Abstract:
:As molecular biology has developed, several new diagnostic techniques have found application in the clinical setting. The use of the polymerase chain reaction (PCR) assay to study the molecular biology of microbial organisms has led to unparalleled advances, largely due to the rapidity with which results can be obtained. The sensitivity and specificity of PCR detection of viral DNA for diagnostic purposes are remarkable. With such excellent sensitivity, PCR is destined to become a useful diagnostic tool in herpesvirus infections. However, it is well known that herpesviruses establish latency after primary infections and that they can often be reactivated under various conditions. Because of the high sensitivity of PCR, detection of virus sequences by this method does not necessarily imply a disease state. We must be careful not to overdiagnose conditions in a clinical setting based on a PCR assay.
journal_name
Nagoya J Med Scijournal_title
Nagoya journal of medical scienceauthors
Morishima Tkeywords:
subject
Has Abstractpub_date
1999-11-01 00:00:00pages
83-97issue
3-4eissn
0027-7622issn
2186-3326journal_volume
62pub_type
杂志文章,评审abstract::Accessibility to health care services in Thailand is generally good, but a few areas in the country are difficult to reach. The purpose of this study was to investigate the accessibility of health care services in rural and remote areas of Thailand. It was conducted in 16 remote villages within a catchment area with a...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2013-08-01 00:00:00
abstract::Respiratory exposure to asbestos fibers has been associated with diffuse malignant mesothelioma (DMM) in humans. Despite advancements in the molecular analyses of human DMM and the development of animal models, the carcinogenic mechanisms of the disease remain unclear. There are basically three hypotheses regarding th...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,评审
doi:
更新日期:2009-02-01 00:00:00
abstract::The aim of this study was to identify the socio-demographic characteristics, knowledge, attitude and accessibility factors related to the utilization of antenatal care (ANC) service among pregnant women in the Kham District, Laos. Data for this cross-sectional study were collected in July 2008, using a two-stage clust...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2010-02-01 00:00:00
abstract::A 67-year-old man underwent posterior cervical decompression surgery for ossification of the posterior longitudinal ligament (OPLL) with fixation using cervical pedicle screws (CPSs) guided by intraoperative 3D image-based navigation. Intraoperatively, while creating the screw hole using the navigation probe, the virt...
journal_title:Nagoya journal of medical science
pub_type:
doi:10.18999/nagjms.82.4.799
更新日期:2020-11-01 00:00:00
abstract::Communication errors are the most important cause of adverse events in healthcare. The current study aimed to improve hospital-wide employee teamwork and reduce adverse medical events for patients arising from miscommunication. In our hospital, when patient safety incidents and accidents occur, staff from various occu...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.82.4.697
更新日期:2020-11-01 00:00:00
abstract::The effects of intravenous administration of iloprost, a prostacyclin analogue, on myocardial energy metabolism and myocardial blood flow (MBF) were examined in anesthetized open-chest dogs subjected to 60 min of myocardial ischemia by coronary ligation. Iloprost administration at levels of 0.1 or 0.2 micrograms/kg/mi...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::The catalytic subunit of human DNA polymerase (pol) delta, p125, was expressed in recombinant baculovirus-infected insect cells, separated from a baculovirus-encoded DNA polymerase, and was purified to homogeneity by affinity trapping with a histidine-octapeptide at the C-terminus of p125 as the ligand. Purified p125 ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::Aging is accelerated by metabolic and cardiovascular diseases, and the risk of these diseases increases with age. Obesity is an important risk factor for many age-related diseases and is linked to reduced telomere length in white blood cells. We investigated whether cardiac senescence might be enhanced in DahlS.Z-Lepr...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2014-02-01 00:00:00
abstract::Curved intertrochanteric varus osteotomy (CVO) is one of the good surgical procedures for avascular necrosis of the femoral head (ANFH) patients. However, some patients with failed CVO are converted to total hip arthroplasty (THA) as a salvage operation. We compared the clinical and radiographic outcomes of 10 hips co...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::Yokukansankachimpihange (YKSCH), a traditional Japanese medicine, is widely used for the amelioration of the behavioral and psychological symptoms of dementia with digestive dysfunction. Regardless of its successful use for digestive dysfunction, the effect of YKSCH on body weight was unknown. Furthermore, if YKSCH in...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.79.3.351
更新日期:2017-08-01 00:00:00
abstract::Since smoking is implicated in many diseases, medical professionals are expected to contribute to the reduction of smoking rates in their practice. Medical students are also expected to learn the importance of practical measures against smoking. This study surveyed the smoking rates and attitudes to smoking among medi...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract::Disorientation responses of animals exposed to microgravity produced by parabolic aircraft flights and also in-space experiments were reviewed. Disoriented postures in floating are largely species-dependent. Reflexive lowered tone of gravity-bearing extensor muscles by labyrinthectomy is not seen in mammals (hamster a...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::A 47-year-old woman diagnosed with Marfan syndrome underwent valve-sparing aortic root replacement for aortic regurgitation and annulo-aortic ectasia. Her cardiac function was normal. Preoperative coronary angiography did not demonstrate any stenosis. The David reimplantation procedure with a 28-mm Valsalva graft was ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2015-08-01 00:00:00
abstract::Little is known about the carbohydrate structure of the platelet von Willebrand factor (vWf). We have analyzed N-linked oligosaccharides from both plasma and platelet vWf by Fluorophore-Assisted-Carbohydrate Electrophoresis (FACE) and isoelectric focusing before and after digestion of the proteins with neuraminidase. ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::The number of pollinosis patients in Japan has significantly increased over the past 20 years. The majority of genome-wide association studies (GWAS) on pollinosis have been conducted in subjects of European descent, with few studies in Japanese populations. The aim of our GWAS was to identify genetic loci associated ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.80.1.109
更新日期:2018-02-01 00:00:00
abstract::A new hypothesis for the origin of metastases is presented. It assumes that a cancer-transformed gene in a primary tumour is incorporated in its identical form via a virus-vector function into biologically potent recipient cells in other organs, such as stem cells, multipotent cells or cells in an early phase of divis...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2013-02-01 00:00:00
abstract::Prostate specific antigen (PSA) testing plays a major role in prostate cancer screening; however, the low positive predictive value of PSA testing leads to many unnecessary biopsies. Genetic background is one of factors that could cause it. That's why an association between genetic background and PSA levels should be ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,多中心研究
doi:
更新日期:2013-02-01 00:00:00
abstract::Temporary threshold shifts (TSSs) in vibrotactile perception produced by continuous vibration and repetitive shocks having one complete cycle of a 100 Hz sine wave and exponential decays. The repetition rate of the cycles was 5, 25, 50, or 100/s, while the root-mean-square (r.m.s.) acceleration measured over exposure ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::API2-MALT1 translocation-positive gastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT) lymphoma is thought to transform to diffuse large B-cell lymphoma (DLBCL) rarely. A 69-year-old man presented with epigastralgia. Esophagogastroduodenoscopy showed multiple ulcerations in the stomach. Endoscop...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.79.2.251
更新日期:2017-02-01 00:00:00
abstract::Neoadjuvant chemotherapy (NAC) using the combination of anthracycline and taxanes is the standard regimen for patients with primary breast cancer. Among the taxanes, conventional paclitaxel (PTX) and docetaxel have usually been adopted in the neoadjuvant or adjuvant setting. Nanoparticle albumin-bound paclitaxel (nab-...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.82.3.457
更新日期:2020-08-01 00:00:00
abstract::Umbilical metastasis from intra-abdominal or pelvic malignancy, which is called Sister Mary Joseph's nodule (SMJN), is rare, and it has a poor prognosis. Its most common primary sites are the stomach and ovaries. SMJN caused by colon cancer is uncommon. A 42-year-old woman visited local clinics with complaints of an u...
journal_title:Nagoya journal of medical science
pub_type:
doi:10.18999/nagjms.81.2.325
更新日期:2019-05-01 00:00:00
abstract::Surgeons focus on the period of absence from work during the initial treatment of breast cancer. The aim of this study was to determine surgeons' perceptions and awareness regarding the necessary period of absence from work during breast cancer treatment. We created a questionnaire for all surgeons involved in breast ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract::We attempted to clarify the storage iron metabolism from the change in the serum ferritin level. We assumed that the nonlinear decrease in serum ferritin was caused by serum ferritin increase in iron mobilization. Under this assumption, we determined both ferritin and hemosiderin iron levels by computer-assisted simul...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract::Binding of epidermal growth factor (EGF) to its receptor was evaluated in the four cultured choriocarcinoma cell lines BeWo, NaUCC-1, NaUCC-2, and NaUCC-3. Also, the effect of the anti-tumor drugs actinomycin-D (Act-D) and methotrexate (MTX) on the EGF receptor binding was investigated in these cell lines. Incubation ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::Dialysis-induced hypotension, the sharp decrease in blood pressure occurring during hemodialysis, remains one of the most difficult problems associated with hemodialysis even today. However, there is yet no established theory to explain the mechanism triggering dialysis-induced hypotension. This review attempts to off...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,评审
doi:
更新日期:1992-03-01 00:00:00
abstract::Malignant lymphoma is a heterogeneous category embracing three major types of lymphoid neoplasms: B cell neoplasms, T and NK cell neoplasms, and Hodgkin lymphoma. Within each type, distinct disease entities are defined based on a combination of morphology, immunophenotype, genetic features and clinical syndromes, the ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract::Visual dysfunction can be caused by several abnormalities, including dysfunctions in the visual cortex and retina. Our aim was to investigate changes in visual evoked brain responses in the primary visual cortex associated with Parkinson's disease (PD). Sixteen healthy control subjects and ten patients with PD partici...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.79.2.147
更新日期:2017-02-01 00:00:00
abstract::Syntrophins are the cytoplasmic peripheral proteins of dystrophin glycoprotein complex, of which five (alpha l, beta 1, beta 2, gamma 1 and gamma 2) isoforms have been identified so far. Respective syntrophin isoforms are encoded by different genes but have similar domain structures. At the sarcolemma of skeletal musc...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2008-08-01 00:00:00
abstract::A total of 483 hips treated by primary total hip arthroplasty (THA) were investigated to evaluate the surgical skill of the performing surgeon. Surgical trainees operated on 259 hips and instructors on 224 hips. The average age of the patients at the time of THA in the trainee and instructor group was 61.9 and 60.8 ye...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2015-02-01 00:00:00
abstract::The purpose of this study was to demonstrate the characteristics of the Instrumental Activities of Daily Living (IADL) ability, evaluated by the Assessment of Motor and Process Skills (AMPS), and everyday memory functions (the memory necessary for daily life), assessed by the Rivermead Behavioral Memory Test (RBMT) in...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00