Ticks are implicated as hosts to a wide range of animal and human pathogens. The full range of microbes harbored by ticks has not yet been fully explored. METHODS:As part of a viral surveillance and discovery project in arthropods, we used unbiased high-throughput sequencing to examine viromes of ticks coll...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-11-26
更新日期:2014-02-11 00:00:00
abstract:AIM:To evaluate the efficacy and safety of Entecavir (ETV) plus adefovir (ADV) for chronic hepatitis B (CHB) patients after multiple nucleos(t)ide analogue (NAs) failure treatment. METHODS:Hepatitis B e antigen (HBeAg)-positive patients who had a suboptimal response or developed resistance to two or more previous NAs ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-10-162
更新日期:2013-05-25 00:00:00
abstract:BACKGROUND:Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression that correspond to that specific pathogen. Venezuelan equine encephalitis (VEE) is a mosquito-borne ...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-4-82
更新日期:2007-08-29 00:00:00
abstract::Six major Hepatitis C virus (HCV) genotypes and hundreds of subtypes have been identified globally. All these genotypes are generally studied for epidemiology, their vaccine development and clinical management. This article comments the frequency distribution of various HCV genotypes circulate in different areas/distr...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-7-203
更新日期:2010-08-26 00:00:00
abstract:BACKGROUND:Enteroviruses (EVs) are the leading cause of aseptic meningitis, which is the most frequent central nervous system infection worldwide. We aimed to characterize the EVs involved in an aseptic meningitis outbreak in Korea in 2008. In Korea, Echovirus type 30 (E30) and E6 have been associated with outbreaks an...
journal_title:Virology journal
pub_type: 杂志文章
doi:10.1186/1743-422X-9-38
更新日期:2012-02-15 00:00:00