The XVI International Conference on AIDS: the place to be!

Abstract:

:This editorial represents a plea to retrovirologists to attend the XVI International Conference on AIDS that will take place in Toronto, Canada between August 13-18, 2006. In short, it is vital that politicians and opinion leaders understand that basic scientists are no less committed to the worldwide battle against HIV than community activists or non-basic scientists, and the best way to demonstrate this is by showing up.

journal_name

Retrovirology

journal_title

Retrovirology

authors

Wainberg MA

doi

10.1186/1742-4690-3-9

subject

Has Abstract

pub_date

2006-02-03 00:00:00

pages

9

issn

1742-4690

pii

1742-4690-3-9

journal_volume

3

pub_type

社论
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    abstract:BACKGROUND:The HIV-1 Rev regulatory protein binds as an oligomeric complex to viral RNA mediating nuclear export of incompletely spliced and non-spliced viral mRNAs encoding the viral structural proteins. However, the biological significance of the obligatory complex formation of Rev upon the viral RNA is unclear. RES...

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    authors: Furnes C,Arnesen T,Askjaer P,Kjems J,Szilvay AM

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  • Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.

    abstract:BACKGROUND:A nef gene is present in all primate lentiviral genomes and is important for high viral loads and progression to AIDS in human or experimental macaque hosts of HIV or SIV, respectively. In these hosts, infection of the thymus results in a decreased output of naive T cells that may contribute to the developme...

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    authors: Van Nuffel A,Ariën KK,Stove V,Schindler M,O'Neill E,Schmökel J,Van de Walle I,Naessens E,Vanderstraeten H,Van Landeghem K,Taghon T,Pulkkinen K,Saksela K,Garcia JV,Fackler OT,Kirchhoff F,Verhasselt B

    更新日期:2013-11-15 00:00:00

  • Longitudinal analysis of subtype C envelope tropism for memory CD4+ T cell subsets over the first 3 years of untreated HIV-1 infection.

    abstract:BACKGROUND:HIV-1 infects a wide range of CD4+ T cells with different phenotypic properties and differing expression levels of entry coreceptors. We sought to determine the viral tropism of subtype C (C-HIV) Envelope (Env) clones for different CD4+ T cell subsets and whether tropism changes during acute to chronic disea...

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    更新日期:2020-08-06 00:00:00

  • NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase.

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    authors: Knyazhanskaya E,Anisenko A,Shadrina O,Kalinina A,Zatsepin T,Zalevsky A,Mazurov D,Gottikh M

    更新日期:2019-11-06 00:00:00

  • How to engage Cofilin.

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    pub_type: 杂志文章,评审

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    authors: Bukrinsky M

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    authors: Jeang KT

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  • Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity.

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    journal_title:Retrovirology

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    doi:10.1186/1742-4690-10-73

    authors: Singhroy DN,Mesplède T,Sabbah A,Quashie PK,Falgueyret JP,Wainberg MA

    更新日期:2013-07-17 00:00:00

  • Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection.

    abstract:BACKGROUND:Regulatory T cells (Tregs) have been shown to limit anti-viral immunity during chronic retroviral infection and to restrict vaccine-induced T cell responses. The objective of the study was to assess whether a combinational therapy of nanoparticle-based therapeutic vaccination and concomitant transient ablati...

    journal_title:Retrovirology

    pub_type: 杂志文章,评审

    doi:10.1186/s12977-016-0258-9

    authors: Knuschke T,Rotan O,Bayer W,Sokolova V,Hansen W,Sparwasser T,Dittmer U,Epple M,Buer J,Westendorf AM

    更新日期:2016-04-14 00:00:00

  • The challenge of describing the epidemiology of HTLV in the Amazon region of Brazil.

    abstract::HTLV-1 was the first described human retrovirus and was soon found to be associated with severe clinical diseases, including a devastating lymphoma/leukemia and other inflammatory diseases. Although HTLV-2 is not usually pathogenic, it is widely distributed among native Indian populations in Brazil, particularly in th...

    journal_title:Retrovirology

    pub_type: 杂志文章,评审

    doi:10.1186/s12977-020-0512-z

    authors: Ishak R,de Oliveira Guimarães Ishak M,Vallinoto ACR

    更新日期:2020-02-14 00:00:00

  • Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation.

    abstract:BACKGROUND:Toll-like receptors (TLRs) are crucial for recognition of pathogen-associated molecular patterns by cells of the innate immune system. TLRs are present and functional in CD4⁺ T cells. Memory CD4⁺ T cells, predominantly central memory cells (TCM), constitute the main reservoir of latent HIV-1. However, how TL...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-10-119

    authors: Novis CL,Archin NM,Buzon MJ,Verdin E,Round JL,Lichterfeld M,Margolis DM,Planelles V,Bosque A

    更新日期:2013-10-24 00:00:00

  • Host proteins interacting with the Moloney murine leukemia virus integrase: multiple transcriptional regulators and chromatin binding factors.

    abstract:BACKGROUND:A critical step for retroviral replication is the stable integration of the provirus into the genome of its host. The viral integrase protein is key in this essential step of the retroviral life cycle. Although the basic mechanism of integration by mammalian retroviruses has been well characterized, the fact...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-5-48

    authors: Studamire B,Goff SP

    更新日期:2008-06-13 00:00:00

  • Evidence for preferential copackaging of Moloney murine leukemia virus genomic RNAs transcribed in the same chromosomal site.

    abstract:BACKGROUND:Retroviruses have a diploid genome and recombine at high frequency. Recombinant proviruses can be generated when two genetically different RNA genomes are packaged into the same retroviral particle. It was shown in several studies that recombinant proviruses could be generated in each round of HIV-1 replicat...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-2-3

    authors: Kharytonchyk SA,Kireyeva AI,Osipovich AB,Fomin IK

    更新日期:2005-01-18 00:00:00

  • SIVdrl detection in captive mandrills: are mandrills infected with a third strain of simian immunodeficiency virus?

    abstract::A pol-fragment of simian immunodeficiency virus (SIV) that is highly related to SIVdrl-pol from drill monkeys (Mandrillus leucophaeus) was detected in two mandrills (Mandrillus sphinx) from Amsterdam Zoo. These captivity-born mandrills had never been in contact with drill monkeys, and were unlikely to be hybrids. Thei...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-1-36

    authors: van der Kuyl AC,van den Burg R,Hoyer MJ,Gruters RA,Osterhaus AD,Berkhout B

    更新日期:2004-11-01 00:00:00

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    abstract:BACKGROUND:Existing highly active antiretroviral therapy (HAART) effectively controls viral replication in human immunodeficiency virus type 1 (HIV-1) infected individuals but cannot completely eradicate the infection, at least in part due to the persistence of latently infected cells. One strategy that is being active...

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    doi:10.1186/1742-4690-10-120

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  • Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line.

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    doi:10.1186/1742-4690-5-1

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    更新日期:2008-01-04 00:00:00

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    abstract:BACKGROUND:Interferon induced transmembrane proteins 1, 2 and 3 (IFITMs) belong to a family of highly related antiviral factors that have been shown to interfere with a large spectrum of viruses including Filoviruses, Coronaviruses, Influenza virus, Dengue virus and HIV-1. In all these cases, the reported mechanism of ...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/s12977-014-0103-y

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    更新日期:2014-11-25 00:00:00

  • WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL?

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    pub_type: 评论,杂志文章

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    更新日期:2012-12-21 00:00:00

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    authors: Nangola S,Urvoas A,Valerio-Lepiniec M,Khamaikawin W,Sakkhachornphop S,Hong SS,Boulanger P,Minard P,Tayapiwatana C

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    abstract:BACKGROUND:All human immunodeficiency virus (HIV-1) uses a host tRNALys,3 as the primer for reverse transcription. The tRNALys,3 is bound to a region on the HIV-1 genome, the primer-binding site (PBS), that is complementary to the 18 terminal nucleotides of tRNALys,3. How HIV-1 selects the tRNA from the intracellular m...

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    pub_type: 杂志文章

    doi:10.1186/1742-4690-2-21

    authors: Moore-Rigdon KL,Kosloff BR,Kirkman RL,Morrow CD

    更新日期:2005-03-24 00:00:00

  • Human TRIM5alpha mediated restriction of different HIV-1 subtypes and Lv2 sensitive and insensitive HIV-2 variants.

    abstract::In order to characterize the antiviral activity of human TRIM5alpha in more detail human derived indicator cell lines over expressing wild type human TRIM5alpha were generated and challenged with HIV-1 and HIV-2 viruses pseudotyped with HIV envelope proteins in comparison to VSV-G pseudotyped particles. HIV envelope p...

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    doi:10.1186/s12977-017-0373-2

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    pub_type: 杂志文章,评审

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    journal_title:Retrovirology

    pub_type: 社论

    doi:10.1186/1742-4690-3-60

    authors: Smith SM

    更新日期:2006-09-08 00:00:00

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    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/s12977-014-0065-0

    authors: Evering TH,Kamau E,St Bernard L,Farmer CB,Kong XP,Markowitz M

    更新日期:2014-08-15 00:00:00

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    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-8-51

    authors: Cockrell AS,van Praag H,Santistevan N,Ma H,Kafri T

    更新日期:2011-06-24 00:00:00

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    abstract::Few years after HTLV-1 identification and isolation in humans, STLV-1, its simian counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1 subtype A, all human subtypes have a simian homolog. As...

    journal_title:Retrovirology

    pub_type: 杂志文章,评审

    doi:10.1186/s12977-019-0503-0

    authors: Jégado B,Kashanchi F,Dutartre H,Mahieux R

    更新日期:2019-12-16 00:00:00

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    abstract:BACKGROUND:Certain murine leukemia viruses (MLVs) are capable of inducing progressive spongiform motor neuron disease in susceptible mice upon infection of the central nervous system (CNS). The major CNS parenchymal target of these neurovirulent retroviruses (NVs) are the microglia, whose infection is largely coinciden...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-3-26

    authors: Dimcheff DE,Volkert LG,Li Y,DeLucia AL,Lynch WP

    更新日期:2006-05-12 00:00:00