The XVI International Conference on AIDS: the place to be!

Abstract:

:This editorial represents a plea to retrovirologists to attend the XVI International Conference on AIDS that will take place in Toronto, Canada between August 13-18, 2006. In short, it is vital that politicians and opinion leaders understand that basic scientists are no less committed to the worldwide battle against HIV than community activists or non-basic scientists, and the best way to demonstrate this is by showing up.

journal_name

Retrovirology

journal_title

Retrovirology

authors

Wainberg MA

doi

10.1186/1742-4690-3-9

subject

Has Abstract

pub_date

2006-02-03 00:00:00

pages

9

issn

1742-4690

pii

1742-4690-3-9

journal_volume

3

pub_type

社论
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    abstract:BACKGROUND:Eradication of HIV cannot be achieved with combination antiretroviral therapy (cART) because of the persistence of long-lived latently infected resting memory CD4(+) T cells. We previously reported that HIV latency could be established in resting CD4(+) T cells in the presence of the chemokine CCL19. To defi...

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    doi:10.1186/s12977-016-0284-7

    authors: Saleh S,Lu HK,Evans V,Harisson D,Zhou J,Jaworowski A,Sallmann G,Cheong KY,Mota TM,Tennakoon S,Angelovich TA,Anderson J,Harman A,Cunningham A,Gray L,Churchill M,Mak J,Drummer H,Vatakis DN,Lewin SR,Cameron PU

    更新日期:2016-07-26 00:00:00

  • Efficient trapping of HIV-1 envelope protein by hetero-oligomerization with an N-helix chimera.

    abstract:BACKGROUND:The N-heptad repeat region of the HIV-1 Transmembrane Envelope protein is a trimerization domain that forms part of a "six helix bundle" crucial to Envelope-mediated membrane fusion. N-heptad repeat peptides have been used as extracellular reagents to inhibit virus fusion. RESULTS:When expressed intracellul...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-2-51

    authors: Ou W,Silver J

    更新日期:2005-08-10 00:00:00

  • Digital PCR as a tool to measure HIV persistence.

    abstract::Although antiretroviral therapy is able to suppress HIV replication in infected patients, the virus persists and rebounds when treatment is stopped. In order to find a cure that can eradicate the latent reservoir, one must be able to quantify the persisting virus. Traditionally, HIV persistence studies have used real-...

    journal_title:Retrovirology

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    doi:10.1186/s12977-018-0399-0

    authors: Rutsaert S,Bosman K,Trypsteen W,Nijhuis M,Vandekerckhove L

    更新日期:2018-01-30 00:00:00

  • The challenge of describing the epidemiology of HTLV in the Amazon region of Brazil.

    abstract::HTLV-1 was the first described human retrovirus and was soon found to be associated with severe clinical diseases, including a devastating lymphoma/leukemia and other inflammatory diseases. Although HTLV-2 is not usually pathogenic, it is widely distributed among native Indian populations in Brazil, particularly in th...

    journal_title:Retrovirology

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    doi:10.1186/s12977-020-0512-z

    authors: Ishak R,de Oliveira Guimarães Ishak M,Vallinoto ACR

    更新日期:2020-02-14 00:00:00

  • Limited cross-border infections in patients newly diagnosed with HIV in Europe.

    abstract:BACKGROUND:International travel plays a role in the spread of HIV-1 across Europe. It is, however, not known whether international travel is more important for spread of the epidemic as compared to endogenous infections within single countries. In this study, phylogenetic associations among HIV of newly diagnosed patie...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-10-36

    authors: Frentz D,Wensing AM,Albert J,Paraskevis D,Abecasis AB,Hamouda O,Jørgensen LB,Kücherer C,Struck D,Schmit JC,Åsjö B,Balotta C,Beshkov D,Camacho RJ,Clotet B,Coughlan S,De Wit S,Griskevicius A,Grossman Z,Horban A,Kolu

    更新日期:2013-04-03 00:00:00

  • Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma.

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    doi:10.1186/s12977-020-00535-z

    authors: Rauch DA,Olson SL,Harding JC,Sundaramoorthi H,Kim Y,Zhou T,MacLeod AR,Challen G,Ratner L

    更新日期:2020-08-28 00:00:00

  • Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?

    abstract::HIV viruses encode a set of accessory proteins, which are important determinants of virulence due to their ability to manipulate the host cell physiology for the benefit of the virus. Although these viral proteins are dispensable for viral growth in many in vitro cell culture systems, they influence the efficiency of ...

    journal_title:Retrovirology

    pub_type: 杂志文章,评审

    doi:10.1186/1742-4690-7-35

    authors: Ayinde D,Maudet C,Transy C,Margottin-Goguet F

    更新日期:2010-04-09 00:00:00

  • HIV and the tuberculosis "set point": how HIV impairs alveolar macrophage responses to tuberculosis and sets the stage for progressive disease.

    abstract::As HIV has fueled a global resurgence of tuberculosis over the last several decades, there is a growing awareness that HIV-mediated impairments in both innate and adaptive immunity contribute to the heightened risk of tuberculosis in people with HIV. Since early immune responses to Mycobacterium tuberculosis (Mtb) set...

    journal_title:Retrovirology

    pub_type: 杂志文章,评审

    doi:10.1186/s12977-020-00540-2

    authors: Auld SC,Staitieh BS

    更新日期:2020-09-23 00:00:00

  • Memories of John N. Brady: scientist, mentor and friend.

    abstract::Friends and colleagues remember John N. Brady, Ph.D., Chief of the Virus Tumor Biology Section of the Laboratory of Cellular Oncology, who died much too young at the age of 57 on April 27, 2009 of colon cancer. John grew up in Illinois and received his Ph.D. with Dr. Richard Consigli at Kansas State University studyin...

    journal_title:Retrovirology

    pub_type: 传,社论,历史文章

    doi:10.1186/1742-4690-6-48

    authors: Pise-Masison CA,Marriott SJ

    更新日期:2009-05-19 00:00:00

  • Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques.

    abstract:BACKGROUND:Emergence of drug-resistant strains of human immunodeficiency virus type 1 (HIV-1) is a major obstacle to successful antiretroviral therapy (ART) in HIV-infected patients. Whether antiviral immunity can augment ART by suppressing replication of drug-resistant HIV-1 in humans is not well understood, but can b...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-3-97

    authors: Metzner KJ,Binley JM,Gettie A,Marx P,Nixon DF,Connor RI

    更新日期:2006-12-21 00:00:00

  • Inactivation of HIV-1 in breast milk by treatment with the alkyl sulfate microbicide sodium dodecyl sulfate (SDS).

    abstract:BACKGROUND:Reducing transmission of HIV-1 through breast milk is needed to help decrease the burden of pediatric HIV/AIDS in society. We have previously reported that alkyl sulfates (i.e., sodium dodecyl sulfate, SDS) are microbicidal against HIV-1 at low concentrations, are biodegradable, have little/no toxicity and a...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-2-28

    authors: Urdaneta S,Wigdahl B,Neely EB,Berlin CM Jr,Schengrund CL,Lin HM,Howett MK

    更新日期:2005-04-29 00:00:00

  • The expanding role of Tax in transcription.

    abstract::The viral transactivator of HTLV-I, Tax, has long been shown to target the earliest steps of transcription by forming quaternary complexes with sequence specific transcription factors and histone-modifying enzymes in the LTR of HTLV-I. However, a new study suggests that Tax preferentially transactivates the 21-bp repe...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-1-19

    authors: de la Fuente C,Kashanchi F

    更新日期:2004-07-30 00:00:00

  • Detection, characterization and regulation of antisense transcripts in HIV-1.

    abstract:BACKGROUND:We and others have recently demonstrated that the human retrovirus HTLV-I was producing a spliced antisense transcript, which led to the synthesis of the HBZ protein. The objective of the present study was to demonstrate the existence of antisense transcription in HIV-1 and to provide a better characterizati...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-4-71

    authors: Landry S,Halin M,Lefort S,Audet B,Vaquero C,Mesnard JM,Barbeau B

    更新日期:2007-10-02 00:00:00

  • Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients.

    abstract:BACKGROUND:Combination anti-viral therapies have reduced treatment failure rates by requiring multiple specific mutations to be selected on the same viral genome to impart high-level drug resistance. To determine if the common protease inhibitor resistance mutation L90M is only selected once or repeatedly on different ...

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    doi:10.1186/1742-4690-5-7

    authors: Kapoor A,Shapiro B,Shafer RW,Shulman N,Rhee SY,Delwart EL

    更新日期:2008-01-25 00:00:00

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    journal_title:Retrovirology

    pub_type: 评论,杂志文章

    doi:10.1186/1742-4690-9-115

    authors: Gillet N,Carpentier A,Barez PY,Willems L

    更新日期:2012-12-21 00:00:00

  • Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels.

    abstract:BACKGROUND:Elderly HIV-1 infected individuals progress to AIDS more frequently and rapidly than people becoming infected at a young age. To identify possible reasons for these differences in clinical progression, we performed comprehensive phenotypic analyses of CD4+ T cells from uninfected young and elderly individual...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/s12977-015-0213-1

    authors: Heigele A,Joas S,Regensburger K,Kirchhoff F

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  • Identification and characterization of diverse groups of endogenous retroviruses in felids.

    abstract:BACKGROUND:Endogenous retroviruses (ERVs) are genetic elements with a retroviral origin that are integrated into vertebrate genomes. In felids (Mammalia, Carnivora, Felidae), ERVs have been described mostly in the domestic cat, and only rarely in wild species. To gain insight into the origins and evolutionary dynamics ...

    journal_title:Retrovirology

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    doi:10.1186/s12977-015-0152-x

    authors: Mata H,Gongora J,Eizirik E,Alves BM,Soares MA,Ravazzolo AP

    更新日期:2015-03-15 00:00:00

  • Inhibition of Tat activity by the HEXIM1 protein.

    abstract:BACKGROUND:The positive transcription elongation factor b (P-TEFb) composed by CDK9/CyclinT1 subunits is a dedicated co-factor of HIV transcriptional transactivator Tat protein. Transcription driven by the long terminal repeat (LTR) of HIV involves formation of a quaternary complex between P-TEFb, Tat and the TAR eleme...

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    doi:10.1186/1742-4690-2-42

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  • OVEX1, a novel chicken endogenous retrovirus with sex-specific and left-right asymmetrical expression in gonads.

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    authors: Carré-Eusèbe D,Coudouel N,Magre S

    更新日期:2009-06-17 00:00:00

  • HIV-1 capsid is involved in post-nuclear entry steps.

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    journal_title:Retrovirology

    pub_type: 杂志文章

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    更新日期:2016-04-23 00:00:00

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    journal_title:Retrovirology

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    authors: Lassaunière R,Musekiwa A,Gray GE,Kuhn L,Tiemessen CT

    更新日期:2016-06-10 00:00:00

  • Feline immunodeficiency virus (FIV) env recombinants are common in natural infections.

    abstract:BACKGROUND:Recombination is a common feature of retroviral biology and one of the most important factors responsible for generating viral diversity at both the intra-host and the population levels. However, relatively little is known about rates and molecular processes of recombination for retroviruses other than HIV, ...

    journal_title:Retrovirology

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    doi:10.1186/1742-4690-9-61

    authors: Iyengar S,Schwartz DH

    更新日期:2012-07-25 00:00:00

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    authors: Monde K,Terasawa H,Nakano Y,Soheilian F,Nagashima K,Maeda Y,Ono A

    更新日期:2017-04-26 00:00:00

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    journal_title:Retrovirology

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    doi:10.1186/s12977-016-0248-y

    authors: Low HZ,Ahrenstorf G,Pommerenke C,Habermann N,Schughart K,Ordóñez D,Stripecke R,Wilk E,Witte T

    更新日期:2016-03-12 00:00:00

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    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/s12977-016-0318-1

    authors: Suspène R,Thiers V,Vartanian JP,Wain-Hobson S

    更新日期:2016-12-20 00:00:00

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    journal_title:Retrovirology

    pub_type: 杂志文章,评审

    doi:10.1186/s12977-018-0396-3

    authors: Pinzone MR,O'Doherty U

    更新日期:2018-02-17 00:00:00

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    abstract:BACKGROUND:HIV-1 budding is directed primarily by two motifs in Gag p6 designated as late domain-1 and -2 that recruit ESCRT machinery by binding Tsg101 and Alix, respectively, and by poorly characterized determinants in the capsid (CA) domain. Here, we report that a conserved Gag p6 residue, S40, impacts budding media...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-10-143

    authors: Watanabe SM,Chen MH,Khan M,Ehrlich L,Kemal KS,Weiser B,Shi B,Chen C,Powell M,Anastos K,Burger H,Carter CA

    更新日期:2013-11-21 00:00:00

  • No evidence of XMRV in prostate cancer cohorts in the Midwestern United States.

    abstract:BACKGROUND:Xenotropic murine leukemia virus (MLV)-related virus (XMRV) was initially identified in prostate cancer (PCa) tissue, particularly in the prostatic stromal fibroblasts, of patients homozygous for the RNASEL R462Q mutation. A subsequent study reported XMRV antigens in malignant prostatic epithelium and associ...

    journal_title:Retrovirology

    pub_type: 杂志文章

    doi:10.1186/1742-4690-8-23

    authors: Sakuma T,Hué S,Squillace KA,Tonne JM,Blackburn PR,Ohmine S,Thatava T,Towers GJ,Ikeda Y

    更新日期:2011-03-29 00:00:00