Abstract：
BACKGROUND:The role of corticosteroids in the process of labour is not well understood. Animal studies have shown the importance of cortisol secretion by the fetal adrenal gland in initiating labour in sheep. Infusion of glucocorticosteroids into the fetus has also shown to induce premature labour in sheep. Given these studies it has been postulated that corticosteroids will promote the induction of labour in women. This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology. OBJECTIVES:To determine the effects of corticosteroids for third trimester cervical ripening or induction of labour in comparison with other methods of cervical priming or induction of labour. SEARCH STRATEGY:We searched the Cochrane Pregnancy and Childbirth Group Trials Register (December 2005) and bibliographies of relevant papers. SELECTION CRITERIA:Clinical trials of corticosteroids for third trimester cervical ripening or labour induction. DATA COLLECTION AND ANALYSIS:A strategy was developed to deal with the large volume and complexity of trial data relating to labour induction. This involved a two-stage method of data extraction. We assessed trial quality. We contacted study authors for additional information. We collected adverse effects information from the trials. MAIN RESULTS:Only one small trial (66 women) was included. The primary outcome vaginal birth within 24 hours was not reported. No benefit of intramuscular administration of corticosteroids with intravenous oxytocin was found when compared with oxytocin alone. However, given the small size of this trial this result should be interpreted cautiously. AUTHORS' CONCLUSIONS:The effectiveness of corticosteroids for induction of labour is uncertain. This method of induction of labour is not commonly used and so further research in this area is probably unwarranted.
journal_name
Cochrane Database Syst Revjournal_title
The Cochrane database of systematic reviewsauthors
Kavanagh J,Kelly AJ,Thomas Jdoi
10.1002/14651858.CD003100.pub2subject
Has Abstractpub_date
2006-04-19 00:00:00pages
CD003100issue
2issn
1469-493Xpub_type
杂志文章,评审abstract：BACKGROUND:Gastro-oesophageal reflux (GOR) is commonly diagnosed in the neonatal population (DiPietro 1994), and generally causes few or no symptoms (Vandenplas 2009). Conversely, gastro-oesophageal reflux disease (GORD) refers to GOR that causes troublesome symptoms with or without complications such as damage to the ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD009817.pub2
更新日期：2014-10-15 00:00:00
abstract：BACKGROUND:Health insurance has the potential to improve access to health care and protect people from the financial risks of diseases. However, health insurance coverage is often low, particularly for people most in need of protection, including children and other vulnerable populations. OBJECTIVES:To assess the effe...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD008194.pub3
更新日期：2014-11-26 00:00:00
abstract：BACKGROUND:Premenstrual syndrome (PMS) is a common problem. Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome. Combined oral contraceptives, which provide both progestin and estrogen, have been examined for their ability to relieve premenstrual symptoms. An oral contraceptive containing d...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD006586.pub4
更新日期：2012-02-15 00:00:00
abstract：BACKGROUND:Prostaglandins have mainly been used for postpartum haemorrhage (PPH) when other measures fail. Misoprostol, a new and inexpensive prostaglandin E1 analogue, has been suggested as an alternative for routine management of the third stage of labour. OBJECTIVES:To assess the effects of prophylactic prostagland...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD000494.pub3
更新日期：2007-07-18 00:00:00
abstract：BACKGROUND:The recommended management for neonates with a possible serious bacterial infection (PSBI) is hospitalisation and treatment with intravenous antibiotics, such as ampicillin plus gentamicin. However, hospitalisation is often not feasible for neonates in low- and middle-income countries (LMICs). Therefore, alt...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD007646.pub3
更新日期：2019-04-11 00:00:00
abstract：BACKGROUND:Respiratory syncytial virus infection causes acute lung infection in infants and young children worldwide, resulting in considerable morbidity and mortality. Children with cystic fibrosis are prone to recurrent lung inflammation, bacterial colonisation and subsequent chronic airway disease, putting them at r...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD007743.pub6
更新日期：2016-07-20 00:00:00
abstract：BACKGROUND:Wilson's disease, first described by Samuel Wilson in 1912, is an autosomal recessive metabolic disorder resulting from mutations in the ATP7B gene. The disease develops as a consequence of copper accumulating in affected tissues. There is no gold standard for the diagnosis of Wilson's disease, which is ofte...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD012267.pub2
更新日期：2019-11-19 00:00:00
abstract：BACKGROUND:Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. OBJECTIVES:To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. SEARCH STRATEGY:We searched CENTRAL (2010, Issue 3) which contains the Acute Respiratory Infecti...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003123.pub3
更新日期：2011-06-15 00:00:00
abstract：BACKGROUND:Anterior vaginal repair (anterior colporrhaphy) is an operation traditionally used for moderate or severe stress urinary incontinence in women. About a third of adult women experience urinary incontinence. OBJECTIVES:To determine the effects of anterior vaginal repair (anterior colporrhaphy) on stress or mi...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001755
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Heat and cold therapy are often used as adjuncts in the treatment of rheumatoid arthritis by rehabilitation specialists. OBJECTIVES:To evaluate the effects of heat and cold on objective and subjective measures of disease activity in patients with rheumatoid arthritis. SEARCH STRATEGY:We searched Medline, E...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD002826
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Anxiety disorders are the most common mental health problems. They are chronic and unremitting. Effective treatments are available, but access to services is limited. Media-delivered behavioural and cognitive behavioural interventions (self-help) aim to deliver treatment with less input from professionals co...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD005330.pub4
更新日期：2013-09-09 00:00:00
abstract：BACKGROUND:Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder of neuromuscular transmission. Treatments attempt to overcome the harmful autoimmune process, or improve residual neuromuscular transmission OBJECTIVES:The objective was to examine the efficacy of treatment in Lambert-Eaton myasthenic syndro...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003279.pub3
更新日期：2011-02-16 00:00:00
abstract：BACKGROUND:Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder of unknown aetiology. Current pharmacological treatments have limited value. Hypnotherapy has been reported to have beneficial effects for IBS symptoms. OBJECTIVES:To evaluate the efficacy of hypnotherapy for the treatment of ir...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD005110.pub2
更新日期：2007-10-17 00:00:00
abstract：BACKGROUND:Many smokers give up smoking on their own, but materials that provide a structured programme for smokers to follow may increase the number who quit successfully. OBJECTIVES:The aims of this review were to determine the effectiveness of different forms of print-based self-help materials that provide a struct...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD001118.pub4
更新日期：2019-01-09 00:00:00
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journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD005506.pub4
更新日期：2009-04-15 00:00:00
abstract：BACKGROUND:Epithelial ovarian cancer presents at an advanced stage in the majority of patients. These women require chemotherapy and surgery for optimal treatment. Conventional treatment is to perform surgery first and then give chemotherapy. However, it is important to determine whether there is any advantage to using...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD005343.pub2
更新日期：2007-10-17 00:00:00
abstract：BACKGROUND:Despite evidence supporting the effectiveness of diabetic retinopathy screening (DRS) in reducing the risk of sight loss, attendance for screening is consistently below recommended levels. OBJECTIVES:The primary objective of the review was to assess the effectiveness of quality improvement (QI) intervention...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD012054.pub2
更新日期：2018-01-15 00:00:00
abstract：BACKGROUND:The burden of cardiovascular disease world-wide is one of great concern to patients and health care agencies alike. Cardiac rehabilitation aims to restore patients with heart disease to health through exercise only based rehabilitation or comprehensive cardiac rehabilitation. OBJECTIVES:To determine the eff...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001800
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Cardiac rehabilitation (CR) is a complex multifaceted intervention consisting of three core modalities: education, exercise training and psychological support. Whilst exercise and psychological interventions for patients with coronary heart disease (CHD) have been the subject of Cochrane systematic reviews, ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD008895.pub2
更新日期：2011-12-07 00:00:00
abstract：BACKGROUND:Children with developmental speech sound disorders have difficulties in producing the speech sounds of their native language. These speech difficulties could be due to structural, sensory or neurophysiological causes (e.g. hearing impairment), but more often the cause of the problem is unknown. One treatment...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD009383.pub2
更新日期：2015-03-25 00:00:00
abstract：BACKGROUND:Amniotomy (the deliberate rupture of membranes) was described almost two centuries ago and since then has been used both for induction and augmentation of labour - which are common obstetric practices. Trends have shown a rise in the induction rates over the last decade and data suggest that the rate of labo...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD010626.pub2
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Numerous medications are available for the acute treatment of migraine in adults, and some have now been approved for use in children and adolescents in the ambulatory setting. A systematic review of acute treatment of migraine medication trials in children and adolescents will help clinicians make evidence-...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD005220.pub2
更新日期：2016-04-19 00:00:00
abstract：BACKGROUND:Systemic androgen deprivation therapy (ADT), also referred to as hormone therapy,ÃÂ has long been the primary treatment for metastatic prostate cancer. Additional agents have been reserved for the castrate-resistant disease stage when ADT start becoming less effective. Abiraterone is an agent with an establi...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD013245.pub2
更新日期：2020-12-12 00:00:00
abstract：BACKGROUND:'Scared Straight' and other programmes involve organised visits to prison by juvenile delinquents or children at risk for criminal behavior. programmes are designed to deter participants from future offending through first-hand observation of prison life and interaction with adult inmates. These programmes r...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD002796
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Asthma patients who continue to experience symptoms despite taking regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) and anti-leukotrienes (LTRA) are two treatment options that could be considered as add-on therapy to ICS. OBJECTIVES:To compare the saf...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003137.pub5
更新日期：2014-01-24 00:00:00
abstract：BACKGROUND:Drugs can prevent postoperative nausea and vomiting, but their relative efficacies and side effects have not been compared within one systematic review. OBJECTIVES:The objective of this review was to assess the prevention of postoperative nausea and vomiting by drugs and the development of any side effects....
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD004125.pub3
更新日期：2017-07-17 00:00:00
abstract：BACKGROUND:This is an updated version of the original Cochrane review published in Issue 2, 2007. The role of radiotherapy (both pelvic external beam radiotherapy (EBRT) and vaginal intracavity brachytherapy (VBT)) in stage I endometrial cancer following hysterectomy remains controversial. OBJECTIVES:To assess the eff...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003916.pub3
更新日期：2012-03-14 00:00:00
abstract：BACKGROUND:Fluid excess may place patients undergoing surgery at risk for various complications. Hypertonic saline (HS) maintains intravascular volume with less intravenous fluid than isotonic salt (IS) solutions, but may increase serum sodium. OBJECTIVES:To determine the benefits and harms of HS versus IS solutions a...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD005576.pub2
更新日期：2010-01-20 00:00:00
abstract：BACKGROUND:A promising approach to the treatment of chronic ischaemic heart disease (IHD) and heart failure is the use of stem cells. The last decade has seen a plethora of randomised controlled trials (RCTs) developed worldwide which have generated conflicting results. OBJECTIVES:The critical evaluation of clinical e...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD007888.pub2
更新日期：2014-04-29 00:00:00
abstract：BACKGROUND:Prayer is an ancient and widely used intervention for alleviating illness and promoting good health. This review focuses specifically on intercessory prayer, which is organised, regular and committed, and those who practise it will almost inevitably hold some committed belief that they are praying to God. Wh...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD000368
更新日期：2000-01-01 00:00:00
